The role of radiotherapy in non-small cell lung cancer.

Abstract:

:Most patients who receive a diagnosis of non-small cell lung cancer (NSCLC) have advanced disease and are not curable with surgery. Developments in the technology of radiation therapy (RT) have contributed to the broad utility of this treatment modality in both a curative and palliative capacity. Many patients at all stages, including those who are medically inoperable, may benefit from RT. Locally advanced NSCLC is treated commonly with combined modality therapy. Novel RT administration schedules and chemotherapy regimens for combined modality therapy are essential for improving the management of NSCLC. Additional benefits can be foreseen as new strategies for patient selection emerge.

journal_name

Chest

journal_title

Chest

authors

Sause WT

doi

10.1378/chest.116.suppl_3.504s

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

504S-508S

issue

6 Suppl

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)30757-1

journal_volume

116

pub_type

杂志文章,评审

相关文献

CHEST文献大全
  • Effect of Age on Phenotype and Outcomes in Pulmonary Arterial Hypertension Trials.

    abstract:BACKGROUND:In recent years, the population of patients with pulmonary arterial hypertension (PAH) has changed dramatically, including more advanced age at diagnosis. We hypothesized that older patients have a distinct clinical profile with different disease characteristics and response to intervention. METHODS:All pre...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2015.11.008

    authors: Rose JA,Cleveland JM,Rao Y,Minai OA,Tonelli AR

    更新日期:2016-05-01 00:00:00

  • Antitussive effect of the GABA-agonist baclofen.

    abstract:BACKGROUND:gamma-Aminobutyric acid (GABA) is a central inhibitory neurotransmitter that also exists in peripheral tissues, including the lung. The GABA-agonist baclofen has been shown, in animal studies, to inhibit cough via a central mechanism, but has not been investigated in humans (to our knowledge). STUDY OBJECTI...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.111.4.996

    authors: Dicpinigaitis PV,Dobkin JB

    更新日期:1997-04-01 00:00:00

  • Symptom perception in pediatric asthma: resistive loading and in vivo assessment compared.

    abstract:BACKGROUND:Inaccurate symptom perception contributes to asthma morbidity and mortality in children and adults. Various methods have been used to quantify perceptual accuracy, including psychophysical (resistive loading) approaches, ratings of dyspnea during induced bronchoconstriction, and in vivo monitoring, but it is...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.06-2140

    authors: Fritz GK,Adams SK,McQuaid EL,Klein R,Kopel S,Nassau J,Mansell A

    更新日期:2007-09-01 00:00:00

  • Bronchiolitis obliterans and Nocardia asteroides infection of the lung.

    abstract::This report describes a patient with right lower lung (RLL) pneumonia of a subacute nature. Sputum and bronchial washings both grew N asteroides. Open lung biopsy showed bronchiolitis obliterans. Both the clinical and radiologic picture dramatically improved during three weeks of treatment with trimethoprim and sulfam...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.6.1107

    authors: Camp M,Mehta JB,Whitson M

    更新日期:1987-12-01 00:00:00

  • Epidemiology and clinicopathology of aortic dissection.

    abstract:STUDY OBJECTIVES:To determine the incidence and mortality as well as to analyze the clinical and pathologic changes of aortic dissection. DESIGN AND SETTING:A population-based longitudinal study over 27 years on a study population of 106,500, including 66 hospitalized and 18 nonhospitalized consecutively observed pati...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.5.1271

    authors: Mészáros I,Mórocz J,Szlávi J,Schmidt J,Tornóci L,Nagy L,Szép L

    更新日期:2000-05-01 00:00:00

  • COPD can mimic the appearance of pneumothorax on thoracic ultrasound.

    abstract:PURPOSES:To determine the diagnostic accuracy of ultrasound in the diagnosis of pneumothorax in patients with COPD with particular regard to false-positive diagnoses. MATERIALS AND METHODS:This was a single-center, prospective, blinded study. Nine patients with pneumothorax, 9 patients with cystic fibrosis, 17 patient...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.3.545

    authors: Slater A,Goodwin M,Anderson KE,Gleeson FV

    更新日期:2006-03-01 00:00:00

  • Air leaks after lobectomy increase the risk of empyema but not of cardiopulmonary complications: a case-matched analysis.

