Lung cancer genotype-based therapy and predictive biomarkers: present and future.

abstract：:Sarcoidosis is a chronic systemic disease of unknown etiology, which is characterized by noncaseating epitheloid granulomas usually in multiple organs. Here we describe changes in cytokine mRNA expression by peripheral blood mononuclear cells (PBMCs) and changes of cytokine protein levels in plasma over a time course ...

journal_title：Archives of pathology & laboratory medicine

authors： Schoppet M,Pankuweit S,Maisch B

更新日期：2003-09-01 00:00:00

abstract：CONTEXT:Tumors of the head and neck commonly arise from the squamous and respiratory mucosa that lines the nasal and oral cavity, sinuses, pharynx, and larynx. The rate of oropharyngeal cancers diagnosed among Americans younger than 50 years is increasing. Infection of the oropharynx and tonsils by the human papillomav...

journal_title：Archives of pathology & laboratory medicine

authors： Black CC,Bentley HA,Davis TH,Tsongalis GJ

更新日期：2010-12-01 00:00:00

abstract：:Rosai-Dorfman disease is an idiopathic histiocytic disorder of lymph nodes and extranodal sites. Central nervous system manifestations of this disease are rare, and to our knowledge only 16 cases of intracranial involvement have been reported previously. Intracranial Rosai-Dorfman disease clinically and radiologically...

journal_title：Archives of pathology & laboratory medicine

authors： Deodhare SS,Ang LC,Bilbao JM

更新日期：1998-02-01 00:00:00

abstract：CONTEXT:Lesions associated with monoclonal light and heavy chains display a variety of glomerular, tubular interstitial, and vascular manifestations. While some of the entities are well recognized, including light and heavy chain deposition diseases, AL (light chain) and AH (heavy chain) amyloidosis, and light chain ("...

journal_title：Archives of pathology & laboratory medicine

authors： Herrera GA

更新日期：2014-10-01 00:00:00

abstract：CONTEXT:KRAS mutations can be detected in approximately 30% to 40% of all patients with colorectal cancer. Several recent studies have shown that patients with KRAS mutations in codons 12 or 13 in metastatic tumors do not benefit from anti-epidermal growth factor receptor therapy with cetuximab or panitumumab. OBJECTI...

journal_title：Archives of pathology & laboratory medicine

authors： Monzon FA,Ogino S,Hammond ME,Halling KC,Bloom KJ,Nikiforova MN

更新日期：2009-10-01 00:00:00

abstract：:The interrelationship between lymphocytes and hepatocytes was examined by light and electron microscopy, using epoxy-resin embedded thick and thin sections of biopsy liver tissues from patients with chronic persistent hepatitis (CPH) and chronic active liver disease (CALD). Close apposition of lymphocytes with hepatoc...

journal_title：Archives of pathology & laboratory medicine

authors： Kawanishi H

更新日期：1977-06-01 00:00:00

abstract：:A study was undertaken of 14 autopsy cases with pigmented rib cartilage. Twelve of these patients had been treated with levodopa because of Parkinson's disease for at least 6 years, and two had been treated with methyldopa because of essential hypertension for 19 years. Thirty-two percent of the autopsy cases of Parki...

journal_title：Archives of pathology & laboratory medicine

authors： Rausing A,Rosén U

更新日期：1994-05-01 00:00:00

abstract：CONTEXT:Newborns are often screened prior to discharge for hyperbilirubinemia. Transcutaneous bilirubin analyzers, such as the BiliChek, are promoted as screening tools, but it is unclear whether they also function well as monitoring devices. Newborns on home phototherapy require frequent determinations of serum biliru...

journal_title：Archives of pathology & laboratory medicine

authors： Reyes CA,Stednitz DR,Hahn C,Mutchie KD,McCullough SR,Kronberg K

更新日期：2008-04-01 00:00:00

abstract：:Values for total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and LDH isoenzymes 1 and 2 were determined in 80 patients with acute myocardial infarction (AMI) and in 40 without AMI every 24 hours up to 15 days after admission, when total serum LDH level returned to normal. The sensitivity, specificity, and effici...

journal_title：Archives of pathology & laboratory medicine

authors： Rotenberg Z,Davidson E,Weinberger I,Fuchs J,Sperling O,Agmon J

更新日期：1988-09-01 00:00:00

abstract：:Levamisole-induced vasculitis is a characteristic cutaneous vasculitis syndrome associated with the use of levamisole-adulterated cocaine. Patients will typically present with a painful, purpuric rash in a retiform or stellate pattern with or without central necrosis involving the extremities, trunk, nasal tip, digits...

