Comparative efficacy and safety of tyrosine kinase inhibitors for thyroid cancer: a systematic review and meta-analysis.

abstract：:There is evidence of an association between hypothyroidism and coronary heart disease. We decided to look at the relationship between hypothyroidism and LDL subclasses' pattern including small, dense LDL to define a biochemical basis for better management of the CHD risk of these patients. We utilized a case-control d...

journal_title：Endocrine journal

authors： Abbas JM,Chakraborty J,Akanji AO,Doi SA

更新日期：2008-05-01 00:00:00

abstract：:Although several authors have reported single cases illustrative of some ultrasonographic characteristic of parathyroid carcinoma, the value of ultrasonography for diagnosing this entity remains to be determined. The purpose of our study was to investigate the ultrasonographic features of parathyroid carcinoma in a la...

journal_title：Endocrine journal

authors： Hara H,Igarashi A,Yano Y,Yashiro T,Ueno E,Aiyoshi Y,Ito K,Obara T

更新日期：2001-04-01 00:00:00

abstract：:In contrast to minimally invasive follicular thyroid carcinoma (FTC), widely invasive FTC is aggressive and is associated with a dire prognosis. However, prognostic factors of widely invasive FTC have not been intensively investigated. In this study, we investigated this issue in a series of 79 widely invasive FTC pat...

journal_title：Endocrine journal

authors： Ito Y,Hirokawa M,Masuoka H,Yabuta T,Fukushima M,Kihara M,Higashiyama T,Takamura Y,Kobayashi K,Miya A,Miyauchi A

更新日期：2013-01-01 00:00:00

abstract：:Geographic differences have been reported to affect the morphological and molecular features of papillary thyroid carcinomas (PTCs). The area around Chernobyl is well-known to be iodine-deficient in contrast to Japan, an iodine-rich country. We reviewed histological differences in adult PTC between Ukraine and Japan. ...

journal_title：Endocrine journal

authors： Ito M,Bogdanova T,Zurnadzhy L,Saenko V,Rogounovitch T,Mitsutake N,Kondo H,Maeda S,Nakashima M,Tronko M,Yamashita S

更新日期：2014-01-01 00:00:00

abstract：:To explore the relationship between serum thyrotropin and components of metabolic syndrome in a Chinese cohort. A total of 1534 adult inhabitants in DaDong district of Shenyang were asked to fulfill the questionnaire, complete physical examination and OGTT. Blood samples were collected to test thyrotropin (TSH), fasti...

journal_title：Endocrine journal

authors： Lai Y,Wang J,Jiang F,Wang B,Chen Y,Li M,Liu H,Li C,Xue H,Li N,Yu J,Shi L,Bai X,Hou X,Zhu L,Lu L,Wang S,Xing Q,Teng X,Teng W,Shan Z

更新日期：2011-01-01 00:00:00

abstract：:The relation between thyroid ultrasonography and laboratory, and the relationship of thyroid volume with clinical and anthropometric parameters, are not well clarified. Aim of the study was to investigate normal and hypoechoic-inhomogeneous not nodular thyroid gland in predicting thyroid tests, and to assess the corre...

journal_title：Endocrine journal

authors： Trimboli P,Rossi F,Thorel F,Condorelli E,Laurenti O,Ventura C,Nigri G,Romanelli F,Guarino M,Valabrega S

更新日期：2012-01-01 00:00:00

abstract：:Kallmann syndrome is defined by the association of hypogonadotropic hypogonadism and anosmia. The KAL1 gene is responsible for the X-linked form of Kallmann syndrome. We analyzed the KAL1 gene in 19 Japanese patients with Kallmann syndrome, including 3 patients reported previously, using PCR-direct sequencing method. ...

journal_title：Endocrine journal

authors： Izumi Y,Tatsumi K,Okamoto S,Ogawa T,Hosokawa A,Matsuo T,Kato Y,Fukui H,Amino N

更新日期：2001-04-01 00:00:00

abstract：:The cytologic localization and cellular levels of insulin-like growth factor binding protein-4 (IGFBP-4) in follicular and stromal compartments of normal and polycystic ovary syndrome (PCOS) ovaries during follicular growth and regression were investigated by the avidin/biotin immunoperoxidase method with a polyclonal...

journal_title：Endocrine journal

authors： Peng X,Maruo T,Samoto T,Mochizuki M

更新日期：1996-06-01 00:00:00

abstract：:The presence of human progesterone receptor (PR) mRNA variants has been demonstrated in uterine endometrium and breast tissues as well as in cancer cells of these tissues. While exon deletions by the alternative splicing in these variants have been reported, there are few reports available on the PR mRNA variants with...

journal_title：Endocrine journal

authors： Yamanaka T,Hirata S,Shoda T,Hoshi K

更新日期：2002-08-01 00:00:00

abstract：:Inflammatory lesions of the pituitary gland are rarely encountered. Recently, the concept of immunoglobulin G4 (IgG4)-related systemic disease was proposed in Japan, and more than 20 cases have been reported as possibly associated with infundibulo-hypophysitis since 2000. We herein review such case reports in the publ...

