Sevoflurane, but not propofol, significantly prolongs the Q-T interval.

abstract：UNLABELLED:Because inhibition of voltage-dependent Ca(2+) channels can be a mechanism underlying general anesthesia, we examined sensitivities to propofol and halothane in mice lacking the R-type (Ca(v)2.3) channel widely expressed in neurons. Sleep time after propofol injection (26 mg/kg IV) and halothane MAC(RR) and ...

journal_title：Anesthesia and analgesia

authors： Takei T,Saegusa H,Zong S,Murakoshi T,Makita K,Tanabe T

更新日期：2003-07-01 00:00:00

abstract：:The effect of the alpha 2-agonist dexmedetomidine on the cerebral blood flow (CBF) and the metabolic rate for oxygen was studied by a sagittal sinus outflow technique in dogs during halothane anesthesia. Dexmedetomidine was given in a dose (10 micrograms/kg) reported to reduce the anesthetic requirement of halothane b...

journal_title：Anesthesia and analgesia

authors： Karlsson BR,Forsman M,Roald OK,Heier MS,Steen PA

更新日期：1990-08-01 00:00:00

abstract：:Pneumothorax can develop during laparoscopy, particularly during laparoscopic fundoplication, since the left parietal pleura is exposed and can be torn during dissection in the diaphragmatic hiatus. Such an event will result in specific pathophysiologic changes, since CO2, under pressure in the abdominal cavity, will ...

journal_title：Anesthesia and analgesia

authors： Joris JL,Chiche JD,Lamy ML

更新日期：1995-11-01 00:00:00

abstract：:This investigation examined the role of myocardial adenosine triphosphate-regulated potassium (KATP) channels in isoflurane-induced enhancement of myocardial function after reversible tissue injury produced by a 15-min left anterior descending coronary artery occlusion (LAD) and reperfusion. Dogs (n = 14) were chronic...

journal_title：Anesthesia and analgesia

authors： Kersten JR,Lowe D,Hettrick DA,Pagel PS,Gross GJ,Warltier DC

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:We determined whether whole blood impedance aggregometry using the Multiplate detects the effects of antiplatelet drugs as reliably as does classical light transmission aggregometry (LTA) or the platelet function analyzer PFA-100(R). METHODS:Multiplate (M) assays, measuring changes in electrical resistance ...

journal_title：Anesthesia and analgesia

authors： Velik-Salchner C,Maier S,Innerhofer P,Streif W,Klingler A,Kolbitsch C,Fries D

更新日期：2008-12-01 00:00:00

abstract：:The purpose of this study was to determine if the addition of sufentanil would improve the quality of analgesia obtained with 0.125% epidural bupivacaine infusions given to women in active labor. Forty healthy laboring women were randomly assigned to two equal groups. Group 1 had epidural analgesia instituted with the...

journal_title：Anesthesia and analgesia

authors： Phillips G

更新日期：1988-05-01 00:00:00

abstract：UNLABELLED:Reports of transient neurological symptoms with the use of subarachnoid lidocaine has generated interest in alternate local anesthetics of intermediate duration, such as mepivacaine. This prospective randomized, double-blinded, dose-response study examined the anesthetic and recovery profiles of 60- and 80-m...

journal_title：Anesthesia and analgesia

authors： Pawlowski J,Sukhani R,Pappas AL,Kim KM,Lurie J,Gunnerson H,Corsino A,Frey K,Tonino P

更新日期：2000-09-01 00:00:00

abstract：:The purpose of this canine study was to examine the cerebral vascular and metabolic effects of adding nitrous oxide to isoflurane from 1.4% expired (1 MAC) up to a concentration giving an isoelectric electroencephalogram (EEG). Cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) were determined us...

journal_title：Anesthesia and analgesia

authors： Roald OK,Forsman M,Heier MS,Steen PA

更新日期：1991-01-01 00:00:00

abstract：:Spontaneous or evoked electrical brain activity is increasingly used to monitor general anesthesia. Previous studies investigated the variables from spontaneous electroencephalogram (EEG), acoustic (AEP), or somatosensory evoked potentials (SSEP). But, by monitoring them separately, the available information from simu...

journal_title：Anesthesia and analgesia

authors： Jeleazcov C,Schneider G,Daunderer M,Scheller B,Schüttler J,Schwilden H

更新日期：2006-10-01 00:00:00

abstract：:The influence of preoxygenation in the supine (n = 10) versus the 45 degrees head-up (n = 10) position on the duration of apnea leading to a decrease in arterial oxygen saturation to 95%, as monitored by pulse oximetry, was investigated in 20 women undergoing elective cesarean section at term of pregnancy. The results...

