Abstract:
PURPOSE:The aim of this study was to determine the relationship of HLA typing in patients with otosclerosis. MATERIALS AND METHODS:We used a prospective study in which HLA typing of 100 surgically confirmed otosclerosis patients were compared with age and sex matched normal individuals. RESULTS:HLA-A3, HLA-A9, HLA-A11, and HLA-B13 were found to be significantly higher (P < .05, .01, and .01, respectively). HLA-A9 and HLA-A11 were found to be higher (P < .01) in patients with a positive family history, indicating genetic heterogenicity. CONCLUSIONS:Higher values of HLA-A9, HLA-11, and HLA-B13 in patients with otosclerosis compared with normal individuals strongly suggests a genetic, HLA-related component.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Singhal SK,Mann SB,Datta U,Panda NK,Gupta AKdoi
10.1016/s0196-0709(99)90019-4subject
Has Abstractpub_date
1999-03-01 00:00:00pages
102-5issue
2eissn
0196-0709issn
1532-818Xpii
S0196-0709(99)90019-4journal_volume
20pub_type
杂志文章abstract:PURPOSE:This study was performed to evaluate the usefulness of Hounsfield unit (HU) to better distinguish cholesteatoma from other inflammatory conditions in the mastoid ad antrum before primary mastoid surgery. MATERIALS AND METHODS:We enrolled 82 patients who underwent tympanomastoidectomy for treatment of chronic o...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2010.01.008
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:This study was done to determine the direct impact implementation of the Affordable Care Act (ACA) on patients with Head and Neck Cancer (HNCA) in states that chose to expand Medicaid compared to in states that did not, as well as assess whether this impact varied among different demographic groups. MATERIALS ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102464
更新日期:2020-01-01 00:00:00
abstract::Two cases of inner ear injury caused by suppressed sneezing are described. One patient experienced vestibular symptoms in the form of reflexogenic vertigo that was relieved by surgical section of the tensor tympani tendon. The other patient had a sudden severe permanent sensorineural hearing loss. It is proposed that ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(85)80027-2
更新日期:1985-11-01 00:00:00
abstract::Until recently, the prevailing view regarding the function of osteoblasts and osteoclasts was to attribute bone formation to the former and bone resorption to the latter. While the capacity of the osteoclast to degrade bone matrix remains unquestioned, there is now provocative evidence indicating that the osteoblast p...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(87)80044-3
更新日期:1987-09-01 00:00:00
abstract:PURPOSE:Obstructive sleep apnea is characterized by repetitive cessation of breathing during sleep. It affects different aspects of sexuality. We aimed to assess male sexual function & risk factors in obstructive sleep apnea patients. METHODS:This case control study included 2 groups, 45 healthy volunteers as control ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102899
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:Laryngeal squamous cell carcinoma (LSCC) is strongly associated with tobacco use, but recent reports suggest an increasing incidence of LSCC in patients without traditional risk factors, suggesting an alternative etiology of tumorigenesis. The purpose of this study is to characterize this non-smoking populat...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.11.009
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The pedicled nasoseptal mucoperiosteal flap is currently widely used for the reconstruction of a skull base defect following transsphenoidal surgery. The flap is generally secured in position by a Foley catheter balloon. We describe an alternative technique using cylinders of Gelfoam™ (Pfizer Incorporated) t...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102417
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the relationship between adenoid microbiology, adenoid size, and maxillary sinus microbiology in children with both chronic rhinosinusitis and adenoid hypertrophy. METHODS:The children with both chronic rhinosinusitis and adenoid hypertrophy were admitted to this pr...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2003.10.003
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:The objective of our randomized, double-blind study was to compare the effectiveness of intratympanic (IT) dexamethasone versus high-dosage of betahistine in the treatment of patients with intractable unilateral Meniere disease (MD). MATERIALS AND METHODS:Sixty six patients with definite unilateral MD were ran...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.amjoto.2014.10.032
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:To quantify the incidence of ear disease in patients infected with human immunodeficiency virus (HIV). MATERIALS AND METHODS:This is a descriptive case series of HIV-positive patients, with data collected using an otologic questionnaire. otologic examination, audiologic evaluation, and chart review. The study ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(00)80117-9
更新日期:2000-01-01 00:00:00
abstract::Profound unilateral sensorineural hearing loss is an indication for the placement of a bone anchored hearing aid. In a few unfortunate patients who later develop contralateral hearing loss, a cochlear implant becomes a good option. We present our experience in these cases and discuss our technique for single stage con...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2015.05.003
更新日期:2015-09-01 00:00:00
abstract::The bacteriology of acute otitis media in 18 children eight to 17 years of age was investigated through the use of culture of middle ear exudate obtained by tympanic membrane puncture. Equal numbers of children had either Hemophilus influenzae (six) or Streptococcus pneumoniae (six) in the middle ear exudate. Acute ot...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(81)80004-x
更新日期:1981-02-01 00:00:00
abstract:INTRODUCTION:In this study, we evaluate the effect of acyclovir in the treatment of recurrent respiratory papillomatosis (RRP), in addition to CO2 surgery. MATERIALS AND METHODS:We include 12 patients who had aggressive RRP and required at least three prior endoscopic surgeries in this study. Acyclovir treatment start...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(94)90007-8
更新日期:1994-05-01 00:00:00
abstract::Lateralization of bilaterally applied bone-conducted signals could be accomplished by variation of time (delta t) or intensity (delta I) differences between signals. The task was relatively easy with clicks and with tone pips with short rise times. When rise times were made longer than 1 msec the ability to localize d...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(82)80044-6
