Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.

abstract：BACKGROUND:Essential hypertension ranks among the strongest cardiovascular risk factors. Cytokine production by monocytes plays a key role in atherosclerosis development and acute coronary syndromes. We investigated whether stimulated monocyte cytokine release and its inhibition by glucocorticoids would differ between ...

journal_title：American journal of hypertension

authors： Wirtz PH,von Känel R,Frey K,Ehlert U,Fischer JE

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Inadequately treated hypertension (HTN) leads to considerable morbidity and mortality. Despite many treatment options, blood pressure (BP) control is suboptimal. Missed opportunities due to the growing complexity of primary care office visits contribute. Electronic health records (EHRs) offer best practice a...

journal_title：American journal of hypertension

authors： Swedlund M,Norton D,Birstler J,Chen G,Cruz L,Hanrahan L

更新日期：2019-01-01 00:00:00

abstract：:This multicenter, randomized, controlled clinical trial assessed the influence of sodium chloride intake on the antihypertensive effect of the calcium channel blocker isradipine. Participants with uncomplicated hypertension controlled by isradipine entered a 4-week sodium-restricted (60 to 80 mmol/24 h) period. Partic...

journal_title：American journal of hypertension

authors： McCarron DA,Weder AB,Egan BM,Krishna GG,Morris CD,Cohen M,Oparil S

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:This study examines the interrelationship between gestational weight gain, pre-pregnancy body mass index (BMI), race/ethnicity, and their association with hypertensive disorders during pregnancy (HDP). METHODS:Data from the 2004-2011 national Pregnancy Risk Assessment Monitoring System (PRAMS) were analyzed...

journal_title：American journal of hypertension

authors： Masho SW,Urban P,Cha S,Ramus R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:In chronic kidney disease, intensive systolic blood pressure (SBP) control reduces mortality at a cost of greater acute kidney injury risk. Kidney transplantation involves implantation of denervated kidneys and immunosuppressive medications that increase acute kidney injury risk. The optimal blood pressure (...

journal_title：American journal of hypertension

authors： Malhotra R,Katz R,Weiner DE,Levey AS,Cheung AK,Bostom AG,Ix JH

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:Elastin microfibril interfacer 1 (EMILIN-1) is a negative regulator of the transforming growth factor-beta (TGF-beta) signaling, which is involved in blood pressure (BP) homeostasis. Emilin1 knockout mice display elevated BP. The aim of the present study was to assess the association between the human EMILIN...

journal_title：American journal of hypertension

authors： Shimodaira M,Nakayama T,Sato N,Naganuma T,Yamaguchi M,Aoi N,Sato M,Izumi Y,Soma M,Matsumoto K

更新日期：2010-05-01 00:00:00

abstract：:The levels and molecular form of atrial natriuretic peptide-like immunoreactivity (ANP-LI) in human atrial tissue were investigated. The levels of right atrial ANP-LI were significantly higher in mitral disease than in other cardiac or noncardiac diseases. The increased ANP-LI was mainly accounted for by an increase i...

journal_title：American journal of hypertension

authors： Naruse M,Hiroe M,Naruse K,Nagata M,Ohno H,Hashimoto A,Koyanagi H,Sekiguchi M,Demura H,Hirosawa K

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases. ...

journal_title：American journal of hypertension

authors： Bundy JD,Jaeger BC,Huffman MD,Knox SS,Thomas SJ,Shimbo D,Booth Iii JN,Lewis CE,Edwards LJ,Schwartz JE,Muntner P

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:In patients free from overt cardiac disease, R wave in aVL lead (RaVL) is strongly correlated with left ventricular mass index (LVMI) assessed by transthoracic echocardiography. The aim of the present study was to extend this finding to other settings (cardiomyopathy or conduction disorders), by comparing EC...

journal_title：American journal of hypertension

authors： Courand PY,Grandjean A,Charles P,Paget V,Khettab F,Bricca G,Boussel L,Lantelme P,Harbaoui B

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) induces inflammation and vascular damage that might contribute to an increased risk of cardiovascular disease (CVD). However, the mechanisms linking OSA and CVD are not fully understood. Pentraxin3 may play a significant role in vascular inflammation and damage. Currently, there...

journal_title：American journal of hypertension

authors： Kasai T,Inoue K,Kumagai T,Kato M,Kawana F,Sagara M,Ishiwata S,Ohno M,Yamaguchi T,Momomura S,Narui K

