Abstract：
:Depressive mixed states (major depressive episodes [MDE] with some hypomanic symptoms) are not classified in DSM-IV. The aim of the present study was to determine the prevalence of depressive mixed states in depressed outpatients, and to compare bipolar II with unipolar depressive mixed states. Seventy consecutive bipolar II and unipolar depressed outpatients were interviewed using the DSM-IV Structured Clinical Interview (SCID). At least one hypomanic symptom was present in 90% of patients, and three or more in 28.5%. Symptoms of depressive mixed states included irritable mood, distractibility, racing thoughts, and increased talking. Bipolar II subjects had more concurrent hypomanic symptoms (three or more in 48.7% v 3.2%, P = 0.000). Depressive mixed states with three or more hypomanic symptoms correctly classified 70.0% of bipolar II subjects. These findings have important treatment implications, as antidepressants may worsen the symptoms of depressive mixed states, and mood stabilizers can be useful.
journal_name
Compr Psychiatryjournal_title
Comprehensive psychiatryauthors
Benazzi Fdoi
10.1053/comp.2001.21216subject
Has Abstractpub_date
2001-03-01 00:00:00pages
139-43issue
2eissn
0010-440Xissn
1532-8384pii
S0010-440X(01)68482-7journal_volume
42pub_type
杂志文章abstract：:Although previous studies have suggested the inadequacy of the two-factor models of positive and negative symptoms in schizophrenia, confirmatory testing of the putative three-factor models is needed. Using a sample of 193 individuals diagnosed with schizophrenia, this study tested the relative goodness-of-fit of one-...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(94)90016-7
更新日期：1994-07-01 00:00:00
abstract：BACKGROUND:Depression after acute coronary syndromes (ACS) is an important risk factor for further coronary events; but the influence of anhedonia, the decreased capacity to experience pleasure, has received little attention. The aim of the study was to investigate the effects of anhedonia on prognosis at 3-year follow...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2009.01.011
更新日期：2010-01-01 00:00:00
abstract：:Dimensional approaches to psychiatric disorders have shown an increased relevance in the ongoing debate for the forthcoming Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. In line with previously validated instruments for the assessment of different mood, anxiety, eating and psychotic spectra, we...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2008.11.006
更新日期：2009-09-01 00:00:00
abstract：:Kinsey concluded that homosexuality and heterosexuality were distributed dimensionally in the normal population, a significant percentage of whom experienced homosexual feelings. This conclusion has been ignored by most sex researchers. Twenty men seeking treatment for compulsive sexual behaviours reported a dimension...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(91)90069-o
更新日期：1991-01-01 00:00:00
abstract：:Two hundred twenty-four first-degree relatives of patients with psychotic disorders were administered the Structured Interview for DSM-III Personality Disorders (SIDP) and completed a self-report instrument to assess dimensions of the five-factor model of personality. All of the DSM-III personality disorders were rela...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(93)90003-m
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVE:Sleep problems are a clinical and/or diagnostic feature for a broad array of mood, substance use, and anxiety disorders, including posttraumatic stress disorder (PTSD). Previous research by Leskin et al (Leskin GA, Woodward SH, Young HE, Sheikh J. Effects of comorbid diagnoses on sleep disturbance in PTSD. J ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2011.01.007
更新日期：2011-11-01 00:00:00
abstract：:The history of the positive/negative terminology, as applied to psychiatric symptoms, can be divided into an early period of original meanings, a second one of French elaboration, and the current revival. This report addresses issues concerning the meaning, referent, and nature of the link between the positive and the...
journal_title：Comprehensive psychiatry
pub_type： 历史文章,杂志文章
doi：10.1016/0010-440x(91)90016-6
更新日期：1991-09-01 00:00:00
abstract：:This report studies the personality of individuals who suffer from dissociative trance disorder and examines whether the personality profiles could predict the individual's frequency of trance states. A total of 58 cases were given the Eysenck Personality Questionnaire (EPQ) and their personal information harvested fr...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1053/comp.2002.30808
更新日期：2002-03-01 00:00:00
abstract：:Childhood sexual abuse has been associated with adult dissociative symptomatology. The purpose of this study was to examine the relationship between specific characteristics of sexual abuse and dissociative experiences in adulthood. Fifty-six female inpatients with a history of physical abuse and severe sexual abuse r...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(94)90230-5
更新日期：1994-11-01 00:00:00
abstract：:People who engage in nonsuicidal self-injury (NSSI) often report high levels of impulsivity. However, results from behavioral tasks measuring impulsivity have been mixed: those with a history of NSSI generally perform comparably to healthy controls. Recent research suggests, however, that people who self-injure have s...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2016.10.011
更新日期：2017-02-01 00:00:00
abstract：:Our aim was to describe the clinical features of 35% CO2-induced panic attacks in patients with panic disorder (PD) (Diagnostic and Statistical Manual and Mental Disorders, Fourth Edition) and compare them with the last spontaneous panic attack in patients with PD who had not had a panic attack after the 35% CO2 chall...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.comppsych.2005.07.007
更新日期：2006-05-01 00:00:00
abstract：:We examined the stable relations between coping style and cognitive function in schizophrenic and depressed patients and in patient and normal controls on two test occasions. The results show that a poor self-report of coping style is independent of psychiatric diagnosis, but there are associations with both subjectiv...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(97)90930-5
更新日期：1997-11-01 00:00:00
abstract：:Previous studies have shown that mindfulness meditation may improve well-being in healthy individuals and be effective in the treatment of mental and neurological disorders. Here, we investigated the effects of an 8-week mindfulness-mediation program on the personality profiles of three groups of healthy individuals w...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2014.03.009
更新日期：2014-07-01 00:00:00
abstract：:We describe our experience with a case of folie à famille with role reversal, including the long-term course. In addition, the case reports published since 1974 were reviewed and an overview is given of the psychoanalytic and system theory concepts on the pathogenesis of induced psychotic disorder. The inductor often ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,评审
