Abstract：
:The frequencies of ATG triplets in the genomes of various species were systematically analyzed, and the frequency of ATG triplets was significantly low around start codons in both prokaryotic and eukaryotic genomes. In eukaryotes, however, the frequency decrease before the start codon is much more evident than that after the start codon. In prokaryotes, on the other hand, the ATG frequency pattern around the start codon is less evident, and-more importantly-symmetric. We also computed average distances between a start codon and its nearest upstream-located ATG triplet and found a general tendency for the average distances to be longer in higher organisms.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Saito R,Tomita Mdoi
10.1007/pl00006460subject
Has Abstractpub_date
1999-02-01 00:00:00pages
213-7issue
2eissn
0022-2844issn
1432-1432journal_volume
48pub_type
杂志文章abstract：:As illustrated by the mitochondrion and the eukaryotic cell, little in biology makes sense except in light of mutualism. Mutualisms are persistent, intimate, and reciprocal exchanges; an organism proficient in obtaining certain benefits confers those on a partner, which reciprocates by conferring different benefits. M...
journal_title：Journal of molecular evolution
pub_type： 杂志文章,评审
doi：10.1007/s00239-017-9804-x
更新日期：2017-08-01 00:00:00
abstract：:We have performed a genome-wide analysis of the mimp family of miniature inverted-repeat transposable elements, taking advantage of the recent release of the F. oxysporum genome sequence. Using different approaches, we detected 103 mimp elements, corresponding to 75 nonredundant copies, half of which are located on a ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-008-9164-7
更新日期：2008-12-01 00:00:00
abstract：:Nuclear DNA contents were estimated by microdensitometry in five species of Akodon rodents: Arodon molinae, A. dolores, A. mollis, A. azarae, Bolomys obscurus) and in three chromosomal varieties of A. molinae (2n = 42; 2n = 43, 2n = 22). The data obtained showed that the species with the highest DNA content was B. obs...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02101640
更新日期：1983-01-01 00:00:00
abstract：:The mitochondrial cytochrome b (cyt-b) gene is widely used in systematic studies to resolve divergences at many taxonomic levels. The present study focuses mainly on the utility of cyt-b as a molecular marker for inferring phylogenetic relationship at various levels within the fish family Cichlidae. A total of 78 taxa...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010197
更新日期：2001-08-01 00:00:00
abstract：:Compared with the X chromosome, the mammalian Y chromosome is considerably diminished in size and has lost most of its ancestral genes during evolution. Interestingly, for the X-degenerate region on the Y chromosome, human has retained all 16 genes, while chimpanzee has lost 4 of the 16 genes since the divergence of t...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-008-9189-y
更新日期：2009-02-01 00:00:00
abstract：:The gene content of a mitochondrial (mt) genome, i.e., 37 genes and a large noncoding region (LNR), is usually conserved in Metazoa. The arrangement of these genes and the LNR is generally conserved at low taxonomic levels but varies substantially at high levels. We report here a variation in mt gene content and gene ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-005-0196-y
更新日期：2006-08-01 00:00:00
abstract：:We investigated the molecular evolution of duplicated color vision genes (LWS-1 and SWS2) within cyprinid fish, focusing on the most cavefish-rich genus--Sinocyclocheilus. Maximum likelihood-based codon substitution approaches were used to analyze the evolution of vision genes. We found that the duplicated color visio...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-009-9283-9
更新日期：2009-10-01 00:00:00
abstract：:We describe the structure of a gene expressed in the salivary gland cells of the dipteran Chironomus tentans and show that it encodes 1 of the approximately 15 secretory proteins exported by the gland cells. This sp115,140 gene consists of approximately 65 copies of a 42-bp sequence in a central uninterrupted core blo...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02101791
更新日期：1990-07-01 00:00:00
abstract：:The human Rh blood group locus consists of two structurally related genes (D and CcEe) in Rh-positive haplotypes but a single gene (CcEe) in Rh-negative haplotypes. The genome of rhesus monkeys (Macaca mulatta), while not expressing any of the human Rh D, C, c, E, or e specificities, carries a Rh-like locus strongly r...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00166163
更新日期：1994-02-01 00:00:00
abstract：:The phylogenetic relationships among Primates (human), Artiodactyla (cow), Cetacea (whale), Carnivora (seal), and Rodentia (mouse and rat) were estimated from the inferred amino acid sequences of the mitochondrial genomes using Marsupialia (opossum), Aves (chicken), and Amphibia (Xenopus) as an outgroup. The overall e...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00173421
更新日期：1994-11-01 00:00:00
abstract：:Prediction of the thermodynamic behaviors of biomolecules at high temperature and pressure is fundamental to understanding the role of hydrothermal systems in the origin and evolution of life on the primitive Earth. However, available thermodynamic dataset for amino acids, essential components for life, cannot represe...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-014-9616-1
更新日期：2014-04-01 00:00:00
abstract：:Unravelling gene structure requires the identification and understanding of the constraints that are often associated with the evolutionary history and functional domains of genes. We speculated in this manuscript with the possibility of the existence in orthologs of an emergent highly conserved gene structure that mi...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-019-09889-1
更新日期：2019-04-01 00:00:00
abstract：:Evolutionary divergence times can be inferred from molecular distances if a molecular clock can be assumed and if the substitution rate can be estimated. We present new evidence from relative rate tests that the rate of substitution at fourfold degenerate sites of nuclear genome-coding DNA is uniform in primate and ro...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00000066
更新日期：1997-01-01 00:00:00
