Alphabet soup: a personal, evolving, mostly evidence-based and logical, sequential approach to the "ABCNR" drugs in multiple sclerosis.

abstract：:There are many unique characteristics in elderly patients with epilepsy. The incidence of seizure in this age group is the highest of any age group and continues to increase as people live longer. Etiology of seizures is different than for adults and includes cerebrovascular disease, dementia, closed head injury, and ...

journal_title：Seminars in neurology

authors： Jetter GM,Cavazos JE

更新日期：2008-07-01 00:00:00

abstract：:Reported PET findings in subcortical and corticobasal degenerations, and in dystonia, are summarized in Table 3. It can be seen that, although PET is not a diagnostic technique, clinical examination combined with PET findings can help to distinguish between the various akinetic-rigid syndromes, with the proviso that p...

journal_title：Seminars in neurology

authors： Brooks DJ

更新日期：1989-12-01 00:00:00

abstract：:Arteriovenous malformations of the brain can carry considerable morbidity and mortality in the setting of rupture. The complex angioarchitecture and hemodynamic alteration requires careful consideration in diagnostic and management approaches. In this review, the authors define the pathophysiology, outline diagnostic ...

journal_title：Seminars in neurology

authors： Asif K,Leschke J,Lazzaro MA

更新日期：2013-11-01 00:00:00

abstract：:The combination of neurologic disease and ichthyosis defines a heterogeneous group of rare inherited disorders that present in infancy through early adulthood. Although affected patients share the cutaneous feature of ichthyosis, there is variability in the nature and severity of neurologic disease. Impaired cognition...

journal_title：Seminars in neurology

authors： Rizzo WB,Jenkens SM,Boucher P

更新日期：2012-02-01 00:00:00

abstract：:Listeria monocytogenes infection of the central nervous system is often not recognized and treated appropriately in the crucial early stages of the disease. Most consider patients with underlying disease or immunocompromised states to be at risk, although healthy individuals may present with a neurologic syndrome caus...

journal_title：Seminars in neurology

authors： Bartt R

更新日期：2000-01-01 00:00:00

abstract：:Benign paroxysmal positional vertigo (BPPV) is common, sometimes terrifying, but rarely portends serious disease. It is usually easily diagnosed and treated, and both the patient and the physician are immediately gratified. While much has been learned about the pathogenesis of BPPV in the past decades, many of its fea...

journal_title：Seminars in neurology

authors： Nuti D,Zee DS,Mandalà M

更新日期：2020-02-01 00:00:00

abstract：:Sleep medicine can be a particularly rewarding clinical area for neurologists. After all, the driving organ of sleep is the brain. Many of the sleep disorders are primary brain disorders, whereas other sleep disorders (and their medications) influence brain function. But without an organized approach, even the engaged...

journal_title：Seminars in neurology

authors： Ellenbogen JM

更新日期：2016-10-01 00:00:00

abstract：:Charcot-Marie-Tooth (CMT) disease is caused by mutations in several genes expressed in myelinating Schwann cells and the axons they ensheathe. Typical patients present with distally accentuated motor weakness, muscle wasting, and sensory loss leading to significant and progressive clinical morbidity and impaired quali...

journal_title：Seminars in neurology

authors： Jani-Acsadi A,Krajewski K,Shy ME

更新日期：2008-04-01 00:00:00

abstract：:Parkinsonism is a clinical syndrome, which is characterized by bradykinesia, rigidity, rest tremor, and postural instability. Idiopathic Parkinson disease (PD) is the most common cause of this syndrome, though there are several other important etiologies that must be considered. These include the atypical Parkinsonian...

journal_title：Seminars in neurology

authors： Keener AM,Bordelon YM

更新日期：2016-08-01 00:00:00

abstract：:Headache is one of the more common reasons for adults to visit an emergency department. Most of these visits are for primary headache disorders, most commonly migraine headache. The authors discuss management options for patients presenting to the emergency department with prolonged, severe, or refractory migraine hea...

