Abstract:
:Schizophrenia is present in all human populations with approximately the same incidence. Why does such illness persist given that it is associated with a reproductive disadvantage? What is the balancing advantage? A possible explanation is linked to human language. According to this hypothesis schizophrenia occurs as a manifestation of genetic diversity associated with language--the function by which Homo sapiens has separated from other primate species. Language originated by a genetic mutation that allowed the cerebral hemispheres to develop with a degree of specialization (or lateralization) reflected in cerebral asymmetries. Individuals with schizophrenia show lesser structural and functional brain asymmetries than the population as a whole, and this finding can be interpreted as a delay, or failure in, establishing hemispheric dominance for language. We review recent evidence supporting this theory.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Berlim MT,Mattevi BS,Belmonte-de-Abreu P,Crow TJdoi
10.1053/comp.2003.50003subject
Has Abstractpub_date
2003-01-01 00:00:00pages
7-14issue
1eissn
0010-440Xissn
1532-8384pii
S0010440X03000233journal_volume
44pub_type
杂志文章,评审abstract::The study aims to identify psychopathologic variables in cannabis-induced psychosis and recent-onset primary psychoses using the Symptom Checklist-90-R and the Psychiatric Research Interview for Substance and Mental Disorders. A sample of 181 subjects with psychotic symptoms and cannabis use referred to the psychiatry...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.04.013
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The prognosis for eating disorders (ED) is unsatisfactory, and the literature about outcome indicators is controversial. The present study evaluates the roles of self-esteem, personality disorders (PD), and dissociation as outcome predictors. METHOD:Fifty-seven ED outpatients were recruited from a population...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.03.024
更新日期:2013-10-01 00:00:00
abstract::This study employed grade of membership (GoM) analysis in a clinical setting to determine if the DSM-III-R personality disorder (PD) diagnostic criteria cluster into recognizable disorders resembling the official axis II nosology. The GoM model, based on fuzzy-set theoretic concepts, explicitly examines medical diagno...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(99)90079-2
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:Personality in patients with psychosis, and particularly its relation to psychotic symptoms in recent onset of psychosis (ROP) patients, is understudied. The aims of this research were to study the relation between dimensional and categorical clinical personality traits and symptoms, as well as the effects th...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2017.01.006
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:Childhood sexual abuse (CSA) is increasing, and current studies should address issues such as stigmas and casual attitudes that may be amenable to intervention. Thus, we aimed to investigate the effects of education on the attitudes of medical students toward CSA survivors. METHOD:We divided medical students...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2012.01.003
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:There is a lack of data about residual symptoms in Chinese patients with depression. The aim of this study was to evaluate the association of residual symptoms with social functional impairment in these patients. METHODS:This was a multicenter cross-sectional study conducted in 11 hospitals in eight cities o...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2020.152164
更新日期:2020-01-22 00:00:00
abstract::The aim of the present study was to obtain standardized scores that correspond with the raw scores on the four Rasch scales of the Benzodiazepine Dependence-Self Report Questionnaire (Bendep-SRQ). The eligible normative group for standardization of the Bendep-SRQ scales consisted of 217 general practice (GP) patients,...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2001.26276
更新日期:2001-09-01 00:00:00
abstract::Patients who meet DSM-III-R criteria for a diagnosis of panic disorder often show a complex mixture of psychopathological symptoms, including panic attacks (spontaneous and situational), anxiety (anticipatory and generalized), phobias (fear and avoidance), depression/dysphoria, and social and occupational disability. ...
journal_title:Comprehensive psychiatry
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/0010-440x(91)90003-u
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:This cross-sectional study explored the prevalence of disordered eating attitudes, body shape concerns, and social anxiety and depressive symptoms in male and female medical students in China. METHOD:Four hundred eighty-seven students from Central South University (Hunan Province, Changsha City, China) compl...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2009.11.007
更新日期:2010-09-01 00:00:00
abstract::This study investigated several aspects of the validity of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition avoidant personality disorder (APD) construct, with emphasis on the psychometric properties of the diagnostic criteria and the prototype nature of the construct. A sample of 1,058 patien...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.comppsych.2006.01.006
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:The aim of the study was to investigate the relationship of dysfunctional attitudes, self-esteem, personality, and depression with Internet addiction in university students. METHODS:A total of 720 university students participated in the study in Bülent Ecevit University English Preparatory School which offe...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2014.04.025
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:Poor treatment response is an important factor contributing to lack of treatment adherence. The goals of this research were to determine whether improvements in Positive and Negative Syndrome Scale (PANSS) symptom domains predict the likelihood of staying on treatment and whether differential responses to tr...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2010.12.003
更新日期:2012-01-01 00:00:00
abstract::The purpose of this study was to develop and test the Talbieh Brief Distress Inventory (TBDI), a 24-item self-report questionnaire that measures psychological distress among immigrants. The TBDI combines items from the Brief Symptom Inventory (BSI) and the Psychiatric Epidemiology Research Interview Demoralization Sca...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(95)90253-8
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to study the psychometric properties of the Social Phobia Inventory (SPIN) in its version for the context of Brazilian adults. METHODS:A sample of Brazilian university students from the general population (n = 2314) and a sample of university students identified as cases (n = 88) and...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2010.03.004
更新日期:2010-11-01 00:00:00
abstract::Prison-based research has been limited due to concern that prisoners may represent a vulnerable population secondary to possible coercion and limited capacity for voluntary informed consent. This study was designed to assess decisional capacity and susceptibility to coercion in prison research subjects. Subjects were ...
