Abstract：
PURPOSE:The aim of this study was to compare the efficacy and safety of moxifloxacin with that of amoxicillin/clavulanate for the treatment of acute bacterial sinusitis in adults. MATERIALS AND METHODS:Five hundred seventy-five patients from Latin American countries were randomized to receive oral moxifloxacin 400 mg once daily for 7 days, or oral amoxicillin/clavulanate 500/125 mg 3 times daily for 10 days, in a prospective, open study. RESULTS:At the test-of-cure visit (7-14 days after the end of therapy), the clinical success rate in the moxifloxacin group was 93.4% similar to that in the amoxicillin/clavulanate group (92.7%). Documented bacteriological eradication plus presumed eradication rates in the moxifloxacin (96.5%) and the amoxicillin/clavulanate (96.7%) groups were also similar. Drug-related adverse events were recorded in 32.2% of patients in the moxifloxacin group and 29.7% in the amoxicillin/clavulanate group. Patient discontinuation in the trial due to adverse events occurred for 10 patients in the moxifloxacin group and 6 in the amoxicillin/clavulanate group. CONCLUSIONS:Overall, in terms of clinical and bacteriological response, moxifloxacin was equivalent to amoxicillin/clavulanate for the treatment of acute bacterial sinusitis in adults.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Arrieta JR,Galgano AS,Sakano E,Fonseca X,Amábile-Cuevas CF,Hernández-Oliva G,Vivar R,González G,Torres A,Moxifloxacin in Acute Sinusitis Study (MASS) Latin American Study Group.doi
10.1016/j.amjoto.2006.06.016subject
Has Abstractpub_date
2007-03-01 00:00:00pages
78-82issue
2eissn
0196-0709issn
1532-818Xpii
S0196-0709(06)00124-4journal_volume
28pub_type
杂志文章,随机对照试验abstract：PURPOSE:To report our long-term results in surgical management of invasive intralabyrinthine cholesteatoma. MATERIAL AND METHODS:The study is a case series in a tertiary referral center. Retrospective chart review of all mastoid operations performed for chronic ear disease between 1994 and 2019 at University Health Ne...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102407
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:The influence on balance by the peripheral vestibular disturbance in Ménière's disease is studied. The influence of visual and proprioceptive support in balance is evaluated. MATERIALS AND METHODS:Patients with recurrent spontaneous vertigo attacks (n = 134) were studied, 90 with Ménière's disease and 44 ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(93)90114-m
更新日期：1993-11-01 00:00:00
abstract：:Current indications for TT placement are (1) persistent SOM that has not responded to a 6 to 12-week course of medical treatment. This includes full and prophylactic doses of antimicrobials (and corticosteroids, as indicated); (2) recurrent AOM (at least three episodes in 6 months or four episodes in 12 months) that d...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/0196-0709(94)90058-2
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:The main limitation of fine-needle aspiration (FNA) is its limited distinction between neoplastic and benign lesions. We summarize our experience with thyroid nodules that were defined as follicular lesions by comparing the clinical and cytological features of the thyroid follicular lesions that were examine...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(03)00030-9
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:The standard treatment for patients with early glottic carcinoma in Israel has been radiotherapy. In recent years, encouraging results with laryngo-microscopic carbon dioxide laser surgery as a treatment for early glottic carcinoma has changed our treatment strategy. We conducted a retrospective study to invest...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2003.2
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:We aimed to attract our college's attention to the Melkersson-Rosenthal syndrome (MRS), which has been an infrequently encountered subject in otolaryngology journals during the last 10 years. MATERIALS AND METHODS:A retrospective review of the last 10 years' patient database was performed to find patients with...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.02.004
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:Cell adhesion molecules are cell surface proteins that allow specific cell-cell interactions among leukocytes, as well as between leukocytes and other cells. Because middle ear cholesteatoma is characterized by the presence of leukocyte infiltrates, the presence of the two molecule types of intercellular a...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(94)90094-9
更新日期：1994-07-01 00:00:00
abstract：PURPOSE:The aim of the study was to investigate the feasibility and effectiveness of botulinum toxin therapy in salivary secretory disorders. MATERIALS AND METHODS:We treated 24 patients with botulinum neurotoxin type A for drooling, salivary fistulas, sialoceles, recurrent parotitis, and Frey's syndrome; each parotid...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2007.10.003
更新日期：2008-09-01 00:00:00
abstract：:Branhamella catarrhalis has gained increasing recognition as a pathogen in the respiratory tract. During the past 18 years, since its transfer from the genus Neisseria, it has been associated with infection in cavities of the respiratory tract (sinuses and middle ear). It has been recognized as playing a role in laryn...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(91)90046-i
更新日期：1991-03-01 00:00:00
abstract：:Synchronous appearance of 2 different malignancies in one patient is a rare phenomenon. We describe our experience of 2 patients with synchronous malignancies of the testis and thyroid gland, and of a third patient who developed a thyroid neoplasm unrelated to recent treatment for a germ cell tumor. The medical record...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2000.18887
更新日期：2000-11-01 00:00:00
abstract：PURPOSE:To investigate the correlation between internet search activity and epistaxis-related Emergency Department visits. MATERIALS AND METHODS:Data from Google Trends were obtained (www.google.com/trends) for the search term "nosebleed" in Erie County, Pennsylvania during a five-year period. All epistaxis-related CP...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2018.07.012
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:This study was developed to test the hypothesis that intensive biofeedback and relaxation training may favorably affect chronic tinnitus. PATIENTS AND METHODS:Seven subjects with chronic tinnitus of moderate to severe intensity engaged in an intensive 5-month program of weekly, individual 90 minute sessions. A...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(92)90075-5
更新日期：1992-11-01 00:00:00
abstract：OBJECTIVES:Chronic rhinosinusitis (CRS) is a complicated disease with clinical symptoms that are impacted by the absence or presence of nasal polyps (CRSsNP or CRSwNP). Understanding of the different treatments of CRS is very significant in selecting appropriate therapies and preventing exacerbation relevant to this ch...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2019.102311
