Abstract：
OBJECTIVES:To determine whether exercise-induced silent ischemia in older master athletes following a 3-month period of deconditioning is a predictor of future cardiovascular events. DESIGN:A longitudinal study of a cohort of master athletes. SETTING:The Geriatric Research Education and Clinical Center (GRECC), Baltimore VA Medical Center, Baltimore, Maryland. PARTICIPANTS:Ten older (59 +/- 8 years, mean +/- SD), highly conditioned (maximal aerobic capacity VO2max 50 +/- 5 mL/kg/min), aerobically trained athletes. INTERVENTION:Five to eight years of longitudinal follow-up of athletes who had previously participated in a 3-month-long detraining intervention. MEASUREMENTS:At baseline, all 10 athletes had their history taken and underwent physical examinations, metabolic testing, electrocardiogram at rest, exercise treadmill tests, exercise thallium scintigrams, and exercise multigated acquisition scans. After 3 months of deconditioning, they had repeat maximal exercise stress tests. After 5 to 8 years of follow-up, they were re-evaluated, including history and physical examination and measurement of their VO2max. RESULT:All 10 master athletes had normal studies at baseline. At the end of 3 months of detraining, three of these athletes had exercise-induced silent ischemia, which disappeared after retraining in two subjects and persisted at a higher heart rate in one subject. Over a 5- to 8-year period of observation, two of these three athletes with silent ischemia experienced major cardiac events (sudden death, cardiac bypass surgery). The other seven athletes did not have any cardiovascular events. CONCLUSIONS:Exercise-induced silent ischemia after a short period of detraining in highly trained older athletes may be a predictor of future cardiac events. A study with a larger cohort is warranted.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Begum S,Katzel LIdoi
10.1111/j.1532-5415.2000.tb04722.xsubject
Has Abstractpub_date
2000-06-01 00:00:00pages
647-50issue
6eissn
0002-8614issn
1532-5415journal_volume
48pub_type
杂志文章abstract：OBJECTIVE:To assess the utility of geriatric targeting criteria in predicting survival and health care utilization in a cohort of hospitalized older veterans. DESIGN:A prospective cohort study assessing geriatric targeting criteria, e.g., polypharmacy, falls, or confusion, with respect to adverse outcomes at 12 months...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1996.tb01860.x
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVES:To examine whether hearing acuity correlates with walking ability and whether impaired hearing at baseline predicts new self-reported walking difficulties after 3 years. DESIGN:Prospective follow-up. SETTING:Research laboratory and community. PARTICIPANTS:Four hundred thirty-four women aged 63 to 76. MEA...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02553.x
更新日期：2009-12-01 00:00:00
abstract：:The immune status of 17 healthy individuals 100-103 years of age (centenarians) was investigated. Qualitative values for immunoglobulins IgG, IgM, IgA, and IgE were within normal ranges for subjects more than 60 years of age with the exception of elevated IgM in one individual. Cell marker studies employing a panel of...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1984.tb02021.x
更新日期：1984-04-01 00:00:00
abstract：OBJECTIVES:To determine whether metabolic syndrome is an independent predictor of decline in mobility in an elderly community sample. DESIGN:Biracial community-based prospective cohort study. SETTING:Urban and rural areas of central North Carolina. PARTICIPANTS:One thousand two hundred twenty-nine older African Amer...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.00607.x
更新日期：2006-03-01 00:00:00
abstract：:The objective of this study was to use performance-based measurements to identify, in a population of community-dwelling American Indians aged 55 and older, the prevalence and correlates of lower body functioning. Data were collected as part of a cross-sectional study of disability from members of a tribe in the south...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03869.x
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:To determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus. DESIGN:Controlled clinical trial. SETTING:Primary care clinics of the Durham Veterans Affairs (VA) Medical Center betwe...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1532-5415.2012.04119.x
更新日期：2012-09-01 00:00:00
abstract：:One hundred seventy-one patients, 60 years of age or older with isolated systolic hypertension, were randomly assigned to receive chlorthalidone 12.5, 25.0, or 50.0 mg or placebo once daily for 12 weeks. The majority of the patients receiving chlorthalidone 12.5 mg achieved therapeutic success with no clinically signi...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.1986.tb04203.x