journal_title：Anesthesia and analgesia

authors： Baraka AS,Hanna MT,Jabbour SI,Nawfal MF,Sibai AA,Yazbeck VG,Khoury NI,Karam KS

更新日期：1992-11-01 00:00:00

abstract：:We studied the time to postoperative micturition and the duration of analgesia in 82 children aged 6 mo to 10 yr undergoing herniorrhaphy or orchiopexy under general anesthesia with N2O and halothane. All received D5 lactate Ringer's solution equivalent to 6 h maintenance intraoperatively, and oral fluids postoperativ...

journal_title：Anesthesia and analgesia

authors： Fisher QA,McComiskey CM,Hill JL,Spurrier EA,Voigt RE,Savarese AM,Beaver BL,Boltz MG

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Recently, there has been significant focus on the effects of anesthesia on the developing brain. Concern is heightened in children <3 years of age requiring lengthy and/or multiple anesthetics. Hypospadias correction is common in otherwise healthy children and may require both lengthy and repeated anesthetic...

journal_title：Anesthesia and analgesia

authors： Adler AC,Chandrakantan A,Sawires Y,Lee AD,Hart M,Koh CJ,Janzen NK,Austin PF,Andropoulos DB

更新日期：2019-12-09 00:00:00

abstract：UNLABELLED:This study was performed to evaluate the ability of anesthesiologists to differentiate between sevoflurane, a newer, more expensive anesthetic, and halothane. A total of 113 assessments were made by 36 anesthesiologists on 58 children, aged 6 mo to 6 yr, scheduled for bilateral myringotomy and tube placement...

journal_title：Anesthesia and analgesia

authors： Bacher A,Burton AW,Uchida T,Zornow MH

更新日期：1997-12-01 00:00:00

abstract：:During Gram-negative sepsis, endotoxin lipopolysaccharide (LPS) may activate host inflammatory responses, resulting in the systemic inflammatory response syndrome and the adult respiratory distress syndrome. In cell culture systems, LPS activation of cellular responses may be potentiated by plasma proteins. In the iso...

journal_title：Anesthesia and analgesia

authors： Goldsmith JA,Kavanagh BP,Pearl RG

更新日期：1996-08-01 00:00:00

abstract：:Morphine anesthesia is often recommended in patients with reduced cardiac reserve. As the effect of morphine on the balance between myocardial oxygen supply and demand is not well understood, the effect of large doses of morphine (3 mg/kg, subcutaneously) on experimental myocardial infarction size in the rat was evalu...

journal_title：Anesthesia and analgesia

authors： Markiewicz W,Finberg JP,Lichtig C

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Ten to fifteen percent of awake patients develop neurological deficits secondary to cerebral hypoperfusion after carotid artery cross-clamping. The reversal of such deficits by increasing the inspired oxygen fraction (Fio(2)) has been demonstrated, and regional cerebral oxygenation (rSO(2)) has been shown to...

journal_title：Anesthesia and analgesia

authors： Picton P,Chambers J,Shanks A,Dorje P

更新日期：2010-02-01 00:00:00

abstract：:Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradycardia. The aim of our study was to compare hemodynamic and analgesic effects of spinal versus epidural clonidine alone and after repetitive dosing. In a prospective, randomized, double-blind study, we evaluated 40 patients...

journal_title：Anesthesia and analgesia

authors： Klimscha W,Chiari A,Krafft P,Plattner O,Taslimi R,Mayer N,Weinstabl C,Schneider B,Zimpfer M

更新日期：1995-02-01 00:00:00

abstract：:A claim of superiority of one intervention over another often depends naturally on results from several outcomes of interest. For such studies the common practice of making conclusions about individual outcomes in isolation can be problematic. For example, an intervention might be shown to improve one outcome (e.g., p...

journal_title：Anesthesia and analgesia

authors： Mascha EJ,Turan A

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:As orexinergic (OXergic) neurons have been reported to mediate emotional changes, benzodiazepines might interact with OXergic neurons. METHODS:We examined the interactions between OXergic neurons and benzodiazepine receptors in orexin-A (100 nM) and K+ (25 mM)-evoked norepinephrine release from rat cerebroc...

