Abstract:
AIMS:To examine short term and long term health related quality of life (HRQoL) of survivors of congenital anorectal malformations (ARM) and congenital diaphragmatic hernia (CDH), and to compare these patients' HRQoL with that of the general population. METHODS:HRQoL was measured in 286 ARM patients and 111 CDH patients. All patients were administered a symptom checklist and a generic HRQoL measure. For the youngest children (aged 1-4) the TAIQOL (a preliminary version of the TAPQOL) was used, for the other children (aged 5-15) the TACQOL questionnaire, and for adults (aged >16) the SF-36. RESULTS:As appeared from the symptom checklists, many patients remained symptomatic into adulthood. In the youngest ARM patients (aged 1-4 years), generic HRQoL was severely affected, but the older ARM patients showed better HRQoL. In the CDH patients, the influence of symptoms on HRQoL seemed less profound. The instruments we used revealed little difference between adults treated for ARM or CDH and the general population. CONCLUSIONS:These results show that for two neonatal surgical procedures, improved survival does not come at the expense of poor HRQoL in adults. Even though there is considerable suffering in terms of both morbidity and mortality in the youngest group, the ultimate prognosis of survivors of the two studied congenital malformations is favourable. This finding can be used to reassure parents of patients in need of neonatal surgery for one of these conditions about the prospects for their child.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Poley MJ,Stolk EA,Tibboel D,Molenaar JC,Busschbach JJdoi
10.1136/adc.2002.016543subject
Has Abstractpub_date
2004-09-01 00:00:00pages
836-41issue
9eissn
0003-9888issn
1468-2044pii
89/9/836journal_volume
89pub_type
杂志文章abstract:OBJECTIVES:To understand the experiences and perceptions of healthcare services of children with life-limiting and life-threatening conditions and their family members, including palliative care. DESIGN:Longitudinal qualitative interview study with children and their family members. Up to three in-depth interviews wer...
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abstract::Idiopathic pulmonary haemosiderosis is a very rare but devastating disorder. Diagnosis is sometimes difficult and the clinical course exceedingly variable, as illustrated by this report of a girl, aged 2 years 4 months, with severe iron deficiency anaemia. There was no response to iron therapy and transfusions. Sustai...
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doi:10.1136/adc.66.9.1047
更新日期:1991-09-01 00:00:00
abstract::A 12 year old Asian girl with a four year history of poorly controlled insulin dependent diabetes mellitus developed overt diabetic nephropathy. There were no clinical features of Rabson-Mendenhall syndrome. Screening for microalbuminuria would have identified incipient diabetic nephropathy and highlighted the importa...
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更新日期:1997-12-01 00:00:00
abstract::A postal survey of recently appointed consultant paediatricians was undertaken to determine whether they perceived their training had adequately equipped them for their current job. The response rate was 69% (207/299). After excluding replies from consultants trained outside the UK the analysis was carried out on 167 ...
journal_title:Archives of disease in childhood
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更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:The management of subclinical hypothyroidism (SH) is still controversial, as the benefit to risk ratio of prolonged L-thyroxine therapy is not clear cut. Some authors have shown abnormalities of myocardial function and structure in adults with SH, which could be reversed by L-thyroxine therapy. As SH frequen...
journal_title:Archives of disease in childhood
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更新日期:2003-11-01 00:00:00
abstract:AIMS:To determine whether delayed capillary refill time (>3 seconds) is a useful prognostic indicator in Kenyan children admitted to hospital. METHODS:A total of 4160 children admitted to Kilifi District Hospital with malaria, malarial anaemia, acute respiratory tract infection (ARI), severe anaemia (haemoglobin <50 g...
journal_title:Archives of disease in childhood
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doi:10.1136/adc.2003.032516
更新日期:2004-10-01 00:00:00
abstract::Reverse triiodothyronine (rT3), triiodothyronine (T3), thyroxine (T4), and thyroid stimulating hormone (TSH) values were measured by radioimmunoassay in 40 children with congenital hypothyroidism who were being given levothyroxine (0.05-0.35 mg/day) and in 14 normal controls. In 15 of the children with hypothyroidism ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.1.30
更新日期:1984-01-01 00:00:00
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更新日期:2000-11-01 00:00:00
abstract::The risk factors for mortality were analysed in a consecutive group of 1158 children presenting to the Aga Khan University Medical Center, Karachi, with multidrug resistant typhoid fever that had been proved on culture. There were 19 deaths, representing an overall case fatality rate of 1.6%. Multidrug resistant typho...
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1986-07-01 00:00:00
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journal_title:Archives of disease in childhood
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更新日期:1978-02-01 00:00:00
abstract:OBJECTIVE:Most babies receive at least some formula milk. Variations in formula-feeding practices can have both short- and long-term health consequences. The literature on parents' experiences of bottle-feeding was systematically reviewed to understand how formula-feeding decisions are made. METHODS:Relevant English-l...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
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更新日期:2009-08-01 00:00:00
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journal_title:Archives of disease in childhood
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更新日期:1989-07-01 00:00:00
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journal_title:Archives of disease in childhood
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更新日期:1988-07-01 00:00:00
abstract::Two Japanese outbreaks of erythema infectiosum were investigated for evidence of human parvovirus infection by a solid phase antibody capture radioimmunoassay based on a monoclonal antibody to human parvovirus. Specific IgM and high concentrations of specific IgG were detected in 37 sera from 27 children with erythema...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.11.1016
更新日期:1984-11-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2009.180125
更新日期:2011-03-01 00:00:00
abstract::In a multicentre study on perinatal HIV-I infection including 1493 children born from 1471 pregnancies to 1415 infected mothers, 22 twin pairs and 56 sibships (115 children) were recorded. The frequency of twin pregnancies was 1.5 (22/1471) and 3.9% (56/1415) seropositive women had more than one at risk pregnancy. In ...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1136/adc.66.10.1235
更新日期:1991-10-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1997-02-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1995-04-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.6.575
更新日期:1984-06-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.53.3.210
更新日期:1978-03-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1984-08-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1982-03-01 00:00:00
abstract:AIMS:To describe the epidemiology of children with traumatic brain injury (TBI) admitted to paediatric intensive care units (PICUs) in the UK. METHODS:Prospective collection of clinical and demographic information from paediatric and adult intensive care units in the UK and Eire between February 2001 and August 2003. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
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更新日期:2005-11-01 00:00:00
abstract::Significant folate deficiency in 14 out of 37 preterm infants of birthweights 2.0 kg or less was found to be reliably and most conveniently diagnosed by abnormal morphological changes in peripheral blood and confirmed by the response to folic acid. Deficiency appeared to be more common in light-for-dates infants inclu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.4.271
更新日期:1979-04-01 00:00:00
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journal_title:Archives of disease in childhood
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更新日期:1999-05-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1980-06-01 00:00:00
abstract::Flow velocities in the basal cerebral arteries were studied by transcranial Doppler sonography. A longitudinal study was undertaken on 25 healthy newborn babies during the first 20 days of life, and a cross sectional study was performed on 112 healthy children between 1 day and 18 years of age. A rapid linear increase...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.63.6.606
更新日期:1988-06-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/archdischild-2016-310594
更新日期:2017-04-01 00:00:00