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:The renal resistive index (RI) measured using Doppler ultrasonography has been used as a diagnostic tool in the daily work-up of kidney diseases. A better understanding of its relationship with preclinical organ damage may help in determining overall cardiovascular risk in hypertensive patients. METHODS:We ...

journal_title：American journal of hypertension

authors： Doi Y,Iwashima Y,Yoshihara F,Kamide K,Takata H,Fujii T,Kubota Y,Nakamura S,Horio T,Kawano Y

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Morning blood pressure (BP) surge seems to be a risk factor for cardiovascular events. Although physical activity after arising significantly affects morning BP surge, it has remained unclear whether morning BP surge after controlling for physical activity (morning BP reactivity) is associated with target or...

journal_title：American journal of hypertension

authors： Kaneda R,Kario K,Hoshide S,Umeda Y,Hoshide Y,Shimada K

更新日期：2005-12-01 00:00:00

abstract：:Angiotensin II (Ang II) plays important roles in the development of cardiovascular diseases including hypertension, renal diseases, cardiac hypertrophy, congestive heart failure, and ischemic heart disease. Angiotensin II exerts classic hemodynamic and renal effects, but it is also a local biologically active mediator...

journal_title：American journal of hypertension

authors： Levy BI

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Experimentally induced sleep deprivation can raise blood pressure (BP) and worsen hypertension. We recently reported a significantly higher prevalence of obstructive sleep apnea (OSA) and reduced rapid eye movement (REM) sleep time in drug-resistant hypertensives compared to controlled hypertensives. The obj...

journal_title：American journal of hypertension

authors： Friedman O,Bradley TD,Ruttanaumpawan P,Logan AG

更新日期：2010-02-01 00:00:00

abstract：:Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide and regulator of blood flow that plays an important role in blood pressure (BP) elevation in some models of experimental hypertension such as DOCA-salt rat, DOCA-salt-treated spontaneously hypertensive rats (SHR), stroke-prone SHR, Dahl salt-sensitive rats, ang...

journal_title：American journal of hypertension

authors： Schiffrin EL

更新日期：2001-06-01 00:00:00

abstract：:In many reports, the prevalence of target organ damage in renovascular hypertension (RVH) appears to be higher than in essential hypertension (EH). Since in most studies the renal artery stenosis is part of a diffuse atherosclerotic disease, it is not known whether these complications are due to RVH itself or to the v...

journal_title：American journal of hypertension

authors： Losito A,Fagugli RM,Zampi I,Parente B,de Rango P,Giordano G,Cao P

更新日期：1996-11-01 00:00:00

abstract：:The aim of this study was to evaluate the delayed effects of an angiotensin converting enzyme (ACE) inhibitor on blood pressure and on structural and functional alterations in mesenteric small resistance arteries of spontaneously hypertensive rats (SHR). The ACE inhibitor fosinopril (25 mg/kg/day) was administered acc...

journal_title：American journal of hypertension

authors： Rizzoni D,Castellano M,Porteri E,Bettoni G,Muiesan ML,Cinelli A,Zulli R,Rosei EA

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Sleep apnea is being studied as a risk factor for hypertension. This observational chart review was conducted to determine the long-term effects of continuous positive airway pressure (CPAP) treatment on blood pressure (BP) in a sample of sleep apnea patients from urban and rural populations. METHODS:This s...

journal_title：American journal of hypertension

authors： Dhillon S,Chung SA,Fargher T,Huterer N,Shapiro CM

更新日期：2005-05-01 00:00:00

abstract：:An intravenous glucose tolerance test (IVGTT) was performed on 16 spontaneously hypertensive rats (SHR) and 15 Wistar-Kyoto rats (WKY) by challenging them with an intravenous glucose load of 0.125 g/100 g body weight. Serum glucose and insulin were measured at 0, 15, 30, 60, 120, and 240 min. In a second experiment, o...

journal_title：American journal of hypertension

authors： Gaboury CL,Karanja N,Holcomb SR,Torok J,McCarron DA

更新日期：1991-08-01 00:00:00

abstract：:The syndrome of apparent mineralocorticoid excess (AME) is characterized by persistent hypertension and hypokalemia, which is caused by impaired inactivation of cortisol (F) to cortisone (E). The thyroid hormone has been known to influence the F to E conversion leading to efficacious inactivation of F into E. However,...

journal_title：American journal of hypertension

authors： Inagaki K,Otsuka F,Otani H,Sato C,Miyoshi T,Ogura T,Makino H

更新日期：2007-01-01 00:00:00

abstract：:Insulin resistance and hypertension, as well as dyslipidemia, frequently cooccur. Evidence that nitric oxide (NO) plays a crucial role in the long-term regulation of systolic blood pressure led us to examine whether enhanced vasoconstriction and hypertension induced by NO synthase inhibitor could lead to insulin and l...