    abstract:PURPOSE:To assess whether the presence and duration of air leaks after lobectomy are associated with an increased incidence of cardiopulmonary complications. METHODS:Propensity score analysis was used on 726 patients undergoing pulmonary lobectomy from 1995 through 2004 to form three well-matched pairs of patients: pa...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.4.1150

    authors: Brunelli A,Xiume F,Al Refai M,Salati M,Marasco R,Sabbatini A

    更新日期:2006-10-01 00:00:00

  • Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma.

    abstract:OBJECTIVES:A fixed combination of long-acting beta(2)-agonists (LABA) plus inhaled corticosteroids (ICS) has never been proven to reduce asthma exacerbations vs ICS alone in children. This 12-month, double-blind, randomized study in 341 children (age range, 4 to 11 years) with asthma uncontrolled on ICS investigated wh...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.130.6.1733

    authors: Bisgaard H,Le Roux P,Bjåmer D,Dymek A,Vermeulen JH,Hultquist C

    更新日期:2006-12-01 00:00:00

  • Bed partners' assessment of nasal continuous positive airway pressure therapy in obstructive sleep apnea.

    abstract:STUDY OBJECTIVE:This study aimed to evaluate the effects of nasal continuous positive airway pressure (nCPAP) therapy on sleep and daytime symptoms of bed partners and patients with obstructive sleep apnea (OSA). DESIGN:A cross-sectional questionnaire survey. SETTING:The sleep laboratory of a university teaching hosp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.5.1261

    authors: Kiely JL,McNicholas WT

    更新日期:1997-05-01 00:00:00

  • Surgical treatment of malignant pleural mesothelioma: a review.

    abstract::Despite many years of clinical research, there is still no effective therapy for malignant pleural mesothelioma (MPM). Untreated, the prognosis is poor, with a median survival of < 1 year. Single-agent or combination chemotherapy as well as radiotherapy have not shown persistent improvements in response or survival. I...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.123.2.551

    authors: van Ruth S,Baas P,Zoetmulder FA

    更新日期:2003-02-01 00:00:00

  • Spontaneous partial expectoration of an endobronchial carcinoid.

    abstract::Typical pulmonary carcinoid tumors often present as proximal endobronchial masses discovered during the evaluation of cough and/or hemoptysis. We present a case of a carcinoid tumor that presented with spontaneous partial expectoration. A review of the literature revealed 16 cases of expectoration of fragments from va...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.2.595

    authors: Kelly WF,Crawley EA,Vick DJ,Hurwitz KM

    更新日期:1999-02-01 00:00:00

  • Etiology and diagnosis of pneumonia requiring ICU admission.

    abstract::The spectrum of pathogens and the microbiologic investigations used to obtain a diagnosis in 178 patients with severe pneumonia (88 percent requiring intermittent positive-pressure ventilation) are reviewed. Ninety-five patients had primary pneumonia, 31 had nosocomial pneumonia, 24 were immunocompromised patients, an...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.1.199

    authors: Potgieter PD,Hammond JM

    更新日期:1992-01-01 00:00:00

  • Aortic intramural hematoma: an increasingly recognized and potentially fatal entity.

    abstract::Aortic intramural hematoma (IMH) is related to but is pathologically distinct from aortic dissection. In this potentially lethal entity, there is hemorrhage into the aortic media in the absence of an intimal tear. Although intimal disruption is not present, the prognosis is similar to that of classic aortic dissection...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.120.4.1340

    authors: Sawhney NS,DeMaria AN,Blanchard DG

    更新日期:2001-10-01 00:00:00

  • Angiotensin II Infusion for Shock: A Multicenter Study of Postmarketing Use.

    abstract:BACKGROUND:Vasodilatory shock refractory to catecholamine vasopressors and arginine vasopressin is highly morbid and responsible for significant mortality. Synthetic angiotensin II is a potent vasoconstrictor that may be suitable for use in these patients. RESEARCH QUESTION:What is the safety and effectiveness of angi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.08.2074

    authors: Wieruszewski PM,Wittwer ED,Kashani KB,Brown DR,Butler SO,Clark AM,Cooper CJ,Davison DL,Gajic O,Gunnerson KJ,Tendler R,Mara KC,Barreto EF

