Abstract:
:The aim of this prospective, randomized, double blind study was to compare the efficacy of methotrexate and hyperosmolar glucose injected directly into the extra-uterine gestational sac under laparoscopic vision. The study included twenty women with ectopic pregnancy. Inclusion criteria were intact tubal pregnancy, not exceeding 4 cm in diameter, rising or plateauing betahCG levels, and no evidence of intra-abdominal bleeding. The patients were treated by laparoscopically guided injection of 3 mL fluid into the area containing the tubal pregnancy. The fluid contained either 25 mg methotrexate (n=9) or 50% glucose (n=9). Daily decrease in betahCG levels was faster in patients treated by methotrexate (median 8.7%) than in those treated by hyperosmolar glucose (median 4.8%), p=0.17. The study was discontinued due to a higher failure rate in the group treated by hyperosmolar glucose. In conclusion, local injection of methotrexate is superior to hyperosmolar glucose. It can be used as an alternative to salpingostomy or salpingotomy whenever laparoscopy is performed for the diagnosis and treatment of extra-uterine pregnancy.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Sadan O,Ginath S,Debby A,Rotmensch S,Golan A,Zakut H,Glezerman Mdoi
10.1007/s004040000149subject
Has Abstractpub_date
2001-05-01 00:00:00pages
82-4issue
2eissn
0932-0067issn
1432-0711journal_volume
265pub_type
临床试验,杂志文章,随机对照试验abstract:PURPOSE:The aim of this study was to evaluate the conventional sperm parameters, level of intracellular reactive oxygen species (ROS), DNA fragmentation (DF) and dysfunction of mitochondrial membrane potential (MMP) after semen preparation techniques with flow cytometry. METHODS:Semen samples were obtained from 28 men...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2946-1
更新日期:2014-01-01 00:00:00
abstract::Interleukin-6 (IL-6) is a pleiotropic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied the IL-6 secretion in vitro of 15 human cell lines derived from both squamous cell carcinoma (SCC) and adenocarcinoma of the uterine cervix. Four of the eight ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF01370929
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of bupivacaine-soaked spongostan in cesarean section wound for postoperative anxiety level, satisfaction and early postpartum depression rate. METHODS:A total of 121 women, American Society of Anesthesiologists physical status I-II, scheduled to undergo general anesthesia and electi...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-014-3201-0
更新日期:2014-08-01 00:00:00
abstract::Uterine leiomyomas affect 20-30 % of women 35 years and older. Extrauterine leiomyomas are rare and present a greater diagnostic challenge. Those unusual growth patterns occur more often in women of reproductive age with a history of hysterectomy or surgery for uterine leiomyomas. They have been reported in the litera...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-014-3356-8
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Primary small cell carcinoma of the endometrium is very rare, and there have been no reports on KIT and PDGFRA in endometrial small cell carcinoma. CASE REPORT:An 87-year-old woman was admitted to our hospital because of genital bleeding. Endometrial cytology and biopsy revealed small cell carcinoma. Scruti...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1324-5
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To determine the accuracy of clinical criteria relative to Nugent's criteria for diagnosing bacterial vaginosis (BV) in the pregnant patient. METHODS:This prospective study was conducted in pregnant patients requiring a speculum examination in an ER triage system. Determination was made of vaginal pH, whiff ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0766-5
更新日期:2009-04-01 00:00:00
abstract::Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl. Serum ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040000114
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:Human papillomavirus (HPV) can cause condylomata acuminata, also known as genital warts. Our aim was to evaluate the long-term recurrence of genital warts after primary carbon dioxide laser treatment before the introduction of the vaccination against HPV. METHODS:Recurrence rate and localization of genital war...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05242-5
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:To analyze the effect of Chlamydia trachomatis (C. trachomatis) on adverse pregnancy outcomes based on the currently available evidence. METHODS:Multiple databases were comprehensively searched from the available date of inception through December 9, 2019. The effect of C. trachomatis on adverse pregnancy outc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00404-020-05664-6
更新日期:2020-09-01 00:00:00
abstract::The objective of the study was to examine the teratogenic potential of surgery under anesthesia during pregnancy in the large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1994. An analysis of cases with congenital abnormalities and matched healthy controls was p...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040050221
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:With an estimated incidence of one to two per one million women, the endometrial stromal sarcoma (ESS) is a rare disease. It is subclassified into a high-grade and a prognostically better low-grade type. Evidence-based data for a standardized therapy is lacking. CASE REPORT:A 32-year-old obese nulligravid...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0100-4
更新日期:2006-04-01 00:00:00
abstract:PRESENTATION:We detected an unusual placental lake under the membranes between the two lobes of a placenta bilobate with a turbulent blood flow in it. This was an extraordinary maternal lake: simply the accumulation of maternal blood inside the intervillous space in an area where villous structures were absent between ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-004-0649-3
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Our goal is to identify subgroups of women undergoing breast-conserving therapy (BCT) who are at increased risk for requiring a secondary surgical procedure, and to identify tumor and patient profiles that will allow surgeons to anticipate the need for taking larger margins when removing the tumor. METHODS:...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2401-8
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Despite the well-known second trimester ultrasound signs, current possibilities of in utero surgical repair of open spina bifida require a timely detection of the spine defect. OBJECTIVE:To evaluate the diagnostic accuracy of the ratio between brain stem (BS) diameter and its distance to the occipital bone ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析
