Specific-antibody-secreting cells in the rectums and genital tracts of nonhuman primates following vaccination.

abstract：:Cell-mediated immunity is critical in host resistance against the pathogenic fungus Histoplasma capsulatum. To explore the role of L3T4+ T cells in protection of mice against H. capsulatum infection, we examined the effect of in vivo treatment with anti-L3T4 monoclonal antibody (MAb) GK1.5 on the course of murine diss...

journal_title：Infection and immunity

authors： Gomez AM,Bullock WE,Taylor CL,Deepe GS Jr

更新日期：1988-07-01 00:00:00

abstract：:A toxin associated with Toxoplasma gondii infection was obtained from the trophozoites and culture medium used to propagate the parasite in cell cultures. The toxin, named Toxofactor (TF), administered parenterally or nonparenterally in adult mice, produces transient symptoms of lethargy, ruffled fur, and body weight ...

journal_title：Infection and immunity

authors： Grimwood B,O'Connor G,Gaafar HA

更新日期：1983-12-01 00:00:00

abstract：:In a mouse model of thermal injury, an increase in burn size produced a decrease in the ratio of Candida albicans cells adherent to the marginal zone to those adherent to the white pulp of the spleen, an increase in the number of Candida cells in the circulation and in the kidneys, and an increase in mortality. ...

journal_title：Infection and immunity

authors： Neely AN,Orloff MM,Holder IA,Healy DP

更新日期：1997-08-01 00:00:00

abstract：:In a previous study we showed that the involvement of EP4 subtype of the prostaglandin E (PGE) receptor is crucial for lipopolysaccharide (LPS)-induced osteoclast formation in vitro. The present study was undertaken to test whether EP4 is actually associated with LPS-induced bone resorption in vivo. In wild-type (WT) ...

journal_title：Infection and immunity

authors： Sakuma Y,Tanaka K,Suda M,Komatsu Y,Yasoda A,Miura M,Ozasa A,Narumiya S,Sugimoto Y,Ichikawa A,Ushikubi F,Nakao K

更新日期：2000-12-01 00:00:00

abstract：:Type 1 fimbrial phase-locked mutants of uropathogenic Escherichia coli cystitis isolate F11 were used to assess the role of the invertible element during urinary tract infection. Compared to the wild type, the phase-locked off mutant was attenuated, and constitutive production of type 1 fimbriae by the phase-locked on...

journal_title：Infection and immunity

authors： Snyder JA,Lloyd AL,Lockatell CV,Johnson DE,Mobley HL

更新日期：2006-02-01 00:00:00

abstract：:The development of chronic pathology in mice at 2 to 10 months after inoculation of 10(2) T. cruzi trypomastigotes can be prevented by preimmunization with live, attenuated culture parasites (strain TCC). Swiss mice received one or three immunizing inoculations of 10(6) TCC organisms and were challenged with 10(2) Tul...

journal_title：Infection and immunity

authors： Basombrío MA,Besuschio S

更新日期：1982-04-01 00:00:00

abstract：:As part of a study of virulence gene regulation in Streptococcus pneumoniae, we have identified a gene encoding a homologue of the staphylococcal catabolite control protein CcpA in the pneumococcal genome sequence. The pneumococcal protein, designated RegM, has significant similarity to members of the LacI/GalR family...

journal_title：Infection and immunity

authors： Giammarinaro P,Paton JC

更新日期：2002-10-01 00:00:00

abstract：:Lewis (Le) antigens have been implicated in the pathogenesis of atrophic gastritis and gastric cancer in the setting of Helicobacter pylori infection, and H. pylori-induced anti-Le antibodies have been described that cross-react with the gastric mucosa of both mice and humans. The aim of this study was to examine the ...

journal_title：Infection and immunity

authors： Heneghan MA,McCarthy CF,Janulaityte D,Moran AP

更新日期：2001-08-01 00:00:00

abstract：:Peptic ulcer disease (PUD) occurs after a long-term Helicobacter pylori infection. However, the disease can develop earlier, and rare cases have been observed in children, suggesting that these H. pylori strains may be more virulent. We used suppressive subtractive hybridization for comparative genomics between H. pyl...

journal_title：Infection and immunity

authors： Oleastro M,Monteiro L,Lehours P,Mégraud F,Ménard A

更新日期：2006-07-01 00:00:00

abstract：:The recent finding that high numbers of strict anaerobes are present in the respiratory tract of cystic fibrosis (CF) patients has drawn attention to the pathogenic contribution of the CF microbiome to airway disease. In this study, we investigated the specific interactions of the most dominant bacterial CF pathogen, ...

journal_title：Infection and immunity

authors： Pustelny C,Komor U,Pawar V,Lorenz A,Bielecka A,Moter A,Gocht B,Eckweiler D,Müsken M,Grothe C,Lünsdorf H,Weiss S,Häussler S

