Inflammation and Alzheimer's disease.

abstract：:To evaluate the results of post-operative chemoirradiation for gastric carcinoma. The records of 58 patients who underwent resection for gastric carcinoma were retrospectively reviewed. Forty-six patients had complete resection without any residual disease but with high-risk factors of relapse. Twelve patients had mic...

journal_title：International journal of clinical practice

authors： Bora H,Unsal D,Akmansu M

更新日期：2004-05-01 00:00:00

abstract：:Exaggerated reactions to insect bites are characteristic of patients with haemoproliferative disorders, particularly chronic lymphocytic leukaemia (CLL). Skin lesions usually appear after the diagnosis of leukaemia and seem unrelated to laboratory findings, disease course or therapy. Rarely, the eruption may precede t...

journal_title：International journal of clinical practice

authors： Cocuroccia B,Gisondi P,Gubinelli E,Girolomoni G

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:The ENDURANCE study evaluated the efficacy of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor, in men with erectile dysfunction (ED), by measuring the duration of erection leading to successful intercourse using a stopwatch as the assessment instrument. METHODS:This was a randomised, multicentre, dou...

journal_title：International journal of clinical practice

authors： Rosenberg MT,Adams PL,McBride TA,Roberts JN,McCallum SW

更新日期：2009-01-01 00:00:00

abstract：AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...

journal_title：International journal of clinical practice

authors： Drake MJ,MacDiarmid S,Chapple CR,Esen A,Athanasiou S,Cambronero Santos J,Mitcheson D,Herschorn S,Siddiqui E,Huang M,Stoelzel M

更新日期：2017-05-01 00:00:00

abstract：:This randomised, crossover study compared the efficacy, safety, acceptability and patient preference of two multidose powder inhalers (MDPIs)--beclomethasone dipropionate Easyhaler (BDP-EH) and budesonide Turbohaler (BUD-TH)--in 79 stable asthmatics who used inhaled steroids but had no experience of MDPIs. After eight...

journal_title：International journal of clinical practice

authors： Jäger L,Laurikainen K,Leinonen M,Silvasti M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Although there is a general agreement for the recommendation of the influenza vaccine to persons with chronic obstructive pulmonary disease (COPD), the magnitude of clinical effectiveness and benefit from the annual vaccination is controversial. We assessed the effects of annual influenza vaccination on wint...

journal_title：International journal of clinical practice

authors： Vila-Córcoles A,Ochoa O,de Diego C,Valdivieso A,Herreros I,Bobé F,Alvarez M,Juárez M,Guinea I,Ansa X,Saún N

更新日期：2008-01-01 00:00:00

abstract：:The potential effect of orlistat on cardiovascular co-morbidities may have been previously underestimated. This study assesses the efficacy of orlistat therapy for weight loss and cardiovascular risk factor reduction in obese patients with cardiovascular risk. This was a 54-week, double-blind, randomised, placebo-cont...

journal_title：International journal of clinical practice

authors： Broom I,Wilding J,Stott P,Myers N,UK Multimorbidity Study Group.

更新日期：2002-09-01 00:00:00

abstract：AIMS:To evaluate in a real-world setting the effectiveness of exenatide once-weekly (ExQW) in patients with T2D and to determine predictors of glycaemic and weight response to this drug at 6 months. METHODS:Observational, retrospective, multicenter study in adult patients with T2D and BMI ≥30 kg/m2 from 4 tertiary Spa...

journal_title：International journal of clinical practice

authors： Gorgojo-Martínez JJ,Gargallo-Fernández MA,Brito-Sanfiel M,Lisbona-Catalán A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Asthma diagnosis is based on the presence of symptoms and the demonstration of airflow variability. Airway inflammation measured by fractional exhaled nitric oxide, measured at a flow rate of 50 ml/s (FE(NO50)) remains a controversial diagnostic tool. AIM:To assess the ability of FE(NO50) to identify bronch...

journal_title：International journal of clinical practice

authors： Schleich FN,Asandei R,Manise M,Sele J,Seidel L,Louis R

更新日期：2012-02-01 00:00:00

abstract：:A case of alexia without agraphia is presented. It is a rare but classic disconnection syndrome, first described by Dejerine in 1892. Recent advances in modern neuroimaging techniques such as FLAIR MRI can now localise in vivo the site of origin of the syndrome, especially when computerised axial tomogram of the brain...