    更新日期:2020-08-31 00:00:00

  • The prevalence of exercise-induced bronchospasm among US Army recruits and its effects on physical performance.

    abstract:STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seve...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.6.1676

    authors: Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CM

    更新日期:2001-06-01 00:00:00

  • Computed chest tomography in the evaluation of hemoptysis. Impact on diagnosis and treatment.

    abstract::The results of computed chest tomograms (CT) and chest roentgenograms (CR) were compared in 32 patients who presented with hemoptysis. The CT demonstrated roentgenographic abnormalities more often than CR (p less than 0.01), providing new diagnostic information in 15 patients (46.9 percent), and clarifying CR abnormal...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.91.1.80

    authors: Haponik EF,Britt EJ,Smith PL,Bleecker ER

    更新日期:1987-01-01 00:00:00

  • Congenital aneurysm of the left sinus of Valsalva. Report of a patient with 19-year survival without surgery.

    abstract::An unruptured aneurysm of the left sinus of Valsalva was diagnosed by angiography in a 16-year-old male subject 19 years ago. A recent repeated angiographic study documented no change in the aneurysm over the 19-year interval, and the patient has remained asymptomatic. We are aware of no other long-term follow-up repo...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.90.1.143

    authors: Martin LW,Hsu I,Schwartz H,Wasserman AG

    更新日期:1986-07-01 00:00:00

  • Changes in BP induced by passive leg raising predict response to fluid loading in critically ill patients.

    abstract:OBJECTIVE:To test the hypothesis that passive leg raising (PLR) induces changes in arterial pulse pressure that can help to predict the response to rapid fluid loading (RFL) in patients with acute circulatory failure who are receiving mechanical ventilation. DESIGN:Prospective clinical study. SETTING:Two medical ICUs...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.121.4.1245

    authors: Boulain T,Achard JM,Teboul JL,Richard C,Perrotin D,Ginies G

    更新日期:2002-04-01 00:00:00

  • Increased risk of myocardial infarction and stroke following exacerbation of COPD.

    abstract:OBJECTIVE:Patients with COPD are at risk for cardiovascular events. This is attributed to increased systemic inflammation. The course of COPD is punctuated by exacerbations, which further increase systemic inflammation, but the risk of vascular events in the postexacerbation period has never been defined. METHODS:We a...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-2029

    authors: Donaldson GC,Hurst JR,Smith CJ,Hubbard RB,Wedzicha JA

    更新日期:2010-05-01 00:00:00

  • Clinical Approach to the Therapy of Asthma-COPD Overlap.

    abstract::Over the last few years, there has been a renewed interest in patients with characteristics of both asthma and COPD. Although the precise definition of asthma-COPD overlap (ACO) is still controversial, patients with overlapping features are frequently encountered in clinical practice, and may indeed have worse clinica...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2018.07.028

    authors: Maselli DJ,Hardin M,Christenson SA,Hanania NA,Hersh CP,Adams SG,Anzueto A,Peters JI,Han MK,Martinez FJ

    更新日期:2019-01-01 00:00:00

  • Genetics of asthma and COPD. Similar results for different phenotypes.

    abstract::Asthma and COPD are common respiratory diseases that are caused by the interaction of genetic susceptibility with environmental factors. Environmental influences are important in both diseases, and although there are differences in genetic susceptibilities, there are also similarities. Three examples of interest for b...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.126.2_suppl_1.105S

    authors: Meyers DA,Larj MJ,Lange L

    更新日期:2004-08-01 00:00:00

  • Transition from epoprostenol and treprostinil to the oral endothelin receptor antagonist bosentan in patients with pulmonary hypertension.

    abstract:STUDY OBJECTIVES:Prior to the availability of the oral endothelin antagonist bosentan, most patients with pulmonary arterial hypertension (PAH) were treated with continuously infused prostacyclins. Many patients receiving prostacyclins would have received bosentan if it had been available at the time of their diagnosis...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.126.3.808

    authors: Suleman N,Frost AE

    更新日期:2004-09-01 00:00:00

  • Pulmonary sequestration in the neonate.