更新日期：2015-01-01 00:00:00

abstract：:Gram-negative bacterial cells exposed to a complement source may carry membrane attack complexes containing variable numbers of C9 molecules per C5b-8 site. In order to investigate the assembly of this complex, the ability of C9 molecules to bind to C5b-8 complexes was compared with the binding characteristics of C9 f...

journal_title：Infection and immunity

authors： MacKay SL,Dankert JR

更新日期：1994-07-01 00:00:00

abstract：:The effect of route of administration, dosage, and number of boosts employed during immunization with the polymyxin-release form of Escherichia coli heat-labile (LT) enterotoxin on the degree and duration of protection afforded was evaluated in rats which were challenged by the ligated loop technique. Increasing the b...

journal_title：Infection and immunity

authors： Klipstein FA,Engert RF

更新日期：1980-01-01 00:00:00

abstract：:Arthritis is a frequent and major complication of infection with Borrelia burgdorferi sensu stricto. The antigens responsible for the induction of arthritis are unknown. Here we provide direct evidence that a major surface protein, outer surface protein A (OspA), can induce arthritis. Hamsters were vaccinated with 30,...

journal_title：Infection and immunity

authors： Croke CL,Munson EL,Lovrich SD,Christopherson JA,Remington MC,England DM,Callister SM,Schell RF

更新日期：2000-02-01 00:00:00

abstract：:Both idiopathic and infectious forms of colitis disrupt normal intestinal epithelial cell (IEC) proliferation and differentiation, although the mechanisms involved remain unclear. Recently, we demonstrated that infection by the attaching and effacing murine pathogen Citrobacter rodentium leads to a significant reducti...

journal_title：Infection and immunity

authors： Chan JM,Bhinder G,Sham HP,Ryz N,Huang T,Bergstrom KS,Vallance BA

更新日期：2013-12-01 00:00:00

abstract：:We studied the oligosaccharides (OS) of outer membrane lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis. OS from the LOS of an individual neisserial strain always eluted from Sephadex G-50S as multiple peaks; the polyacrylamide gel elution profiles were nearly identical to the polyacrylam...

journal_title：Infection and immunity

authors： Griffiss JM,O'Brien JP,Yamasaki R,Williams GD,Rice PA,Schneider H

更新日期：1987-08-01 00:00:00

abstract：:In meningococcal septic shock, the dominant inducer of inflammation is lipopolysaccharide (LPS) in the outer membrane of Neisseria meningitidis, while interleukin-10 (IL-10) is the principal anti-inflammatory cytokine. We have used microarrays and Ingenuity Pathway Analysis to study the global effects of IL-10 on gene...

journal_title：Infection and immunity

authors： Gopinathan U,Ovstebø R,Olstad OK,Brusletto B,Dalsbotten Aass HC,Kierulf P,Brandtzaeg P,Berg JP

更新日期：2012-11-01 00:00:00

abstract：:To analyze the role of interleukin-10 (IL-10) in bacterial cerebral infections, we studied cerebral listeriosis in IL-10-deficient (IL-10(-/-)) and wild-type (WT) mice, the latter of which express high levels of IL-10 in both primary and secondary cerebral listeriosis. IL-10(-/-) mice succumbed to primary as well as s...

journal_title：Infection and immunity

authors： Deckert M,Soltek S,Geginat G,Lütjen S,Montesinos-Rongen M,Hof H,Schlüter D

更新日期：2001-07-01 00:00:00

abstract：:The ability of intracellular pathogens to sense and adapt to the hostile environment of the host is an important factor governing virulence. We have sequenced the operon encoding the major heat shock proteins GroES and GroEL in the gram-positive food-borne pathogen Listeria monocytogenes. The operon has a conserved or...

journal_title：Infection and immunity

authors： Gahan CG,O'Mahony J,Hill C

更新日期：2001-06-01 00:00:00

abstract：:Mice were vaccinated with plasmid DNA (pDNA) encoding antigen 85A (Ag85A), Ag85B, or PstS-3 from Mycobacterium tuberculosis either in saline or formulated for intramuscular injections in VC1052:DPyPE (aminopropyl-dimethyl-myristoleyloxy-propanaminium bromide-diphytanoylphosphatidyl-ethanolamine) (Vaxfectin; Vical, Inc...

journal_title：Infection and immunity

authors： D'Souza S,Rosseels V,Denis O,Tanghe A,De Smet N,Jurion F,Palfliet K,Castiglioni N,Vanonckelen A,Wheeler C,Huygen K

更新日期：2002-07-01 00:00:00

abstract：:We have determined the nucleotide sequence of the 1.4-kilobase DNA fragment containing the plasminogen activator gene (pla) of Yersinia pestis, which determines both plasminogen activator and coagulase activities of the species. The sequence revealed the presence of a 936-base-pair open reading frame that constitutes ...

