Attenuation by genistein of sodium-chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.

abstract：:We reported that tumor endothelial cells (TECs) differ from normal endothelial cells (NECs) in many aspects, such as gene expression profiles. Although CXCR7 is reportedly highly expressed in blood vessels of several tumors, its function in TECs is still unknown. To investigate this role, we isolated TECs from mouse t...

journal_title：International journal of cancer

authors： Yamada K,Maishi N,Akiyama K,Towfik Alam M,Ohga N,Kawamoto T,Shindoh M,Takahashi N,Kamiyama T,Hida Y,Taketomi A,Hida K

更新日期：2015-12-15 00:00:00

abstract：:The inhibitory effects of novel prodrugs, inclusion complexes of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid (GOFA) and auraptene (AUR) with beta-cyclodextrin (CD), on colon carcinogenesis were investigated using an azoxymethane (AOM)/dextran sodium sulfate (DSS) model. Male CD-1 (ICR) mice initiated wit...

journal_title：International journal of cancer

authors： Tanaka T,de Azevedo MB,Durán N,Alderete JB,Epifano F,Genovese S,Tanaka M,Tanaka T,Curini M

更新日期：2010-02-15 00:00:00

abstract：:Malignant lymphomas frequently develop in the pleural cavity of patients with long-standing pyothorax. The term pyothorax-associated lymphoma (PAL) has been proposed for this type of tumor. Most PALs are diffuse lymphomas of the B-cell type and contain Epstein-Barr virus (EBV) DNA. We have established 2 lymphoma cell ...

journal_title：International journal of cancer

authors： Kanno H,Yasunaga Y,Ohsawa M,Taniwaki M,Iuchi K,Naka N,Torikai K,Shimoyama M,Aozasa K

更新日期：1996-07-03 00:00:00

abstract：:Deregulation of cell survival pathways and resistance to apoptosis are widely accepted to be fundamental aspects of tumorigenesis. As in many tumours, the aberrant growth and survival of colorectal tumour cells is dependent upon a small number of highly activated signalling pathways, the inhibition of which elicits po...

journal_title：International journal of cancer

authors： Greenhough A,Patsos HA,Williams AC,Paraskeva C

更新日期：2007-11-15 00:00:00

abstract：:Physiological concentrations of insulin support the in vitro growth of LB T-cell lymphoma. We could not detect similar insulin dependence in other tumor cell lines. This study reports that insulin also enhances the growth of LB cells in vivo. Mice treated with Streptozotocin (SZ) developed partial resistance to LB lym...

journal_title：International journal of cancer

authors： Sharon R,Pillemer G,Ish-Shalom D,Kalman R,Ziv E,Berry EM,Naor D

更新日期：1993-03-12 00:00:00

abstract：:Long-term survival rates for advanced ovarian cancer patients have not changed appreciably over the past four decades; therefore, development of new, effective treatment modalities remains a high priority. Tumor Treating Fields (TTFields), a clinically active anticancer modality utilize low-intensity, intermediate fre...

journal_title：International journal of cancer

authors： Voloshin T,Munster M,Blatt R,Shteingauz A,Roberts PC,Schmelz EM,Giladi M,Schneiderman RS,Zeevi E,Porat Y,Bomzon Z,Urman N,Itzhaki A,Cahal S,Kirson ED,Weinberg U,Palti Y

更新日期：2016-12-15 00:00:00

abstract：:A continuous lymphoma cell line, BJAB, derived from the tumour of an exceptional African case of Burkitt's lymphoma, has previously been described. Unlike 97% of African BL cases studied, neither the original tumour cells nor the cell line contained detectable amounts of EBV (Epstein-Barr virus) DNA, nor did they expr...

journal_title：International journal of cancer

authors： Clements GB,Klein G,Povey S

更新日期：1975-07-15 00:00:00

abstract：:As a part of an assessment of the potential use of retinoids in preventive and adjuvant treatment of HNSCC, we examined the effects of beta-all-trans retinoic acid (RA) on the growth and cell-surface glycoconjugates of 2 HNSCC cell lines. These lines, designated 1483 and 183A, were established from an untreated patien...