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:Some cochlear implant (CI) patients lose their residual hearing during surgery. Two factors that might play a role in residual hearing loss are the change in intracochlear hydraulic pressure and force on the cochlear wall during electrode insertion. The aim of this study is to investigate whether a difference i...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102859
更新日期：2020-12-29 00:00:00
abstract：PURPOSE:Provide data to support expansion of FDA indications for the Bone anchored hearing system (BAHS). MATERIALS AND METHODS:This retrospective study in a tertiary otologic referral center included106 consecutive subjects who were implanted with a Bone Anchored Hearing System (BAHS) between January 2009 and January...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102864
更新日期：2021-01-05 00:00:00
abstract：:Tuberculosis is known to affect almost every organ in the body, but its manifestations in the head and neck region are quite rare. A tuberculous retropharyngeal abscess is a very rare condition and can be the cause of oropharyngeal dysphagia. It is usually secondary to tuberculosis of the spine and has the potential o...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2011.06.006
更新日期：2012-03-01 00:00:00
abstract：:Meniere's disease is a peripheral audiovestibular disorder characterized by vertigo, hearing loss, tinnitus, and aural fullness. Management of these symptoms includes medical and surgical treatment. Many patients with Meniere's disease can be managed using nonablative therapy, such as intratympanic steroids and endoly...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2020.102817
更新日期：2021-01-01 00:00:00
abstract：INTRODUCTION:The endoscopic brow lift technique relies on brow mobilization and often soft fixation to the underlying calvarium. While the endoscopic brow lift has been used safely, there are anecdotal reports of cerebrospinal fluid leak. We sought to measure calvarial thickness to improve the safety of cranial fixatio...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.03.014
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:This study identifies how recurrent Zenker's diverticula are treated. METHODS:A retrospective chart review was performed from four tertiary referral academic voice and swallowing centers to identify individuals who underwent surgery for recurrent Zenker's diverticulum. Demographic data, surgical modalities f...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102755
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:Retraction pocket and extrusion of the ossicular prosthesis remain significant problems after tympanoplasty in cholesteatoma surgery. This study presents an alternative surgical technique with a total compact ossicular prosthesis including cartilage, wire, and temporalis fascia. MATERIALS AND METHODS:A total o...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2007.12.001
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:To further enhance and assess the ability to characterize middle ear effusion (MEE) using non-invasive ultrasound technology. MATERIALS AND METHODS:This is a prospective unblinded comparison study. Fifty-six children between the ages of 6 months and 17 years scheduled to undergo bilateral myringotomy with pres...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2012.08.005
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:Lymph node density(LND) has been shown to be a better prognosticator than conventional nodal classification to predict prognosis for squamous cell carcinoma(SCC) of the oral cavity. However, studies focusing on subsites of oral cancer are meager. The role of LND for buccal SCC was evaluated in this study. METH...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2017.05.001
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:Little is known about prognostic factors and treatment outcomes in young patients with anaplastic thyroid cancer (ATC). The goal of this study is to define the clinical features of this subgroup. MATERIAL AND METHODS:Patients age 55 or younger with either ATC or well-differentiated thyroid cancer (WDTC) with a...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.07.008
更新日期：2013-11-01 00:00:00
abstract：INTRODUCTION:Primary mitochondrial cytopathies include more than 40 different identified diseases that have varied genetic features. The common factor among these diseases is that the mitochondria are unable to effectively complete oxidative phosphorylation to generate energy. One in 5000 children per year in the Unite...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.04.008
更新日期：2009-05-01 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the vestibular functions and dual-task performances of individuals with noise induced hearing loss. MATERIALS AND METHODS:Fifty individuals with noise induced hearing loss and 25 healthy individuals were included in the study. Individuals with noise induced hearing loss we...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102665
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:The purpose of this retrospective cohort study was to determine whether there is a difference in the sensitivity of chest computed tomography (CT) versus 18F-fluorodeoxyglucose positron emission tomography with low-dose nonenhanced CT (18F-FDG PET/CT or PET/CT) in the detection of distant metastases in head and...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102662
更新日期：2020-01-01 00:00:00
abstract：:The cartilaginous columellar strut is a well established, commonly used graft in rhinoplasty which provides support and stability to the nasal base. The risk of such a graft is related to grafts designs, whereby the posterior aspect can cause clicking with movement across the anterior nasal spine. We present an additi...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2012.12.008
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:To assess malpractice claims related to the management of dizziness in otolaryngology in order to improve care and minimize the risk of litigation. MATERIALS AND METHODS:This is a retrospective review of the LexisNexis "Jury Verdicts and Settlements" database. All lawsuits and out of court adjudications relate...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2017.03.009
更新日期：2017-01-01 00:00:00
abstract：:Intralabyrinthine schwannomas are rare tumors of the distal ends of the cochlear and vestibular nerve. Their presence can be debilitating secondary to symptoms of hearing loss, vertigo, tinnitus, and imbalance. Currently, treatment to restore hearing in those who have become profoundly deaf is not attempted. Additiona...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.11.002
更新日期：2014-03-01 00:00:00
abstract：PURPOSE:The purpose of the study was to systematically explore the fire and burn risk associated with fiberoptic cables and electrosurgical devices. MATERIALS AND METHODS:A 300-W light source was connected to a standard gray fiberoptic light cable. The end of the cable was either rested atop or buried within a cotton ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2007.05.006
更新日期：2008-05-01 00:00:00
