Adenovirus p53 purging for human breast cancer stem cell products.

abstract：:10 patients with paroxysmal nocturnal hemoglobinuria were studied taking 109 normal subjects of the Cuban population as control group. 26 HLA antigens corresponding to loci A and B were studied in both groups. Phenotypical frequency of both groups were compared. No statistically significant increase was found for any ...

journal_title：Acta haematologica

authors： Ustariz CR,Arce S,Hernández P,Almaguer M,Pérez S,Ballester JM

更新日期：1980-01-01 00:00:00

abstract：:In a group of 56 patients with acute leukaemia, the relation between leukaemic cell motility and peripheral leukaemic cell count, degree of organomegaly, maturation and FAB classification was investigated. Cell motility was studied by means of directly observed motility and scoring of handmirror cells and anti-HLA-cap...

journal_title：Acta haematologica

authors： van der Weide M,Imandt LM,Langenhuijsen MM

更新日期：1988-01-01 00:00:00

abstract：:The thrombogenicity of prothrombin complex concentrates (PCCs) has been known as a risk factor since their first clinical use about 30 years ago. The development of in vivo models to define the thrombogenic components in PCCs was instrumental in providing a logical basis for selecting in vitro assays to screen for the...

journal_title：Acta haematologica

authors： MacGregor I,McLaughlin L,Drummond O,Prowse C,Ferguson J

更新日期：1995-01-01 00:00:00

abstract：:A comparative study of karyotypes, hematological variables and neutrophil alkaline phosphatase (NAP) was performed in 106 parents (53 couples) of children with free, homogeneous trisomy 21 and of 220 parents (110 couples) of normal children. In the parents of trisomy 21 children we found a significant increase of the ...

journal_title：Acta haematologica

authors： Grozdea J,Bourrouillou G,Mounie C,Colombies P

更新日期：1980-01-01 00:00:00

abstract：:This report describes a case of hairy cell leukemia (HCL) occurring with autoimmune chronic active hepatitis (CAH). A 74-year-old woman presented with typical clinical and histologic features of HCL for which splenectomy was performed. 2 years later she developed abnormal liver function tests due to auto-immune CAH. T...

journal_title：Acta haematologica

authors： Begley CG,Mackay IR,Bhathal PS

更新日期：1985-01-01 00:00:00

abstract：:The expression of the enzyme marker terminal deoxynucleotidyl transferase (TdT) was examined by immunofluorescence assay in the cells from 333 cases with various types and subtypes of leukemia or lymphoma. More than 90% of cALL and T-ALL, 70% of Null-ALL and 80% of pre-B-ALL were TdT-positive. One case in the commonly...

journal_title：Acta haematologica

authors： Drexler HG,Menon M,Minowada J

更新日期：1986-01-01 00:00:00

abstract：:Iron overload due to regular transfusions of packed red cells can cause multiple organ damage. Iron chelation therapy (ICT) is important in patients with aplastic anemia (AA) who require blood transfusions as supportive management. With the introduction of the oral iron chelator deferasirox, ICT has become more widely...

journal_title：Acta haematologica

authors： Lee SE,Yahng SA,Cho BS,Eom KS,Kim YJ,Lee S,Min CK,Kim HJ,Cho SG,Kim DW,Min WS,Park CW,Lee JW

更新日期：2013-01-01 00:00:00

abstract：:The case history of a 71-year-old woman with three episodes of a microangiopathic hemolytic anemia over a 22-year span is detailed. During the last episode a possible response of her thrombotic thrombocytopenic purpura (TTP)-like syndrome to the administration of intravenous immunoglobulin is documented. In retrospect...

journal_title：Acta haematologica

authors： Staszewski H,Colbourn D,Donovan V,Ludman H

更新日期：1989-01-01 00:00:00

abstract：:Acute megakaryoblastic leukemia is uncommon and comprises about 5% of acute nonlymphoid leukemias in the French-American-British classification. Cell lines from such leukemias are relatively rare with only about 8 reported in the literature. We established a cell line from a case of acute megakaryoblastic leukemia ari...

journal_title：Acta haematologica

authors： Skinnider LF,Pabello P,Zheng CY

更新日期：1997-01-01 00:00:00

abstract：:The clinical pattern of haemolysis associated with Donath-Landsteiner antibodies has undergone a change over the years. In the current study 13 patients developed the acute form of the disease whilst only 1 presented with the classical picture of chronic paroxysmal cold haemoglobinuria. The acute illness typically occ...

journal_title：Acta haematologica

authors： Sokol RJ,Hewitt S,Stamps BK

更新日期：1982-01-01 00:00:00

abstract：:The effect of 3 different detergents (Triton X-100, Lubrol WX and Nonidet) on brain thromboplastin was examined and compared with the solubilisation due to deoxycholate. The effect of deoxycholate is superior over that of the other examined detergents. Deoxycholate extracts thromboplastic activity from brain tissue to...

