Cis- and trans-conformations for peroxynitrite anions.

abstract：:Microperoxidase 8 (MP8) is able to react with alkyl- and aryl-isonitriles (RNC) both in its reduced and oxidized states, to form MP8Fe(II)- and MP8Fe(III)-CNR complexes. The coordination and spin states of these complexes have been fully characterized by UV-visible and resonance Raman spectroscopies. Both MP8Fe(II)- a...

journal_title：Journal of inorganic biochemistry

authors： Ricoux R,Lecomte S,Policar C,Boucher JL,Mahy JP

更新日期：2005-05-01 00:00:00

abstract：:The bacterial CopC family of proteins are periplasmic copper binding proteins that act in copper detoxification. These proteins contain Cu(I) and/or Cu(II) binding sites, with the family that binds Cu(II) only the most prevalent, based on sequence analyses. Here we present three crystal structures of the CopC protein ...

journal_title：Journal of inorganic biochemistry

authors： Udagedara SR,Wijekoon CJK,Xiao Z,Wedd AG,Maher MJ

更新日期：2019-06-01 00:00:00

abstract：:Aiming to investigate the use of tridentate ligands to develop new bireductively activated prodrugs, two N(2)O-donor ligands (HL1: [(2-hydroxybenzyl)(2-(imidazol-2-yl)ethyl)]amine; and HL2: [(2-hydroxybenzyl)(2-(pyridil-2-yl)ethyl]amine) were used to synthesize new Co(III) complexes, 1 and 2. Both complexes were chara...

journal_title：Journal of inorganic biochemistry

authors： Souza ET,Castro LC,Castro FA,do Canto Visentin L,Pinheiro CB,Pereira MD,de Paula Machado S,Scarpellini M

更新日期：2009-10-01 00:00:00

abstract：:Effects of the administration of trivalent chromium (Cr(III)) to mice and the activation of carbon tetrachloride (CCl4) to form trichloromethyl radicals (.CCl3) in the liver were studied. The lipid peroxidation in liver microsomes induced in vitro by CCl4 in the presence of NADPH was decreased by the preadministration...

journal_title：Journal of inorganic biochemistry

authors： Tezuka M,Ishii S,Okada S

更新日期：1991-12-01 00:00:00

abstract：:The inhibitory effect of Cu2+, Mn2+, Co2+, and I- on naproxen-induced photohemolysis was investigated. In order to better understand this effect, these ions were also tested for lipid peroxidation and protein crosslinking, which are among the main processes involved in erythrocyte membrane damage. The overall results ...

journal_title：Journal of inorganic biochemistry

authors： Giuffrida S,De Guidi G,Miano P,Sortino S,Condorelli G,Costanzo LL

更新日期：1996-09-01 00:00:00

abstract：:Reduced azurin reacts with the resting, oxidized cytochrome c peroxidase of Pseudomonas aeruginosa to yield time courses observed at 420 nm, which consist of the sum of two exponential processes. Each process exhibits a hyperbolic dependence of the observed rate constant on the reduced azurin concentration. The fracti...

journal_title：Journal of inorganic biochemistry

authors： Brittain T,Greenwood C

更新日期：1992-10-01 00:00:00

abstract：:In order to investigate the low-dose long-term Cr(VI) action on antioxidant enzymes in cultured mammalian cells we estimated the activity of glutathione dependent antioxidant enzymes, catalase and superoxide dismutase (SOD) under various chromium concentrations in human epithelial-like L-41 cells. The long-term action...

journal_title：Journal of inorganic biochemistry

authors： Asatiani N,Sapojnikova N,Abuladze M,Kartvelishvili T,Kulikova N,Kiziria E,Namchevadze E,Holman HY

更新日期：2004-03-01 00:00:00

abstract：:L-Cysteinatogold(I) was prepared by the reaction of L-cysteine with KAuBr4 in acidic media and its solubility determined from pH 4 to 10. The solubility at pH 7.4 and 37 degrees C is 1 microM. In the presence of excess cysteine, the solubility increases because of formation of bis(L-cysteinato)gold(I). The equilibrium...

journal_title：Journal of inorganic biochemistry

authors： Shaw CF 3rd,Schmitz G,Thompson HO,Witkiewicz P

更新日期：1979-07-01 00:00:00

abstract：:Nickel-containing carbon monoxide dehydrogenases, acetyl-CoA synthases, nickel-iron hydrogenases, and diron hydrogenases are distinct metalloenzymes yet they share a number of important characteristics. All are O(2)-sensitive, with active-sites composed of iron and/or nickel ions coordinated primarily by sulfur ligand...

journal_title：Journal of inorganic biochemistry

authors： Lindahl PA

更新日期：2012-01-01 00:00:00

abstract：:The reactions of Fe(II)EDTA, Fe(II)DTPA, and Fe(II)HEDTA with hydrogen peroxide near neutral pH have been investigated. All these reactions have been assumed to proceed through an active intermediate, I1, (Formula: see text) where pac is one of the three polyaminocarboxylates mentioned above. I1, whether .OH radical o...