更新日期:1982-03-01 00:00:00
abstract:PURPOSE:The purpose of this retrospective cohort study was to determine whether there is a difference in the sensitivity of chest computed tomography (CT) versus 18F-fluorodeoxyglucose positron emission tomography with low-dose nonenhanced CT (18F-FDG PET/CT or PET/CT) in the detection of distant metastases in head and...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102662
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:In the literature, diabetes mellitus was mentioned as one of the etiologic factors of olfactory disorder. However, association between olfactory dysfunction and complications of type 2 diabetes mellitus is unclear. The aim of this study was to determine if there is any correlation between olfactory dysfuncti...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2019.102365
更新日期:2020-01-01 00:00:00
abstract::This case is a single submandibular gland mumps viral infection patient without parotid gland involvement who developed complications of meningitis and orchitis. Since spontaneous remission is common in mumps viral infection, missing opportunities for exact diagnosis is frequent. As in this case, single submandibular ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.02.004
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Three patients with otologic disorders developed complications related to hypercoagulability. This report was prepared to increase the awareness among otolaryngologists of the diagnosis and management of hypercoagulable states, and to encourage expert consultation when indicated. MATERIALS AND METHODS:One...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(93)90090-t
更新日期:1993-09-01 00:00:00
abstract::This case report describes a patient who was found to have a cerebrospinal fluid (CSF) leak originating from the petrous apex. The patient initially presented with multiple bouts of meningitis. The patient was treated surgically via a middle cranial fossa approach but presented five years later with recurrent meningit...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2014.02.013
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:Provide data to support expansion of FDA indications for the Bone anchored hearing system (BAHS). MATERIALS AND METHODS:This retrospective study in a tertiary otologic referral center included106 consecutive subjects who were implanted with a Bone Anchored Hearing System (BAHS) between January 2009 and January...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102864
更新日期:2021-01-05 00:00:00
abstract::Herpes simplex virus infection of the larynx is an exceedingly rare clinical entity, most frequently reported in the pediatric population or in immunocompromised adults. We present a 62-year-old woman presented with neck pain, hoarseness, crepitus over the larynx, and what appeared to be a necrotic mass of the right t...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2012.11.006
更新日期:2013-05-01 00:00:00
abstract:CASE:A 57year old female patient presented with a painful right-sided neck mass that on MRI was shown to be adherent to the posterior aspect of the sternocleidomastoid muscle. The mass was surgically resected en bloc without complications. Histopathologic analysis revealed the mass to be a myxoma. REVIEW:To date, ther...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2014.10.010
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:Patients with chronic otitis media with/without cholesteatoma present a significant challenge to safe cochlear implantation (CI). The aim of our study is to describe our experience and propose management options for CI in patients with chronic otitis media. STUDY DESIGN:Retrospective case study. SETTING:Ter...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2014.08.001
更新日期:2014-11-01 00:00:00
abstract:IMPORTANCE:Resident fatigue has become a point of emphasis in medical education and its effects on otolaryngology residents and their patients require further study. OBJECTIVE:The purpose of our study was to evaluate the prevalence and nature of fatigue in otolaryngology residents, evaluate various quality of life mea...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2016.01.017
更新日期:2016-05-01 00:00:00
abstract::Wegener granulomatosis is an immune-mediated, systemic vasculitis with unknown etiology that can be seen in almost any anatomical site. Positivity for antineutrophil cytoplasmic antigene, which is a serological marker, and presence of granulomatous vasculitis in histopathologic specimens from the lesions are accepted ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2007.04.007
更新日期:2008-03-01 00:00:00
abstract::Two cases of trisomy 18 in which temporal bone defects were limited to the inner ears are described. Several abnormalities were present that have not been described previously in this syndrome. The first case involved a 1-month-old female infant who died of congenital heart defects. Cochlear nerve fibers were absent o...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(85)80018-1
更新日期:1985-09-01 00:00:00
abstract::Substantial support for the concept that the posterior semicircular canal is responsible for benign paroxysmal positional vertigo comes from four sources: clinical observations, temporal bone histopathology, experimental observations, and results of selective denervation of the posterior canal crista (singular neurect...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(85)80042-9
更新日期:1985-03-01 00:00:00
abstract::Congenital agenesis of the sternum is an extremely unusual malformation rarely encountered by the practicing Otolaryngologist. It typically arises in conjunction with other midline ventral congenital anomalies, including abdominal, diaphragmatic, and cardiac malformations. We report a case series of two patients manag...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.04.010
更新日期:2010-09-01 00:00:00
abstract::The isotypic pattern of antipneumococcal polysaccharide antibodies with respect to IgG subclasses differs in adults and children. Adults show almost exclusively IgG2 activity, whereas children exhibit both IgG1 and IgG2 activity. The IgG subclass pattern of the antibody response after pneumococcal vaccination was eval...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(85)80055-7
更新日期:1985-07-01 00:00:00
abstract::The first case of the endoscopic intranasal excision of chondromyxoid fibroma as an outgrowth of the ethmoid bone is reported. This case appears to represent the second reported type of recurrence of CMF in the head and neck area and the second type of CMF originating in the ethmoid. ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(95)90105-1
更新日期:1995-05-01 00:00:00