Abstract:
OBJECTIVE:To study the effects of trabeculectomy and needling revision of poorly functioning blebs on the optic nerve head (ONH) circulation in patients with primary open-angle glaucoma (POAG). DESIGN:Prospective, nonrandomized, self-controlled trial. PARTICIPANTS:Nineteen POAG patients (age range, 52 +/- 12 years; mean +/- standard deviation) undergoing trabeculectomy and six POAG patients (age range, 62 +/- 14 years) undergoing needling revision of the bleb. METHODS:Using the laser speckle method, the normalized blur (NB) value, a quantitative index of blood velocity, was determined every 0.125 seconds and averaged more than three cardiac pulses in the optic nerve head (NB(ONH)). MAIN OUTCOME MEASURES:The NB(ONH) and intraocular pressure (IOP) in both eyes, and blood pressure (BP) and pulse rate (PR) were measured before and 2 days and 1, 4, and 8 weeks after trabeculectomy, and also before and 10 and 40 min after needling procedures. RESULTS:Intraocular pressure in the operated eye was significantly decreased after trabeculectomy or needling procedures, and the ocular perfusion pressure was significantly increased by a maximum of 38%. The IOP in the unoperated eye, BP, and PR did not significantly change. The NB(ONH) did not significantly change in either the operated or unoperated eye. CONCLUSIONS:Trabeculectomy and needling procedures induced little change in the ONH circulation.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Tamaki Y,Araie M,Hasegawa T,Nagahara Mdoi
10.1016/s0161-6420(00)00541-8subject
Has Abstractpub_date
2001-03-01 00:00:00pages
627-32issue
3eissn
0161-6420issn
1549-4713pii
S0161-6420(00)00541-8journal_volume
108pub_type
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