The "P's and Q's" of quality systems.

abstract：OBJECTIVE:Bcl-2 and p53 genes may participate in a common pathway for regulation of apoptosis. The aims of this study were (1) to study the immunohistochemical expression of the bcl-2 oncoprotein in colorectal tumors, (2) to correlate it with that of p53 protein overexpression, and (3) to compare it with histopathologi...

journal_title：Archives of pathology & laboratory medicine

authors： Mosnier JF,Perret AG,Vindimian M,Dumollard JM,Balique JG,Perpoint B,Boucheron S

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:To assess the clinical utility of an enzyme-linked immunosorbent assay method for the quantitative detection of Candida species antigen (Candigen; Biomerica Inc, Newport Beach, Calif) in patients with suspected disseminated candidiasis. METHODS:Specimens of blood or cerebrospinal fluid from 75 patients with ...

journal_title：Archives of pathology & laboratory medicine

authors： Elsayed S,Fitzgerald V,Massey V,Hussain Z

更新日期：2001-03-01 00:00:00

abstract：:Primary leiomyosarcoma of the pancreas is a rare tumor for which only 21 reports appear in the world literature. We describe an additional case of pancreatic leiomyosarcoma in a 76-year-old man, who complained of persistent high fever. Histologic examination revealed a pleomorphic spindle cell tumor. Reactivity for mu...

journal_title：Archives of pathology & laboratory medicine

authors： Nesi G,Pantalone D,Ragionieri I,Amorosi A

更新日期：2001-01-01 00:00:00

abstract：:Laboratories contemplating either the addition of new molecular tests or modifying methods approved by the Food and Drug Administration for human papillomavirus testing should be aware of a variety of procedural, performance, and regulatory issues surrounding such activity. Diagnostic medical laboratory testing in the...

journal_title：Archives of pathology & laboratory medicine

authors： Seabrook JM,Hubbard RA

更新日期：2003-08-01 00:00:00

abstract：CONTEXT:-Evaluation of 12 or more lymph nodes (LNs) is currently used as a quality indicator for adequacy of pathologic examination of colon cancer resections. OBJECTIVE:-To evaluate the utility of a focused LN search in the immediate vicinity of the tumor and a "second look" protocol in improving LN staging in colon ...

journal_title：Archives of pathology & laboratory medicine

authors： Lisovsky M,Schutz SN,Drage MG,Liu X,Suriawinata AA,Srivastava A

更新日期：2017-01-01 00:00:00

abstract：CONTEXT:Burkitt lymphoma (BL) is endemic in Uganda and because of the high incidence, diagnosis is often presumed during clinical care and epidemiologic studies. OBJECTIVES:To assess the accuracy of the clinical and the local pathology diagnosis of BL as assessed by an outside pathology review diagnosis and to underst...

journal_title：Archives of pathology & laboratory medicine

authors： Ogwang MD,Zhao W,Ayers LW,Mbulaiteye SM

更新日期：2011-04-01 00:00:00

abstract：:Revolutionary advances in technology have enhanced our understanding of the genetic changes that occur in cancer cells. This article summarizes some of the basic features of these techniques and describes their application to the identification of specific types of genetic alterations in cells. The emphasis is on thei...

journal_title：Archives of pathology & laboratory medicine

authors： Rowley JD,Aster JC,Sklar J

更新日期：1993-11-01 00:00:00

abstract：:Hyalinized glomeruli in tissue sections those isolated from kidneys of subjected with end-stage and diabetic nephropathies and from aged persons (older than 75 years) were studied by histochemical, immunohistochemical, electron microscopic, and chemical methods. Our purposes were as follows: (1) to clarify the pathoge...

journal_title：Archives of pathology & laboratory medicine

authors： Misra RP

更新日期：1981-11-01 00:00:00

abstract：:Precision medicine is altering the traditional role of the surgical pathologist in caring for patients with lung cancer. Diagnosing specific cell type is now a foundation for selecting lung cancers for predictive-biomarker testing by molecular techniques. Using conventional techniques and familiar equipment, the surgi...

journal_title：Archives of pathology & laboratory medicine

authors： Cagle PT,Myers J

更新日期：2012-10-01 00:00:00

abstract：:Atherosclerosis can be defined as a disease process that occurs when the influx and deposition of cholesterol into the arterial wall exceed the egress of cholesterol from the arterial wall. This process is characterized by early deposition of cholesterol in and around arterial wall cells. The cholesterol is derived fr...