doi：10.1016/0010-440x(93)90056-a
更新日期：1993-03-01 00:00:00
abstract：OBJECTIVE:A new diagnostic category called Hoarding Disorder (HD) has been proposed for inclusion in DSM-5. It is paramount that this addition does not result in an over-pathologization of normative behavior. Collectors constitute a valid population within which to test the diagnostic boundaries of HD. The current stud...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2012.07.063
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:High levels of anhedonia have been found in patients with schizophrenia; specifically they report higher levels of social anhedonia rather than physical anhedonia, and further, in the anticipatory rather than consummatory facets of pleasure. Nonetheless, contrasting results emerged regarding the underlying m...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2015.07.011
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Most research on the assessment and characteristics of prolonged grief disorder (PGD) has been conducted in Western bereaved samples. Limited information about PGD in Chinese samples exists. This study aims to validate the Chinese version of the Inventory of Complicated grief (ICG), examine the distinctivene...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2015.12.001
更新日期：2016-04-01 00:00:00
abstract：:Personality disorders are common in subjects with panic disorder. Personality disorders have been shown to affect the course of panic disorder. The purpose of this study was to examine which personality disorders affect clinical severity in subjects with panic disorder. This study included 122 adults (71 women, 41 men...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.07.015
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The number of previous episodes in patients with BD is a variable widely used for both clinical and research purposes. The aim of this study was to compare the number of episodes retrospectively reported by euthymic BD subjects with that registered by their psychiatrists during a follow-up period. METHODS:F...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2015.11.005
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Methylenetetrahydrofolate reductase (MTHFR) is the critical enzyme in biotransformation. The polymorphism of MTHFR is a risk factor for schizophrenia. However, whether the MTHFR polymorphism is associated with schizophrenia disease phenotypes and what is the underlying mechanism of MTHFR polymorphism in schi...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2019.152121
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Theory of mind (ToM) can be divided into cognitive and affective ToM, and a distinction can be made between overmentalizing and undermentalizing errors. Research has shown that ToM in schizophrenia is associated with non-social and social cognition, and with clinical symptoms. In this study, we investigate c...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2018.05.002
更新日期：2018-08-01 00:00:00
abstract：AIMS:This study was designed to evaluate the relationship between insight and the severity of psychotic symptomatology in a sample of patients in an acute phase of psychosis, as well as to analyze the relationship between insight and the symptomatic profile of the patient. In addition, the role of general cognitive abi...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2011.08.008
更新日期：2012-07-01 00:00:00
abstract：:Primary hyperhidrosis is characterized by excessive sweating and often accompanied by social avoidance. Social anxiety disorder (SAD) is characterized by fear and avoidance of social situations, often partly related to fears of showing signs of excessive autonomic nervous system activation, such as sweating. To clarif...
journal_title：Comprehensive psychiatry
pub_type： 临床试验,杂志文章
doi：10.1016/j.comppsych.2012.04.009
更新日期：2012-11-01 00:00:00
abstract：:Borderline personality disorder (BPD) is characterized by interpersonal disturbances, but the neurocognitive aspects of these symptoms are poorly understood. We hypothesized that patients with BPD have impaired perception of emotional expressions, which are related to symptoms of interpersonal dysfunction. To control ...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2006.03.005
更新日期：2006-11-01 00:00:00
abstract：:The purpose of the study was to identify psychiatric symptoms, neurological impairments, and situational factors associated with the emergence of violence and with its persistence. Psychiatric symptoms were assessed in newly admitted physically assaultive psychiatric patients and nonviolent controls. Patients were tha...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/s0010-440x(97)90031-6
更新日期：1997-07-01 00:00:00
abstract：:The Axis I phenomenology of 50 outpatients meeting both Diagnostic Interview for Borderlines (DIB) and DSM-III criteria for Borderline Personality Disorder (BPD), 29 outpatients meeting DSM-III criteria for Antisocial Personality Disorder (APD), and 26 outpatients meeting DSM-III criteria for Dsythymic Disorder as wel...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/0010-440x(89)90067-9
更新日期：1989-03-01 00:00:00
abstract：BACKGROUND:OCD causes impairment in different areas of the patients' quality of life (QoL), such as sociability, family relationships, and occupational performance. The literature has emphasized the relevance of assessing QoL as a critical outcome in mental health studies. AIMS:The aim of this study was to investigate...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2018.07.007
更新日期：2018-10-01 00:00:00
abstract：:More than a decade ago, a consensus panel recommended that remission be defined on the 17-item version of the Hamilton Rating Scale for Depression (HAM-D) as a cutoff of less than 7. Recently, some investigators have suggested that this threshold to define remission may be too high. If true, this means that heterogene...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2006.10.005
更新日期：2007-03-01 00:00:00
abstract：:The Defense Style Questionnaire (DSQ) assesses defensive behavior by empirically evaluating conscious derivatives of defense and coping mechanisms in everyday life. It was developed on the assumption that defenses can be ordered along a maturity-immaturity continuum and tend to group into clusters, or defensive styles...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章
doi：10.1016/j.comppsych.2004.07.012
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:We hypothesized that subjects with obsessive-compulsive disorder (OCD) who received extended-release fluvoxamine (fluvoxamine ER) in a 12-week placebo-controlled trial would exhibit improvements in psychosocial domains of health-related quality of life (HRQOL) and that additional improvements would occur afte...
journal_title：Comprehensive psychiatry
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.comppsych.2009.10.001
更新日期：2010-07-01 00:00:00
