Abstract：
:Until recently, the prevailing view regarding the function of osteoblasts and osteoclasts was to attribute bone formation to the former and bone resorption to the latter. While the capacity of the osteoclast to degrade bone matrix remains unquestioned, there is now provocative evidence indicating that the osteoblast plays a critical role in regulating osteoclast resorptive activity as well as in contributing directly to matrix dissolution. The first of these points follows from observations indicating that the osteoblast (but not the osteoclast) 1) exhibits receptors and/or responses to resorption-promoting agents (including parathyroid hormone and vitamin D), and 2) releases agents capable of stimulating bone resorption. The second point is derived from studies demonstrating that the osteoblast produces neutral collagenase (an enzyme specialized to degrade type I collagen, the principal organic constituent of bone matrix) and an inhibitor capable of blocking collagenase activity. The synthesis of both of these proteins is, in part, regulated by parathyroid hormone and other resorption-stimulating agents and appears to involve control at the transcriptional, translational, and secretory levels. Thus, in both physiologic bone remodeling and modeling, as well as the altered bone turnover associated with some disease states, it is the osteoblast rather than the osteoclast that may hold the key to understanding the mechanism of tissue form and function.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Kahn AJ,Partridge NCdoi
10.1016/s0196-0709(87)80044-3subject
Has Abstractpub_date
1987-09-01 00:00:00pages
258-64issue
5eissn
0196-0709issn
1532-818Xpii
S0196-0709(87)80044-3journal_volume
8pub_type
杂志文章,评审abstract：BACKGROUND:Cluster schedule of allergen-specific immunotherapy (AIT) is a cost-effective choice for allergic rhinitis (AR) patients, but its safety has been questioned due to the greater dosages required at each treatment compared with conventional immunotherapy. It remains a question that whether cluster schedule lead...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,meta分析
doi：10.1016/j.amjoto.2019.07.013
更新日期：2019-01-01 00:00:00
abstract：:A newly devised pupillograph that can record the pupillary responses of both eyes simultaneously in a supine subject is described. Three patients with Meniere's disease in the attack and quasiattack stages showed a similar abnormality of pupillary light contraction on the affected side, compared with the unaffected si...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80090-9
更新日期：1985-05-01 00:00:00
abstract：OBJECTIVE:Patients with chronic otitis media with/without cholesteatoma present a significant challenge to safe cochlear implantation (CI). The aim of our study is to describe our experience and propose management options for CI in patients with chronic otitis media. STUDY DESIGN:Retrospective case study. SETTING:Ter...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.08.001
更新日期：2014-11-01 00:00:00
abstract：CASE:A 57year old female patient presented with a painful right-sided neck mass that on MRI was shown to be adherent to the posterior aspect of the sternocleidomastoid muscle. The mass was surgically resected en bloc without complications. Histopathologic analysis revealed the mass to be a myxoma. REVIEW:To date, ther...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2014.10.010
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:Sir Charles Bell is renowned and revered as an outstanding surgeon, anatomist, clinician and teacher and his many contributions to various medical fields have been amply described. What are less well-known are his contributions to the field of laryngology. METHODS:Selected clinical and physiological publi...
journal_title：American journal of otolaryngology
pub_type： 传,历史文章,杂志文章,评审
doi：10.1016/j.amjoto.2017.04.011
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:The aim of this study was to compare the efficacy and safety of moxifloxacin with that of amoxicillin/clavulanate for the treatment of acute bacterial sinusitis in adults. MATERIALS AND METHODS:Five hundred seventy-five patients from Latin American countries were randomized to receive oral moxifloxacin 400 mg ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2006.06.016
更新日期：2007-03-01 00:00:00
abstract：:Starting eight days after hatching, chicks received daily subcutaneous injections of streptomycin sulfate, either 400 mg/kg for 30 days or 1,200 mg/kg for 15 days. Randomly selected chicks from each group were killed at intervals during the injection period, and the ampullae were examined for signs of vestibulotoxicit...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(84)80053-8
更新日期：1984-11-01 00:00:00
abstract：:An ancient Peruvian specimen (600 to 800 years old) with fibrous dysplasia involving the left frontoethmoidal region is discussed. The skull is that of a woman aged 20 to 30 years exhibiting marked deformity of the left frontal bone, ethmoids, orbit, and nasal wall. Plane radiographs and tomographic views demonstrate ...