journal_title：International journal of clinical practice

authors： Imtiaz KE,Nirodi G,Khaleeli AA

更新日期：2001-04-01 00:00:00

abstract：:Prostate cancer remains a most intriguing condition, which poses unique challenges. On reviewing recent literature on localised disease (confined within the capsule T1 or T2, N0, M0), it would seem that it is over treated, resulting in significant morbidity. We now have strong evidence, however, that there can be mort...

journal_title：International journal of clinical practice

authors： Hodgson D,Acher P,Cahill D

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Guidelines for injury care are increasingly moving away from surgical management towards less invasive procedures but there is a knowledge gap on how these recommendations are influencing practice. We aimed to assess inter-hospital variation in surgical intensity for injury admissions and evaluate the correl...

journal_title：International journal of clinical practice

authors： Patton MP,Moore L,Farhat I,Tardif PA,Gonthier C,Belcaid A,Lauzier F,Turgeon A,Clément J

更新日期：2020-11-01 00:00:00

abstract：:The aim of thromboprophylaxis is to minimise the incidence of clinically relevant venous thromboembolism (VTE) but in many trials designed to determine the efficacy of thromboprophylactic agents, asymptomatic VTE is included in the primary endpoint. Since asymptomatic events occur much more frequently than symptomatic...

journal_title：International journal of clinical practice

authors： Lalourcey L

更新日期：2003-05-01 00:00:00

abstract：:The misery of living with atopic eczema (syn. dermatitis, AD) cannot be overstated for it may have a profoundly negative effect on the health-related quality of life (HRQoL) of children and their family unit in many cases. As it is one of the commonest chronic relapsing childhood dermatosis (UK lifetime prevalence 16-...

journal_title：International journal of clinical practice

authors： Lewis-Jones S

更新日期：2006-08-01 00:00:00

abstract：:General practitioners (GPs) are increasingly involved in the selective opportunistic case finding of osteoporosis and treatment of this condition. An open access bone densitometry service has existed for GPs in the Cardiff area since 1993. The purpose of this study was to assess the effectiveness of this service, part...

journal_title：International journal of clinical practice

authors： Sim MF,Stone M,Johansen A,Ho P,Pettit RJ,Evans WD

更新日期：2004-03-01 00:00:00

abstract：:Major concerns remain about the reliability of tympanic thermometers. The aim of this study was to investigate the agreement between rectal and tympanic thermometry and compare this with the repeatability of each method in patients with acute stroke. Tympanic temperature readings were from 0.7 degrees C below to 0.8 d...

journal_title：International journal of clinical practice

authors： Christensen H,Boysen G

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:In 2006, the American Diabetes Association and the European Association for the Study of Diabetes established a consensus algorithm (ADA/EASD-2006) for the adjustment of drug therapy for type 2 diabetes mellitus (T2DM). AIMS:To study glycaemic control in T2DM patients and the implementation of the ADA/EASD-...

journal_title：International journal of clinical practice

authors： Alvarez-Guisasola F,Guiada Study Group.

更新日期：2014-01-01 00:00:00

abstract：:Primary intracranial melanomas are rare and occur mainly in young adults. Originating from leptomeningeal melanoblasts and extending into the parenchyma, the tumours closely resemble meningiomas, from which they are radiologically difficult to distinguish despite progress in neuroimaging. Definitive diagnosis is usual...

journal_title：International journal of clinical practice

authors： Farnsworth TA

更新日期：1998-09-01 00:00:00

abstract：:Nitrates are useful drugs in cardiovascular medicine. They have a presumed vasovagal effect, which is a rare but often under-recognised complication that is partly caused by central inhibition of the sympathetic nervous system. However, no consistent variable associated with the presumed vasovagal effects following ni...

journal_title：International journal of clinical practice

authors： Lydakis C,Chaudary AY,Lip GY

更新日期：1998-09-01 00:00:00

abstract：INTRODUCTION:Niacin is underutilised because of flushing. Lack of a quantitative tool to assess niacin-induced flushing has precluded the objective evaluation of flushing associated with extended-release (ER) niacin formulations. We developed the Flushing Symptom Questionnaire((c)) (FSQ), a quantitative tool to assess ...

journal_title：International journal of clinical practice

authors： Paolini JF,Mitchel YB,Reyes R,Thompson-Bell S,Yu Q,Lai E,Watson DJ,Norquist JM,Sisk CM,Bays HE