journal_title：Archives of pathology & laboratory medicine

authors： Mahley RW

更新日期：1983-08-01 00:00:00

abstract：:Recombinant DNA technology has already had a major impact on our understanding of microbiology, cell biology, and genetic diseases and it will certainly have extensive applications in laboratory medicine. The techniques of restriction endonuclease analysis of DNA, nucleic acid hybridization after electrophoretic separ...

journal_title：Archives of pathology & laboratory medicine

authors： Rabson AB,Rabson AS

更新日期：1983-10-01 00:00:00

abstract：:Krukenberg tumor is an uncommon metastatic tumor of the ovary. This article provides an overview of the major pathologic manifestations of Krukenberg tumor, patient characteristics, clinical and laboratory features of the disease, prognostic factors, and current knowledge about its pathogenesis. Pathologists have to b...

journal_title：Archives of pathology & laboratory medicine

authors： Al-Agha OM,Nicastri AD

更新日期：2006-11-01 00:00:00

abstract：:Concerns regarding significant levels of inappropriate medical services--as high as 20% or more--continue to influence discussions regarding medical care quality, utilization, and costs. The basis of these concerns are findings from a series of studies of the appropriateness of use of several medical and surgical serv...

journal_title：Archives of pathology & laboratory medicine

authors： Kelly JT,Kellie SE

更新日期：1990-11-01 00:00:00

abstract：CONTEXT:Dysregulation of mediators of apoptosis is associated with carcinogenesis. For biliary duct cancers, p53 gene mutation is an important contributor to carcinogenesis. Mutations in the p53 gene affect transcription of the Fas gene, resulting in lack of Fas expression on cell membrane. It has been previously shown...

journal_title：Archives of pathology & laboratory medicine

authors： Jhala NC,Vickers SM,Argani P,McDonald JM

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:To identify resources and summarize important issues in anatomic and clinical pathology training and to assist the pathology resident candidate in evaluating potential training programs. DATA SOURCES:Published guides for medical residency applicants, recent literature discussing pathology education, and Wor...

journal_title：Archives of pathology & laboratory medicine

authors： Yorke RF

更新日期：2000-06-01 00:00:00

abstract：:The demands for information retrieval, processing, and synthesis placed on all providers of health care have increased dramatically in the last several decades. Although systems have been developed to capture charge-related data in support of cost reimbursement, there has been a conspicuous lack of attention paid to i...

journal_title：Archives of pathology & laboratory medicine

authors： Korpman RA

更新日期：1987-07-01 00:00:00

abstract：:Quantitative cell counts on specific pituitary areas were done on differentially stained adenohypophyseal sections obtained at autopsy (four to 22 hours postmortem). We used specific criteria formulated from studies by previous authors to identify functional classes of secretory cells. We compared the effects of two f...

journal_title：Archives of pathology & laboratory medicine

authors： Fowler MR,McKeel DW Jr

更新日期：1979-11-01 00:00:00

abstract：:A premature infant had three pseudoaneurysms of the thoracic and abdominal aorta secondary to umbilical artery catheterization and sepsis. The infant had septicemia as the direct result of bacterial contamination of an umbilical artery catheter with Staphylococcus aureus. The thoracic pseudoaneurysm caused massive hem...

journal_title：Archives of pathology & laboratory medicine

authors： Rabin E,Vye MV,Farrell EE

更新日期：1986-05-01 00:00:00

abstract：:A pathogenetic relationship between hepatic manifestations of alpha 1-antitrypsin deficiency (AATD) and hepatocellular carcinoma has previously been suggested but not established. We encountered three patients with hepatocellular carcinoma (HCC) and nonneoplastic hepatocytes containing globules positive for alpha 1-an...

journal_title：Archives of pathology & laboratory medicine

authors： Rubel LR,Ishak KG,Benjamin SB,Knuff TE

更新日期：1982-12-01 00:00:00

abstract：CONTEXT:- Although many mesotheliomas are related to asbestos exposure, not all are, and there is increasing information on other causes of mesothelioma. OBJECTIVE:- To provide a review of non-asbestos causes for malignant mesothelioma. DATA SOURCES:- Review of relevant published literature via PubMed and other searc...

journal_title：Archives of pathology & laboratory medicine

authors： Attanoos RL,Churg A,Galateau-Salle F,Gibbs AR,Roggli VL

更新日期：2018-06-01 00:00:00

abstract：:Coccidioidomycosis has been reported in almost every tissue of the human body. The gastrointestinal tract and breast have been uniquely spared from this fungal infection. Despite the exceedingly large number of screening mammographies that are performed every year, to our knowledge subcutaneous breast tissue involveme...