journal_title：American journal of otolaryngology
pub_type： 历史文章,杂志文章
doi：10.1016/s0196-0709(80)80005-6
更新日期：1980-02-01 00:00:00
abstract：INTRODUCTION:A 10-year-old girl presented to the Emergency Department with temporomandibular joint pain, malocclusion, and trismus after a bicycle accident. METHODS:CT of the temporal bones showed displacement of the right mandibular condyle into the middle cranial fossa with small intraparenchymal hemorrhage. The con...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.11.004
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to report a recent case of mucoepidermoid carcinoma (MEC) of the thyroid, review the pertinent literature, and highlight the importance of multimodal treatment in this potentially aggressive malignancy. STUDY DESIGN:The study comprise a case report and a review of literature. METHO...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2004.08.014
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:Suspension laryngoscopy is a commonly performed procedure in otolaryngology. During the procedure, the laryngoscope applies direct force to the tongue. Postoperative tongue symptoms include pain, swelling, numbness, taste disturbance, and rarely motor deficits. Duration and magnitude of force applied have previ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102402
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:The aim of the study was to present a consecutive series of neonatal dacryocele with endonasal cyst diagnosed and treated in our institution and to compare our management regimen and outcome with those reported in the literature. METHODS:The study was conducted at a university-affiliated teaching hospital. Stu...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2009.11.009
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:To determine whether inclusion of chemoradiation history increases estimated risk for complications following total laryngectomy using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) Surgical Risk Calculator. MATERIALS AND METHODS:A retrospective review of 96 patients wit...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2017.11.005
更新日期：2018-01-01 00:00:00
abstract：:Volumetric changes of the middle ear and mastoid were measured monthly by the direct volumetric method in 28 ears from 21 patients (12 children and nine adults) with otitis media with effusion. The mean volumetric increase immediately after the insertion of the tubes was 1.56 ml and was attributed to the volume of eff...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(86)80053-9
更新日期：1986-07-01 00:00:00
abstract：:Type III frontal recess air cell as a cause of frontal sinus pneumocele has not been previously reported in literature. A 31-year-old woman with chronic history of sinusitis presented with pressure in the left eye on blowing the nose. Computed tomography examination of the orbits and paranasal sinuses with coronal and...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2009.01.001
更新日期：2010-05-01 00:00:00
abstract：PURPOSE:To determine the neurologic morbidity and oncologic effectiveness of carotid resection in patients with advanced squamous cell carcinoma of the head and neck. METHODS:A retrospective review of all published cases of squamous cell carcinoma of the head and neck treated by carotid resection was performed. RESUL...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,meta分析
doi：10.1016/0196-0709(92)90079-9
更新日期：1992-11-01 00:00:00
abstract：PURPOSE:Eustachian tube balloon dilation (ETBD) has been recently described as feasible treatment for patients with refractory Eustachian tube dysfunction (ETD). The aim of this study was to evaluate the efficacy of ETBD in the treatment of symptomatic Eustachian tube dysfunction (SETD) by subjective and objective anal...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2015.10.010
更新日期：2016-03-01 00:00:00
abstract：:Metastatic calcification (MC) commonly results secondary to phosphorus and calcium dysregulation in end-stage renal disease (ESRD). Only once before has MC been reported to involve a true vocal cord. A 35-year-old man with ESRD and secondary hyperparathyroidism was evaluated for hoarseness. Three years ago, he underwe...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.04.006
更新日期：2009-05-01 00:00:00
abstract：PURPOSE:To reach a consensus on the preoperative evaluation and management of intraoperative and postoperative tonsillectomy hemorrhage. METHOD:A survey on the preoperative evaluation and the management of intraoperative and postoperative tonsillectomy hemorrhage was given to one of the faculty members at each of the ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(95)90006-3