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Ultrasonography is increasingly used by clinicians to identify abdominal aortic aneurysms (AAA). We performed a systematic review and meta-analysis comparing the accuracy of non-radiologist performed ultrasound (NRPUS) for AAA disease to the 'gold standard' of radiologist performed aortic imaging (RPI), intr...

journal_title：International journal of clinical practice

authors： Concannon E,McHugh S,Healy DA,Kavanagh E,Burke P,Clarke Moloney M,Walsh SR

更新日期：2014-09-01 00:00:00

abstract：AIMS:The aims of this study were to determine the diagnostic yield of a dedicated heart failure diagnosis clinic and the impact of using different guideline recommended N-terminal pro B-type natriuretic peptide (NT-proBNP) referral thresholds on diagnosis and referral patterns. METHODS AND RESULTS:Patients referred by...

journal_title：International journal of clinical practice

authors： Fazal IA,Bhagra SK,Bailey KM,Dermot Neely R,MacGowan GA,Skinner JS

更新日期：2015-11-01 00:00:00

abstract：:The aim of this study was to identify the aerobic and the anaerobic microorganisms which can be related to duct ectasia. The patients were divided into two groups. Group 1 comprised 100 patients with coloured nipple discharge (duct ectasia group), and Group 2 (the control group) was composed of 50 patients without nip...

journal_title：International journal of clinical practice

authors： Rahal RM,Júnior RF,Reis C,Pimenta FC,Netto JC,Paulinelli RR

更新日期：2005-09-01 00:00:00

abstract：:Marijuana is the most commonly used illicit drug while its abuse and dependence has an increasing prevalence among the young population. Marijuana smoking affects the circulatory system triggering various cardiovascular events. Of note, recent case reports indicate a possible association with atrial fibrillation (AF)....

journal_title：International journal of clinical practice

authors： Korantzopoulos P,Liu T,Papaioannides D,Li G,Goudevenos JA

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:We aimed to evaluate the use of computed tomography (CT) as the first imaging modality in patients with renal colic and microscopic haematuria. METHODOLOGY:The patients that presented to the emergency service of six health centers with renal colic between January 2017 and January 2018 and were found to have ...

journal_title：International journal of clinical practice

authors： Sen V,Ongun S,Sahin MO,Irer B,Kizer O,Dogan B,Yildiz G

更新日期：2020-11-09 00:00:00

abstract：:Cystic fibrosis (CF) is one of the commonest lethal inherited conditions among Caucasians. It affects multiple organ systems and exhibits a range of clinical problems of varying severity. Life expectancy has improved in recent years as treatment regimes have become more intensive, but current treatments are expensive,...

journal_title：International journal of clinical practice

authors： Lees CM,Smyth RL

更新日期：2000-04-01 00:00:00

abstract：AIMS:The IMPROVE observational study evaluated the safety profile and effectiveness of biphasic insulin aspart 30/70 (BIAsp 30) in patients with type 2 diabetes in routine practice in 11 countries. METHODS:Patients who initiated insulin therapy with, or switched existing insulin therapy to, BIAsp 30 in routine care we...

journal_title：International journal of clinical practice

authors： Valensi P,Benroubi M,Borzi V,Gumprecht J,Kawamori R,Shaban J,Shah S,Shestakova M,Wenying Y,IMPROVE Study Group Expert Panel.

更新日期：2009-03-01 00:00:00

abstract：:Obesity is the major risk factor for the development of hypertension. This association accentuates the risk of cardiovascular disease, as it is frequently accompanied by the components of the metabolic syndrome. This randomised open parallel study evaluated the chronic effects of moxonidine--a selective imidazoline re...

journal_title：International journal of clinical practice

authors： Sanjuliani AF,de Abreu VG,Francischetti EA

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:Serum sodium overcorrection and hypernatremia are significant health risks. We conducted a systematic review and meta-analysis to evaluate the risks of vaptans in hypernatremia and serum sodium overcorrection. METHODS:We searched PubMed, Embase, and CENTRAL for randomised controlled trials. We included studi...

journal_title：International journal of clinical practice

authors： Zhou Y,Yang W,Liu G,Gao W

更新日期：2020-12-17 00:00:00

abstract：:Buprenorphine is a semi-synthetic opioid derived from thebaine. The transdermal formulation of buprenorphine has been available in Belgium for 3 years, during which time the Pain Clinic of the St Elisabeth of Verviers Hospital has gained experience in the use of transdermal buprenorphine for the treatment of moderate-...

journal_title：International journal of clinical practice

authors： Louis F

更新日期：2006-10-01 00:00:00