journal_title：International journal of cancer

authors： Lotan R,Sacks PG,Lotan D,Hong WK

更新日期：1987-08-15 00:00:00

abstract：:Oncostatin M is a leukocyte product that has been reported to have anti-proliferative effects directly on melanoma and other cancer cell lines in vitro. However, its function(s) in cancers in vivo appears complex and its roles in cancer growth in lungs are unknown. Here, we show that OSM promotes marked growth of tumo...

journal_title：International journal of cancer

authors： Lauber S,Wong S,Cutz JC,Tanaka M,Barra N,Lhoták S,Ashkar A,Richards CD

更新日期：2015-02-15 00:00:00

abstract：:A hamster lymphoid cell line, HCT-2, transformed by human T-cell leukemia virus type I (HTLV-I) was serially transplanted for 9 passages in newborn hamsters. A total of 34 newborn hamsters inoculated intraperitoneally (i.p.) with 0.2-2 X 10(7) HCT-2 cells developed fatal lymphomas with dissemination to various organs ...

journal_title：International journal of cancer

authors： Eguchi T,Kubonishi I,Daibata M,Yano S,Imamura J,Ohtsuki Y,Miyoshi I

更新日期：1988-06-15 00:00:00

abstract：:A case of epidermodysplasia verruciformis in a patient from Upper-Volta is described. Slightly elevated, flat warts were observed on hands, feet, arms and legs, and pityriasis versicolor-like lesions were found mainly on the trunk. The patient showed no malignant tumors. Histological examination revealed hyperkeratosi...

journal_title：International journal of cancer

authors： Pfister H,Nürnberger F,Gissmann L,zur Hausen H

更新日期：1981-05-15 00:00:00

abstract：:Signal transducer and activator of transcription 3 (STAT3) is activated in a variety of human cancers, including ovarian cancer. The molecular mechanism by which the STAT3 is activated in cancer cells is poorly understood. We observed that human ovarian xenograft tumors (A2780) in mice were severely hypoxic (pO(2) app...

journal_title：International journal of cancer

authors： Selvendiran K,Bratasz A,Kuppusamy ML,Tazi MF,Rivera BK,Kuppusamy P

更新日期：2009-11-01 00:00:00

abstract：:Using nationwide Danish registries we examined the long-term risk of cervical cancer in women diagnosed with cervical intraepithelial neoplasia grade 3 (CIN3) (including adenocarcinoma in situ (AIS)) on the cone compared to women with a normal cytology test. Initially, we identified women born 1918-1990, who were reco...

journal_title：International journal of cancer

authors： Sand FL,Frederiksen K,Munk C,Jensen SM,Kjaer SK

更新日期：2018-05-01 00:00:00

abstract：:In the 7th edition of the AJCC staging system, the mitotic rate criterion replaced Clark level to increase correct classification of high-risk thin melanoma patients (pT1B). Additionally, sentinel node biopsy (SNB) was recommended for nodal staging of pT1B melanomas. The aim of this article was to evaluate the effects...

journal_title：International journal of cancer

authors： Oude Ophuis CM,Louwman MW,Grünhagen DJ,Verhoef K,van Akkooi AC

更新日期：2017-04-15 00:00:00

abstract：:The expression of the Wilms tumor suppressor gene WT1 is largely restricted to elements of the developing urogenital system. In the fetal kidney, WT1 transcripts are present at low levels in the condensing mesenchyme and at much higher levels in differentiating glomerular epithelium and are not detected in other mesen...

journal_title：International journal of cancer

authors： Campbell CE,Kuriyan NP,Rackley RR,Caulfield MJ,Tubbs R,Finke J,Williams BR