journal_title：American journal of hypertension

authors： Erlich Y,Rosenthal T

更新日期：1998-09-01 00:00:00

abstract：:Using a new ion selective electrode (ISE) to measure ionized magnesium (IMg2+), we compared levels of IMg2+ with total magnesium (TMg) and serum ionized calcium levels (ICa2+) in umbilical arterial and venous serum of 13 parturients who developed transient hypertension in labor with levels in 38 who remained normotens...

journal_title：American journal of hypertension

authors： Handwerker SM,Altura BT,Royo B,Altura BM

更新日期：1993-06-01 00:00:00

abstract：:Apart from the well-known role of hypertension in cerebrovascular disease, visit-to-visit blood pressure (BP) variability is emerging as an independent risk factor for stroke. Although the underlying mechanism is not fully understood, artery remodeling is thought to be closely involved in the relationship between visi...

journal_title：American journal of hypertension

authors： Nagai M,Kario K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status. METHODS:Two thousand five hundred and three individuals born in 1921-1954 at the Peking Union Medical College Hospital (PUMCH) were targeted; 2,081 (83.1...

journal_title：American journal of hypertension

authors： Chen X,Zhang ZX,George LK,Wang ZS,Fan ZJ,Xu T,Zhou XL,Han SM,Wen HB,Zeng Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The X-linked angiotensin II type-2 receptor (AT2R) gene 1675G/A polymorphism is located in the short intron 1 of the AT2R gene within a sequence motif conforming to a splice branch site. AT2R is expressed in the human retina, but no previous study examined the association between retinal microvascular phenot...

journal_title：American journal of hypertension

authors： Liu YP,Kuznetsova T,Thijs L,Jin Y,Schmitz B,Brand SM,Brand E,Manunta P,Bianchi G,Struijker-Boudier H,Staessen JA

更新日期：2011-12-01 00:00:00

abstract：:Longitudinal studies in children have tracked blood pressure through childhood and from childhood into adult life. However, many children do not maintain their rank during these periods of observation. Several of the factors contributing to maintenance of rank order are reviewed, such as initial level of blood pressur...

journal_title：American journal of hypertension

authors： Mahoney LT,Clarke WR,Burns TL,Lauer RM

更新日期：1991-11-01 00:00:00

abstract：:To study the circulating humoral factor modifying transmembrane sodium transport, plasma was obtained from 12 patients with essential hypertension (EH) fed a high sodium diet (NaCl 15 to 17 g/d) for seven days and thereafter a low sodium diet (NaCl 2 to 3 g/d) for seven days. Ouabain-sensitive 86Rb+ influx into the re...

journal_title：American journal of hypertension

authors： Ashida T,Kuramochi M,Kojima S,Yoshimi H,Kawano Y,Kimura G,Abe H,Imanishi M,Yoshida K,Kawamura M

更新日期：1989-07-01 00:00:00

abstract：:Thromboembolic complications such as ischemic stroke and myocardial infarction are significantly more frequent in patients with arterial hypertension. From the available intervention studies, it appears that pharmacologic treatment of hypertension-at least with diuretics and beta-blockers-may more effectively protect ...

journal_title：American journal of hypertension

authors： Lottermoser K,Weisser B,Hertfelder HJ,Wöstmann B,Vetter H,Düsing R

更新日期：1998-03-01 00:00:00

abstract：:Among the major mechanisms controlling the renal release of renin, renal nerves are known to exert a direct stimulating action on juxtaglomerular cells that is mediated by beta-adrenoceptors. Activation of the renal nerves also exerts an important permissive role in order to amplify and possibly accelerate responses t...

journal_title：American journal of hypertension

authors： Stella A,Golin R,Zanchetti A

更新日期：1989-02-01 00:00:00

abstract：:Vasodilation is impaired in various conditions, such as hypercholesterolemia and tobacco use. We evaluated brachial artery flow-mediated vasodilation (FMD) after blood pressure (BP) cuff occlusion using high-resolution B-mode ultrasound in 20 alcoholics, without any coexisting conditions such as smoking, hypertension,...

journal_title：American journal of hypertension

authors： Maiorano G,Bartolomucci F,Contursi V,Minenna FS,Di Mise R,Palasciano A,Allegrini B,Amoruso M,Kozàkovà M

更新日期：1999-02-01 00:00:00