Urinary glycosaminoglycan excretion in urolithiasis.

Abstract:

:Urinary glycosaminoglycan (GAG) excretion was measured in children with idiopathic urolithiasis (15 girls and 10 boys; mean (SD) age 6.2 (2.4) years) and in healthy controls (10 girls and 14 boys; mean (SD) age 6.8 (3.8) years). GAG excretion was expressed as a GAG/creatinine (mg/g) ratio and was evaluated using dimethylmethylene blue. In healthy control children, the mean (SD) GAG/creatinine ratio was 31.67 (12.76) and it was similar in girls and boys. The children with idiopathic urolithiasis had significantly lower mean (SD) GAG/creatinine ratios than controls (22.59 (7.35)). Therefore, urinary GAG excretion may be important in the disease process in children with urolithiasis, as it is in adults.

journal_name

Arch Dis Child

authors

Akçay T,Konukoğlu D,Dínçer Y

doi

10.1136/adc.80.3.271

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

271-2

issue

3

eissn

0003-9888

issn

1468-2044

journal_volume

80

pub_type

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