当前位置： SCI文献检索 > MATURITAS期刊下所有文献 > Follicle culture after ovarian cryostorage.

Follicle culture after ovarian cryostorage.

Abstract：

OBJECTIVES:Cryostorage of ovarian cortical tissue, before devastating chemo- and/or radiotherapy for cancer, permits survival of primordial and early preantral follicles. This work aims for a system allowing the long-term maturation in vitro (IVM) of small immature oocytes up to fertilisable metaphase II oocytes. METHODS:A culture system allowing follicle attachment permitted the growth and maturation of isolated follicles (follicle diameter between 100 and 130 microns) from 14-day-old (prepuberal) mice. Follicle and oocyte development were observed under the inverted microscope and conditioned medium was used for biochemical analysis. Effects of recombinant gonadotrophins and oxygen tensions were studied for their specific effects on follicle development. RESULTS:A 12-day culture period yielded full-grown oocytes which were able to complete meiosis (metaphase II). Live young were obtained after IVF and intra-uterine transfer of in vitro matured oocytes. Growth and maturation were only successful when recombinant gonadotropins were added and when the incubator had a 20% oxygen tension. This system enabled the growth of early preantral follicles after cryopreservation: 80% of frozen and thawed follicles survived up to culture-day 12 and yielded a comparable blastocyst formation rate as in controls. CONCLUSIONS:The mouse model suggests that IVM is a valuable option after oocyte storage. The development of a comparable system for long-term culture of human follicles will imply the acquisition of non-invasive techniques to appreciate oocyte's maturity and developmental capacity.

journal_name

Maturitas

journal_title

Maturitas

authors

Smitz J,Cortvrindt R

doi

10.1016/s0378-5122(98)00071-1

subject

Has Abstract

pub_date

1998-10-12 00:00:00

pages

171-9

issue

2

eissn

0378-5122

issn

1873-4111

pii

S0378-5122(98)00071-1

journal_volume

30

pub_type

杂志文章

相关文献

MATURITAS文献大全
  • Risk of onset of menopausal symptoms in periods surrounding menopause.

    abstract：OBJECTIVE:To assess the risk of onset of menopausal symptoms at different periods surrounding menopause, and variations in this risk according to age at menopause and type of menopause. METHODS:We analyzed the 27,897 women participating in the French E3N cohort study who reached menopause during a 10-year follow-up pe...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2007.09.012

    authors： Sabia S,Fournier A,Mesrine S,Boutron-Ruault MC,Clavel-Chapelon F

    更新日期：2007-12-20 00:00:00

  • Serum levels of oestrogens, progesterone, follicle-stimulating hormone and sex-hormone-binding globulin during simultaneous vaginal administration of 17 beta-oestradiol and progesterone in the pre- and post-menopause.

    abstract：:Serum concentrations of 17 beta-oestradiol (E2), unconjugated oestrone (E1), total oestrone (tE1), progesterone (P), follicle-stimulating hormone (FSH) and sex-hormone-binding globulin (SHBG) were measured before and after daily intravaginal administration of 250 micrograms micronized E2 and 10 mg micronized P for 14 ...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/0378-5122(88)90066-7

    authors： Carlström K,Pschera H,Lunell NO

    更新日期：1988-12-01 00:00:00

  • Dydrogesterone does not reverse the effects of estradiol on endothelium-dependant vasodilation in postmenopausal women: a randomised clinical trial.

    abstract：OBJECTIVES:The purpose of this study was to evaluate endothelium-dependent flow-mediated dilation (FMD) in the brachial artery and the plasma levels of endothelin-1 in postmenopausal women at risk for coronary artery disease before and after treatment with both estradiol and estradiol plus dydrogesterone. METHODS:Sixt...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0378-5122(02)00184-6

    authors： Gambacciani M,Monteleone P,Vitale C,Silvestri A,Fini M,Genazzani AR,Rosano GM

    更新日期：2002-10-25 00:00:00

  • Age-related bone loss and sarcopenia in men.

