Characterization of a human papillomavirus from epidermodysplasia verruciformis lesions of a patient from Upper-volta.

abstract：:The human tumor line LOX was established as an s.c. xenograft in nude mice from a lymph-node metastasis of a patient with malignant melanoma. I.v. injection into adult nude mice of single-cell suspensions prepared from xenografts resulted in progressively growing lung tumor colonies that killed the animals. No differe...

journal_title：International journal of cancer

authors： Fodstad O,Aamdal S,McMenamin M,Nesland JM,Pihl A

更新日期：1988-03-15 00:00:00

abstract：:Risk factors for pancreatic cancer, other than smoking and diabetes, are not well-established, especially for women. In a cohort of 1.3 million middle-aged women, followed for 9.2 million person-years for cancer incidence and 11.5 million person-years for mortality, there were 1,338 incident pancreatic cancer cases an...

journal_title：International journal of cancer

authors： Stevens RJ,Roddam AW,Spencer EA,Pirie KL,Reeves GK,Green J,Beral V,Million Women Study Collaborators.

更新日期：2009-05-15 00:00:00

abstract：:The treatment of human peripheral blood mononuclear cells (PBMC) with micromolar concentrations of SV-IV, a major protein secreted from the rat seminal vesicle epithelium, promotes in this cell population a marked cytotoxic activity against the Raji lymphoblastoid cell line. This activity is apparently due to cell-to-...

journal_title：International journal of cancer

authors： Peluso G,Marchese M,Furgi A,Ranieri M,Russo Spena S,Ravagnan G,Fuggetta MP,Porta R,Metafora V,Metafora S

更新日期：1997-07-17 00:00:00

abstract：:When sensitized leukocytes were re-exposed to EBV antigen or to tuberculin-purified protein derivatives, they produced lymphokines, including the migration inhibition factor, which inhibited the migration of guinea-pig peritoneal exudate cells, and other lymphokines with the characteristics of interferon, which inhibi...

journal_title：International journal of cancer

authors： Lai PK,Alpers MP,MacKay-Scollay EM

更新日期：1977-07-15 00:00:00

abstract：:We have previously reported that the negative signaling regulator Similar Expression to FGF (hSef) is downregulated in prostate cancer and its loss is associated with clinical metastasis. Here, we explored the mechanistic basis of this finding. We first confirmed our clinical observation by testing hSef manipulation i...

journal_title：International journal of cancer

authors： Hori S,Wadhwa K,Pisupati V,Zecchini V,Ramos-Montoya A,Warren AY,Neal DE,Gnanapragasam VJ

更新日期：2017-04-15 00:00:00

abstract：:Our study directly compares the performance of liquid-based (LBC) and conventional cytology for detecting high-grade cervical intraepithelial neoplasia and cancer (CIN 2+) in high-risk, previously unscreened women. As part of a larger randomized clinical trial assessing the efficacy and safety of a "screen and treat" ...

journal_title：International journal of cancer

authors： Taylor S,Kuhn L,Dupree W,Denny L,De Souza M,Wright TC Jr

更新日期：2006-02-15 00:00:00

abstract：:Melanoma-associated germline mutations affecting the tumor suppressor and cyclin-dependent kinase (CDK) inhibitor, CDKN2A/p16INK4a, have been identified in over 100 melanoma-prone families worldwide. To predict the melanoma risk for carriers of specific mutations, mutant p16INK4a can be tested in biochemical and cellu...

journal_title：International journal of cancer

authors： Becker TM,Ayub AL,Kefford RF,Mann GJ,Rizos H

更新日期：2005-11-20 00:00:00

abstract：:Circadian disruption has been classified as probably carcinogenic to humans by the World Health Organization's International Agency for Research on Cancer. The circadian clock is subject to environmental factors, particularly light exposure and food intake rhythms. However, the association between nutritional circadia...

journal_title：International journal of cancer

authors： Srour B,Plancoulaine S,Andreeva VA,Fassier P,Julia C,Galan P,Hercberg S,Deschasaux M,Latino-Martel P,Touvier M

