Abstract：
:In 23 post-menopausal women, serum levels of cortisol, unconjugated dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHAS), testosterone, unconjugated and total oestrone and prolactin were measured before and during an ACTH test. Significant positive correlations were found between basal levels of DHA and DHAS; DHA and unconjugated oestrone; DHA and total oestrone; testosterone and total oestrone and between unconjugated and total oestrone. ACTH significantly raised the levels of the steroids but not of prolactin. Significant positive correlations were found between basal levels and ACTH induced increments in DHA; between basal DHAS and increments in DHA and between increments in DHA and DHAS. A significant negative correlation was found between basal levels and increments in cortisol. No significant correlations were found between other combinations of hormone basal levels and/or increments. Significant positive correlations were found between basal levels of DHAS and the DHA response to ACTH respectively, and trabecular bone mineral content of the distal forearm. A significant correlation was also found between bone mineral content and pre-cancerous/cancerous state of the uterine epithelium. The results are a further support to the concept of a link between adrenal androgens and bone mineral density, and do also indicate a relation to endometrial pathology. The lack of correlation between cortisol and other steroids indicate different regulatory mechanisms. Prolactin does not seem to be involved in the regulation of the adrenal androgen synthesis.
journal_name
Maturitasjournal_title
Maturitasauthors
Brody S,Carlström K,Lagrelius A,Lunell NO,Rosenborg Ldoi
10.1016/0378-5122(82)90037-8subject
Has Abstractpub_date
1982-08-01 00:00:00pages
113-22issue
2eissn
0378-5122issn
1873-4111pii
0378-5122(82)90037-8journal_volume
4pub_type
杂志文章相关文献
MATURITAS文献大全abstract：:While the benefits of progestins in hormonal replacement therapy are well recognized as far as endometrial protection is concerned the data on breast tissue and the cardiovascular system are contentious. Following the Women's Health Initiative study, the Million Women Study and The Women's International Study of Long-...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2008.12.019
更新日期：2009-04-20 00:00:00
abstract：:Dementia is a major source of disability worldwide and there are currently no available disease-modifying treatments. Hearing loss may be associated with increased risk of dementia in later life and therefore could be a modifiable risk factor, given the availability of efficacious interventions. We investigated the as...
journal_title：Maturitas
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.maturitas.2018.03.004
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVES:Cryostorage of ovarian cortical tissue, before devastating chemo- and/or radiotherapy for cancer, permits survival of primordial and early preantral follicles. This work aims for a system allowing the long-term maturation in vitro (IVM) of small immature oocytes up to fertilisable metaphase II oocytes. METH...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(98)00071-1
更新日期：1998-10-12 00:00:00
abstract：OBJECTIVE:Physical and psychological incapacity, including fear of falling is related to decreased satisfaction with life in osteoporosis (OP). The impact of a balance exercise program on improving the quality of life is not well established. We have, therefore, investigated the effect of 12-month Balance Training Prog...
journal_title：Maturitas
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.maturitas.2010.03.009
更新日期：2010-06-01 00:00:00
abstract：:The present study had two objectives: (1) to register the prevalence of a number of climacteric complaints in a Danish general population cohort and (2) retrospectively to test the validity of an association between climacteric complaints, menopausal development, occurrence of life events and social background. A post...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(93)90043-h
更新日期：1993-11-01 00:00:00
abstract：OBJECTIVES:Levonorgestrel (LNG), delivered locally into the uterine cavity has a profound effect on the endometrium. The aim of the study was to use a LNG intrauterine system to treat non-atypical and atypical endometrial hyperplasia in women and to evaluate the long-term cure (remission) rate. METHODS:Each of the 20 ...
