Microcystic transitional cell carcinoma: a report of 2 cases arising in the renal pelvis.

Abstract:

:Microcystic transitional cell carcinoma is a rare variant of urothelial carcinoma; to date, it has been described only in the urinary bladder. We report 2 cases of microcystic transitional cell carcinoma arising in the renal pelvis. The first case occurred in a 73-year-old man with a history of superficially invasive transitional cell carcinoma who presented with macroscopic hematuria and anemia. The second case occurred in a 62-year-old woman who had no relevant medical history and presented with hematuria. Computed tomographic scan revealed a tumor of the renal pelvis. In both cases, microscopic examination showed invasive transitional cell carcinoma with prominent cystic features. The cysts were irregular in size and were deeply infiltrative. The cysts were lined by single or multiple layers of cuboidal or flattened cells with minimal cytological atypia. The first patient died of his disease 18 months after presentation. The second patient remained well at her 6-month follow-up examination. Microcystic transitional cell carcinoma is an unusual, deceptively bland variant of urothelial carcinoma, which can mimic benign lesions.

journal_name

Arch Pathol Lab Med

authors

Leroy X,Leteurtre E,De La Taille A,Augusto D,Biserte J,Gosselin B

doi

10.1043/0003-9985(2002)126<0859:MTCC>2.0.CO;2

subject

Has Abstract

pub_date

2002-07-01 00:00:00

pages

859-61

issue

7

eissn

0003-9985

issn

1543-2165

journal_volume

126

pub_type

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