更新日期：2018-11-15 00:00:00

abstract：:The population of Leningrad suffered from severe starvation, cold and psychological stress during the siege in World War II in 1941-1944. We investigated the long-term effects of the siege on cancer mortality in 3,901 men and 1,429 women, born between 1910 and 1940. All study subjects were residents of St. Petersburg,...

journal_title：International journal of cancer

authors： Koupil I,Plavinskaja S,Parfenova N,Shestov DB,Danziger PD,Vågerö D

更新日期：2009-03-15 00:00:00

abstract：:The authors reported in a previous study that NK012, a 7-ethyl-10-hydroxy-camptothecin (SN-38)-releasing nano-system, exhibited high antitumor activity against human colorectal cancer xenografts. This study was conducted to investigate the advantages of NK012 over irinotecan hydrochloride (CPT-11) administered in comb...

journal_title：International journal of cancer

authors： Nakajima TE,Yasunaga M,Kano Y,Koizumi F,Kato K,Hamaguchi T,Yamada Y,Shirao K,Shimada Y,Matsumura Y

更新日期：2008-05-01 00:00:00

abstract：:Invasion of malignant cells requires altered cellular interaction with extracellular matrix. Integrin-type cell adhesion receptors play an important role in this process. Integrin-related cell biological phenomena explain cancer cell migration, and recent developments in the field have made it possible to propose that...

journal_title：International journal of cancer

authors： Heino J

更新日期：1996-03-15 00:00:00

abstract：:The myxobacterial agent archazolid inhibits the vacuolar proton pump V-ATPase. V-ATPases are ubiquitously expressed ATP-dependent proton pumps, which are known to regulate the pH in endomembrane systems and thus play a crucial role in endo- and exocytotic processes of the cell. As cancer cells depend on a highly activ...

journal_title：International journal of cancer

authors： Kubisch R,Fröhlich T,Arnold GJ,Schreiner L,von Schwarzenberg K,Roidl A,Vollmar AM,Wagner E

更新日期：2014-05-15 00:00:00

abstract：:Androgen receptor (AR) mutations that modify both the ligand binding and the transactivation capacities of the AR represent one of the mechanisms involved in the transition of prostate cancer (PCa) from androgen-dependent to androgen-independent growth. We use a yeast-based functional assay to detect and analyze mutan...

journal_title：International journal of cancer

authors： Céraline J,Cruchant MD,Erdmann E,Erbs P,Kurtz JE,Duclos B,Jacqmin D,Chopin D,Bergerat JP

更新日期：2004-01-01 00:00:00

abstract：:In vitro infection of EBV-negative lymphoma cell lines with immortalizing strains of Epstein-Barr virus induces the cell-surface expression of B-cell markers, such as the EBV receptor/CR2 (CD21) and the CD23 antigen. The non-immortalizing EBV variant, P3HRI, which carries a deletion encompassing the EBV nuclear antige...

journal_title：International journal of cancer

authors： Calender A,Cordier M,Billaud M,Lenoir GM

更新日期：1990-10-15 00:00:00

abstract：:The MDR1 gene product P-glycoprotein (Pgp) plays a key role in multidrug resistance of cancer cells. Pgp is an ATP-driven efflux pump that extrudes a variety of dissimilar hydrophobic cytotoxic compounds. P-glycoprotein overexpression results in multidrug resistance (MDR) of tumor cell lines in vitro as well as in can...

journal_title：International journal of cancer

authors： Niv R,Assaraf YG,Segal D,Pirak E,Reiter Y

更新日期：2001-12-15 00:00:00

abstract：:NK cell recognition of tumor cells is mediated by a delicate balance of signals received by MHC class I-binding inhibitory NK cell receptors and activating NK cell receptors, which mainly bind to virus-, stress- or tumor-induced ligands. In addition, adhesion molecules such as the intercellular adhesion molecule-1 (IC...