    abstract：:Bone and muscle are required for mobility but they also have endocrine and metabolic functions. In ageing as well as in many chronic diseases, bone loss and muscle atrophy occur simultaneously, leading to concomitant osteoporosis and sarcopenia. This occurs in both genders but compared with postmenopausal women, men a...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2019.01.006

    authors： Laurent MR,Dedeyne L,Dupont J,Mellaerts B,Dejaeger M,Gielen E

    更新日期：2019-04-01 00:00:00

  • The effects of postmenopausal Vitamin D treatment on vaginal atrophy.

    abstract：OBJECTIVES:To evaluate the efficacy of Vitamin D for relieving vaginal atrophy. METHODS:In our cross-sectional study, 60 eligible women were consecutively identified among patients who were followed in physical medicine and rehabilitation's outpatient clinic, during the period March June 2001. The sample consisted of ...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2004.02.008

    authors： Yildirim B,Kaleli B,Düzcan E,Topuz O

    更新日期：2004-12-10 00:00:00

  • Leptin, soluble leptin receptor, adiponectin and resistin in relation to OGTT in overweight/obese postmenopausal women.

    abstract：OBJECTIVE:In obese postmenopausal women with normal glucose metabolism (NGT) and impaired glucose tolerance (IGT) we assessed serum leptin, adiponectin, resistin, soluble leptin receptor (sOB-R) during oral glucose tolerance test (OGTT) in order to investigate their response to acute changes in glucose and insulin in t...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2008.03.012

    authors： Hroussalas G,Kassi E,Dalamaga M,Delimaris I,Zachari A,Dionyssiou-Asteriou A

    更新日期：2008-04-20 00:00:00

  • Gender differences in the incidence of and risk factors for hip fracture: A 16-year longitudinal study in a southern European population.

    abstract：OBJECTIVES:To analyze independently in men and women the incidence rate of and risk factors for hip fracture in a southern European population. Illiteracy, dementia, clinically significant depression and disability were factors to receive special emphasis. STUDY DESIGN:A community sample of 4803 individuals aged over ...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2016.12.009

    authors： Lobo E,Marcos G,Santabárbara J,Salvador-Rosés H,Lobo-Escolar L,De la Cámara C,Aso A,Lobo-Escolar A,ZARADEMP Workgroup.

    更新日期：2017-03-01 00:00:00

  • In utero exposure to carcinogens: Epigenetics, developmental disruption and consequences in later life.

    abstract：:The uterine environment is often viewed as a relatively safe haven, being guarded by the placenta which acts as a filter, permitting required materials to enter and unwanted products to be removed. However, this defensive barrier is sometimes breached by potential chemical hazards to which the mother may be subjected....

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2016.01.008

    authors： Waring RH,Harris RM,Mitchell SC

    更新日期：2016-04-01 00:00:00

  • Fatty acid and cholesterol composition of the uterine artery intima in relation to menopausal status, age, and serum cholesterol.

    abstract：OBJECTIVES:Estrogens modulate lipid metabolism and the increased risk of atherosclerosis in postmenopausal women is at least partly due to the reduction of estrogen production after menopause. We studied the effect of menopause on the contents of long-chain fatty acids, free cholesterol (FC) and cholesterol ester (CE) ...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/s0378-5122(03)00247-0

    authors： Jokela H,Salomäki A,Lehtimäki T,Teisala K,Heinonen PK,Aine R,Rontu R,Punnonen R

    更新日期：2004-02-20 00:00:00

  • Dose-dependent response of FSH, flushes and urinary calcium to oestrogen.

    abstract：:The reduction of gonadotrophin levels, urinary calcium and hot flushes in post-menopausal patients by ethinyl oestradiol is shown to be dose dependent, near maximum response being achieved by a dose of 15 micrograms daily. Equivalent ethinyl oestradiol doses to a number of other gonadal hormone preparations have been ...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/0378-5122(82)90060-3

    authors： Jones MM,Pearlman B,Marshall DH,Crilly RG,Nordin BE

    更新日期：1982-12-01 00:00:00

  • A 12-month randomized controlled trial of balance training in elderly women with osteoporosis: improvement of quality of life.