journal_title：Acta haematologica

authors： Bayer PM,Deutsch E

更新日期：1975-01-01 00:00:00

abstract：:Cardiac scintigraphy has been performed in 60 beta-thalassaemia major patients aged 8-35 years who received regular blood transfusions and subcutaneous desferrioxamine (DFX) chelation. Fifty-seven showed no clinical, radiological or electrocardiographic evidence of heart disease and 3 had clinically apparent cardiac f...

journal_title：Acta haematologica

authors： Aldouri MA,Wonke B,Hoffbrand AV,Flynn DM,Ward SE,Agnew JE,Hilson AJ

更新日期：1990-01-01 00:00:00

abstract：:Platelet aggregation induced in vitro with ADP, adrenalin and ristocetin was tested in 7 patients with megakaryoblastic leukemia (MKL). All patients had normal or high platelet counts and presented with hemorrhagic diathesis including purpura ecchymosis and epistaxis. Platelet morphology was grossly abnormal and elect...

journal_title：Acta haematologica

authors： Berrebi A,Vorst E,Shtalrid M,Resnitzky P,Nir E

更新日期：1984-01-01 00:00:00

abstract：:Pleural effusion in chronic lymphocytic leukemia (CLL) is a relatively rare phenomenon. We report a case of a pleural effusion associated with B-cell CLL but with predominantly reactive T lymphocytes in the effusion. A cell surface phenotype study showed that T lymphocytes predominated in the pleural effusion, althoug...

journal_title：Acta haematologica

authors： Miyahara M,Shimamoto Y,Sano M,Nakano H,Shibata K,Matsuzaki M

更新日期：1996-01-01 00:00:00

abstract：:Chromosomal aberrations in a case of atypic myeloproliferative syndrome are reported. The analysis was carried out on short-term cultures of sternal bone marrow with the ASG and fluorescence method. 90% of the metaphases studied showed pseudoliploidy: one of the chromosomes 12 was missing and one submedian marker chro...

journal_title：Acta haematologica

authors： Fleischmann T,Krizsa F

更新日期：1975-01-01 00:00:00

abstract：:The goal of the study was to investigate changes in expression of selected growth factors tentatively involved in regeneration of haematopoietic tissues (bone marrow and spleen) following cyclophosphamide (CY) damage in the mouse. The bone marrow (BM) and spleen were examined separately, since the regenerating pattern...

journal_title：Acta haematologica

authors： Psenák O,Sefc L,Sýkora V,Chang KT,Necas E

更新日期：2003-01-01 00:00:00

abstract：:Eleven patients with acute myeloid leukaemia (AML) in first complete remission (CR) were treated with alfa-2a-interferon (for short 'interferon') maintenance therapy, at a dose of 3 MU twice to thrice weekly subcutaneously. Adjustments were made to maintain neutrophil counts > 1 x 10(9)/l and platelet counts > 100 x 1...

journal_title：Acta haematologica

authors： McSweeney EN,Worman CP,Tsakona CP,Jewel AP,Hoffbrand AV,Milligan DW,Burnett AK,Lewis ML,Goldstone AH

更新日期：1993-01-01 00:00:00

abstract：:Bone marrow samples of 28 individuals with clinically benign and of 41 patients with malignant monoclonal gammopathy were analyzed for the total number of lymphoplasmocellular elements containing cytoplasmic immunoglobulins and for the monoclonal fraction of these cells. Monoclonal immunoglobulin components were deter...

journal_title：Acta haematologica

authors： Morell A,Maurer W,Skvaril F,Barandun S

更新日期：1978-01-01 00:00:00

abstract：:The detection of cellular antigens in bone marrow sections depends on the method of embedding, the nature of antigen and antibody, antigen retrieval techniques and the sensitivity of the immunohistochemical method. This study evaluated a fluorescyl-tyramide-enhanced immunostaining method on methyl-methacrylate-embedde...

journal_title：Acta haematologica

authors： Gaiser T,Bernhards J

更新日期：2007-01-01 00:00:00

abstract：:In a previous study, we evaluated efficacy of repeated antilymphocyte globulin (ALG) treatment for patients with severe aplastic anemia not responding to an initial ALG treatment or relapsing after initial response to ALG. We now searched in the same cohort of patients for differences between patients who responded to...

journal_title：Acta haematologica

authors： Viollier R,Tichelli A

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Despite encouraging reports concerning the declining prevalence of iron deficiency, this easily preventable disorder is still an existing problem in presumably developed regions. OBJECTIVE:To evaluate the prevalence of iron deficiency and relevant anemia in children residing in Northern Greece and to study ...