journal_title：Journal of inorganic biochemistry

authors： Rush JD,Koppenol WH

更新日期：1987-03-01 00:00:00

abstract：:Carboxypeptidase A-catalyzed hydrolysis of peptides and depsipeptides is competitively inhibited by N-(1-carboxy-5-t-butyloxycarbonylaminopentyl)-L-phenylalanine (Boc-CA-Phe, Ki = 1.3 microM) and the angiotensin converting enzyme inhibitor, N-(1-carboxy-5-carbobenzoxyaminopentyl)-glycyl-L-phenylalanine (Z-CA-Gly-Phe, ...

journal_title：Journal of inorganic biochemistry

authors： Martin MT,Holmquist B,Riordan JF

更新日期：1989-05-01 00:00:00

abstract：:The kinetics of reduction of a peroxidatically active intermediate (formed by reaction of deuteroferriheme with hydrogen peroxide) by phenol and a series of substituted phenols have been studied by stopped-flow spectrophotometry. The complex effects of varying heme concentration have been interpreted in terms of the f...

journal_title：Journal of inorganic biochemistry

authors： Jones P,Mantle D,Wilson I

更新日期：1982-12-01 00:00:00

abstract：:Evidence is growing that metabolites of Cr(III) dietary supplements are partially oxidized to carcinogenic Cr(VI) and Cr(V) in vivo. Hence, we examined oxidations of Cr(III) peptide (triglycine, tetraglycine and pentaglycine) complexes to Cr(VI) and Cr(V) by PbO2 at 37°C and physiological pH values between 3.85 and 7....

journal_title：Journal of inorganic biochemistry

authors： Headlam HA,Lay PA

更新日期：2016-09-01 00:00:00

abstract：:Imidazole glycerol phosphate dehydratase (IGPD) catalyses the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, an important late step in the biosynthesis of histidine. IGPD, isolated as a low molecular weight and inactive apo-form, assembles with specific divalent metal cations to form a cata...

journal_title：Journal of inorganic biochemistry

authors： Petersen J,Hawkes TR,Lowe DJ

更新日期：2000-05-30 00:00:00

abstract：:In the presence of magnesium, enolase catalyzes the dehydration of 2-phospho-d-glycerate (PGA) to phosphoenolpyruvate (PEP) in glycolysis and the reverse reaction in gluconeogensis at comparable rates. The structure of human neuron specific enolase (hNSE) crystals soaked in PGA showed that the enzyme is active in the ...

journal_title：Journal of inorganic biochemistry

authors： Qin J,Chai G,Brewer JM,Lovelace LL,Lebioda L

更新日期：2012-06-01 00:00:00

abstract：:Manganese peroxidase (MnP) is an extracellular heme enzyme produced by the lignin-degrading white-rot fungus Phanerochaete chrysosporium. MnP catalyzes the peroxide-dependent oxidation of Mn(II) to Mn(III). The Mn(III) is released from the enzyme in complex with oxalate, enabling the oxalate-Mn(III) complex to serve a...

journal_title：Journal of inorganic biochemistry

authors： Sundaramoorthy M,Gold MH,Poulos TL

更新日期：2010-06-01 00:00:00

abstract：:Oxaliplatin-based chemotherapy is the mainstay for the treatment of advanced colorectal cancer. Copper transporter proteins have been implicated in the transport of platinum-based anticancer drugs, but their expression in human colorectal cancer cell lines and roles in controlling their sensitivity to oxaliplatin are ...

journal_title：Journal of inorganic biochemistry

authors： Cui H,Zhang AJ,McKeage MJ,Nott LM,Geraghty D,Guven N,Liu JJ

更新日期：2017-12-01 00:00:00

abstract：:Horse spleen ferritin (HoSF) reconstituted with small iron cores ranging in size from 8 to 500 iron atoms was studied by magnetic susceptibility and pH measurements to determine when the added Fe3+ begins to aggregate and form antiferromagnetically coupled clusters and also to determine the hydrolytic state of the iro...

journal_title：Journal of inorganic biochemistry

authors： Hilty S,Webb B,Frankel RB,Watt GD

更新日期：1994-11-15 00:00:00

abstract：:Signal transduction in plants determines their successful adaptation to diverse stress factors. Our group employed suspension cells to study the phosphoinositide pathway, which is triggered by aluminium stress. We investigated about members of the PI-specific phospholipase C (PLC) family and evaluated their transcript...

journal_title：Journal of inorganic biochemistry

authors： González-Mendoza VM,Sánchez-Sandoval ME,Munnik T,Hernández-Sotomayor SMT

更新日期：2020-03-01 00:00:00

abstract：:Aluminium chemistry has features in common with two other groups of elements: (1) divalent magnesium and calcium, and (2) trivalent chromium and iron. The essential differences between the first group and aluminium are explored and it is shown that the much higher acidity of aluminium makes it such a powerful competit...

journal_title：Journal of inorganic biochemistry

authors： Williams RJ

更新日期：1999-08-30 00:00:00

abstract：:DNA condensation induced by a pair of heptameric La(III) helical enantiomers M-[La7(S-L)6(CO3)(NO3)6(OCH3)(CH3OH)7]·2CH3OH·5H2O and P-[La7(R-L)6(CO3)(NO3)6(OCH3)(CH3OH)5(H2O)2]·2CH3OH·4H2O (M-La and P-La, L=2-(2-hydroxybenzylamino)-3-carbamoylpropanoic acid) has been investigated by UV/vis spectroscopy, fluorescence s...

