Abstract：
:The effects of stereotype suppression on psychiatric stigma were investigated in two studies. In experiment 1, 52 participants were presented with a photograph of someone labeled with schizophrenia and instructed to write a passage describing a day in that person's life. Half of the participants were instructed to avoid using schizophrenia-related stereotypes in their passages (the stereotype suppression condition). Participants were then presented with a photograph of a different individual labeled with schizophrenia and asked to write another passage with stereotype suppression instructions omitted. The results showed that while stereotype suppression occurred for the first passage, the expected rebound effects were not observed in the second passage. Furthermore, the results were unchanged when participants' prior experience with persons with mental illness was considered. In a second study, the effects of stereotype suppression on behavior (i.e. seating distance from a person with schizophrenia) were examined in 58 participants. While the stereotype suppression instructions resulted in less stereotypical passages, replicating the results of study 1, no rebound effects on behavior were observed. A non-significant trend was observed whereby previous contact with persons with mental illness was associated with less social distance from someone with schizophrenia. Implications of the findings for reducing psychiatric stigma are discussed.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Penn DL,Corrigan PWdoi
10.1016/s0920-9964(01)00207-9subject
Has Abstractpub_date
2002-06-01 00:00:00pages
269-76issue
3eissn
0920-9964issn
1573-2509pii
S0920996401002079journal_volume
55pub_type
临床试验,杂志文章,随机对照试验abstract：:Affect perception has frequently been shown to be impaired in patients suffering from schizophrenia or bipolar disorder (BD), but it remains unclear whether these impairments exist during symptomatic remission and whether the two disorders differ from each other in this regard. Most previous studies have investigated ...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.07.019
更新日期：2014-09-01 00:00:00
abstract：:This study was a preliminary open clinical trial aimed at exploring the hypothesis that estrogen may provide protection against schizophrenia in women. Eleven women with acute psychotic symptoms, as scored on the BPRS, SAPS and SANS, had 0.02 mg estradiol added to neuroleptic treatment for eight weeks. Their response ...
journal_title：Schizophrenia research
pub_type： 临床试验,杂志文章
doi：10.1016/0920-9964(96)82949-5
更新日期：1996-07-05 00:00:00
abstract：:Dopamine's proposed role in psychosis proved a starting point in our understanding of the neurobiology of relapse, fitting given the central role positive symptoms play. This link is reflected in early work examining neurotransmitter metabolite and drug (e.g. amphetamine, methylphenidate) challenge studies as a means ...
journal_title：Schizophrenia research
pub_type： 杂志文章,评审
doi：10.1016/j.schres.2013.10.009
更新日期：2014-02-01 00:00:00
abstract：:Nondeclarative memory (NDM) has subtypes associated with different brain regions; learning of a probabilistic classification task is impaired by striatal damage and learning of a gambling task is impaired by ventromedial prefrontocortical damage. Typical and atypical antipsychotic medications differentially affect imm...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(02)00315-8
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Negative symptoms in schizophrenia are associated with deficits in executive function and frequently prove highly resistant to neuroleptic medication. Using repetitive transcranial magnetic stimulation (rTMS) to activate the prefrontal cortex has been suggested as a treatment for negative symptoms. METHODS:...