journal_title:Comprehensive psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/j.comppsych.2003.09.009
更新日期:2004-01-01 00:00:00
abstract::Combat exposure is associated with increased risk of psychiatric and substance use disorders in veterans. However, it is not known whether combat exposure independently increases risk for these disorders or whether this association is accounted for by genetic vulnerability common to posttraumatic stress disorder (PTSD...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2007.11.001
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Tonic immobility is an involuntary response to inescapable life-threatening events. Peritraumatic tonic immobility has been reported in convenience samples of female victims of sexual assault and in mixed-gender victims of different types of trauma. This study evaluated peritraumatic tonic immobility in a re...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2015.04.001
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:In exploration of the risk factors of the Chinese rural young suicide, previous researchers found low prevalence of mental problems, high degree of impulsivity, and great proportion of lethal pesticide consumption. It noticed that some of the young suicides in rural China did not intend to die from the suici...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2014.11.019
更新日期:2015-02-01 00:00:00
abstract::Clinical vignettes of patients with borderline personality disorder (BPD) and schizotypal personality disorder (STPD) were evaluated and rated for evidence of cognitive and perceptual distortions. The differences in the distortions of each group were then compared. The findings show that while STPD patients have signi...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(92)90028-o
更新日期:1992-05-01 00:00:00
abstract::The present study sought to determine concordance of cognitive impairment among elderly female twins. Cognitive testing was performed by telephone interview in a sample of 100 female-female twins older than 65 years. The participants were 32 monozygotic (MZ) and 18 dizygotic (DZ) female twin pairs, all between the age...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1053/comp.2003.50019
更新日期:2003-03-01 00:00:00
abstract:AIM:The objective of this paper is to introduce the concept of late catatonia to foreign readers for the first time in English. METHODS:The original study was conducted about 20 years ago. The subjects were 16 persons who first visited our institutions between 1990 and 1996. They fulfilled the following criteria: 1) l...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2014.07.003
更新日期:2014-10-01 00:00:00
abstract::A sample of depressed inpatients was subdivided according to their initial levels of cognitive dysfunction. These high cognitive dysfunction (HCD) patients and low cognitive dysfunction (LCD) patients received either pharmacotherapy or combined pharmacotherapy plus cognitive-behavioral psychotherapy. Treatments began ...
journal_title:Comprehensive psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/0010-440x(90)90055-w
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:Although it is well-established that juvenile offenders are at an elevated risk for depression and that, within this group, females have the highest risk, little is known regarding the trends in the prevalence of depression among juvenile offenders in the United States. In the present study, we systematically e...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2017.09.005
更新日期:2018-01-01 00:00:00
abstract::It is becoming increasingly recognized that one third to one half of children diagnosed as having attention deficit/hyperactivity disorder (ADHD) continue to exhibit symptoms of the disorder into adulthood. The nature of the clinical picture is not well understood by a substantial number of clinicians. The purpose of ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(90)90026-o
更新日期:1990-09-01 00:00:00
abstract::Phenomenological, biological, genetic, treatment-response, and outcome data support a link between schizotypal personality disorder (SPD) and schizophrenia. Furthermore, SPD and normal schizotypy also seem connected, although the relationship can at times be ambiguous. In this regard, this study was conducted to test ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(98)90073-6
更新日期:1998-05-01 00:00:00
abstract::This study measured self-reported aggression, hostility, and anger in Vietnam combat veterans with (n = 27) and without (n = 15) posttraumatic stress disorder (PTSD). On the Buss-Durkee Hostility Inventory, Past Feelings and Acts of Violence Scale, Episodic Dyscontrol Scale, and State-Trait Anger Expression Inventory ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/0010-440x(94)90278-x
更新日期:1994-09-01 00:00:00
abstract::From a total sample of 1,448 psychiatric outpatients, 175 (12.1%) received a diagnosis of a somatoform disorder according to DSM-III-R criteria. One hundred twenty-two (70%) of these patients had another current axis I diagnosis, and this rate increased to 79% (139 of 175) when lifetime psychiatric diagnoses were reco...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/s0010-440x(99)90131-1
更新日期:1999-07-01 00:00:00
abstract::People who engage in nonsuicidal self-injury (NSSI) often report high levels of impulsivity. However, results from behavioral tasks measuring impulsivity have been mixed: those with a history of NSSI generally perform comparably to healthy controls. Recent research suggests, however, that people who self-injure have s...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2016.10.011
更新日期:2017-02-01 00:00:00
abstract::The history of the positive/negative terminology, as applied to psychiatric symptoms, can be divided into an early period of original meanings, a second one of French elaboration, and the current revival. This report addresses issues concerning the meaning, referent, and nature of the link between the positive and the...
journal_title:Comprehensive psychiatry
pub_type: 历史文章,杂志文章
doi:10.1016/0010-440x(91)90016-6
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:Panic Disorder (PD) and agoraphobia (AG) are frequently comorbid with obsessive-compulsive disorder (OCD), but the correlates of these comorbidities in OCD are fairly unknown. The study aims were to: 1) estimate the prevalence of PD with or without AG (PD), AG without panic (AG) and PD and/or AG (PD/AG) in a ...
journal_title:Comprehensive psychiatry
pub_type: 杂志文章
doi:10.1016/j.comppsych.2013.11.017
更新日期:2014-04-01 00:00:00