Comparative B-mode and Doppler renal ultrasonography with histopathological findings in dogs positive for canine visceral leishmaniasis.

Abstract:

:Morphological parameters and renal flow were assessed and measured in six clinically healthy dogs with negative serological and parasitological examinations for canine visceral leishmaniasis (CVL) and six dogs with CVL-positive serological and parasitological tests and asymptomatic condition of the disease. Kidney length and diameter were measured and compared with the aorta/kidney ratio. Alterations in flow were measured using the flow velocity (cm/s) and resistance index (RI). Renal function was assessed by serum biochemical examination (urea, creatine, total proteins, albumin, and globulin) and urinalysis. CVL-positive animals presented heterogeneous kidney echotexture, reduced vascular flow, hypoperfusion, lesser visualization of the arcuate arteries, high RI values (1.06 ± 0.28 for the right kidney and 1.10 ± 0.30 for the left kidney), reduced diastolic flow, and high systolic peak. They also presented positive creatine/RI correlation and between the renal artery vascular flow and kidney diameter. Histopathological analysis of CVL-positive animals was compatible and confirmed hemodynamic changes observed by Doppler ultrasound. The findings in the present study showed that Doppler ultrasonography is a valid method to assess and detect alterations in flow in renal pathological processes with kidney vascular damage, as in the case of leishmaniasis, and can help in the diagnosis of animals with this infection. Microsc. Res. Tech. 79:637-645, 2016. © 2016 Wiley Periodicals, Inc.

journal_name

Microsc Res Tech

authors

Baltazar PI,Da Silva Moura L,Pessoa GT,De Sá Rodrigues RP,Sanches MP,Das Neves Diniz A,Das Chagas Araújo Sousa F,Guerra PC,Neves WC,Giglio RF,De Jesus Rosa Pereira Alves J,De Assis Leite Souza F,Braga JF,Alves FR

doi

10.1002/jemt.22677

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

637-45

issue

7

eissn

1059-910X

issn

1097-0029

journal_volume

79

pub_type

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