journal_title：International journal of cancer

authors： Textor S,Accardi R,Havlova T,Hussain I,Sylla BS,Gissmann L,Cerwenka A

更新日期：2011-03-01 00:00:00

abstract：:Malignant tumors are generally characterized by extensive local tissue invasion and destruction of ECM which may be due to increased constitutive expression and activity of secreted proteases. Moreover, a large number of diverse protease activities may be constitutively over-expressed in a simultaneous or co-ordinated...

journal_title：International journal of cancer

authors： Korczak B,Kerbel RS,Dennis J

更新日期：1991-06-19 00:00:00

abstract：:Leukemic stem cells (LSC) might be the source for leukemic disease self-renewal and account for disease relapse after treatment, which makes them a critical target for further therapeutic options. We investigated the role of cytotoxic T-lymphocytes (CTL) counteracting and recognizing LSC. Leukemia-associated antigens ...

journal_title：International journal of cancer

authors： Schneider V,Zhang L,Rojewski M,Fekete N,Schrezenmeier H,Erle A,Bullinger L,Hofmann S,Götz M,Döhner K,Ihme S,Döhner H,Buske C,Feuring-Buske M,Greiner J

更新日期：2015-11-01 00:00:00

abstract：:Progression from an androgen-dependent to an androgen-independent state often occurs in patients with prostate cancer (PCa) who undergo hormonal therapy. We have investigated whether inhibition of the epidermal growth factor receptor (EGFR) signaling pathway affects the antitumor effect of a nonsteroidal antiandrogen....

journal_title：International journal of cancer

authors： Festuccia C,Gravina GL,Angelucci A,Millimaggi D,Muzi P,Vicentini C,Bologna M

更新日期：2005-07-01 00:00:00

abstract：:Multiple drug resistance (MDR) is a problem that seriously reduces the efficacy of many chemotherapy agents. One mechanism for MDR is increased acidification of endocytic vesicles and increased cytosol pH, so weak base chemotherapeutic agents, including doxorubicin, are trapped in endocytic vesicles and exhibit a drug...

journal_title：International journal of cancer

authors： Lou PJ,Lai PS,Shieh MJ,Macrobert AJ,Berg K,Bown SG

更新日期：2006-12-01 00:00:00

abstract：:Animal and experimental data suggest that anti-Müllerian hormone (AMH) serves as a marker of ovarian reserve and inhibits the growth of ovarian tumors. However, few epidemiologic studies have examined the association between AMH and ovarian cancer risk. We conducted a nested case-control study of 302 ovarian cancer ca...

journal_title：International journal of cancer

authors： Jung S,Allen N,Arslan AA,Baglietto L,Barricarte A,Brinton LA,Egleston BL,Falk RT,Fortner RT,Helzlsouer KJ,Gao Y,Idahl A,Kaaks R,Krogh V,Merritt MA,Lundin E,Onland-Moret NC,Rinaldi S,Schock H,Shu XO,Sluss PM,Staa

更新日期：2018-01-15 00:00:00

abstract：:Oncogenic HPV types are the major cause of worldwide cervical cancer, but only a small proportion of infected women will develop high-grade cervical intraepithelial neoplasia or cancer (CIN2/3+). We performed a prospective study including 781 women with normal, atypical squamous cells of undetermined significance (ASC...

journal_title：International journal of cancer

authors： Dalstein V,Riethmuller D,Prétet JL,Le Bail Carval K,Sautière JL,Carbillet JP,Kantelip B,Schaal JP,Mougin C

更新日期：2003-09-01 00:00:00

abstract：:Smoking and second-hand smoke (SHS) exposure have been recently linked to a higher risk of breast cancer in women. The aim of this work is to estimate the number of deaths and disability-adjusted life years (DALYs) from breast cancer attributable to these two risk factors in the European Union (EU-28) in 2017. The com...

journal_title：International journal of cancer

authors： Carreras G,Lachi A,Boffi R,Clancy L,Gallus S,Fernández E,López MJ,Soriano JB,López Nicolás Á,Semple S,Behrakis P,Gorini G,TackSHS Project Investigators.

