Immune-stimulating properties of polysaccharides from Phellodendri cortex (Hwangbek).

abstract：:Comparing the properties of 'young' and senescent ('aged') O+ erythrocytes isolated by applying ultracentrifugation in a self-forming Percoll gradient, we demonstrate that the sialic acids of membrane glycoconjugates control the life span of erythrocytes and that the desialylation of glycans is responsible for the cle...

journal_title：Glycoconjugate journal

authors： Bratosin D,Mazurier J,Debray H,Lecocq M,Boilly B,Alonso C,Moisei M,Motas C,Montreuil J

更新日期：1995-06-01 00:00:00

abstract：:Syndecan-4 is a transmembrane heparan sulfate proteoglycan belonging to the syndecan family. Syndecan-4-deficient [(Synd4(-/-)] mice were produced to clarify the in vivo role of syndecan-4. Synd4(-/-) mice were more susceptible to kappa-carrageenan-induced nephropathy, and the placental labyrinth from the deficient em...

journal_title：Glycoconjugate journal

authors： Ishiguro K,Kojima T,Muramatsu T

更新日期：2002-05-01 00:00:00

abstract：:The conformational space of methyl 6-O-[(R)- and (S)-1-carboxyethyl]-alpha-D-galactopyranoside has been investigated. A grid search employing energy minimization at each grid point over the three major degrees of freedom, namely phi, psi and omega, identified low energy regions. The R-isomer shows five low energy conf...

journal_title：Glycoconjugate journal

authors： Stenutz R,Widmalm G

更新日期：1997-12-01 00:00:00

abstract：:Fucosylated oligosaccharides have an important role in maintaining a healthy immune system and homeostatic gut microflora. This study employed a commercial β-galactosidase in the production of fucose-containing galacto-oligosaccharides (fGOS) from lactose and fucose. The production was optimized using experiment desig...

journal_title：Glycoconjugate journal

authors： Usvalampi A,Maaheimo H,Tossavainen O,Frey AD

更新日期：2018-02-01 00:00:00

abstract：:Since the alpha-D-galactose-(1-->3)-D-galactose epitope has been identified to be the major target in the process of hyperacute rejection of xenografts transplanted from nonprimate donors to humans, specific inhibitors of alpha-galactosyltransferases are of broad interest. Using Trypanosoma brucei, a protozoan parasit...

journal_title：Glycoconjugate journal

authors： Kolb V,Amann F,Schmidt RR,Duszenko M

更新日期：1999-09-01 00:00:00

abstract：:Eggs from Amphibia are surrounded by several layers of jelly that are needed for proper fertilization. Jelly coat is composed of highly glycosylated mucin-type glycoproteins containing up to 60% of carbohydrates, which display a remarkable species-specificity. This material obtained from Triturus alpestris was submitt...

journal_title：Glycoconjugate journal

authors： Florea D,Maes E,Guérardel Y,Page A,Zanetta JP,Cogalniceanu D,Strecker G

更新日期：2006-07-01 00:00:00

abstract：:We have examined structure-function relationships that have been proposed to account for the heparin-binding properties of basic fibroblast growth factor and its receptor, FGFR-1, using synthetic peptides, DNA synthesis assays and binding assays in a resonant mirror biosensor. The results suggest that the interaction ...

journal_title：Glycoconjugate journal

authors： Kinsella L,Chen HL,Smith JA,Rudland PS,Fernig DG

更新日期：1998-04-01 00:00:00

abstract：:The sap-sucking homopteran insects, commonly known as aphids and leafhoppers are responsible for a huge amount of lost productivity of mustard, chickpea, cabbage, rice and many other important crops. Due to their unique feeding habits and ability to build up a huge population in a very short time, they are very diffic...

journal_title：Glycoconjugate journal

authors： Majumder P,Banerjee S,Das S

更新日期：2004-01-01 00:00:00

abstract：:Podocalyxin (PC) was first identified as a heavily sialylated transmembrane protein of glomerular podocytes. Recent studies suggest that PC is a remarkable glycoconjugate that acts as a universal glyco-carrier. The glycoforms of PC are responsible for multiple functions in normal tissue, human cancer cells, human embr...

journal_title：Glycoconjugate journal

authors： Toyoda H,Nagai Y,Kojima A,Kinoshita-Toyoda A

更新日期：2017-04-01 00:00:00

abstract：:Altered glycosylation of plasma proteins has been directly implicated in the pathogenesis of rheumatoid arthritis (RA). The present study investigated the changes in the Concanavalin-A (Con-A)-bound plasma proteins in the RA patients in comparison to that of the healthy controls. Two proteins (MW approximately 32 kDa ...