journal_title：Maturitas
pub_type： 临床试验,杂志文章
doi：10.1016/j.maturitas.2006.12.004
更新日期：2007-06-20 00:00:00
abstract：:In the present study, we report on an additive evaluation of mental well-being in an established program of preventive medicine including general and gynecologic examination, and screening mammography. An easy-to-use questionnaire including 19 questions was completed by 5247 women. Answers were grouped into mental wel...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(02)00010-5
更新日期：2002-04-15 00:00:00
abstract：:A crossover randomized comparison between two different transdermal oestradiol delivery systems has been performed in post-menopausal women of the Bangkok area. Clinical benefits were identical with the use of either a gel, applied once/day on 800 cm2 of skin and which totally evaporated within 3 min, or a patch appli...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0378-5122(91)90098-b
更新日期：1991-06-01 00:00:00
abstract：:Heart disease is a major cause of death, disease and disability in the developed world for both men and women. Women appear to be under-diagnosed and treated both because they fail to visit the doctor or hospital with relevant symptoms and because doctors tend to dismiss the seriousness of women's symptoms of heart di...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2009.11.019
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVES:this paper aims to report the prevalence of symptoms in the Hong Kong Chinese perimenopausal women; to construct reported symptoms into symptom groupings; and to clarify whether the symptom groups are associated with menopausal status. METHODS:a random telephone survey of perimenopausal women aged 44-55 yea...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(99)00056-0
更新日期：1999-12-15 00:00:00
abstract：:There are few prospective data on temporal trends in overall sitting time for different domains of sitting. This study examined time trends over 6 years in total and domain-specific sitting time in mid-age Australian men and women. Self-report data from 5246 participants in four survey waves (2007, 2009, 2011, 2013) o...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2018.08.006
更新日期：2018-10-01 00:00:00
abstract：:Plasma androstenedione (A) and oestrone (E1) levels were measured by radioimmunoassay in a group of 78 healthy women who had undergone a natural menopause. Of this total, 23 were symptomless (Group 1), 39 presented with a moderate climacteric syndrome (Group 2) and 16 had a severe climacteric syndrome (Group 3). The a...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(84)90017-3
更新日期：1984-04-01 00:00:00
abstract：OBJECTIVES:To develop a condition-specific quality of life (QoL) questionnaire to assess the symptoms of the decline in testosterone that occurs as men age, otherwise known as the andropause. METHODS:Two focus groups of patients with low testosterone levels and an expert panel of physicians in the treatment of male te...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(02)00274-8
更新日期：2002-12-10 00:00:00
abstract：OBJECTIVES:To design a valid and reliable questionnaire, the Malaysian Osteoporosis Knowledge Tool (MOKT), to assess the knowledge of postmenopausal osteoporotic women in Malaysia, on osteoporosis and its treatment. METHODS:A 40-item instrument was designed and tested in this study. The scores ranged from 1 to 40, whi...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2008.04.006
更新日期：2008-06-20 00:00:00
abstract：PURPOSE:The aim of this study was to investigate the putative changes in serum angiotensinase activities (aminopeptidase N, APN; aminopeptidase B, APB; aminopeptidase A, APA; aspartyl aminopeptidase, ASAP) involved in the renin-angiotensin system (RAS) in women with breast cancer treated or not with a neoadjuvant thera...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2012.02.007
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:Given the asymptomatic nature of osteoporosis, a fragility fracture provides an opportunity to make the issue of osteoporosis relevant to patients. Patients who link their fragility fracture with osteoporosis are more likely to initiate osteoporosis treatment, yet to date, we know little about who is likely t...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2013.07.014
更新日期：2013-10-01 00:00:00
abstract：:During the past 50 years, the prevalence of a cluster of chronic, inactivity-related diseases including obesity, insulin resistance and type 2 diabetes mellitus (T2DM), collectively referred to as 'metabolic syndrome' (MetS) has reached global epidemic proportions. Appropriate exercise training is a clinically proven,...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2012.05.015
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVES:Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, of BMD by using multiple regression models in a rural Chinese population. METHODS:BMDs were measured...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2006.05.001
更新日期：2007-01-20 00:00:00