journal_title：Archives of pathology & laboratory medicine

authors： Roberts JA,Chévez-Barrios P

更新日期：2015-08-01 00:00:00

abstract：:Sclerosing angiomatoid nodular transformation (SANT) is a recently recognized nonneoplastic vascular lesion of the spleen with fewer than 30 cases described. Microscopically, SANT consists of multiple well-circumscribed vascular/angiomatoid nodules showing plump endothelial cell and extravasated erythrocytes. The nodu...

journal_title：Archives of pathology & laboratory medicine

authors： Awamleh AA,Perez-Ordoñez B

更新日期：2007-06-01 00:00:00

abstract：CONTEXT:CDX2, a critical nuclear transcription factor for intestinal development, is expressed in intestinal epithelium and adenocarcinomas. OBJECTIVES:To determine if CDX2 is a useful marker for intestinal-type differentiation and to correlate tumor histology with CDX2 staining in colorectal adenocarcinomas. DESIGN:...

journal_title：Archives of pathology & laboratory medicine

authors： De Lott LB,Morrison C,Suster S,Cohn DE,Frankel WL

更新日期：2005-09-01 00:00:00

abstract：:Serum samples from 76 patients with neutropenia and 34 control subjects were analyzed for levels of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, interleukin 1 alpha, and tumor necrosis factor beta. Clinical correlates and duration of neutropenia were determined insofar as po...

journal_title：Archives of pathology & laboratory medicine

authors： Greendyke RM,Sharma K,Gifford FR

更新日期：1994-12-01 00:00:00

abstract：:We investigated how route of infection with Treponema pallidum affects cellular responses of various lymphoid tissues. Lymphoid cells from spleens and lymph nodes of rabbits infected intradermally with T pallidum showed enhanced in vitro responses to treponemal antigens when cultured in autologous rabbit serum. Intrav...

journal_title：Archives of pathology & laboratory medicine

authors： Maret SM,Rauchbach AS,Folds JD

更新日期：1982-09-01 00:00:00

abstract：:Bloom syndrome is a rare autosomal recessive disorder characterized by normally proportioned but strikingly small body size, a characteristic facies and photosensitive facial skin lesion, immunodeficiency, and a marked predisposition to development of a variety of cancers. We describe here, we believe for the first ti...

journal_title：Archives of pathology & laboratory medicine

authors： Wang J,Cornford ME,German J,French SW

更新日期：1999-04-01 00:00:00

abstract：:A necrotizing retinopathy following a vesicular cutaneous eruption in the distribution of the right trigeminal nerve developed in a patient who had been receiving systemic corticosteroid therapy one week prior to the onset of herpes zoster ophthalmicus. Seven weeks after the herpetic symptoms began, the patient died o...

journal_title：Archives of pathology & laboratory medicine

authors： Schwartz JN,Cashwell F,Hawkins HK,Klintworth GK

更新日期：1976-07-01 00:00:00

abstract：:Invasive lobular carcinoma of the breast is a relatively common diagnosis. However, other carcinomatous as well as noncarcinomatous neoplasms, either primary or metastatic to the breast, may mimic invasive lobular carcinoma. As treatment may differ, establishing the correct diagnosis is paramount to providing the appr...

journal_title：Archives of pathology & laboratory medicine

authors： Ishikawa MK,Pinsky RW,Smith LB,Jorns JM

更新日期：2015-10-01 00:00:00

abstract：:A 48-year-old Japanese woman died of multiple myeloma (lambda light-chain type) with chronic renal failure. Histological examination revealed deposition of a homogeneous substance and crystals in the kidneys and thyroid gland. The homogeneous substance was stained with Congo red after permanganate treatment but did no...

journal_title：Archives of pathology & laboratory medicine

authors： Hirota S,Miyamoto M,Kasugai T,Kitamura Y,Morimura Y

更新日期：1990-04-01 00:00:00

abstract：CONTEXT.—:Atypical ductal hyperplasia (ADH) is a challenging diagnosis defined by cytologic and architectural features that carries an increased risk of subsequent carcinoma when diagnosed in isolation. In addition, ADH may secondarily involve benign breast lesions, wherein it carries variable clinical significance. O...

journal_title：Archives of pathology & laboratory medicine

authors： East EG,Carter CS,Kleer CG

更新日期：2018-10-01 00:00:00

abstract：:Benign clear cell ("sugar") tumor is a rare and most unusual pulmonary neoplasm. Although several reports in the literature have focused on the ultrastructural features of benign clear cell tumor, only a few cases have been formally studied by immunochemistry. Using a broad panel of polyclonal and monoclonal antibodie...

journal_title：Archives of pathology & laboratory medicine

authors： Gal AA,Koss MN,Hochholzer L,Chejfec G

更新日期：1991-10-01 00:00:00

abstract：CONTEXT:It is recommended that hemoglobin (Hb) A1c (Hb A1c) not be used to assess average glycemia in patients who have altered red blood cell life span. OBJECTIVE:To investigate the frequency of reporting an Hb A1c value for Hb variant samples that do not include Hb A. DESIGN:Hb A1c samples (n = 500) were procured a...

