Developmental and reactive growth of dentate gyrus afferents: cellular and molecular interactions.

abstract：:In four patients with left visuo-spatial hemineglect and right brain- damage, the therapeutic effects of Transcutaneous Electrical Nervous Stimulation (TENS) of the left neck muscles, associated with a non-specific treatment, and of a specific rehabilitation paradigm were investigated. The two treatments were given fo...

journal_title：Restorative neurology and neuroscience

authors： Pizzamiglio L,Vallar G,Magnotti L

更新日期：1996-01-01 00:00:00

abstract：:Bridging large defects in mixed nerves is still an unsolved problem in reconstructive microsurgery. Two main aspects may be distinguished: one is to obtain an appropriate substitute for the lost neural tissue, the second to direct fibers toward their previous end-organs with the highest possible specificity. In the pr...

journal_title：Restorative neurology and neuroscience

authors： Papaloïzos MY,Holmquist B,Lundborg G

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Ischemic stroke is associated with a variety pathophysiological changes affecting both glial and neuronal brain tissue. These changes are mirrored in the release of specific proteins into peripheral blood. Neurone-specific enolase (NSE), protein S100B and glial fibrillary acidic protein (GFAP) are those protein...

journal_title：Restorative neurology and neuroscience

authors： Herrmann M,Ehrenreich H

更新日期：2003-01-01 00:00:00

abstract：:Injury of the nervous system initiates a cascade of signal transduction including a rise in extracellular glutamate which leads to subsequent secondary neuronal loss. Excitotoxicity is known to play a crucial role in cell death spinal cord trauma. Gangliosides, particularly monosialogangliosides (GM1), are protective ...

journal_title：Restorative neurology and neuroscience

authors： Vorwerk CK,Bonheur J,Kreutz MR,Dreyer EB,Laev H

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Previous studies demonstrated that administering extradural cortical stimulation (ECS) to rats during the acute phase of a photothrombotic infarct enhances motor recovery. However, the effect of ECS during the subacute phase was unknown. We aimed to evaluate the effects of ECS on motor recovery in a rat model o...

journal_title：Restorative neurology and neuroscience

authors： Chang WH,Kim H,Sun W,Kim JY,Shin YI,Kim YH

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The present work compared the behavioral outcomes of ACCS therapy delivered either intravenously (i.v.) or intracerebroventricularly (i.c.v.) after penetrating ballistic-like brain injury (PBBI). Histological markers for neuroinflammation and neurodegeneration were employed to investigate the potential therapeu...

journal_title：Restorative neurology and neuroscience

authors： Deng-Bryant Y,Readnower RD,Leung LY,Cunningham TL,Shear DA,Tortella FC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The patients with chronic Disorders of Consciousness (DoC) mostly present with extremely challenging differential diagnosis. The advanced analysis of electroencephalographic (EEG) signals induced by brain stimulation paradigms may provide an appropriate approach to differentiate patients with DoC, besides th...

journal_title：Restorative neurology and neuroscience

authors： Naro A,Leo A,Bruno R,Cannavò A,Buda A,Manuli A,Bramanti A,Bramanti P,Calabrò RS

更新日期：2017-01-01 00:00:00

abstract：:Portions of 1 cm length of the sensory radial nerve from the cat forelimb were used to replace an excised portion of the dorsal columns in the upper lumbar spinal cord. Observations were made on the clinical recovery of the animals, and cine recordings were made of their ability to traverse a horizontal ladder 5 month...

journal_title：Restorative neurology and neuroscience

authors： Wilson DH

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Dimethyl fumarate (DMF) has immune-modulatory and neuro-protective characteristics that can be used for treatment of acute ischemic stroke. OBJECTIVE:To investigate the therapeutic effects of DMF on histological and functional recovery of rats after transient middle cerebral artery (MCA) occlusion. METHODS...

journal_title：Restorative neurology and neuroscience

authors： Safari A,Fazeli M,Namavar MR,Tanideh N,Jafari P,Borhani-Haghighi A

更新日期：2017-01-01 00:00:00

abstract：:Purpose: Damage of primary visual cortex in adult humans, monkeys and cats severely disrupts vision by disconnecting much of the cogni-tive processing machinery of extrastriate cortex from its source of visual signals in the retina. Equivalent lesions sustained early in life result in partial sparing of visual process...

journal_title：Restorative neurology and neuroscience

authors： Payne BR,Lomber SG

更新日期：2000-01-01 00:00:00

abstract：:The outgrowth of neurites in neuronal cell cultures reflects the intrinsic capacity for neurite regeneration and morphological rearrangements after axotomy and in plasticity. The role of fast axonal transport in these neurite outgrowth responses has not been investigated. We have recently shown that sabeluzole (R58735...