更新日期：1986-03-01 00:00:00
abstract：OBJECTIVES:To study the distribution of adiponectin isoforms in a group of very old patients. DESIGN:Cross-sectional. SETTING:Geriatric ambulatory clinic of the Department of Medicine at Policlinico "Tor Vergata." PARTICIPANTS:One hundred eight elderly adults (mean age 85.0+/-3.2) with or without a history of a prev...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02773.x
更新日期：2010-04-01 00:00:00
abstract：:Oral temperature has long been used as a basis for clinical decisions. The ingestion of cold liquids such as iced water, which are frequently found at patients' bedsides or in clinic waiting areas, has been believed to potentially lower oral temperature readings. The degree and duration of this effect, however, has no...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1986.tb04245.x
更新日期：1986-07-01 00:00:00
abstract：:Two cases are reported of left atrial myxoma in elderly patients, diagnosed by combined M-mode and bidimensional echocardiography. One patient was an 80-year-old man presenting with typical signs of mitral obstruction by an atrial tumor. His symptoms were erroneously attributed to chronic bronchitis until an echocardi...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1981.tb01748.x
更新日期：1981-10-01 00:00:00
abstract：OBJECTIVES:To determine whether the occurrence of depression predicts physical disability in older people. DESIGN:A longitudinal epidemiological study with a follow-up of 5 years. SETTING:A comparison between depressed and nondepressed participants. PARTICIPANTS:The series consisted of the persons who participated i...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.4930290.x
更新日期：2001-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Mammographic screening for breast cancer is of uncertain clinical benefit for women 75 years of age and older. Some have argued against instituting routine screening in this age group, noting that disability and shorter life expectancy may diminish the desirability and cost-effectiveness of sc...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1998.tb02746.x
更新日期：1998-08-01 00:00:00
abstract：:The aim of this study was to evaluate the effect of a geriatric-anesthesiologic intervention program for the prevention and treatment of acute confusional states (ACS) in elderly patients treated for femoral neck fractures. The intervention program was based on the results of previous prospective studies in similar pa...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1991.tb03618.x
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVES:To examine associations between inflammation and physical function and potential mediation by white matter hyperintensities (WMHs) in African Americans (AAs) and European Americans (EAs). DESIGN:Cross-sectional analysis using linear and logistic models with generalized estimating equations to account for fa...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14229
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVES:To assess clinical outcomes and identify risk factors for mortality in older adults with Staphylococcus aureus bloodstream infection (SAB). DESIGN:Retrospective review. SETTING:University of Michigan Health System, Ann Arbor. PARTICIPANTS:All patients aged 80 and older with SAB between January 2004 and Ju...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02666.x
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVES:To investigate statin use and pain in people with cancer aged 70 to 79 and 80 and older. DESIGN:Cross-sectional. SETTING:Medical oncology outpatient clinic at the Royal Adelaide Hospital. PARTICIPANTS:Individuals aged 70 and older who presented consecutively between January 2009 and June 2010 (n = 385), o...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13051
更新日期：2014-10-01 00:00:00
abstract：:Delirium is a common and serious condition that is underrecognized in older adults in a variety of healthcare settings. It is poorly recognized because of deficiencies in provider knowledge and its atypical presentation. Early recognition of delirium is warranted to better manage the disease and prevent the adverse ou...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/jgs.12522
更新日期：2013-11-01 00:00:00
abstract：:Patients with diabetes mellitus and an underlying mixed axonal and demyelinating polyneuropathy are particularly prone to compression neuropathies with consequent axonal degeneration and a poor prognosis for recovery. This hazard should be taken into account whenever a prolonged surgical procedure is contemplated. An ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1980.tb00515.x
更新日期：1980-04-01 00:00:00
abstract：OBJECTIVES:To determine the independent prognostic effect of seven potential frailty criteria, including five from the Fried phenotype, on several adverse outcomes. DESIGN:Prospective cohort study. SETTING:Greater New Haven, Connecticut. PARTICIPANTS:Seven hundred fifty-four initially nondisabled, community-living p...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2008.02008.x