journal_title：Journal of inorganic biochemistry

authors： Bao FF,Xu XX,Zhou W,Pang CY,Li Z,Gu ZG

更新日期：2014-09-01 00:00:00

abstract：:Nitroxyl (HNO) has gained interest as a potential treatment of congestive heart failure through the ability of the HNO donor, Angeli's salt (AS), to evoke positive inotropic effects in canine cardiac muscle. The release of nitrite during decomposition limits the use of AS requiring other HNO sources. Acyloxy nitroso c...

journal_title：Journal of inorganic biochemistry

authors： DuMond JF,Wright MW,King SB

更新日期：2013-01-01 00:00:00

abstract：:Heme oxygenase (HO) catalyses the degradation of heme to biliverdin, carbon monoxide (CO) and ferrous iron via three successive monooxygenase reactions, using electrons provided by NADPH-cytochrome P450 reductase (CPR) and oxygen molecules. For cleavage of the oxaporphyrin ring of ferrous α-verdoheme, an intermediate ...

journal_title：Journal of inorganic biochemistry

authors： Sato H,Higashimoto Y,Sakamoto H,Sugishima M,Shimokawa C,Harada J,Palmer G,Noguchi M

更新日期：2011-02-01 00:00:00

abstract：:The conformation of poly[d(T-G).d(C-A)] in aqueous solution (0.1 M NaClO4, 5 mM cacodylic acid buffer, pH 6.9) was studied by circular dichroism (CD) spectroscopy in the ultraviolet. The conformation of the polynucleotide, as reflected by its chiroptical signature, changes in a highly cooperative fashion in the presen...

journal_title：Journal of inorganic biochemistry

authors： Gruenwedel DW,Cruikshank MK

更新日期：1991-07-01 00:00:00

abstract：:In a quest for more effective radiopharmaceuticals for pain palliation of metastatic bone cancer, this paper relates results obtained with 166Ho and 153Sm complexed to the bone seeking phosphonate, N,N-dimethylenephosphonate-1-hydroxy-4-aminopropylidenediphosphonate (APDDMP). APDDMP is synthesised from the known bone ...

journal_title：Journal of inorganic biochemistry

authors： Zeevaart JR,Jarvis NV,Louw WK,Jackson GE

更新日期：2001-01-01 00:00:00

abstract：:One-electron reduction and oxidation induced by vanadium complexes are demonstrated to be useful in oxidative and reductive transformations of carbonyl compounds. The redox interaction between vanadium complexes and redox-active ligands is achieved with coenzyme PQQ and polyanilines that afford the corresponding redox...

journal_title：Journal of inorganic biochemistry

authors： Hirao T

更新日期：2000-05-30 00:00:00

abstract：:Gold(III) complexes bearing bidentate ligands based on the 1,10-phenanthroline and 2,2'-bipyridine scaffolds have shown promising anticancer activity against a variety of tumor cell lines. In particular, our laboratory has previously found that a pseudo five coordinate gold(III) complex possessing the 2,9-di-sec-butyl...

journal_title：Journal of inorganic biochemistry

authors： Olsen PM,Ruiz C,Lussier D,Le BK,Angel N,Smith M,Hwang CB,Khatib R,Jenkins J,Adams K,Getcher J,Tham F,Chen ZG,Wilson EH,Eichler JF

更新日期：2014-12-01 00:00:00

abstract：:Up-regulated expression of amyloid precursor protein (APP) occurs early in the cascade of events that leads to amyloid plaque formation in the human brain. APP gene up-regulation, mediated by activated NF-kappaB, is a response to stress from nM concentrations of aluminum ions, aluminum-disregulated iron ions, reactive...

journal_title：Journal of inorganic biochemistry

authors： Walton JR,Wang MX

更新日期：2009-11-01 00:00:00

abstract：:The complexation between tin(II) ion and glycine was studied in 0.15 mol/dm3 NaCl medium at 310 K using potentiometric glass electrode titrations. In the pH range 1.1-4.5 and concentration range of the tin(II) between 0.2 and 5.0 mmol/dm3, with variable glycine-to-tin molar ratio up to 10:1, the experimental data were...

journal_title：Journal of inorganic biochemistry

authors： Djurdjevic P,Djokic D

更新日期：1996-04-01 00:00:00

abstract：:Aiming at tumor targeting delivery of oxaliplatin using polymer therapy, a new monomeric platinum(II) complex (dach)Pt[HEDM] (dach: trans-(±)-1,2-diaminocyclohexane; HEDM: 2-hydroxyethoxydiethylmalate) was designed to include the antitumor moiety (dach)Pt and HEDM as a linker to the polyphosphazene backbone. This mono...

journal_title：Journal of inorganic biochemistry

authors： Avaji PG,Joo HI,Park JH,Park KS,Jun YJ,Lee HJ,Sohn YS

更新日期：2014-11-01 00:00:00