journal_title：Restorative neurology and neuroscience

authors： Geerts H,Nuydens R,Nuyens R,Cornelissen F

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The current treatment intervention study determined the effect of coupled bilateral training (i.e., bilateral movements and EMG-triggered neuromuscular stimulation) and resistive load (mass) on upper extremity motor recovery in chronic stroke. METHODS:Thirty chronic stroke subjects were randomly assigned to...

journal_title：Restorative neurology and neuroscience

authors： Cauraugh JH,Coombes SA,Lodha N,Naik SK,Summers JJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Oxidative stress is an important factor in the pathophysiologic changes after traumatic brain injury (TBI). Connexin43 (Cx43) was reported to contribute to cerebral damage. However, the impacts of Cx40 have not been investigated in detail. OBJECTIVE:In the present study, we hypothesized that Cx40 was involv...

journal_title：Restorative neurology and neuroscience

authors： Chen W,Guo Y,Yang W,Zheng P,Zeng J,Tong W

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Multiple Sclerosis is a heterogeneous disorders involving in early stage gait and balance. Together with immunomodulating therapies, rehabilitation had a crucial role in improving motor tasks and quality of life. Between the emerging techniques, Focal Vibrations (FV) could play a role, but they have been use...

journal_title：Restorative neurology and neuroscience

authors： Spina E,Carotenuto A,Aceto MG,Cerillo I,Silvestre F,Arace F,Paone P,Orefice G,Iodice R

更新日期：2016-09-21 00:00:00

abstract：:The brain can undergo self-repair and has the ability to compensate for functions lost after a stroke. The plasticity of the ischemic brain is influenced by several factors including aging and pharmacotherapy. Fluoxetine is an antidepressant which enhances serotonergic neurotransmission through selective inhibition of...

journal_title：Restorative neurology and neuroscience

authors： Sun Y,Sun X,Qu H,Zhao S,Xiao T,Zhao C

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To investigate whether repeated sessions of motor imagery and action observation modulate corticospinal excitability (CE) over time, whether these processes are susceptible of any training effect and if such effect might be different for the dominant and non dominant hemisphere. METHODS:11 subjects underwent t...

journal_title：Restorative neurology and neuroscience

authors： Bianco G,Feurra M,Fadiga L,Rossi A,Rossi S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Immunomodulatory agents are often combined in organ transplantation to minimize toxicity and enhance therapeutic effect. We hypothesized that combining low-dose FK506 with anti-CD40 Ligand (anti-CD40L mAb) would enhance regeneration through peripheral nerve allografts while preserving immune unresponsiveness. ...

journal_title：Restorative neurology and neuroscience

authors： Brenner MJ,Mackinnon SE,Rickman SR,Jaramillo A,Tung TH,Hunter DA,Mohanakumar T

更新日期：2005-01-01 00:00:00

abstract：:Various basic qualitative and quantitative methods for the evaluation of sensorimotor functions after Traumatic Brain Injury (TBI) are introduced and discussed. Methodological aspects are illustrated by a single case follow-up study of a child after severe TBI (age 11; 7–12;1 yrs; 6, 8 and 12 month post TBI) in compar...

journal_title：Restorative neurology and neuroscience

authors： Jöhnk K,Kuhtz-Buschbeck JP,Stolze H,Serocki G,Kalwa S,Ritz A,Benz B,Illert M

更新日期：1999-01-01 00:00:00

abstract：:While the regenerating capacity of peripheral nerves has been the subject of intensive study, little is known about the regenerative capacity of the autonomic nervous system. Using an animal model, where the pupil diameter of the eye in the rat serves as a parameter of autonomic function, we studied whether systemic t...

journal_title：Restorative neurology and neuroscience

authors： Vandertop WP,de Vries WB,Notermans NC,Tulleken CA,Gispen WH

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Robot-assisted gait training (RAGT) is widely used in children with cerebral palsy (CP), but information about optimal intervention frequency and duration is still lacking and the current evidence about effect of RAGT on motor endurance and fitness is very preliminary. OBJECTIVE:To investigate the effect of...

journal_title：Restorative neurology and neuroscience

authors： Digiacomo F,Tamburin S,Tebaldi S,Pezzani M,Tagliafierro M,Casale R,Bartolo M