    abstract：OBJECTIVE:Physical and psychological incapacity, including fear of falling is related to decreased satisfaction with life in osteoporosis (OP). The impact of a balance exercise program on improving the quality of life is not well established. We have, therefore, investigated the effect of 12-month Balance Training Prog...

    journal_title：Maturitas

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.maturitas.2010.03.009

    authors： Madureira MM,Bonfá E,Takayama L,Pereira RM

    更新日期：2010-06-01 00:00:00

  • The values of urinary NTx in postmenopausal women undergoing HRT; the role of additional alendronate therapy.

    abstract：OBJECTIVE:To determine the changes in levels of urinary NTx at the end of the 6th month of oral and transdermal hormone replacement therapy (HRT) and the effects of additional alendronate therapy for osteoporotic women. METHOD:Of 66 postmenopausal women 23 were treated with oral estradiol+norethisterone acetate (E+P),...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/s0378-5122(02)00156-1

    authors： Posaci C,Altunyurt S,Islekel H,Saygili U,Altekin E,Onvural A,Onvural B

    更新日期：2002-08-30 00:00:00

  • Adverse skin reactions to transdermal oestradiol in tropical climate. A comparative study of skin tolerance after using oestradiol patch and gel in Thai postmenopausal women.

    abstract：:A crossover randomized comparison between two different transdermal oestradiol delivery systems has been performed in post-menopausal women of the Bangkok area. Clinical benefits were identical with the use of either a gel, applied once/day on 800 cm2 of skin and which totally evaporated within 3 min, or a patch appli...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0378-5122(91)90098-b

    authors： Sentrakul P,Chompootaweep S,Sintupak S,Tasanapradit P,Tunsaringkarn K,Dusitsin N

    更新日期：1991-06-01 00:00:00

  • Endometrial morphology after 12 months of vaginal oestriol therapy in post-menopausal women.

    abstract：:The endometrial effect of long-term vaginal oestriol (E3) therapy for urogenital atrophy was assessed in 23 post-menopausal women. Hysteroscopic and histological examinations were performed in each patient to assess endometrial atrophy before treatment and after 6 and 12 months of therapy (0.5 mg vaginal E3 for 21 day...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/0378-5122(91)90235-i

    authors： Gerbaldo D,Ferraiolo A,Croce S,Truini M,Capitanio GL

    更新日期：1991-10-01 00:00:00

  • Reprint of The Herbal Alternatives for Menopause (HALT) Study: background and study design.

    abstract：:We designed a randomized double-blind randomized trial to examine the short and long-term effects of alternative approaches commonly used to manage menopause symptoms. Women were randomly assigned to: (1) black cohosh 160 mg daily; (2) multibotanical (50 mg black cohosh, alfalfa, chaste tree, dong quai, false unicorn,...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2008.11.014

    authors： Newton KM,Reed SD,Grothaus L,Ehrlich K,Guiltinan J,Ludman E,LaCroix AZ

    更新日期：2008-09-01 00:00:00

  • Adverse drug reactions in elderly patients with cognitive disorders: A systematic review.

    abstract：:Elderly subjects with cognitive disorders are at particularly high risk of adverse drug reactions (ADRs). The objectives of our systematic review were to describe the prevalence of ADRs in elderly patients with cognitive disorders, the different types of ADRs and the medications suspected of involvement; to describe w...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2015.12.013

    authors： Kanagaratnam L,Dramé M,Trenque T,Oubaya N,Nazeyrollas P,Novella JL,Jolly D,Mahmoudi R

    更新日期：2016-03-01 00:00:00

  • Biomarkers for osteoarthritis: Can they be used for risk assessment? A systematic review.