journal_title：Seminars in neurology

authors： Robertson CE,Black DF,Swanson JW

更新日期：2010-04-01 00:00:00

abstract：:The field of neurocritical care has evolved tremendously in recent years, a development explained vastly by the advent of neurophysiological monitoring. From basic intracranial pressure measurements to brain tissue oxygenation, microdialysis, cerebral blood flow (CBF), and surface and intracortical electroencephalogra...

journal_title：Seminars in neurology

authors： Francoeur CL,Pain M,Mayer SA

更新日期：2016-12-01 00:00:00

abstract：:Cognitive complaints are common in any adult neurology practice, and may present in a variety of ways other than classic "memory loss." In this article, the author reviews a simple approach to a symptom-based differential diagnosis, including recognition of impairment in several key cognitive domains as well as associ...

journal_title：Seminars in neurology

authors： Woodruff BK

更新日期：2011-02-01 00:00:00

abstract：:Patients who suffer from neuromuscular diseases often have complications from respiratory insufficiencies. Some neuromuscular diseases, for example Landry Guillain-Barré syndrome, may only require temporary tracheal intubation; patients with other neuromuscular diseases, such as amyotrophic lateral sclerosis, may deci...

journal_title：Seminars in neurology

authors： Gelinas DF

更新日期：2003-03-01 00:00:00

abstract：:Calcineurin inhibitor encephalopathy (CIE) is a rare condition occurring in patients who are undergoing treatment with drugs from the calcineurin inhibitor (CI) family of immunosuppressants, either cyclosporine (CsA) or tacrolimus (TAC, FK506). Generally acute in onset, the symptoms are commonly reversible if properly...

journal_title：Seminars in neurology

authors： Mammoser A

更新日期：2012-11-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in elderly individuals. Although the diagnosis of AD requires pathological confirmation, several common clinical features of AD have been identified. These include insidious onset, gradual progression, medial temporal atrophy, temporoparietal hypoperfusion, ...

journal_title：Seminars in neurology

authors： Kramer JH,Miller BL

更新日期：2000-01-01 00:00:00

abstract：:Excessive daytime sleepiness (EDS) or somnolence is common in our patients and in society in general. The most common cause of EDS is "voluntary" sleep restriction. Other common causes include sleep-fragmenting disorders such as the obstructive sleep apnea syndrome. Somewhat less familiar to the clinician are EDS cond...

journal_title：Seminars in neurology

authors： Black JE,Brooks SN,Nishino S

更新日期：2004-09-01 00:00:00

abstract：:Dizziness, vertigo, and imbalance are likely the most common presenting complaints among patients 75 years and older in office practices. Although the cause of falls among the aging population is multifactorial, several studies have implicated senescence of the vestibular periphery. It is imperative that clinicians co...

journal_title：Seminars in neurology

authors： Ishiyama G

更新日期：2009-11-01 00:00:00

abstract：:Neurology has not typically been associated with international relief work; however, with the growth of chronic cardiovascular disease and stroke associated with unhealthy eating and sedentary ways, the appearance of "new" neurologic diseases, such as the Zika and West Nile viruses, and the high numbers of seizure dis...

journal_title：Seminars in neurology

authors： Schiess N,Saylor D,Zunt J

更新日期：2018-04-01 00:00:00

abstract：:Carotid endarterectomy is an established surgical procedure to prevent stroke. The indications, preoperative evaluation, surgical timing, technical details, complications, and special circumstances for the use of this operation are reviewed. Future developments in the surgical reconstruction of the extracranial caroti...

journal_title：Seminars in neurology

authors： Pritz MB

更新日期：1998-01-01 00:00:00

abstract：:Both general neurologists and neurologists with a broad spectrum of subspecialty interests are often asked to evaluate patients with disorders of the spinal cord. Over the past decade, there have been significant advances in our understanding of a wide spectrum of immune-mediated, infectious, metabolic, hereditary, pa...