journal_title：Infection and immunity

authors： Sodeinde OA,Goguen JD

更新日期：1989-05-01 00:00:00

abstract：:A zone of extracellular digestion of the mucin layer around Candida albicans blastoconidia was observed by transmission electron microscopy in the jejunum of mice inoculated intragastrically (G. T. Cole, K. R. Seshan, L. M. Pope, and R. J. Yancey, J. Med. Vet. Mycol. 26:173-185, 1988). This observation prompted the hy...

journal_title：Infection and immunity

authors： Colina AR,Aumont F,Deslauriers N,Belhumeur P,de Repentigny L

更新日期：1996-11-01 00:00:00

abstract：:Chromosomal DNA from a uropathogenic strain of Escherichia coli was partially digested with the restriction enzyme EcoRI. The partial digests were ligated into a cosmid containing an ampicillin-resistant determinant and packaged into lambda phage particles. An ampicillin-resistant transductant of E. coli HB101 was fou...

journal_title：Infection and immunity

authors： Clegg S

更新日期：1982-11-01 00:00:00

abstract：:Sendai virus hemagglutinin-neuraminidase (HN) and fusion (F) glycoproteins, F and HN, were separated from Triton X-100- or Nonidet P-40-solubilized envelopes as unadsorbed and eluted fractions, respectively, by using glutaralde-hyde-treated chicken erythrocytes. These separated glycoproteins were biologically active. ...

journal_title：Infection and immunity

authors： Hosaka Y

更新日期：1980-10-01 00:00:00

abstract：:Gram-negative organisms incorporate hydroxy fatty acids into the lipid A moiety of lipopolysaccharide (LPS), and in the case of some members of the family Enterobacteriaceae, hydroxy fatty acids are incorporated exclusively into lipid A. However, a limited number of Bacteroides species have been shown to incorporate s...

journal_title：Infection and immunity

authors： Nichols FC

更新日期：1994-09-01 00:00:00

abstract：:The relationship between hypersensitivity and cellular resistance to infection with facultative intracellular parasites was studied in mice by using infection-immunity in tularemia as a model system. Delayed hypersensitivity to antigenic fractions of Francisella tularensis was first detected 6 to 7 days after immuniza...

journal_title：Infection and immunity

authors： Claflin JL,Larson CL

更新日期：1972-03-01 00:00:00

abstract：:Pyolysin (PLO), a cholesterol-dependent cytolysin expressed by Arcanobacterium pyogenes, is an important host-protective antigen. However, this molecule is toxic and requires inactivation prior to its use as a vaccine. Three genetically toxoided, nonhemolytic PLO molecules, HIS-PLO.F(497), HIS-PLO.Delta P(499), and HI...

journal_title：Infection and immunity

authors： Jost BH,Trinh HT,Songer JG,Billington SJ

更新日期：2003-05-01 00:00:00

abstract：:While gamma/delta T cells are involved in host defense and immunopathology in a variety of infectious diseases, their precise role is not yet clearly defined. In the absence of gamma/delta T cells, mice die after infection with a dose of Listeria monocytogenes that is not lethal in immunologically intact animals. Morb...

journal_title：Infection and immunity

authors： Skeen MJ,Rix EP,Freeman MM,Ziegler HK

更新日期：2001-12-01 00:00:00

abstract：:We have previously demonstrated the existence of Klebsiella pneumoniae clinical isolates deficient in the lipopolysaccharide O side chain, the major factor for resistance to complement-mediated killing in this bacterial species. These isolates are complement resistant, and their mechanisms to resist complement were in...

journal_title：Infection and immunity

authors： Alvarez D,Merino S,Tomás JM,Benedí VJ,Albertí S

更新日期：2000-02-01 00:00:00

abstract：:During persistence of nonencapsulated Haemophilus influenzae in the respiratory tracts of patients with chronic bronchitis, the major outer membrane proteins (MOMPs) P2 and P5 show antigenic drift. The hypothesis that appearance of antigenic variants is the consequence of antibody-dependent selection was tested in a r...

journal_title：Infection and immunity

authors： Vogel L,Duim B,Geluk F,Eijk P,Jansen H,Dankert J,vanAlphen L

更新日期：1996-03-01 00:00:00

abstract：:Potassium thiocyanate extracts of a virulent Pasteurella multocida 3:A rabbit isolate were prepared and used as a vaccine in rabbits. The extract contained protein, carbohydrate, hyaluronic acid, lipopolysaccharide, DNA, and RNA. The protein and lipopolysaccharide profiles of the extract were similar to those of the P...

journal_title：Infection and immunity

authors： Lu YS,Pakes SP,Massey L,Stefanu C

更新日期：1987-12-01 00:00:00