    abstract::Pulmonary sequestration is a congenital anomaly resulting in nonfunctioning lung tissue in either the "extralobar" or "intralobar" position. Both forms derive their blood supply from the systemic circulation. Large pulmonary sequestrations can present in the newborn with potentially fatal respiratory distress. Surgica...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.1.244

    authors: Piccione W Jr,Burt ME

    更新日期:1990-01-01 00:00:00

  • Prolonged myocardial ischemia after intravenous dipyridamole thallium imaging.

    abstract::Intravenous dipyridamole thallium imaging is reported to be a safe test with minimal side effects. It has been proposed by some that the test simply dilates the coronary vessels without actually producing myocardial ischemia. In this report, we describe a patient who, following intravenous dipyridamole thallium imagin...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.6.1102

    authors: Lewen MK,Labovitz AJ,Kern MJ,Chaitman BR

    更新日期:1987-12-01 00:00:00

  • Pulmonary edema due to upper airway obstruction in adults.

    abstract::A report of pulmonary edema following acute upper airway obstruction in an adult is presented, and the literature involving 25 additional cases is reviewed. This form of pulmonary edema appears to be related to markedly negative intrathoracic pressure due to forced inspiration against a closed upper airway resulting i...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.94.5.1090

    authors: Willms D,Shure D

    更新日期:1988-11-01 00:00:00

  • Left atrial bacterial mural endocarditis.

    abstract::An unusual case of Staphylococcus aureus endocarditis confined to the mural left atrium is presented. Echocardiographic studies revealed a 1.5 x 2.0-cm vegetation mimicking a myxoma situated in the path of a mitral regurgitant jet on a color Doppler test. Emboli to upper and lower extremities and brain complicated the...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.99.3.757

    authors: Bierbrier GS,Novick RJ,Guiraudon C,Wisenberg G,Boughner D

    更新日期:1991-03-01 00:00:00

  • Intravenous and oral corticosteroids for the prevention of relapse after treatment of decompensated COPD. Effect on patients with a history of multiple relapses.

    abstract::To determine if a regimen of intravenous and oral corticosteroids reduces the relapse rate after treatment of decompensated COPD in the ED, 30 patients were studied. Forty-five visits in which intravenous and oral corticosteroids were given (T visits) were compared with an equal number of matched visits in which they ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.4.845

    authors: Murata GH,Gorby MS,Chick TW,Halperin AK

    更新日期:1990-10-01 00:00:00

  • Hypoxic pulmonary vasoconstriction and gas exchange during exercise in chronic obstructive pulmonary disease.

    abstract::In patients with chronic obstructive pulmonary disease (COPD) studied at rest, nifedipine releases hypoxic pulmonary vasoconstriction (HPV) and worsens gas exchange. During exercise, this drug lowers pulmonary hypertension, but the effects of this lower pulmonary vascular tone on ventilation-perfusion (VA/Q) relations...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.2.268

    authors: Agustí AG,Barberá JA,Roca J,Wagner PD,Guitart R,Rodriguez-Roisín R

    更新日期:1990-02-01 00:00:00

  • Endovascular therapy for left main compression syndrome. Case report and literature review.

    abstract::Extrinsic compression of the left main coronary artery (LMCA) can occur in patients with severe pulmonary hypertension and enlarged pulmonary artery trunk. It has been usually described in the setting of congenital defects such as atrial septal defect, ventricular septal defect, and, more rarely, isolated persistent d...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.08-2922

    authors: Caldera AE,Cruz-Gonzalez I,Bezerra HG,Cury RC,Palacios IF,Cockrill BA,Inglessis-Azuaje I

    更新日期:2009-06-01 00:00:00

  • Vasodilators and primary pulmonary hypertension. Variability of long-term response.

    abstract::Long-term response to vasodilator therapy was assessed in six patients with PPH. Following an acute trial, each patient was restudied after (1) two months of drug administration, (2) one month of abstinence from therapy, and (3) an additional two months of therapy. Three of six patients had no long-term reduction of P...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.6.1185

    authors: Dantzker DR,D'Alonzo GE,Gianotti L,Fuentes F,Nickeson D,Emerson M

    更新日期:1989-06-01 00:00:00