journal_title：Acta haematologica

authors： Gompakis N,Economou M,Tsantali C,Kouloulias V,Keramida M,Athanasiou-Metaxa M

更新日期：2007-01-01 00:00:00

abstract：:Thalidomide acts on the microenvironment of myelodysplastic syndromes (MDS) by influencing cytokine networks, and growing evidence supports thalidomide's usefulness in the management of haematological malignancies, such as MDS. The European Collaboration Group on Myelofibrosis with Myeloid Metaplasia reviewed patients...

journal_title：Acta haematologica

authors： Prentice HG,Sacchi S,Russell N

更新日期：2005-01-01 00:00:00

abstract：:A 12-year-old male of Chinese ancestry had life-long hemolytic anemia attributed to alpha-thalassemia. Restriction endonuclease mapping of his DNA revealed that in reality, he had three alpha-globin loci, but he was homozygous for pyruvate kinase deficiency. The new pyruvate kinase variant carried by this patient was ...

journal_title：Acta haematologica

authors： Beutler E,Forman L

更新日期：1983-01-01 00:00:00

abstract：:Although multiple myeloma (MM) remains an incurable disease, its treatment has improved over the past decade. This improvement has been at least in part due to the introduction of novel antimyeloma agents with new mechanisms of action, including those that target both myeloma cells and the tumor microenvironment, with...

journal_title：Acta haematologica

authors： Cibeira MT,Mercadal S,Arenillas L,Muntañola A,Salamero O,Bladé J

更新日期：2006-01-01 00:00:00

abstract：:A 28-year-old woman with Bence-Jones multiple myeloma (MM) presented with several osteolytic lesions and a massive bone marrow infiltration with mature plasmocytes. After 6 cycles of chemotherapy with melphalan and prednisone, the patient, in apparent clinical remission, underwent allogeneic bone marrow transplantatio...

journal_title：Acta haematologica

authors： Gallamini A,Buffa F,Bacigalupo A,Van Lint MT,Peralvo J,Pittaluga PA,Occhini D,Marmont AM

更新日期：1987-01-01 00:00:00

abstract：:A 26-year-old female with Ki-1-positive large-cell anaplastic lymphoma is reported. The neoplastic cells were phenotypically and genotypically of T cell origin. Initially, neoplastic cells invaded the skin and lymph nodes, and then invaded the sternal and vertebral bones, ribs and the iliopsoas muscle. Central nervous...

journal_title：Acta haematologica

authors： Tsukamoto N,Morita K,Maehara T,Mitsuhashi M,Karasawa M,Murakami H,Omine M,Naruse T,Yatabe H

更新日期：1992-01-01 00:00:00

abstract：:Neoplastic cells of 18 patients with multiple myeloma were studied using a panel of 6 monoclonal antibodies to B cells and monospecific antisera against the light chain types of immunoglobulin. OKT10 bound to the myeloma cells of all the patients, although only a small percentage of the cells reacted in 3 instances. M...

journal_title：Acta haematologica

authors： Katagiri S,Yonezawa T,Tamaki T,Kanayama Y,Kuyama J,Ohnishi M,Tsubakio T,Kurata Y,Tarui S

更新日期：1984-01-01 00:00:00

abstract：:A hemophilia B patient, seropositive for HIV antibodies since 1984, came to us in March 1989 with a severe necrotizing lesion of the nose. It was an erythematous lesion and looked like rhinophyma. Microbiological examination of the skin biopsy showed the presence of Cryptococcus neoformans. At the time of the study, t...

journal_title：Acta haematologica

authors： Mares M,Sartori MT,Carretta M,Bertaggia A,Girolami A

更新日期：1990-01-01 00:00:00

abstract：:B-cell chronic lymphocytic leukaemia (B-CLL) is characterized by a high frequency of infections, including those of viral aetiology. Previous reports have demonstrated a specific immunologic response to influenza virus vaccine in B-CLL patients with normal IgG levels. In this study, we have evaluated different immunop...

journal_title：Acta haematologica

authors： Marotta G,Bucalossi A,Galieni P,Bigazzi C,Nuti S,Valenzin PE,Bocchia M,Lauria F

更新日期：1998-01-01 00:00:00

abstract：:In 83 children with acute lymphoblastic leukaemia (ALL) the immunological phenotype of the lymphoblasts was determined using E rosetting, monoclonal anti-T cell sera, surface immunoglobulin staining and common ALL antiserum. The data were compared with acid alpha-naphthyl acetate esterase (ANAE) and acid phosphatase (...

journal_title：Acta haematologica

authors： Veerman AJ,Huismans DR,van Zantwijk CH

更新日期：1983-01-01 00:00:00