Abstract:
:After more than two centuries of almost sporadic inquiry as to the existence and function of the human vomeronasal system (VNS), the last decade has seen a resurgent interest in it. The principal question vexing many laboratories is whether adult humans retain the VNS that clearly develops during fetal growth. Additional questions are whether the structurally defined fetal VNS has any function role, and if this structure and function extend into postnatal life. One research tool that has been successfully used to identify key components of the mammalian VNS has been immunohistochemistry (IHC). This technique has clearly defined the vomeronasal receptor neurons in the vomeronasal organ, the vomeronasal nerve that projects into the central nervous system, and the target of this nerve, the accessory olfactory bulb. This review will discuss immunohistochemical studies that have identified these features in the mammalian VNS, and relate them to structural and IHC studies of the fetal and adult human VNS. Suggestions as to future studies to clarify the status of the human VNO also are offered.
journal_name
Microsc Res Techjournal_title
Microscopy research and techniqueauthors
Johnson EWdoi
10.1002/(SICI)1097-0029(19980615)41:6<530::AID-JEMsubject
Has Abstractpub_date
1998-06-15 00:00:00pages
530-41issue
6eissn
1059-910Xissn
1097-0029pii
10.1002/(SICI)1097-0029(19980615)41:6<530::AID-JEMjournal_volume
41pub_type
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