journal_title：Endocrine journal

authors： Shimatsu A,Oki Y,Fujisawa I,Sano T

更新日期：2009-01-01 00:00:00

abstract：:We provide the details of the successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. The patient was a 27-year-old Japanese female healthcare worker who was scheduled to undergo pituitary surgery for Cushing's disease. She had been in close cont...

journal_title：Endocrine journal

authors： Yuno A,Kenmotsu Y,Takahashi Y,Nomoto H,Kameda H,Cho KY,Nakamura A,Yamashita Y,Nakamura J,Nakakubo S,Kamada K,Suzuki M,Sugino H,Inoshita N,Konno S,Miyoshi H,Atsumi T,Sawamura Y,Shimatsu A

更新日期：2020-12-24 00:00:00

abstract：:The neurohypophysial hormone, oxytocin, is involved in the regulation of energy metabolism. Adiponectin (APN) is an adipose tissue-specific serum protein that inversely associates with metabolic syndrome (MetS). High-molecular-weight adiponectin (HMW APN) is considered the active form. In the present study, we aimed t...

journal_title：Endocrine journal

authors： Yuan G,Qian W,Pan R,Jia J,Jiang D,Yang Q,Wang S,Liu Y,Yu S,Hu H,Sun W,Ye J,Mao C,Zhuang R,Zhou L

更新日期：2016-07-30 00:00:00

abstract：:Carcinoma showing thymic-like differentiation (CASTLE) is a rare tumour of the thyroid, which arises from ectopic thymic tissue or remnants of branchial pouches. A systematic review of English literature evidences less than thirty cases; from them, it clearly appears that CASTLE is considered an indolent slow-growing ...

journal_title：Endocrine journal

authors： Cappelli C,Tironi A,Marchetti GP,Pirola I,De Martino E,Delbarba A,Castellano M,Rosei EA

更新日期：2008-08-01 00:00:00

abstract：:Aim of this study was to examine the association between the severity of obstructive sleep apnea (OSA) and dysglycemia in Japanese individuals with and without type 2 diabetes (T2DM). We enrolled 115 individuals diagnosed with OSA with an apnea hypopnea-index (AHI) ≥ 20 in whom continuous positive airway pressure (CPA...

journal_title：Endocrine journal

authors： Kurosawa H,Saisho Y,Fukunaga K,Haraguchi M,Yamasawa W,Kurihara I,Betsuyaku T,Itoh H

更新日期：2018-01-30 00:00:00

abstract：:Sarcopenia is an emerging risk factor for metabolic disorders. No study of the association of sarcopenia with insulin resistance, diabetes, and metabolic syndrome (MS) according to age group and obesity status in the general population has been reported. We investigated these associations in the Korean population. Par...

journal_title：Endocrine journal

authors： Moon SS

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this prospective study was to characterize the changes in serum levels of two proteins produced during the synthesis and degradation of type I collagen, i.e., the carboxyterminal propeptide of type I procollagen (PICP) and the pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICT...

journal_title：Endocrine journal

authors： Yasumizu T,Fukada Y,Hoshi K

更新日期：1999-04-01 00:00:00

abstract：:The purpose of the study was to evaluate the plasminogen activator inhibitor-1 (PAI-1) levels and PAI-1 activity in young and lean women with PCOS and to compare with controls matched for age and weight. Thirty two women with PCOS and 25 weight and age-matched healthy controls participated in this study. Patients were...

journal_title：Endocrine journal

authors： Tarkun I,Cantürk Z,Arslan BC,Türemen E,Tarkun P

更新日期：2004-10-01 00:00:00

abstract：:Maternal Graves' disease (GD) during pregnancy may influence thyroid function in fetuses. Neonates born to mothers with high serum TSH receptor antibody (TRAb) levels have been reported to develop 'neonatal GD'. Therefore, evaluations of serum thyroid hormone and TRAb levels in neonates upon birth are crucial for a pr...

journal_title：Endocrine journal

authors： Wada M,Kita M,Kawasaki K,Kusakabe T,Tagami T,Satoh-Asahara N,Shimatsu A,Hashimoto K

更新日期：2018-05-28 00:00:00

abstract：:We describe a patient with right adrenal tumor detected incidentally. The tumor was diagnosed as pheochromocytoma by endocrinological and radiological studies, and was removed surgically. Graves' disease, which had been in remission for more than two decades after discontinuation of antithyroid drug treatment, relapse...

journal_title：Endocrine journal

authors： Abe M,Mori K,Nagai K,Ito S

更新日期：2003-12-01 00:00:00

abstract：:The onset of physical signs in infants with hypophosphatemic vitamin D resistant rickets (HDRR) has generally been considered to be at the age of 12 months, but the time of appearance of hypophosphatemia and rachitic signs on radiographs remains unclear. We report a prospective study in three neonates whose mothers we...