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:Transgenic manipulation of mouse physiology facilitates the preclinical study of genetic risk factors, neural plasticity, and reactive processes accompanying Alzheimer's disease. Alternatively, entorhinal cortex lesions (ECLs) model pathophysiological denervation and axonal sprouting in rat. Given reports of an...

journal_title：Restorative neurology and neuroscience

authors： Feeney EJ,Stephenson D,Kleiman R,Bove S,Cron C,Moody L,Robinson M,Ramirez JJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Low-frequency rTMS can induce upregulation of excitability in the contralateral hemisphere by interhemispheric interaction. OBJECTIVE:The aim of this study was to compare the effects of interhemispheric modulation on hemodynamic changes after applying low-frequency rTMS over the anatomical hand knob (HK) an...

journal_title：Restorative neurology and neuroscience

authors： Kim J,Kim H,Lee J,Lee HJ,Na Y,Chang WH,Kim YH

更新日期：2020-01-01 00:00:00

abstract：:In the present study, we have developed an animal model for central nervous system (CNS) damage using the graded crush injury of the adult rat optic nerve. This injury model has the following characteristics: (a) the injuries are reproducible; (b) the injuries can be created with controlled severity; and (c) variation...

journal_title：Restorative neurology and neuroscience

authors： Duvdevani R,Rosner M,Belkin M,Sautter J,Sabel BA,Schwartz M

更新日期：1990-01-01 00:00:00

abstract：:To examine the regeneration capacity of dorsal septohippocampal neurons in the presence of an artificial growth-promoting substrate, biocompatible polymeric hydrogels were implanted between the septum and the hippocampus in a fimbria-fornix lesion cavity. Unmodified (control) or aminosugar-containing (glucosamines or ...

journal_title：Restorative neurology and neuroscience

authors： Duconseille E,Woerly S,Kelche C,Will B,Cassel JC

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Progressive apoptosis in the dopaminergic neurons of substantia nigra lead to Parkinson's disease. Since neurons require substantially higher supply of energy, their mitochondria have a pivotal status in neuronal survival. These organelles have a key role to play in apoptosis and any impairment thereof may l...

journal_title：Restorative neurology and neuroscience

authors： Qadri R,Namdeo M,Behari M,Goyal V,Sharma S,Mukhopadhyay AK

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To investigate the effects of the androgen testosterone propionate (TP), on regeneration of the recurrent laryngeal nerve (RLN) after unilateral crush injury using assessment of vocal fold mobility (VFM) as a measure of behavioral recovery. METHODS:48 adult male rats underwent standardized crush injury of left...

journal_title：Restorative neurology and neuroscience

authors： Brown TJ,Pittman AL,Monaco GN,Benscoter BJ,Mantravadi AV,Akst LM,Jones KJ,Foecking EM

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The effectiveness of embryonic stem cell (eSC) therapy has been explored in many models of neurological disease and several research groups have shown that eSC treatment leads to improved outcomes in pre-clinical models of traumatic brain injury (TBI). Though functional recovery occurs, few surviving eSCs appea...

journal_title：Restorative neurology and neuroscience

authors： Peruzzaro ST,Gallagher J,Dunkerson J,Fluharty S,Mudd D,Hoane MR,Smith JS

更新日期：2013-01-01 00:00:00

abstract：:Embryonic stem (ES) cells have the ability to differentiate into a variety of cell lineages. We are examining ES cell differentiation in vitro by using cDNA microarrays to generate a molecular phenotype for each cell type. El4 ES cells induced by retinoic acid after forming embryoid bodies differentiate almost exclusi...

journal_title：Restorative neurology and neuroscience

authors： Loring JF,Porter JG,Seilhammer J,Kaser MR,Wesselschmidt R

更新日期：2001-01-01 00:00:00

abstract：:Psychopathy is a mental disorder marked by deficient emotional responses, lack of empathy, and poor behavioral controls, commonly resulting in persistent antisocial deviance and criminal behavior. Accumulating research suggests that psychopathy follows a developmental trajectory with strong genetic influences, and whi...

journal_title：Restorative neurology and neuroscience

authors： Anderson NE,Kiehl KA

更新日期：2014-01-01 00:00:00

abstract：:It is widely accepted that the suprachiasmatic nuclei (SCN) of the hypothalamus serve as biological pacemakers, organizing daily activities. However some circadian rhythms are controlled by extra-SCN structures. Transplantation of fetal donor SCN in SCN-lesioned rodents induces recovery of rhythmic locomotor and drink...

journal_title：Restorative neurology and neuroscience

authors： Le Sauter J,Silver R

更新日期：1994-01-01 00:00:00