journal_title：Seminars in neurology

authors： Kumar N

更新日期：2010-02-01 00:00:00

abstract：:Myotonic dystrophies and channelopathies are rare but important causes of muscle diseases which may present with myotonia, episodic attacks of weakness, fixed muscle weakness, and atrophy or their combination. Here, the authors provide an overview of these disorders and describe their clinical and pathophysiological f...

journal_title：Seminars in neurology

authors： Quinn C,Salajegheh MK

更新日期：2015-08-01 00:00:00

abstract：:In addition to sharing several clinical, pathologic, and molecular characteristics, many neurodegenerative disorders show extensive familial histories suggesting a substantial contribution of genetic factors to disease causation and progression. In this review, the authors provide overviews of the status of current ge...

journal_title：Seminars in neurology

authors： Lill CM,Bertram L

更新日期：2011-11-01 00:00:00

abstract：:Chronic insomnia afflicts millions of people in the United States. It is associated with decreased quality of life, accidents, several comorbid conditions, increased morbidity, and substantial direct and indirect costs. Chronic insomnia is a multifactorial and individualized disorder. Its etiology may be cognitive or ...

journal_title：Seminars in neurology

authors： Neubauer DN,Flaherty KN

更新日期：2009-09-01 00:00:00

abstract：:Rapidly progressive dementia (RPD) or cognitive decline is a common presenting complaint in neurology. While primary dementia is often a concern, other forms of reversible dementia must be thoroughly considered. This article focuses on the growing field of autoimmune encephalitis (AE) as it pertains to the differentia...

journal_title：Seminars in neurology

authors： Wesley SF,Ferguson D

更新日期：2019-04-01 00:00:00

abstract：:CPP reflects perfusion problems related to increased ICP or inadequate MAP. CPP is a most helpful and practical management tool. The relationship of CBF and CPP depends on cerebral vascular resistance (flow equals pressure divided by resistance). At present, we do not have a practical method to measure vascular resist...

journal_title：Seminars in neurology

authors： Stone JL

更新日期：1989-09-01 00:00:00

abstract：:Before the AIDS epidemic, progressive multifocal leukoencephalopathy (PML) was a rare disorder occurring most often in association with leukemia and lymphoma. Current estimates indicate that PML ultimately develops in up to 5% of all patients with AIDS. This demyelinating disease results from infection with JC virus, ...

journal_title：Seminars in neurology

authors： Berger JR,Major EO

更新日期：1999-01-01 00:00:00

abstract：:Environmental circumstances that result in ambiguity or conflict with the patterns of sensory stimulation may adversely affect the vestibular system. The effect of this conflict in sensory information may be dizziness, a sense of imbalance, nausea, and motion sickness sometimes even to seemingly minor daily head movem...

journal_title：Seminars in neurology

authors： Bronstein AM,Golding JF,Gresty MA

更新日期：2020-02-01 00:00:00

abstract：:Neuroimaging is commonly utilized in the evaluation of post-cardiac arrest patients, providing a unique ability to visualize and quantify structural brain injury that can complement clinical and electrophysiologic data. Despite its lack of validation, we would advocate that neuroimaging is a valuable prognostication t...

journal_title：Seminars in neurology

authors： Greer DM,Wu O

更新日期：2017-02-01 00:00:00

abstract：:Deficiencies in reading and writing appear to be major and lasting handicaps for learning-disabled college students. However, gains have been made in program modifications for learning-disabled students in many higher education institutions. Many adults with learning disabilities find that their handicap makes it diff...

journal_title：Seminars in neurology

authors： Gottesman RL

更新日期：1991-03-01 00:00:00

abstract：:As the population ages, the prevalence of many neurologic diseases is increasing. At the same time, older patients are undergoing more surgical procedures. This confluence of events puts neurohospitalists in a unique position to provide both pre- and postoperative guidance to minimize complications, improve clinical o...

journal_title：Seminars in neurology

authors： Hudson KA,Greene JG

更新日期：2015-12-01 00:00:00