Stages of the rat thymic medulla development in foetal period.

Abstract:

:Development of thymic medulla was examined on consecutive gestational days (GD) in Wistar rats. Medullary thymic epithelial cells (TEC) were identified by immunocytochemical localisation of neuron-specific enolase (NSE). Organisation of thymic medullary architecture was determined by interaction of thymocytes with NSE-positive TEC, that led to formation of lymphoepithelial complexes (GD 19), in which the cells exhibited proliferative activity or traits of apoptosis. The studies indicated that differentiation events and organisation of thymic medulla require stage-specific interactions between TEC and thymocytes.

authors

Brelińska R,Ostalska D,Kaczmarek E,Kowalska K

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

171-2

issue

2

eissn

0239-8508

issn

1897-5631

journal_volume

40

pub_type

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