更新日期：2020-11-01 00:00:00

abstract：:Although cervical cancer (CC) is a leading cause of cancer-related deaths in developing countries, incidence rates vary considerably, ranging from 3 to 61 per 10(5) females. Identifying determinants of high vs. low rates may suggest population-level prevention strategies. CC rates for 175 countries were obtained from ...

journal_title：International journal of cancer

authors： Drain PK,Holmes KK,Hughes JP,Koutsky LA

更新日期：2002-07-10 00:00:00

abstract：:The effects of galanin on pancreatic carcinogenesis induced by azaserine and on the norepinephrine concentration in the pancreas were investigated in male Wistar rats. Rats were given weekly injections of 10 mg/kg body weight of azaserine for 25 weeks and 8 microg/kg body weight of galanin in depot form every other da...

journal_title：International journal of cancer

authors： Iishi H,Tatsuta M,Baba M,Yano H,Iseki K,Uehara H,Nakaizumi A

更新日期：1998-01-30 00:00:00

abstract：:Although multiple myeloma (MM) is predominantly a disease of the elderly, few studies have focused on the identification of prognostic factors in this group of patients. Four hundred twenty five MM patients >65 years were uniformly treated with chemotherapy (MP or VCMP/VBAD). Multivariate analysis identified 4 factors...

journal_title：International journal of cancer

authors： García-Sanz R,González-Fraile MI,Mateo G,Hernández JM,López-Berges MC,de las Heras N,Fernández-Calvo J,Ortega F,Portero JA,Bárez A,Galende J,Orfão A,San Miguel JF

更新日期：2004-12-10 00:00:00

abstract：:Cancer Procoagulant (CP), a cysteine proteinase which triggers blood coagulation by directly activating Factor X (FX) in the absence of Factor VII (F VII), has recently been isolated from rabbit V2 carcinoma and biochemically characterized. We have studied the procoagulant activity of tissue extracts from 4 murine exp...

journal_title：International journal of cancer

authors： Falanga A,Bolognese Dalessandro AP,Casali B,Roncaglioni MC,Donati MB

更新日期：1987-06-15 00:00:00

abstract：:Marked variation in phenotypic expression among BRCA1 and BRCA2 mutation carriers may be partly explained by modifier genes that influence mutation penetrance. Variation in CAG/CAA repeat lengths coding for stretches of glutamines in the C-terminus of the AIB1 protein (amplified in breast cancer 1, a steroid receptor ...

journal_title：International journal of cancer

authors： Hughes DJ,Ginolhac SM,Coupier I,Barjhoux L,Gaborieau V,Bressac-de-Paillerets B,Chompret A,Bignon YJ,Uhrhammer N,Lasset C,Giraud S,Sobol H,Hardouin A,Berthet P,Peyrat JP,Fournier J,Nogues C,Lidereau R,Muller D,Fricke

更新日期：2005-11-01 00:00:00

abstract：:The independent effects of parity and age at first birth on breast cancer incidence are investigated in a 1% sample of women aged 16 to 59 from the 1971 Census of England and Wales. Over the period 1971-81, 1,003 breast cancer cases occurred in the cohort of 113,263 women who were either married, widowed or divorced a...

journal_title：International journal of cancer

authors： Leon DA

更新日期：1989-06-15 00:00:00

abstract：:The MLN64 gene, which is localized in q12-q21 of the human chromosome 17, encodes a novel protein containing 2 distinct domains. At the N-terminal, MLN64 exhibits a potential trans-membrane region, while at the C-terminal, it shares homology with the F26F4.4 protein of Coenorhabditis elegans and the steroidogenic acut...

journal_title：International journal of cancer

authors： Moog-Lutz C,Tomasetto C,Régnier CH,Wendling C,Lutz Y,Muller D,Chenard MP,Basset P,Rio MC

更新日期：1997-04-10 00:00:00