    abstract：:The identification of early biochemical predictors of osteoarthritis (OA) has been the focus of much research over the past few years. However, it still is unclear whether current biochemical markers can be used in prognostic risk assessment of OA. The aim of this systematic review is to evaluate the possible prognost...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2015.04.004

    authors： Hosnijeh FS,Runhaar J,van Meurs JB,Bierma-Zeinstra SM

    更新日期：2015-09-01 00:00:00

  • The effects of continuous combined transdermal oestrogen-progestogen treatment on bleeding patterns and the endometrium in postmenopausal women.

    abstract：:Fifty postmenopausal women requiring hormone replacement therapy for the treatment of climacteric symptoms were recruited in six centers. All patients received a new combined norethisterone acetate (NETA)/oestradiol (E2)-TTS, (Estragest TTS, Ciba-Geigy Ltd), delivering 0.25 mg NETA and 50 micrograms E2 per day, contin...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/0378-5122(94)00891-a

    authors： Oosterbaan HP,van Buuren AH,Schram JH,van Kempen PJ,Ubachs JM,van Leusden HA,Beyer GP

    更新日期：1995-04-01 00:00:00

  • Testosterone and modifiable risk factors associated with diabetes in men.

    abstract：OBJECTIVE:The role of endogenous testosterone in the pathogenesis of type 2 diabetes mellitus remains vague. We investigated whether associations between endogenous testosterone and diabetes prevalence in men could be partially explained by modifiable risk factors. STUDY DESIGN:A random population-based cross-sectiona...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2010.12.007

    authors： Atlantis E,Lange K,Martin S,Haren MT,Taylor A,O'Loughlin PD,Marshall V,Wittert GA

    更新日期：2011-03-01 00:00:00

  • Body composition, visceral fat distribution and fat oxidation in postmenopausal women using oral or transdermal oestrogen.

    abstract：OBJECTIVES:The aim of this study was to observe hysterectomized postmenopausal women (without progestogen, which could interfere in the results), using oral-conjugated oestrogen 0.625 mg daily (n=13) or 17beta-estradiol transdermal patches delivering 50 microg daily (n=10) during 12 months, and to evaluate the treatmen...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0378-5122(03)00159-2

    authors： dos Reis CM,de Melo NR,Meirelles ES,Vezozzo DP,Halpern A

    更新日期：2003-09-25 00:00:00

  • Morphometric analysis of the urethra of castrated female rats treated with tamoxifen.

    abstract：OBJECTIVES:The aim of this study was to evaluate the effects of tamoxifen on the weight and thickness of the urethral epithelium of castrated female rats. METHODS:Forty castrated adult female Wistar-Hannover rats were randomly divided into two groups: Group I (n=20) in which the animals received only the vehicle (prop...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/j.maturitas.2008.02.010

    authors： dos Santos AR,Lopes-Costa PV,de Castro JC,Campos IC,Borges RS,Pires CG,Drumond KO,Alencar AP,da Silva BB

    更新日期：2008-03-20 00:00:00

  • Adrenocortical steroids, bone mineral content and endometrial condition in post-menopausal women.

    abstract：:In 23 post-menopausal women, serum levels of cortisol, unconjugated dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHAS), testosterone, unconjugated and total oestrone and prolactin were measured before and during an ACTH test. Significant positive correlations were found between basal levels of DHA an...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/0378-5122(82)90037-8

    authors： Brody S,Carlström K,Lagrelius A,Lunell NO,Rosenborg L

    更新日期：1982-08-01 00:00:00

  • Hormonal replacement therapy reduces forearm fracture incidence in recent postmenopausal women - results of the Danish Osteoporosis Prevention Study.

    abstract：OBJECTIVES:To study the fracture reducing potential of hormonal replacement therapy (HRT) in recent postmenopausal women in a primary preventive scenario. METHODS:Prospective controlled comprehensive cohort trial: 2016 healthy women aged 45-58 years, from three to 24 months past last menstrual bleeding were recruited ...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0378-5122(00)00158-4

    authors： Mosekilde L,Beck-Nielsen H,Sørensen OH,Nielsen SP,Charles P,Vestergaard P,Hermann AP,Gram J,Hansen TB,Abrahamsen B,Ebbesen EN,Stilgren L,Jensen LB,Brot C,Hansen B,Tofteng CL,Eiken P,Kolthoff N