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:To determine the validity of the Minimum Data Set (MDS). DESIGN:MDS domain scores were correlated with a variety of independently obtained measures of basic behavioral and mental health functions of 513 nursing home residents. SETTING:All participants were residents of the Philadelphia Geriatric Center. PA...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1998.tb03809.x
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:To examine the effects of caring for a spouse with dementia on the caregiver's risk for incident dementia. DESIGN:Population-based study of incident dementia in spouses of persons with dementia. SETTING:Rural county in northern Utah. PARTICIPANTS:Two thousand four hundred forty-two subjects (1,221 married...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02806.x
更新日期：2010-05-01 00:00:00
abstract：:Although the field of frailty research has expanded rapidly, it is still a nascent concept within the clinical specialties. Frailty, conceptualized as greater vulnerability to stressors because of significant depletion of physiological reserves, predicts poorer outcomes in several medical specialties, including cardio...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.14902
更新日期：2017-10-01 00:00:00
abstract：:The hypochondriacal attitudes of 53 aged community residents were studied. No significant correlations were found with situational stress, sex, or ethnicity (English-speaking vs Spanish-speaking). The levels of hypochondriasis appeared to be inversely related to self-evaluation of memory ability. There was no indicati...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1981.tb02392.x
更新日期：1981-01-01 00:00:00
abstract：:The reports on 72 of 190 accidents occurring among 189 nursing home residents during a 3-month period were drawn at random and reviewed. The majority of the accidents were falls, either major or minor. Personal data on the residents included age, sex, mental status, number of diseases, and number of drugs administered...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1978.tb05391.x
更新日期：1978-09-01 00:00:00
abstract：:Neurotoxic effects of habitual alcohol consumption were investigated by correlating the subjects' estimates of abstinence or frequency and amount of alcohol consumed with measurements of gray matter blood flow utilizing the 133Xe inhalation method. Two hundred and twenty-two subjects were studied, including 136 health...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1983.tb02198.x
更新日期：1983-09-01 00:00:00
abstract：:Dissemination of cutting-edge geriatrics-focused research is essential for academic geriatrics researchers, clinicians, and older adults and their caregivers. Social media channels, such as Twitter, provide a means of quickly reaching a wide array of users, globally. Besides standard tweets with links to research arti...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15853
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVES:To determine the effect of age on patterns of infection and on outcomes in individuals with infection. DESIGN:Analysis of data from an international, observational, point-prevalence study: Extended Prevalence of Infection in Intensive Care (EPIC II). SETTING:Intensive care units (ICUs; N=1,265) in 75 count...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/jgs.12544
更新日期：2013-12-01 00:00:00
abstract：:Cognitive impairment in old age is one of the most important topics in modern geriatrics. This article discusses the historical dimensions of this phenomenon. To this end, a number of primary sources ranging from antiquity to the modern era are evaluated. Although a physiology and pathology of old age were conceptuali...
journal_title：Journal of the American Geriatrics Society
pub_type： 历史文章,杂志文章
doi：10.1111/j.1532-5415.2005.53558.x
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVES:To compare the trajectories of motor and cognitive decline in older adults who progress to dementia with the trajectories of those who do not. To evaluate the added value of measuring motor and cognitive decline longitudinally versus cross-sectionally for predicting dementia. DESIGN:Prospective cohort study...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15341
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:To assess the physical and mental health status of older long-term cancer survivors. DESIGN:Cohort study using propensity score methods to control for baseline differences between cancer survivors and controls. SETTING:General community population in the United States. PARTICIPANTS:Nine hundred sixty-four...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.00507.x
更新日期：2005-12-01 00:00:00