journal_title：Anesthesia and analgesia

authors： He Y,Kudo M,Kudo T,Kushikata T,Li E,Hirota K

更新日期：2007-02-01 00:00:00

abstract：:This consensus statement was commissioned in 2012 by the Board of Directors of the Society for Obstetric Anesthesia and Perinatology to improve maternal resuscitation by providing health care providers critical information (including point-of-care checklists) and operational strategies relevant to maternal cardiac arr...

journal_title：Anesthesia and analgesia

authors： Lipman S,Cohen S,Einav S,Jeejeebhoy F,Mhyre JM,Morrison LJ,Katz V,Tsen LC,Daniels K,Halamek LP,Suresh MS,Arafeh J,Gauthier D,Carvalho JC,Druzin M,Carvalho B,Society for Obstetric Anesthesia and Perinatology.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As part of the Thai Anesthesia Incidents Study of anesthetic adverse outcomes, we evaluated the incidence and factors related to cardiac arrest during spinal anesthesia. METHODS:During a 12-mo period (March 1, 2003, to February 28, 2004), a prospective, multicenter registry of patients receiv...

journal_title：Anesthesia and analgesia

authors： Charuluxananan S,Thienthong S,Rungreungvanich M,Chanchayanon T,Chinachoti T,Kyokong O,Punjasawadwong Y

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS:We used data from a previous multicenter double-...

journal_title：Anesthesia and analgesia

authors： Lopez-Picado A,Albinarrate A,Barrachina B

更新日期：2017-07-01 00:00:00

abstract：:A number of cardiac arrests and severe hypotensive episodes have been witnessed associated with the intravenous infusion of fresh frozen plasma (FFP). To clarify the possible role of hypocalcemia, 28 thermally injured anesthetized pediatric patients with massive blood loss were studied to examine the cardiovascular re...

journal_title：Anesthesia and analgesia

authors： Coté CJ,Drop LJ,Hoaglin DC,Daniels AL,Young ET

更新日期：1988-02-01 00:00:00

abstract：:We studied 49 patients of ASA physical status I to determine cerebral anesthetic concentration on awakening calculated with end-tidal anesthetic concentration, when the end-tidal concentration decreased spontaneously. We also attempted to explain the difference in the average of the bracketing alveolar anesthetic conc...

journal_title：Anesthesia and analgesia

authors： Katoh T,Suguro Y,Kimura T,Ikeda K

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Improved pain control after cesarean delivery remains a challenging objective. Poorly treated acute pain following delivery is associated with an increased risk of chronic pain and depression. This study was conducted to determine whether the addition of systemic acetaminophen and an increased dose of intrat...

journal_title：Anesthesia and analgesia

authors： Booth JL,Harris LC,Eisenach JC,Pan PH

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Neuropathic pain is a result of a primary lesion or dysfunction of the peripheral or central nervous system, and its treatment is challenging. Animal models have been helpful in understanding mechanisms of neuropathic pain and in developing new treatment strategies. In this study, we examined the effect of p...

journal_title：Anesthesia and analgesia

authors： Ozsoylar O,Akçali D,Cizmeci P,Babacan A,Cahana A,Bolay H

更新日期：2008-10-01 00:00:00

abstract：:The onset and intensity of blockade of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine were investigated in a randomized, double-blind study in 26 patients. Control subjects (n = 13) received 20 mL of 1.37% lidocaine (1.5% lidocaine plus 1 mL saline per 10 mL lidocaine) with added 1:200...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Toleikis JR,Dixit P,Goodman I,Hill JA

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

journal_title：Anesthesia and analgesia

authors： Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

更新日期：2018-08-01 00:00:00

abstract：UNLABELLED:Capsaicin can produce a selective and long-lasting neural blockade. Resiniferatoxin (RTX) is an ultrapotent vanilloid agonist with a unique spectrum of activities different from that of capsaicin. We sought to determine whether a single application of RTX to a peripheral nerve could completely prevent the lo...

journal_title：Anesthesia and analgesia

authors： Kissin I,Bright CA,Bradley EL Jr

更新日期：2002-05-01 00:00:00

abstract：:This study reports plasma bupivacaine concentrations in 13 neonates who received lumbar epidural anesthesia during major abdominal surgery. A bolus of 1.8 mg/kg of bupivacaine (2.5 mg/mL) was administered after induction of anesthesia, followed by a continuous infusion of 0.2 mg.kg-1.h-1 (1.25 mg/mL). Plasma concentra...

journal_title：Anesthesia and analgesia

authors： Larsson BA,Lönnqvist PA,Olsson GL

更新日期：1997-03-01 00:00:00