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:The aim of the study is to review the management of petrous apex cholesterol granuloma. The surgical approaches for drainage or total removal and the wait and see policy were analyzed, and outcomes were evaluated. METHODS:Retrospective charts of 27 patients managed for petrous apex cholesterol granuloma with...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.08.007
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:Few studies in the past decade have focused on antimicrobial resistance of bacteria in pediatric rhinosinusitis. This study aimed to characterize organisms cultured from pediatric chronic rhinosinusitis, as well as current resistance patterns of pathogens. MATERIALS AND METHODS:The study was conducted from Jan...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.11.014
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:Previous research has demonstrated the safety of tracheoesophageal puncture voice prosthesis (TEP) placement in radiated patients; however, there is a growing population of twice-radiated patients with limited research on the outcomes of TEP-placement in this cohort. METHODS:After Institutional Review Board ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2019.08.003
更新日期：2019-01-01 00:00:00
abstract：:Rupture of the carotid artery has been one of the most feared postoperative complications in head and neck cancer patients. Traditional management of carotid artery rupture has been disappointing, and morbidity and mortality have been high. Experience with carotid artery rupture at the authors' institution over the pa...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(86)80009-6
更新日期：1986-05-01 00:00:00
abstract：PURPOSE:To demonstrate non-inferiority of eberconazole 1% otic solution to clotrimazole 1% solution, and to compare their safety profiles in the treatment of otomycosis. MATERIALS AND METHODS:Multicenter, randomized, double-blind, active treatment-controlled phase 3 clinical trial. One hundred and ninety patients with...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.amjoto.2018.03.017
更新日期：2018-01-01 00:00:00
abstract：:Aneurysmal bone cyst is a rare lesion of the head and neck, and the mandible and maxilla are the most common sites of occurrence. To the authors' knowledge, two cases of aneurysmal bone cyst of the larynx described here are the first to be reported. Although the exact pathogenesis of this lesion is unknown, several th...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(86)80027-8
更新日期：1986-09-01 00:00:00
abstract：:We aimed to investigate the relationship between peripheral vertigo and inflammation by using the neutrophil-to-lymphocyte ratio (NLR) as an inflammatory marker. We recruited 103 patients with peripheral vertigo (71 women, 32 men; mean age, 39.8 ± 14.7 years) who presented to the Otolaryngology Department of Dumlupina...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.08.004
更新日期：2014-11-01 00:00:00
abstract：PURPOSE:Laryngeal papillomatosis is the most common benign tumor of the larynx of children. It is characterized by the development of exophytic proliferative lesions in the mucosa of the airways. Human papillomavirus (HPV) has been recognized as a causal agent among which HPV types 6 and 11 are the most frequently impl...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2019.02.003
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To determine differences in size of cochlear nerves among subjects with deafness due to connexin 26 (Cx26) mutations, subjects with deafness of unknown origin, and normal hearing subjects by sagittal high-resolution magnetic resonance (HRMR) imaging of the temporal bone. MATERIALS AND METHODS:Cross-sectional a...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2005.09.007
更新日期：2006-05-01 00:00:00
abstract：:Hemangiopericytomas are soft tissue tumors composed of pericytic cells that are characterized by their "staghorn" vascular branching and their variable clinical presentation. Fifteen to 25% of all HPC occur in the head and neck, with only 5% found in the nose or paranasal sinuses. Sinonasal hemangiopericytoma (SNHPC) ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2016.09.003
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:This study identifies how recurrent Zenker's diverticula are treated. METHODS:A retrospective chart review was performed from four tertiary referral academic voice and swallowing centers to identify individuals who underwent surgery for recurrent Zenker's diverticulum. Demographic data, surgical modalities f...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102755
更新日期：2021-01-01 00:00:00