abstract：:Forty-nine immigrated South-American (SA) and 48 Swedish women, aged 42-67 years, were studied in a comparative semi-structured interview survey, concerning the climacteric and its treatment. The mean age at natural menopause was 47 for the South-American women and 50 for the Swedish women. The prevalence of moderate ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(94)00855-2
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to evaluate gynecologists' knowledge of the WHI study, and its repercussions on their attitudes and practice 3 years after publication. DESIGN:A self-administered, anonymous questionnaire containing 19 questions was sent to 6000 gynecologists, members of the São Paulo Society ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2006.06.022
更新日期：2007-02-20 00:00:00
abstract：:Age-related changes in the concentrations of the main plasma electrolytes and in the urinary excretion of some of these ions have been examined in 436 pre-menopausal and 117 post-menopausal women. The main changes up to the menopause were decreases in the mean plasma potassium, calcium and total protein concentrations...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(82)90055-x
更新日期：1982-12-01 00:00:00
abstract：:Urogenital symptoms associated with estrogen loss can occur episodically throughout a woman's life (e.g. during lactation, during treatment with GnRH agonists, etc.) but it is most common and chronic in duration in postmenopausal women. More than 50% of postmenopausal women experience lack of vaginal lubrication and f...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(95)00956-6
更新日期：1995-12-01 00:00:00
abstract：OBJECTIVES:To characterise changes in nationwide fall-related mortality rates in Australia and the United Kingdom (UK) between 2006 and 2016 by age group and sex. STUDY DESIGN:Trend analysis of falls mortality data from World Health Organization (WHO) Mortality Database for the Australian and UK population. MAIN OUTC...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2020.07.008
更新日期：2020-12-01 00:00:00
abstract：:The mean plasma anion gap (Na + K + Ca + Mg)--(Cl + HCO3(-) + HPO4(2-) + protein), was significantly higher in post-menopausal women compared with pre-menopausal women (8.04 mEq/l compared with 7.03 mEq/l). This change was due, in part, to an increase in the plasma lactate concentration and to smaller increases in cit...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(84)90049-5
更新日期：1984-03-01 00:00:00
abstract：:Beneficial effects on health of limiting food intake for certain periods of time have been recognized for a long time. While many diets can produce short-term weight loss, most fail to result in a long-lasting impact. Current data suggest that intermittent fasting may be beneficial for overall health and wellbeing. Ho...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2014.08.007
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To describe the prevalence of hormone replacement therapy (HT) use by postmenopausal women doctors and doctors' wives in Italy and to explore the relationship between their personal characteristics and HT use. DESIGN:A total of 500 women doctors and 500 men doctors answering on behalf of their female partner...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2005.10.008
更新日期：2006-05-20 00:00:00
abstract：INTRODUCTION:This review examines whether functional and cognitive decline and mortality after an episode of delirium are comparable between patients with and those without dementia. METHODS:MEDLINE and EMBASE were searched systematically for 'dementia' and 'delirium'. After screening of the results, studies were rate...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2019.03.005
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVES:There is evidence that menopausal symptoms manifested at peri-menopause occur less frequently when compared to the symptoms experienced at post-menopause. The aim of this study was to investigate this and to test the hypothesis that depressive symptomatology mediates the relationship between menopausal stage...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2015.03.007
更新日期：2015-06-01 00:00:00
abstract：UNLABELLED:Social engagement provides dynamic stimulation for older individuals that influences cognition. Grandparenting is an increasingly popular form of childcare that provides social activity for older adults. OBJECTIVE:To investigate the relationship between grandparenting, as a form of social engagement, and co...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2015.03.013
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Physical multimorbidity, defined as the presence of two or more chronic physical conditions, is widespread and reduces life expectancy and quality of life in older adults. Sedentary behavior (SB) is increasingly identified as a risk factor for a range of chronic physical conditions, independent of physical a...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2020.01.007
更新日期：2020-04-01 00:00:00
