Bile acid excretion after pull-through operation for Hirschsprung's disease.

Abstract:

:Four children with chronic diarrhoea and perianal excoriation after a pull-through operation for Hirschsprung's disease have been shown to have increased but not markedly raised levels of faecal bile acids. Bile acid analysis of the 'bile-rich' duodenal fluid obtained after pancreozymin stimulation in 3 of the patients indicated a marked reduction in the proportion of deoxycholic acid conjugates. These findings are compatible with colonic malabsorption of secondary bile acids in these patients which is related in some way to the pull-through operation, but which is not likely to be the cause of the diarrhoea and the anal excoriation.

journal_name

Arch Dis Child

authors

Gaze H,Murphy GM,Nelson R,Corkery JJ,Anderson CM

doi

10.1136/adc.50.3.243

subject

Has Abstract

pub_date

1975-03-01 00:00:00

pages

243-5

issue

3

eissn

0003-9888

issn

1468-2044

journal_volume

50

pub_type

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