    更新日期：2000-10-31 00:00:00

  • Isoflavones and cardiovascular disease.

    abstract：:The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis but a less clear protection on cardiovascular episodes, might be improved by other agonists of the estrogen receptor, such as isoflavones. By using a systematic search based on the electronic Medline database plus a hand-se...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2010.07.015

    authors： Cano A,García-Pérez MA,Tarín JJ

    更新日期：2010-11-01 00:00:00

  • The effect of tibolone on endometrial IGF-1 and IGFBP-1 levels in ovariectomized rats.

    abstract：OBJECTIVE:The goal of this study was to search the effects of two different doses of tibolone on endometrial IGF-1 and IGFBP-1 levels in ovariectomized rats. METHODS:Eighteen adult, female, 80-90-days-old, Wistar rats with an average weight of 250 g underwent bilateral ovariectomy under general anesthesia. After waiti...

    journal_title：Maturitas

    pub_type： 杂志文章

    doi：10.1016/s0378-5122(02)00068-3

    authors： Kuşcu NK,Koyuncu FM,Inan S,Tuglu I,Uyar Y,Ozbilgin K

    更新日期：2002-07-25 00:00:00

  • Combination of anabolic and antiresorptive agents for the treatment of osteoporosis.

    abstract：:Combination therapy strategies for osteoporosis are reviewed in this article. Regimens including two antiresorptives agents increase BMD more than single therapy alone, but they have not proved to reduce fracture risk. The alternative of combining antiresorptives together with anabolics has gained more interest. There...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2005.08.011

    authors： Garcés C,García LE

    更新日期：2006-04-20 00:00:00

  • Lessons to be learned from clinical studies on hormones and the breast.

    abstract：:Estrogen is a well-known mitogen in human breast epithelium but the action of progestogen is complex and incompletely understood. During the last years, accumulating data from animal, clinical and observational studies suggest a proliferative effect in breast tissue when progestogen is added to estrogen. Findings in s...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2004.06.008

    authors： Söderqvist G,von Schoultz B

    更新日期：2004-09-24 00:00:00

  • Can physical activity prevent physical and cognitive decline in postmenopausal women? A systematic review of the literature.

    abstract：BACKGROUND:Participation in regular physical activity is among the most promising and cost effective strategies to reduce physical and cognitive decline and premature death. However, confusion remains about the amount, frequency, and duration of physical activity that is likely to provide maximum benefit as well as the...

    journal_title：Maturitas

    pub_type： 杂志文章,评审

    doi：10.1016/j.maturitas.2014.06.010

    authors： Anderson D,Seib C,Rasmussen L

    更新日期：2014-09-01 00:00:00

  • Cimicifuga racemosa for the treatment of hot flushes in women surviving breast cancer.

    abstract：OBJECTIVES:To examine the effect of Cimicifuga racemosa (CR BNO 1055) on hot flushes caused by tamoxifen adjuvant therapy in young premenopausal breast cancer survivors. This treatment presents an off-label use of CR BNO 1055. METHODS:Between May 1999 and December 2001, we accrued 136 breast cancer survivors aged 35-5...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0378-5122(02)00349-3

    authors： Hernández Muñoz G,Pluchino S

    更新日期：2003-03-14 00:00:00

  • Lack of microbial proliferation and phototoxic potential of a new matrix patch for estradiol delivery.

    abstract：OBJECTIVES:To examine the potential of a new matrix system developed for estradiol delivery to cause microbial proliferation under the occluded site or to cause acute phototoxicity reactions. METHODS:Twenty healthy post-menopausal women participated in a microbial proliferation study and 11 in a phototoxicity study. B...

    journal_title：Maturitas

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0378-5122(96)01062-6

    authors： Mulberry GK,Della-Cioppa G,Monza G,Harper RA,Oelrich DM

    更新日期：1996-11-01 00:00:00