abstract：:Molecular characteristics, especially 18S rDNA sequences, may be of great value for the study of bivalve evolution and its numerous morphological convergencies once the reliability of these data can be evaluated. The analysis of 11 published complete molluscan sequences and two new ones, Arca noae and Atrina pectinata...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02352300
更新日期：1996-07-01 00:00:00
abstract：:Explicit evaluation of the accuracy and power of maximum likelihood and Bayesian methods for detecting site-specific positive Darwinian selection presents a challenge because selective consequences of single amino acid changes are generally unknown. We exploited extensive molecular and functional characterization of a...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-008-9172-7
更新日期：2008-11-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-002-2398-x
更新日期：2003-03-01 00:00:00
abstract：:One crucial event during evolution to multicellularity was the development of either direct cell-cell contact or indirect interaction via extracellular matrix (ECM) molecules. The identification of those polypeptides provides conclusive data on the phylogenetic relationship of metazoan phyla and helps us to understand...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010230
更新日期：2001-10-01 00:00:00
abstract：:Life as we know it requires three basic types of polymers: polypeptide, polynucleotide, and polysaccharide. Here we evaluate both universal and idiosyncratic characteristics of these biopolymers. We incorporate this information into a model that explains much about their origins, selection, and early evolution. We obs...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-018-9876-2
更新日期：2018-12-01 00:00:00
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journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02101000
更新日期：1986-01-01 00:00:00
abstract：:The evolutionary speed and the consequent immune escape of H3N2 influenza A virus make it an interesting evolutionary system. Charged amino acid residues are often significant contributors to the free energy of binding for protein-protein interactions, including antibody-antigen binding and ligand-receptor binding. We...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-010-9405-4
更新日期：2011-01-01 00:00:00
abstract：:A few years ago we presented a stationary Markov model of gene evolution according to which only homologous genes from not too divergent species obeying the condition of being stationary may behave as reliable molecular clocks. A compartmentalized model of the nuclear genome in which the genes are distributed in compa...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02602910
更新日期：1989-11-01 00:00:00
abstract：:Several algae that were previously classified in the phylum Xanthophyta (yellow-green algae) were assigned in 1971 to a new phylum, Eustigmatophyta. It was anticipated that the number of algae reclassified to Eustigmatophyta would increase. However, due to the fact that the morphological characteristics that segregate...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006210
更新日期：1997-08-01 00:00:00
abstract：:Computational analysis of the hypothetical open reading frame MJ0236 from Methanococcus jannaschii reveals its membership to a family of bacterial and eukaryotic proteins, predicted to be the HMP-P kinases involved in thiamin biosyntheis (ThiD). The eukaryotic members of this family contain a C-terminal extension simi...
journal_title：Journal of molecular evolution
pub_type： 信件
doi：10.1007/pl00013145
更新日期：1997-12-01 00:00:00
abstract：:By a chromosome walking strategy the DNA region from Methanococcus vannielii flanking the genes for protein synthesis elongation factor (EF) 1 alpha and EF-2 was cloned and sequenced. A gene organization of 5' - beta' - open reading frame (ORF) 1 - ORF2 - S12 - S7 - EF-2 - EF-1 alpha - S10 - ORF3 - ORF4 - 3' was found...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02106178
更新日期：1989-07-01 00:00:00
abstract：:RNA has a myriad of biological roles in contemporary life. We use the RNA paradigm for genotype-phenotype mappings to study the evolution of multiple coding in dependence to mutation rates. We study three different one-to-many genotype-phenotype mappings which have the potential to encode the information for multiple ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-014-9648-6
更新日期：2014-12-01 00:00:00
abstract：:We have sequenced the nuclear and mitochondrial small subunit rRNA genes (rns) and the mitochondrial genes coding for subunits 1 and 3 of the cytochrome oxidase (cox1 and cox3, respectively) of the chytridiomycete Allomyces macrogynus. Phylogenetic trees inferred from the derived COX1 and COX3 proteins and the nuclear...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00175824
更新日期：1995-11-01 00:00:00
abstract：:We suggest a nucleotide substitution model that takes correlation between base-paired nucleotides into account. The model includes the estimation of the transition-transversion ratio and allows inference of the shape parameter of a discrete gamma distribution to include rate heterogeneity. A Cox-test statistic, applie...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006590
更新日期：1999-11-01 00:00:00
abstract：:The core histone genes of Saccharomyces cerevisiae are arranged as duplicate nonallelic sets of specifically paired genes. The identity of structural organization between the duplicated gene pairs would have its simplest evolutionary origin in the duplication of a complete locus in a single event. In such a case, the ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02111238
更新日期：1987-01-01 00:00:00
abstract：:Alu elements are not distributed homogeneously throughout the human genome: old elements are preferentially found in the GC-rich parts of the genome, while young Alus are more often found in the GC-poor parts of the genome. The process giving rise to this differential distribution remains poorly understood. Here we in...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-004-0020-0
更新日期：2005-03-01 00:00:00
abstract：:We describe the complete mitochondrial genome of the house centipede Scutigera coleoptrata. Its gene order is unique among characterized arthropod mitochondrial genomes. Comparison to the gene order in the horseshoe crab mtDNA implies 10 or more translocations. By extending comparisons to 30 arthropod mitochondrial ge...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-003-2563-x
更新日期：2004-04-01 00:00:00
