Myelophthisis as a solitary manifestation of failure from rectal carcinoma. A Batson phenomenon?

Abstract:

:Rectal carcinoma is uncommonly associated with systemic metastases in the absence of liver metastases, reflecting the predilection for spread via the portal system. Occasionally, isolated lung metastases are seen, which are usually attributed to spread via the portosystemic anastomoses in the distal rectum. However, myelophthisis is an unreported complication of rectal cancer as an isolated form of systemic failure. We present a case of fatal myelophthisis associated with otherwise localized rectal carcinoma secondary to metastatic rectal cancer. This observation led to the hypothesis that spread to the bone marrow occurred via a "third circulation," the Batson plexus, a network of deep pelvic veins with rich anastomoses to the vertebral plexus.

journal_name

Arch Pathol Lab Med

authors

Mathew P,Fleming D,Adegboyega PA

doi

10.1043/0003-9985(2000)124<1228:MAASMO>2.0.CO;2

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

1228-30

issue

8

eissn

0003-9985

issn

1543-2165

journal_volume

124

pub_type

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