journal_title：Archives of pathology & laboratory medicine

authors： Rhea JM,Koch D,Ritchie J,Singh HV,Young AN,Burgess T,Molinaro RJ

更新日期：2013-12-01 00:00:00

abstract：:We describe the clinical, radiologic, and pathologic features of four cases of intraosseous lipoma. The patients ranged in age from 37 to 48 years, and three of them were men. Three patients presented with pain; in the fourth patient, the lesion was discovered incidentally. The involved bones were distal radius (in on...

journal_title：Archives of pathology & laboratory medicine

authors： Barcelo M,Pathria MN,Abdul-Karim FW

更新日期：1992-09-01 00:00:00

abstract：:Glomus tumor is a benign mesenchymal neoplasm comprising less than 2% of soft tissue tumors. It is composed of cells resembling modified smooth muscle cells of the normal glomus body. The glomus body, a thermoregulator, is a specialized form of arteriovenous anastomosis localized in dermal and precoccygeal soft tissue...

journal_title：Archives of pathology & laboratory medicine

authors： Gombos Z,Zhang PJ

更新日期：2008-09-01 00:00:00

abstract：:A premature male neonate, born at the 25th gestational week, developed pneumonia six days after delivery and died. Postmortem examination of the lungs revealed giant cell pneumonia with intranuclear inclusion bodies; varicella zoster infection was confirmed by immunoperoxidase stain using monoclonal antibody to varice...

journal_title：Archives of pathology & laboratory medicine

authors： Saito F,Yutani C,Imakita M,Ishibashi-Ueda H,Kanzaki T,Chiba Y

更新日期：1989-02-01 00:00:00

abstract：:Primary germinal tumors of the mediastinum are very rare. We studied a 67-year-old man with a primary embryonal carcinoma and choriocarcinoma of the mediastinum. To our knowledge, this is the oldest patient described as having this lesion. The diagnosis of primary germinal tumor of the mediastinum should not be made u...

journal_title：Archives of pathology & laboratory medicine

authors： Knapp RH,Fritz SR,Reiman HM

更新日期：1982-10-01 00:00:00

abstract：CONTEXT:- Different types of mature B-cell lymphomas, including plasma cell neoplasms, exhibit distinct immunohistochemical profiles, which enable them to be correctly diagnosed. However, except for rare examples of lymphoma-specific immunohistochemistry, such as cyclin D1 in mantle cell lymphoma and annexin A1 in hair...

journal_title：Archives of pathology & laboratory medicine

authors： Wang HY,Zu Y

更新日期：2017-09-01 00:00:00

abstract：CONTEXT:The unprecedented advances in cancer genetics and genomics are rapidly affecting clinical management and diagnostics in solid tumor oncology. Molecular diagnostics is now an integral part of routine clinical management in patients with lung, colon, and breast cancer. In sharp contrast, molecular biomarkers have...

journal_title：Archives of pathology & laboratory medicine

authors： Netto GJ,Cheng L

更新日期：2012-04-01 00:00:00

abstract：CONTEXT:Case reports have described detection of candidemia by examination of peripheral blood smears. It is unclear whether this method has wider applicability for early detection of fungemia. OBJECTIVE:To determine the sensitivity of smear review for detecting candidemia. DESIGN:Normal and cytopenic blood was spike...

journal_title：Archives of pathology & laboratory medicine

authors： Branda JA,Ferraro MJ,Kratz A

更新日期：2007-01-01 00:00:00

abstract：CONTEXT.—:Squamous lesions of the esophagus encompass a spectrum of disorders ranging from reactive changes and benign papilloma to squamous dysplasia and squamous cell carcinoma, which may pose diagnostic challenges especially in superficial biopsies. OBJECTIVE.—:To provide a review on the typical features of squamou...

journal_title：Archives of pathology & laboratory medicine

authors： Savant D,Zhang Q,Yang Z

更新日期：2020-04-09 00:00:00

abstract：CONTEXT:Correct diagnosis of the tissue origin of a metastatic cancer is the first step in disease management, but it is frequently difficult using standard pathologic methods. Microarray-based gene expression profiling has shown great promise as a new tool to address this challenge. OBJECTIVE:Adoption of microarray t...

journal_title：Archives of pathology & laboratory medicine

authors： Ma XJ,Patel R,Wang X,Salunga R,Murage J,Desai R,Tuggle JT,Wang W,Chu S,Stecker K,Raja R,Robin H,Moore M,Baunoch D,Sgroi D,Erlander M

更新日期：2006-04-01 00:00:00