Abstract:
:A series of N6,2-disubstituted adenosine analogues have been synthesized and their functional activity measured against A2a and A1 receptors. Examples of compounds with both a lipophilic N6-substituent and amino-functionalized 2-position were highly active at the A2a receptor on the human neutrophil.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Keeling SE,Albinson FD,Ayres BE,Butchers PR,Chambers CL,Cherry PC,Ellis F,Ewan GB,Gregson M,Knight J,Mills K,Ravenscroft P,Reynolds LH,Sanjar S,Sheehan MJdoi
10.1016/s0960-894x(00)00017-2subject
Has Abstractpub_date
2000-02-21 00:00:00pages
403-6issue
4eissn
0960-894Xissn
1464-3405pii
S0960-894X(00)00017-2journal_volume
10pub_type
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