更新日期：1998-10-05 00:00:00

abstract：:The impact of screening by visual inspection with acetic acid (VIA), cytology or HPV testing on cervical cancer incidence and mortality is investigated in a cluster randomized controlled trial in India. We report findings after the screening phase, when 52 clusters, with a total of 142,701 women aged 30-59 years in Os...

journal_title：International journal of cancer

authors： Sankaranarayanan R,Nene BM,Dinshaw KA,Mahe C,Jayant K,Shastri SS,Malvi SG,Chinoy R,Kelkar R,Budukh AM,Keskar V,Rajeshwarker R,Muwonge R,Kane S,Parkin DM,Chauhan MK,Desai S,Fontaniere B,Frappart L,Kothari A,Lucas E

更新日期：2005-09-10 00:00:00

abstract：:To understand the mechanisms underlying increased expression of Myc protein in human urinary bladder cancer, expression of c-myc mRNA and the copy number of the c-myc gene were determined. Expression of mRNA was measured by quantitative RT-PCR in 40 urothelial carcinomas and in 18 histologically normal mucosae. Mean e...

journal_title：International journal of cancer

authors： Christoph F,Schmidt B,Schmitz-Dräger BJ,Schulz WA

更新日期：1999-04-20 00:00:00

abstract：:High-grade serous epithelial ovarian cancer (HGS-EOC) is a systemic disease, with marked intra and interpatient tumor heterogeneity. The issue of spatial and temporal heterogeneity has long been overlooked, hampering the possibility to identify those genomic alterations that persist, before and after therapy, in the g...

journal_title：International journal of cancer

authors： Ballabio S,Craparotta I,Paracchini L,Mannarino L,Corso S,Pezzotta MG,Vescio M,Fruscio R,Romualdi C,Dainese E,Ceppi L,Calura E,Pileggi S,Siravegna G,Pattini L,Martini P,Delle Marchette M,Mangioni C,Ardizzoia A,Pelleg

更新日期：2019-11-15 00:00:00

abstract：:Retinoids modulate several cell functions and especially inhibit the growth of a wide variety of cells including breast cancer. Retinoic acid receptor-gamma (RAR-gamma) has been shown to mediate the antiproliferative activity of retinoids. To further test this hypothesis we examined the effects of different RAR-gamma ...

journal_title：International journal of cancer

authors： Widschwendter M,Daxenbichler G,Culig Z,Michel S,Zeimet AG,Mörtl MG,Widschwendter A,Marth C

更新日期：1997-05-02 00:00:00

abstract：:Adequate consumption of folate may reduce the risk of colorectal cancer. We performed a meta-analysis of 7 cohort and 9 case-control studies that examined the association between folate consumption and colorectal cancer risk. In cohort studies, the association between folate consumption and colorectal cancer risk was ...

journal_title：International journal of cancer

authors： Sanjoaquin MA,Allen N,Couto E,Roddam AW,Key TJ

更新日期：2005-02-20 00:00:00

abstract：:Allogeneic mixed leukocytes reaction has been reported to activate vast numbers of T lymphocytes and produce large amounts of type 1 cytokines that are linked to an initiation of antitumor immunity. Using poor immunogeneic B16-F10 and Lewis lung carcinoma (LLC) tumor model, we evaluated the effects of inactivated allo...

journal_title：International journal of cancer

authors： Su X,Guo S,Zhou C,Wang D,Ma W,Zhang S

更新日期：2009-03-01 00:00:00

abstract：:Although the incidence of, and deaths due to, malignant melanoma are rising at a rapid rate, few experimental models mimic the highly metastatic properties associated with the pathogenesis of the human disease, making study of the disease difficult. Thus, new human models are required to understand melanoma biology, e...

journal_title：International journal of cancer

authors： Welch DR,Bisi JE,Miller BE,Conaway D,Seftor EA,Yohem KH,Gilmore LB,Seftor RE,Nakajima M,Hendrix MJ

