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The Arcuate Fasciculus in auditory-verbal hallucinations: a meta-analysis of diffusion-tensor-imaging studies.

Abstract：

:Auditory-verbal hallucinations (AVHs) are associated with an impaired connectivity of large-scale networks. To examine the relationship between white-matter integrity and AVHs, we conducted a meta-analysis of diffusion-tensor-imaging studies that compared patients with schizophrenia and AVHs with matched healthy controls (HCs). Five studies were retained gathering 256 DTI data points, divided into AVHs (n=106) and HCs (n=150). The meta-analysis demonstrated a reduced fractional anisotropy in the left Arcuate Fasciculus (AF) of hallucinators (hg= -0.42; CI[-0.69,-0.16]; p<10(-3)). The current meta-analysis confirmed disruptions of white matter integrity in the left AF bundle of schizophrenia patients with AVHs.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Geoffroy PA,Houenou J,Duhamel A,Amad A,De Weijer AD,Curčić-Blake B,Linden DE,Thomas P,Jardri R

doi

10.1016/j.schres.2014.07.014

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

234-7

issue

1

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(14)00371-5

journal_volume

159

pub_type

杂志文章,meta分析

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