Abstract:
:Although several authors have reported single cases illustrative of some ultrasonographic characteristic of parathyroid carcinoma, the value of ultrasonography for diagnosing this entity remains to be determined. The purpose of our study was to investigate the ultrasonographic features of parathyroid carcinoma in a large number of cases. We assessed the shape, contour, echogenicity, and depth-width (DW) ratio of 16 parathyroid carcinomas and 61 parathyroid adenomas. Ultrasonography showed that parathyroid carcinomas tend to be large, inhomogeneous, hypoechoic masses with lobulated contours. In contrast, parathyroid adenomas were small, homogeneous, hypoechoic masses with smooth borders. The mean (range) DW ratios for parathyroid carcinomas were 1.21 (0.91-2.5) and 0.64 (0.33-1.47) for adenomas; the difference was statistically significant (p<0.0001). The DW ratio was > or =1 in 15 (94%) of the 16 cases of carcinoma, whereas only 3 (5%) of the 61 adenomas had a similar ratio. Ultrasonographic examination is useful not only for preoperative localization but also for differentiating parathyroid carcinoma from adenoma. Parathyroid tumors with irregular margins, inhomogeneous echogenicity, and a DW ratio > or =1 are likely to be malignant.
journal_name
Endocr Jjournal_title
Endocrine journalauthors
Hara H,Igarashi A,Yano Y,Yashiro T,Ueno E,Aiyoshi Y,Ito K,Obara Tdoi
10.1507/endocrj.48.213subject
Has Abstractpub_date
2001-04-01 00:00:00pages
213-7issue
2eissn
0918-8959issn
1348-4540journal_volume
48pub_type
杂志文章abstract::Triptolide, a major active component of Tripterygium wilfordii Hook F (TWHF), is known to have multiple pharmacological activities. However, studies have also shown that triptolide is highly toxic to the reproductive system by disrupting normal androgen and estrogen signaling. In the present study, we investigated the...
journal_title:Endocrine journal
pub_type: 杂志文章
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abstract::Lipopolysaccharide (LPS) is known to stimulate the synthesis and secretion of various proinflammatory cytokines in both the peripheral immune cells and the brain. Yet, the relative contribution of peripheral and central cytokines to the LPS-induced activation of the hypothalamo-pituitary-adrenal axis is still poorly u...
journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.46.487
更新日期:1999-08-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.50.61
更新日期:2003-02-01 00:00:00
abstract::Diabetic foot ulcer is a chronic, refractory, frequent complication in diabetic patient. Its treatment often requires multidisciplinary joint efforts, diverse strategies have been adopted to address this annoying issue, including stem cell-based therapy/acellular dermal matrix/negative pressure wound therapy etc. Howe...
journal_title:Endocrine journal
pub_type: 杂志文章,meta分析
doi:10.1507/endocrj.EJ17-0424
更新日期:2018-04-26 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章,随机对照试验
doi:10.1507/endocrj.k09e-147
更新日期:2009-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
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journal_title:Endocrine journal
pub_type: 临床试验,杂志文章
doi:10.1507/endocrj.50.545
更新日期:2003-10-01 00:00:00
abstract::Glucocorticoids play a critical role in the regulation of homeostasis, including metabolism. In patients with Cushing's syndrome, chronic glucocorticoid excess disrupts physiological internal milieu, resulting in central obesity, muscle atrophy, fatty liver, and insulin resistance. However, the relationship among vari...
journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.EJ19-0205
更新日期:2020-01-28 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.EJ20-0171
更新日期:2020-12-28 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.ej11-0234
更新日期:2012-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.ej12-0293
更新日期:2013-01-01 00:00:00
abstract::Unusual presentations with bone, lung or soft tissue metastases in initial diagnosis of follicular thyroid carcinoma have been reported occasionally. This implies how difficult it is to diagnosis this type of cancer at the pre-operative or intra-operative stage of treatment. Fine needle aspiration cytology has been sh...
journal_title:Endocrine journal
pub_type: 杂志文章,评审
doi:10.1507/endocrj.kr-77
更新日期:2006-08-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.46.723
更新日期:1999-10-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.45.427
更新日期:1998-06-01 00:00:00
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journal_title:Endocrine journal
pub_type: 临床试验,杂志文章
doi:10.1507/endocrj.47.517
更新日期:2000-10-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.k10e-251
更新日期:2011-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.ej13-0270
更新日期:2013-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章,评审
doi:10.1507/endocrj.k10e-150
更新日期:2010-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
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更新日期:1998-04-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.k10e-231
更新日期:2010-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-10-28 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.40.705
更新日期:1993-12-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.EJ20-0213
更新日期:2020-11-28 00:00:00
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journal_title:Endocrine journal
pub_type: 临床试验,杂志文章
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更新日期:1997-08-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.46.263
更新日期:1999-04-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.k09e-154
更新日期:2010-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.52.353
更新日期:2005-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1507/endocrj.EJ16-0112
更新日期:2016-10-29 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.49.285
更新日期:2002-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1507/endocrj.EJ15-0275
更新日期:2015-01-01 00:00:00