doi:10.1007/s00404-019-05422-3
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:This study is designed to explore the correlation between AMH levels and IR in normal weight PCOS women. MATERIALS AND METHODS:This prospective study was conducted on 55 patients, who were admitted to obstetrics and gynecology department of a university clinic. Study group was consisted of 34 patients diagnose...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2833-9
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:To evaluate the clinical efficacy of letrozole on ovulation induction and hormone replacement therapy (HRT) during endometrial preparation for frozen-thawed embryo transfer (FET). METHODS:We analyzed totally 1,230 cycles of patients that underwent FET from October 2010 to September 2012. Seven hundred and thir...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-013-3044-0
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:Case report of a rare combination of a trisomy 18 and 21 in a dizygotic twin pregnancy in a woman with a history of recurrent miscarriage, a neonatal death, no living offspring and Graves disease. METHODS:Case report and literature search. RESULTS:Only one other report in the literature of a combined trisom...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0378-5
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:Modest increases of serum progesterone at human chorionic gonadotrophin (hCG) administration in controlled ovarian hyperstimulation (COH) cycles have been shown to have a negative impact on pregnancy outcomes. The aim of this study was to identify early predictors of progesterone elevation at hCG. DESIGN:Pregn...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3167-y
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:Decreased oocyte maturation rate (OMR) is associated with worse clinical outcomes in IVF/ICSI cycles. The clinical features inducing decreased OMR remain unknown. The study is designed to explore the factors influencing the incidence of decreased OMR and its effects on clinical outcomes. METHODS:This is a retr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4958-3
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Membranous dysmenorrhea is a rare entity involving expulsion of fragments of endometrium retaining the shape of the uterus. The condition is often linked to high progesterone levels. An association with a chronic fatigue syndrome was never described. CASE:A 44-year-old woman with a chronic fatigue syndrome ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-008-0795-0
更新日期:2009-05-01 00:00:00
abstract::Pregnancy-associated plasma protein A (PAPP-A) is a large glycoprotein produced mainly by the trophoblast during pregnancy and released into the maternal circulation. Its biological function is unknown. In the second trimester i.e. when Down syndrome (DS) screening is routinely performed, the level of maternal serum P...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00634490
更新日期:1995-01-01 00:00:00
abstract:INTRODUCTION:Conization of the uterine cervix is a common gynecological procedure that sometimes causes cervical stenosis which creates difficulties for future gynecological procedures. MATERIAL:We present a very unusual case where strenuous effort was needed to obtain safe access to the endocervical canal and endomet...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1832-3
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:In this trial, we used a previously developed prototype software to assess aesthetic results after reconstructive surgery for congenital breast asymmetry using automated anthropometry. To prove the consensus between the manual and automatic digital measurements, we evaluated the software by comparing the manual...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05862-2
更新日期:2020-11-12 00:00:00
abstract:INTRODUCTION:Radiotherapy is known to cause rarely various malignancies including leukemia, sarcoma, and thyroid and lung carcinoma. Post-radiation sarcomas account for 0.5-5.5% of all sarcomas; and include extra skeletal osteosarcoma, fibrosarcoma leiomyosarcoma, and malignant fibrous histiocytoma. Reports on post rad...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1699-3
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Episiotomy is one of the most commonly performed procedures among women of childbearing age in the United States. In 2005, a major systematic review conducted by Hartmann and colleagues recommended against routine use of episiotomy and was widely covered in the media. We assessed the impact of the Hartman et al...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2904-y
更新日期:2013-12-01 00:00:00
abstract::The goal of infertility surgery is to restore anatomic relationship to as close to normal as possible maximizing the chances for conception and intrauterine pregnancy. The outcome has been markedly, improved by the advent of microsurgical techniques. More than 10 years of microsurgical experience have enabled us to cl...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02417345
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:Sirenomelia is caused by atrophy of the lower extremities that is commonly associated with gastrointestinal and urogenital malformations. METHODS:Embryogenic environmental theories and systematic review of the literature are reported. RESULTS:Genetic basis of the condition has been demonstrated in the animal ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-013-2847-3
更新日期:2013-07-01 00:00:00
abstract:AIMS AND OBJECTIVES:To compare the three techniques of hysterectomy-total laparoscopic hysterectomy (TLH), laparoscopic assisted vaginal hysterectomy (LAVH) and non-descent vaginal hysterectomy (NDVH). MATERIALS AND METHODS:Ninety women with benign disease of uterus with failed medical management or not amenable to me...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-010-1778-5
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:Cervical cancer is the most common malignant tumors in women leading to serious morbidity and mortality worldwide, especially among developing countries. A main cause of the disease is the high-risk human papillomavirus (HR-HPV) infection. HSIL usually progress to cervical cancer, and low-grade lesions, incl...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4931-1
更新日期:2019-01-01 00:00:00
abstract::A kit using mouse monoclonal antibody against human alpha-fetoprotein (anti-AFP kit) has been developed. Cervical secretion (n = 34) and vaginal fluid (n = 15) was obtained from 30 pregnant volunteers. All 31 specimens obtained from women with intact membranes tested negative while all 18 specimens from women with pre...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00634709
更新日期:1995-01-01 00:00:00