journal_title：Endocrine journal

authors： Minamitani K,Minagawa M,Yasuda T,Niimi H

更新日期：1996-06-01 00:00:00

abstract：:Estrogen plays pivotal roles in body weight regulation through its effects on central estrogen receptor-α (ERα) expression. ERα is found on neurons that express the hypothalamic anorexigenic factors steroidogenic factor-1 (SF-1) and pro-opiomelanocortin (POMC) mediate these effects of estrogen. As the gonadal hormonal...

journal_title：Endocrine journal

authors： Iwasa T,Matsuzaki T,Mayila Y,Yano K,Irahara M

更新日期：2017-12-28 00:00:00

abstract：:Components of cyclinD1/cyclin-dependent kinase 4 (CDK4)/p16INK4a/pRb pathway are the frequent target of many tumor types. We examined the role of retinoblastoma susceptibility gene (RB1) and the CDK4 gene in human pituitary tumorigenesis. For the RB1 gene, pRb expression and loss of heterozygosity (LOH) on 13q in pitu...

journal_title：Endocrine journal

authors： Honda S,Tanaka-Kosugi C,Yamada S,Sano T,Matsumoto T,Itakura M,Yoshimoto K

更新日期：2003-06-01 00:00:00

abstract：:Estrogen-secreting adrenal cancers are extremely rare, with feminizing symptoms attributed to aromatase expression in the adrenal tumor. We describe a case of hypogonadotropic hypogonadism as a consequence of aberrant aromatase expression in a patient with adrenocortical adenocarcinoma. A 54 year-old man presented wit...

journal_title：Endocrine journal

authors： Advani A,Johnson SJ,Nicol MR,Papacleovoulou G,Evans DB,Vaikkakara S,Mason JI,Quinton R

更新日期：2010-01-01 00:00:00

abstract：:The effect of add-on therapy with sitagliptin on glycemic control was prospectively investigated in patients with type 2 diabetes mellitus (T2DM) receiving insulin alone or insulin combined with oral antidiabetic drugs. Seventy-one patients were evaluated (38 men and 33 women aged 63.9 ± 10.2 years). They were divided...

journal_title：Endocrine journal

authors： Katsuno T,Ikeda H,Ida K,Miyagawa J,Namba M

更新日期：2013-01-01 00:00:00

abstract：:We assessed the incidence of elderly patients in Japanese acromegalics and the characteristics of their clinical presentation. We also evaluated the safety and efficacy of transsphenoidal surgery (TSS) in this patient group. During the 28-year period from 1980 to 2007 we treated 290 patients with acromegaly at our hos...

journal_title：Endocrine journal

authors： Arita K,Hirano H,Yunoue S,Fujio S,Tominaga A,Sakoguchi T,Sugiyama K,Kurisu K

更新日期：2008-10-01 00:00:00

abstract：:Age is an important prognostic factor in papillary thyroid carcinoma (PTC). In this study, we investigated the difference in prognosis of 7 subsets of PTC patients without distant metastasis at presentation or a history of radiation exposure (20 years or younger, 21-30 years, 31-40 years, 41-50 years, 51-60 years, 61...

journal_title：Endocrine journal

authors： Ito Y,Miyauchi A,Kihara M,Takamura Y,Kobayashi K,Miya A

更新日期：2012-01-01 00:00:00

abstract：:Sera from 30 Japanese insulin-dependent diabetes mellitus (IDDM) patients of short duration were examined to determine whether they had antibodies to proteolytic fragments of islet antigen, the molecular weights of which were 37,000 and/or 40,000 Mr (37KAb). The median age and disease duration of the patients were 13 ...

journal_title：Endocrine journal

authors： Ozawa Y,Kasuga A,Maruyama T,Kitamura Y,Amemiya S,Ishihara T,Suzuki R,Saruta T

更新日期：1996-12-01 00:00:00

abstract：:We previously identified an approximately 200 bp "minimal promoter" of the rat TSH receptor (TSHR) gene which is essential for the promoter activity. In the present study, we have cloned and characterized an upstream region of the TSHR promoter to disclose additional functional element(s). We screened a rat genomic li...

journal_title：Endocrine journal

authors： Ikuyama S,Ohe K,Takayanagi R,Kohn LD,Nawata H

更新日期：1997-04-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a form of non-Langerhans histiocytosis. In this report, we show a case of ECD presenting diabetes insipidus and multiple xanthogranulomas received glucocorticoid treatment over a year. During this period, xanthogranulomas improved in response to the glucocorticoid therapy. Furthermore,...

journal_title：Endocrine journal

authors： Taguchi T,Iwasaki Y,Asaba K,Yoshida T,Takao T,Ikeno F,Nakajima H,Kodama H,Hashimoto K

更新日期：2008-03-01 00:00:00

abstract：:Pathogenesis of pseudohypoparathyroidism type 1b (PHP-1b) is related to the loss of methylation at the GNAS exon A/B region, which is combined with epigenetic defects at other differentially methylated GNAS regions in most sporadic cases. In this study, we established a method for evaluating the methylation status of...

journal_title：Endocrine journal

authors： Kinoshita K,Minagawa M,Takatani T,Takatani R,Ohashi M,Kohno Y

更新日期：2011-01-01 00:00:00