更新日期：1991-01-21 00:00:00

abstract：:Although heparin can regulate angiogenesis, tumor growth and metastasis, its clinical application, as well as that of low-molecular heparin (LMWH), for treating cancer are limited because of heparin's anticoagulant activity and risk of hemorrhages. LMWH-taurocholate conjugates (LHT7), which have low anticoagulant acti...

journal_title：International journal of cancer

authors： Lee E,Kim YS,Bae SM,Kim SK,Jin S,Chung SW,Lee M,Moon HT,Jeon OC,Park RW,Kim IS,Byun Y,Kim SY

更新日期：2009-06-15 00:00:00

abstract：:The melanosomal protein TRP2 expressed by melanocytes and most melanoma cells is an attractive, clinically relevant model antigen for the experimental development of melanoma immunotherapy in mice. A peptide shared by murine and human TRP2 can be recognized by melanoma-reactive CTL in C57BL/6 mice, as well as in human...

journal_title：International journal of cancer

authors： Steitz J,Brück J,Steinbrink K,Enk A,Knop J,Tüting T

更新日期：2000-04-01 00:00:00

abstract：:The aim of this study was to construct bispecific F(ab')2 [anti-CD3 x anti-BCL1 idiotype (Id)] Abs (BsAbs) which would enable lymphokine-activated killer (LAK) T cells to kill Id+ mouse BCL1 lymphoma cells, and to determine the mechanism(s) underlying cell death. Using 4-day activated LAK T cells from either perforin-...

journal_title：International journal of cancer

authors： Armstrong JM,Vitetta ES

更新日期：1996-12-11 00:00:00

abstract：:Loss of imprinting (LOI) of insulin-like growth factor 2 (IGF2) is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic IGF2 expression correlates strongly with the hypomethylation of a differentially methylated region (DMR) near its promoter. It has also been ...

journal_title：International journal of cancer

authors： Cheng YW,Idrees K,Shattock R,Khan SA,Zeng Z,Brennan CW,Paty P,Barany F

更新日期：2010-08-01 00:00:00

abstract：:The development of reliable gene expression profiling technology is having an increasing impact on our understanding of lung cancer biology. Our study aimed to determine any correlation between the phenotypic heterogeneity and genetic diversity of lung cancer. Microarray analysis was performed on a set of 46 tumor sam...

journal_title：International journal of cancer

authors： Sanchez-Palencia A,Gomez-Morales M,Gomez-Capilla JA,Pedraza V,Boyero L,Rosell R,Fárez-Vidal ME

更新日期：2011-07-15 00:00:00

abstract：:Seven-day-old mouse embryos were transplanted under the kidney capsule of adult syngeneic recipients which were either X-irradiated, treated with cyclophosphamide, splenectomized or immunized with teratocarcinoma cell lines prior to embryonic transplantation. The yield of malignant tumors was decreased in preirradiate...

journal_title：International journal of cancer

authors： Damjanov I,Bagasra O,Dominis M,Solter D

更新日期：1982-12-15 00:00:00

abstract：:In advanced cancer patients, the oxidative stress could take place either at the onset of disease or as a function of disease progression. To test this hypothesis, the following parameters were investigated: the erythrocyte activity of the enzymes superoxide dismutase (SOD) and glutathione peroxidase (GPx), the serum ...

journal_title：International journal of cancer

authors： Mantovani G,Macciò A,Madeddu C,Mura L,Gramignano G,Lusso MR,Mulas C,Mudu MC,Murgia V,Camboni P,Massa E,Ferreli L,Contu P,Rinaldi A,Sanjust E,Atzei D,Elsener B

更新日期：2002-03-01 00:00:00

abstract：:The E5 oncoprotein of human papillomavirus type 16 downregulates surface MHC Class I and interacts with the heavy chain of the MHC complex via the first hydrophobic domain, believed to form the first helical transmembrane region (TM1) of E5. TM1 contains 4 equally spaced di-leucine (LL1-LL4) motifs. Di-leucine motifs ...

journal_title：International journal of cancer

authors： Cortese MS,Ashrafi GH,Campo MS

更新日期：2010-04-01 00:00:00