Abstract：
PURPOSE:To discuss the presentation of localized amyloidosis affecting the nasopharynx and discuss the management options. Amyloidosis in the head and neck is a rare and benign condition that usually takes the form of localized amyloidosis. Because systemic amyloidosis markedly shortens life expectancy owing to its involvement with vital organs, rectal biopsy or fat aspiration of the anterior abdominal wall must be carried out to exclude systemic involvement. Localized amyloidosis in the head and neck can involve the orbit, sinuses, nasopharynx, oral cavity, salivary glands, and larynx. METHODS:We present the case of a patient with conductive hearing loss and serous otitis media with effusion secondary to nasopharyngeal amyloidosis, as well as present a review of the literature. RESULTS:Only a few cases of nasopharyngeal amyloidosis have thus far been reported. Patients with this disease can also present with recurrent epistaxis, postnasal drip, nasal obstruction, and eustachian tube dysfunction. Localized amyloidosis of the nasopharynx, which is slow growing, has proved difficult to treat because it can persist or recur despite surgical treatment. Furthermore, bleeding may be a major complication in treating patients with nasopharyngeal amyloidosis by transpalatal excision because the amyloid deposits cause vascular wall fragility. Finally, there is no evidence that surgical treatment of nasopharyngeal amyloidosis can prolong survival or that localized amyloidosis can progress to systemic amyloidosis. For these reasons, we elected to treat our patient with a tympanostomy tube and observation. CONCLUSION:In the absence of systemic disease, localized amyloidosis of the nasopharynx may be treated conservatively.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Patel A,Pambuccian S,Maisel Rdoi
10.1053/ajot.2002.124195subject
Has Abstractpub_date
2002-09-01 00:00:00pages
308-11issue
5eissn
0196-0709issn
1532-818Xpii
S0196070902000273journal_volume
23pub_type
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journal_title：American journal of otolaryngology
pub_type： 杂志文章
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journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1053/ajot.2002.30628
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abstract：PURPOSE:To determine the neurologic morbidity and oncologic effectiveness of carotid resection in patients with advanced squamous cell carcinoma of the head and neck. METHODS:A retrospective review of all published cases of squamous cell carcinoma of the head and neck treated by carotid resection was performed. RESUL...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,meta分析
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更新日期：2004-07-01 00:00:00
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更新日期：2014-11-01 00:00:00
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更新日期：2021-01-01 00:00:00
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journal_title：American journal of otolaryngology
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journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/0196-0709(94)90099-x
更新日期：1994-07-01 00:00:00
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更新日期：2018-01-01 00:00:00
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更新日期：2014-01-01 00:00:00
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journal_title：American journal of otolaryngology
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doi：10.1016/j.amjoto.2013.04.006
更新日期：2013-09-01 00:00:00
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pub_type： 历史文章,杂志文章
doi：10.1016/s0196-0709(80)80005-6
更新日期：1980-02-01 00:00:00
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pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章
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更新日期：2020-01-01 00:00:00
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journal_title：American journal of otolaryngology
pub_type： 杂志文章
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更新日期：1988-09-01 00:00:00
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journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2007.10.003
更新日期：2008-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-01-01 00:00:00
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journal_title：American journal of otolaryngology
pub_type： 杂志文章
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更新日期：1986-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：1981-02-01 00:00:00
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journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
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更新日期：2018-01-01 00:00:00
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journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
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更新日期：2018-01-01 00:00:00
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journal_title：American journal of otolaryngology
pub_type： 杂志文章
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更新日期：2014-03-01 00:00:00