journal_title：Schizophrenia research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.schres.2007.03.016
更新日期：2007-07-01 00:00:00
abstract：:The involvement of the gamma-aminobutyric acid (GABA) system in schizophrenia is suggested by postmortem studies and the common use of GABA receptor-potentiating agents in treatment. In a recent study, we used a benzodiazepine challenge to demonstrate abnormal GABAergic function during processing of negative visual st...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.08.022
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Family studies have suggested that schizophrenia and bipolar disorders share some susceptibility factors. Schizotypal personality disorder (SPD) may be an intermediate phenotype common both to schizophrenia and bipolar disorders. We explored the familiality of schizotypal dimensions by comparing the magnitud...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2005.07.009
更新日期：2005-12-15 00:00:00
abstract：:Evidence suggests that insight in psychosis has been related to treatment adherence, recovery and good prognosis, but also to depression, low self-esteem, and diminished quality of life. Thus, insight might not be advantageous under all circumstances. Internalized-stigma (i.e. self-acceptance of stigmatizing images of...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.03.010
更新日期：2015-05-01 00:00:00
abstract：:Recent research conducted in high-income countries suggests psychotic experiences are common in the general population, but evidence from low- and middle-income countries (LMIC) remains limited. Sri Lanka is a LMIC affected by three decades of civil conflict and, in 2004, a devastating tsunami. This study aimed to inv...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.01.026
更新日期：2016-03-01 00:00:00
abstract：INTRODUCTION:Dysfunctional serotonin signaling has been linked to the pathogenesis of autism, obsessive compulsive disorder, mood disorders and schizophrenia. While the hypo-activity of serotonin signaling is involved in the pathogenesis of depression, anxiety and obsessive compulsive disorder; LSD, an agonist of serot...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2013.12.007
更新日期：2014-02-01 00:00:00
abstract：:Auditory-verbal hallucinations (AVHs) are associated with an impaired connectivity of large-scale networks. To examine the relationship between white-matter integrity and AVHs, we conducted a meta-analysis of diffusion-tensor-imaging studies that compared patients with schizophrenia and AVHs with matched healthy contr...
journal_title：Schizophrenia research
pub_type： 杂志文章,meta分析
doi：10.1016/j.schres.2014.07.014
更新日期：2014-10-01 00:00:00
abstract：:Previous studies have demonstrated that patients with schizophrenia and individuals with schizotypy experience decreased anticipatory pleasure. However, it is unclear whether this decrease is contributed by altered reward processing at the proximal or distal future. In order to investigate the preference for receiving...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2018.12.040
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:There is increased interest in the impact of new long-acting treatments on health-related quality of life (HRQoL) in patients with schizophrenia. The aim of this study was to evaluate the impact of treatment with subcutaneous injections of RBP-7000, a new sustained-release formulation of risperidone, compare...
journal_title：Schizophrenia research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.schres.2016.03.020
更新日期：2016-07-01 00:00:00
abstract：:The ubiquitin ligase F-box protein 45 (FBXO45) is critical for synaptogenesis, neuronal migration, and synaptic transmission. FBXO45 is included in the 3q29 microdeletion region that confers a significant risk for schizophrenia, as shown by rare structural variant studies. Thus, FBXO45 is considered a prominent candid...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.04.032
更新日期：2014-08-01 00:00:00
abstract：:This study documents a severe picture naming impairment in a series of 22 chronically hospitalised schizophrenics. The pattern and level of naming impairment were comparable in degree and type to that seen neurological patients with left hemisphere lesions. This deficit was further examined to determine whether it con...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(99)00184-x
更新日期：2000-09-29 00:00:00
abstract：BACKGROUND:Patients with schizophrenia show deviances in their dermatoglyphics, in particular reductions in palmar a-b ridge counts (ABRCs), which are evidence of an early developmental deviance. However, the severity or the origin of these ABRC changes has not been established. METHOD:(i) We examined the published li...
journal_title：Schizophrenia research
pub_type： 杂志文章,meta分析
doi：10.1016/j.schres.2004.08.022
更新日期：2005-06-15 00:00:00
abstract：:Accumulating evidence showed that interleukin-2 (IL-2) may be involved in the pathophysiology of schizophrenia. Increased IL-2 levels have been found in the serum of schizophrenia patients with mixed results. In the present study, we assessed serum IL-2 levels in a large group of 160 schizophrenia patients compared to...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.10.038
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Current early screeners for psychosis-risk states have still to prove ability in identifying at-risk individuals. Among screeners, the 92-item Prodromal Questionnaire (PQ-92) is often used. We aimed to assess the validity of its Italian translation in a large Italian adolescent and young adult help-seeking s...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2017.02.008
更新日期：2017-11-01 00:00:00
abstract：:Mismatch negativity (MMN) and P3a are auditory event-related potential (ERP) components that show robust deficits in schizophrenia (SZ) patients and exhibit qualities of endophenotypes, including substantial heritability, test-retest reliability, and trait-like stability. These measures also fulfill criteria for use a...