journal_title：Glycoconjugate journal

authors： Raghav SK,Gupta B,Agrawal C,Saroha A,Das RH,Chaturvedi VP,Das HR

更新日期：2006-05-01 00:00:00

abstract：:The SewA385T mutation of the FUT2 gene was found to correlate with both the erthrocyte Le(a + b+) and/or salivary ABH partial-secretor phenotypes of Polynesians. Constructs with FUT1 and FUT2 wild type genes, and the FUT2 SewA385T, seG428A and seC571T mutated alleles, were cloned into pcDNAI, and expressed in COS-7 ce...

journal_title：Glycoconjugate journal

authors： Henry S,Mollicone R,Fernandez P,Samuelsson B,Oriol R,Larson G

更新日期：1996-12-01 00:00:00

abstract：:Serum GP73 is a functional resident Golgi type II membrane protein with three potential N-glycosylation sites. In this study, we used multiple lectin assays to analyze glycan patterns of serum GP73 and evaluated its diagnostic value for distinguishing hepatocellular carcinoma (HCC) from liver cirrhosis (LC). Firstly, ...

journal_title：Glycoconjugate journal

authors： Jiang K,Shang S,Li W,Guo K,Qin X,Zhang S,Liu Y

更新日期：2015-12-01 00:00:00

abstract：:Coarse tea is made of mature tea plant (Camellia sinensis L.) shoots and is generally discarded as a worthless crop product, but has been proved an excellent material for the treatment of diabetes. This study aims to evaluate the effects of the extraction techniques WE (water extraction), UAE (ultrasound-assisted extr...

journal_title：Glycoconjugate journal

authors： Zhu J,Chen Z,Zhou H,Yu C,Han Z,Shao S,Hu X,Wei X,Wang Y

更新日期：2020-04-01 00:00:00

abstract：:Mannose 6-phosphate receptor proteins (MPR 300 and 46) are type 1 transmembrane glycoproteins that mediate transport of lysosomal enzymes to lysosomes. In a recent study we have purified both receptors from goat liver and raised antibodies. An ELISA method was developed that allowed quantification of both receptors in...

journal_title：Glycoconjugate journal

authors： Suresh K,Vegiraju SR,Nadimpalli SK

更新日期：2004-01-01 00:00:00

abstract：:This review discusses the challenges facing research in 'functional glycomics' and the novel technologies that are being developed to advance the field. The structural complexity of glycans and glycoconjugates makes studies of both their structures and recognition difficult. However, these intricate structures can be ...

journal_title：Glycoconjugate journal

authors： Song X,Heimburg-Molinaro J,Smith DF,Cummings RD

更新日期：2015-10-01 00:00:00

abstract：:Multidisciplinary approaches by a number of investigators have established that cell-surface carbohydrates are integral components of recognition systems regulating survival, migration, adhesion, growth and differentiation of various cells. Our own experience and contributions to this exciting field are described. We ...

journal_title：Glycoconjugate journal

authors： Muramatsu T

更新日期：2000-07-01 00:00:00

abstract：:Two rhamnobiose-lipid preparations have been studied by fast atom bombardment (FAB) tandem mass spectrometry. The principal rhamnobiose-lipids contain the beta-hydroxydecanoyl-beta-hydroxydecanoate Rha-Rha-C10-C10 and the beta-hydroxytetradecanoyl-beta-hydroxytetradecanoate Rha-Rha-C14-C14. Both preparations contain m...

journal_title：Glycoconjugate journal

authors： Manso Pajarron A,De Koster CG,Heerma W,Schmidt M,Haverkamp J

更新日期：1993-06-01 00:00:00

abstract：:Cultured chondrocytes derived from the caudal and cephalic ends of embryonic chick sterna have been compared with each other and with whole sternum, by using a panel of 21 lectins to probe the distribution of oligosaccharides in glycoconjugates of cells and matrix at various times of culture or development. On culture...

journal_title：Glycoconjugate journal

authors： McClure SF,Stoddart RW,McClure J

更新日期：1997-04-01 00:00:00

abstract：:The metabolism of glycosphingolipids is strictly regulated during the mitotic cell cycle. Before the G1-to-S transition, the ceramide and glucosylceramide concentration is elevated. Ceramide induces apoptosis synergistically with the pro-apoptotic protein prostate apoptosis response 4 (PAR-4) that may be asymmetricall...

journal_title：Glycoconjugate journal

authors： Bieberich E

更新日期：2004-01-01 00:00:00

abstract：:We analyzed surface glycoproteins of human natural killer (NK) cells by utilizing lectins. Among the lectins tested, wheat germ agglutinin (WGA) was found to bind preferentially to CD16(Leu11)-positive lymphocytes as determined by two-colour flow cytometry. Analysis of glycoproteins in the lysate prepared from NK cell...