journal_title：Archives of pathology & laboratory medicine

authors： Bocian JJ,Fahmy RN,Michas CA

更新日期：1991-10-01 00:00:00

abstract：:Just as electronic health records are transforming the practice of medicine and health care information management, practicing in the era of the electronic health record offers opportunities, if not imperatives, for pathologists to take on new and "transformative" professional and leadership roles for the organization...

journal_title：Archives of pathology & laboratory medicine

authors： Henricks WH,Wilkerson ML,Castellani WJ,Whitsitt MS,Sinard JH

更新日期：2015-03-01 00:00:00

abstract：:We report a case of sialadenoma papilliferum arising in the adenoids in a 2-year-old child. The tumor demonstrated papillary and adenomatous proliferations, suggestive of minor salivary gland origin. A review of the literature indicated no reported cases of this neoplasm arising in individuals this young. The location...

journal_title：Archives of pathology & laboratory medicine

authors： Masi JD,Hoang KG,Sawyer R

更新日期：1986-06-01 00:00:00

abstract：:Herein, we report a case of cutaneous angiosarcoma in a 35-year-old, morbidly obese woman. The tumor arose in the most dependent portion of the lower abdominal panniculus and showed typical changes of chronic lymphedema. The patient underwent a radical resection of her lower abdominal wall panniculus, which showed a m...

journal_title：Archives of pathology & laboratory medicine

authors： Azam M,Saboorian H,Bieligk S,Smith T,Molberg K

更新日期：2001-04-01 00:00:00

abstract：:Clear cell sarcoma shares features with melanoma, but frequently shows EWSR1 rearrangements. It is an aggressive tumor typically occurring in the soft tissues of the extremities, with a gastrointestinal variant with less consistent melanocytic differentiation. It is extremely rare in the head and neck region, with no ...

journal_title：Archives of pathology & laboratory medicine

authors： Kraft S,Antonescu CR,Rosenberg AE,Deschler DG,Nielsen GP

更新日期：2013-11-01 00:00:00

abstract：:The sophomore pathology course at the University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, was substantially modified with the intention of promoting guided, independent learning. The emphasis has been shifted from lectures to other modalities of instruction. This article...

journal_title：Archives of pathology & laboratory medicine

authors： Raskova J,Martin EG,Trelstad RL,Shea SM

更新日期：1989-02-01 00:00:00

abstract：CONTEXT:-Multiple sources have identified challenges that training programs face in preparing graduates for the "real world" practice of pathology, and many training programs have sought to decrease the gap between skills acquired during training and those required in practice. However, there exists the possibility tha...

journal_title：Archives of pathology & laboratory medicine

authors： Post MD,Johnson K,Brissette MD,Conran RM,Domen RE,Hoffman RD,McCloskey CB,Raciti PM,Roberts CA,Rojiani AM,Tucker JA,Powell SZ

更新日期：2017-02-01 00:00:00

abstract：:A study was undertaken of 14 autopsy cases with pigmented rib cartilage. Twelve of these patients had been treated with levodopa because of Parkinson's disease for at least 6 years, and two had been treated with methyldopa because of essential hypertension for 19 years. Thirty-two percent of the autopsy cases of Parki...

journal_title：Archives of pathology & laboratory medicine

authors： Rausing A,Rosén U

更新日期：1994-05-01 00:00:00

abstract：CONTEXT:Aperio Technologies, Inc (Vista, California) provides a new immunohistochemistry (IHC) HER2 Image Analysis (IA) system that allows tuning of the intensity thresholds of the HER2/ neu scoring scheme to adapt to the staining characteristics of different reagents. OBJECTIVE:To compare the trainable IHC HER2 IA sy...

journal_title：Archives of pathology & laboratory medicine

authors： Nassar A,Cohen C,Agersborg SS,Zhou W,Lynch KA,Albitar M,Barker EA,Vanderbilt BL,Thompson J,Heyman ER,Lange H,Olson A,Siddiqui MT

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:In immunohistochemistry, nonstandardized antigen retrieval protocols and fluids, poor-quality antibodies, and the presence of endogenous biotin frequently lead to incorrect results. Recently, advanced reagents including bifunctional SkipDewax pretreatment solution (BSPS), rabbit monoclonal (RM) antibodies, and ...

journal_title：Archives of pathology & laboratory medicine

authors： Wong SC,Chan JK,Lo ES,Chan AK,Wong MC,Chan CM,Lam MY,Chan AT

更新日期：2007-07-01 00:00:00