journal_title：Schizophrenia research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.schres.2014.09.042
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:cortical gray matter volume deficit and ventricular enlargement are well documented in schizophrenia, but their presence in bipolar disorder is less well established. METHODS:global cortical gray matter, white matter and sulcal CSF, as well as lateral and third ventricular volume measures, were derived from...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(99)00063-8
更新日期：1999-12-21 00:00:00
abstract：:An accumulating body of literature supports the notion that psychotic-like experiences (PLEs) may occur as a continuous phenotype. However, researchers are still working to determine if these events accompany an underlying continuum of neurobiological vulnerability as well. Within this context, it is notable that spon...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2011.06.028
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Accurately diagnosing schizophrenia is still challenging due to the lack of validated biomarkers. Here, we aimed to investigate whether radiomic features in bilateral hippocampal subfields from magnetic resonance images (MRIs) can differentiate patients with schizophrenia from healthy controls (HCs). METHOD...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2020.09.009
更新日期：2020-09-01 00:00:00
abstract：:Arinami et al. (1994) reported an association between the Ser311/Cys311 variant of the DRD2 gene and schizophrenia in a Japanese population. We did not find statistically significant differences in the distribution of the allele frequencies between schizophrenics (103) and controls (97) in a case-control sample (chi 2...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/S0920-9964(97)00013-3
更新日期：1997-05-24 00:00:00
abstract：:Primary motor abnormalities (PMA), as found in patients with schizophrenia, are quantitatively and qualitatively distinct markers of motor system abnormalities. PMA have been often referred to phenomena that are present across schizophrenia-spectrum disorders. A dysfunction of frontoparietal and subcortical networks h...
journal_title：Schizophrenia research
pub_type： 杂志文章,评审
doi：10.1016/j.schres.2017.10.007
更新日期：2018-10-01 00:00:00
abstract：INTRODUCTION:Emotion perception (EP) is impaired in schizophrenia, is stable across clinical state, resistant to antipsychotic treatment and linked to symptom severity. Given its pervasive nature, there is a need to quantitatively examine whether this dysfunction impacts functional outcomes. We used a meta-analytic str...
journal_title：Schizophrenia research
pub_type： 杂志文章,meta分析
doi：10.1016/j.schres.2012.01.023
更新日期：2012-05-01 00:00:00
abstract：:Attention Deficit/Hyperactivity Disorder (ADHD) is the most common psychiatric disorder in childhood. It is unclear whether ADHD increases the risk of non-affective psychotic disorder (NAPD). The study included a matched cohort, drawn from all born in Sweden 1987-1991 (n = 548,852). ADHD was defined as ICD diagnosis a...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2020.01.021
更新日期：2020-04-01 00:00:00
abstract：:The degree of cortical atrophy as revealed by computed tomographic scans was assessed in 124 patients meeting the DSM III criteria for schizophrenia and in 45 age- and sex-matched healthy controls. 21 patients, i.e., 33% of the entire sample, showed moderate to severe atrophy. The presence of atrophy was not associate...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/0920-9964(88)90046-1
更新日期：1988-09-01 00:00:00
abstract：:Developmental instability (DI) refers to the inability of the developing brain to buffer the effects of genetic and environmental insults. This concept has been invoked to better understand how fetal brain development goes awry in schizophrenia and related spectrum disorders. This study examined one marker of DI, mino...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2009.10.028
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:Individuals with both physical and mental health problems may have elevated levels of emergency department (ED) service utilization either for index conditions or for associated comorbidities. This study examines the use of ED services by Medicaid beneficiaries with comorbid diabetes and schizophrenia, a dyad...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2013.12.002
更新日期：2014-02-01 00:00:00
abstract：:Schizophrenia is modelled as a neurodevelopmental disease with high heritability. However, established markers like cortical thickness and grey matter volume are heavily influenced by post-onset changes and thus provide limited possibility of accessing early pathologies. Gyrification on the other side is assumed to be...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2018.07.014
更新日期：2018-12-01 00:00:00