journal_title：Glycoconjugate journal

authors： Harada K,Yamane H,Imai Y,Tsuji T,Toyoshima S,Osawa T

更新日期：1992-08-01 00:00:00

abstract：:Full proton NMR assignments have been achieved for the alpha(1-3)-linked fucose residues contained in alkaline borohydride reduced keratan sulphate chains derived from bovine articular cartilage. This involved 500 MHz spectroscopy at 60 degrees C and included COSY and RELAYED-COSY determinations. ...

journal_title：Glycoconjugate journal

authors： Huckerby TN,Nieduszynski IA,Brown GM,Cockin GH

更新日期：1991-02-01 00:00:00

abstract：:Filamentous fungi are commonly used in the fermentation industry for large scale production of glycoproteins. Several of these proteins can be produced in concentrations up to 20-40 g per litre. The production of heterologous glycoproteins is at least one or two orders of magnitude lower but research is in progress to...

journal_title：Glycoconjugate journal

authors： Maras M,van Die I,Contreras R,van den Hondel CA

更新日期：1999-02-01 00:00:00

abstract：:The small keratan sulphate proteoglycan, fibromodulin, has been isolated from pooled human articular cartilage. The main chain repeat region and the chain caps from the attached N-linked keratan sulphate chains have been fragmented by keratanase II digestion, and the oligosaccharides generated have been reduced and is...

journal_title：Glycoconjugate journal

authors： Lauder RM,Huckerby TN,Nieduszynski IA

更新日期：1997-08-01 00:00:00

abstract：:Using printed glycan array (PGA) we compared the results of antibody profiling in undiluted, moderately (1:15) and highly (1:100) diluted human blood serum. Undiluted serum is suitable for studying blood as a tissue in its native state, whereas to study the serum of newborns or small animals one usually has to dilute ...

journal_title：Glycoconjugate journal

authors： Shilova N,Navakouski M,Khasbiullina N,Blixt O,Bovin N

更新日期：2012-04-01 00:00:00

abstract：:Our recent studies have revealed the existence of two distinct Gal: 3-O-sulfotransferases capable of acting on the C-3 position of galactose in a Core 2 branched structure, e.g., Galbeta1-->4GlcNAcbeta1-->6(Galbeta1-->3)GalNacalph a1-->OBenzyl as acceptor to give 3-O-sulfoGalbeta1-->4GlcNAcbeta1-->3(Galbeta1-->3)G alN...

journal_title：Glycoconjugate journal

authors： Jain RK,Piskorz CF,Chandrasekaran EV,Matta KL

更新日期：1998-10-01 00:00:00

abstract：:We have used two methods to evaluate the level of expression of Gb3Cer in several human leukaemia/lymphoma cell lines representative of the myeloid (K562, KG-1, HL-60, and lymphoid (Reh, Daudi, Raji, RPMI 8226, CCRF-CEM, MOLT-4) lineages blocked at varied stages of differentiation. TLC immunostaining of glycolipid ext...

journal_title：Glycoconjugate journal

authors： Stults CL,Larsen RD,Macher BA

更新日期：1995-10-01 00:00:00

abstract：:A major impediment in the analysis of glycosaminoglycans is the difficulty to cleave quantitatively the glycosidic bonds because of the stabilisation of glycosidic bonds and of the relative instability of the liberated constituents. This manuscript describes a modified procedure of methanolysis in the presence of bari...

journal_title：Glycoconjugate journal

authors： Zanetta JP,Timmerman P,Leroy Y

更新日期：1999-10-01 00:00:00

abstract：:Type 1 ABO blood group antigens (peripheral core structure: Gal beta 1-3GlcNAc beta 1-R) are expressed mainly in endodermally-derived tissues, but are not synthesized in mesodermally-derived tissues. In the former tissues, H type 1 antigen is generated largely by alpha-2-L-fucosyltransferase encoded by secretor (Se) g...

journal_title：Glycoconjugate journal

authors： Tanegashima A,Nishi K,Fukunaga T,Rand S,Brinkmann B

更新日期：1996-08-01 00:00:00

abstract：:Duffy antigen/receptor for chemokines (DARC) is a glycosylated seven-transmembrane protein acting as a blood group antigen, a chemokine binding protein and a receptor for Plasmodium vivax malaria parasite. It is present on erythrocytes and endothelial cells of postcapillary venules. The N-terminal extracellular domain...

journal_title：Glycoconjugate journal

authors： Grodecka M,Bertrand O,Karolak E,Lisowski M,Waśniowska K

更新日期：2012-04-01 00:00:00

abstract：:The expression of neutral glycosphingolipids and gangliosides has been studied in human skeletal and heart muscle using indirect immunofluorescence microscopy. Transversal and longitudinal cryosections were immunostained with specific monoclonal and polyclonal antibodies against the neural glycosphingolipids lactosylc...

journal_title：Glycoconjugate journal

authors： Cacić M,Müthing J,Kracun I,Neumann U,Weber-Schürholz S

更新日期：1994-10-01 00:00:00