The depression system: preliminary studies.

Abstract:

:The learned helplessness paradigm was used to test the notion that lesions of a theatrical depression system in the rat will produce antidepression similar to antidepressive medication. Lateral brain stem lesions were effective in producing antidepression and unilateral lesions were as effective as bilateral lesions. Ibotenic acid lesions were not effective, indicating that the effective target site was in a fiber tract and not a cell nucleus.

authors

Richardson DE,Dempsey CW,Song JH

doi

10.1159/000099928

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

221-5

issue

1-4 Pt 1

eissn

1011-6125

issn

1423-0372

journal_volume

68

pub_type

杂志文章
  • Bilateral subthalamic deep brain stimulation for camptocormia associated with Parkinson's disease.

    abstract:BACKGROUND:Few multiple case studies of the effects of deep brain stimulation for camptocormia associated with Parkinson's disease have been reported. Although deep brain stimulation was in some cases not effective against camptocormia, it is unclear in which types of patients it was effective in treating camptocormia....

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000324907

    authors: Asahi T,Taguchi Y,Hayashi N,Hamada H,Dougu N,Takashima S,Tanaka K,Endo S

    更新日期:2011-01-01 00:00:00

  • Gamma knife radiosurgery for growth hormone-secreting pituitary adenomas invading the cavernous sinus.

    abstract::The authors assessed whether gamma knife radiosurgery is effective for patients with acromegaly where the pituitary tumors invaded the cavernous sinus. Radiosurgery was performed on 9 patients (average of 20 Gy to the tumor margin), 8 of whom had already undergone transsphenoidal surgery and/or craniotomy with occasio...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000066721

    authors: Fukuoka S,Ito T,Takanashi M,Hojo A,Nakamura H

    更新日期:2001-01-01 00:00:00

  • Intraoperative cortical mapping has low sensitivity for the detection of motor function in proximity to a tumor in the primary motor area.

    abstract::Six patients with brain tumors within or near the primary motor cortex underwent preoperative functional magnetic resonance imaging (fMRI) and intraoperative cortical mapping, and the accuracy of those techniques for localization of the primary motor cortex and motor function beside the tumor were determined by compar...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000088160

    authors: Shinoura N,Yamada R,Kodama T,Suzuki Y,Takahashi M,Yagi K

    更新日期:2005-01-01 00:00:00

  • Black holes, white dwarfs and supernovas: imaging after radiosurgery.

    abstract:PURPOSE:To evaluate the imaging and pathological correlates of successful or risk-related stereotactic radiosurgery (SR). Methods and Materials. The ten-year Gamma Knife experience in 2,344 patients at the University of Pittsburgh was reviewed. In addition, the results or radiosurgery primate, rat, and mouse models wer...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000056401

    authors: Lunsford LD,Kondziolka D,Maitz A,Flickinger JC

    更新日期:1998-10-01 00:00:00

  • Acoustic neurinomas with macrocysts treated with Gamma Knife radiosurgery.

    abstract::Six cases of acoustic neurinomas with macrocystic components are presented. In three cases the cystic portion was within the tumor, while in the other three, the cyst was peritumoral, in the form of a cul-de-sac within the arachnoid, in other words it was not a true tumor cyst. The six tumors are from a series of 74 a...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000099775

    authors: Pendl G,Ganz JC,Kitz K,Eustacchio S

    更新日期:1996-01-01 00:00:00

  • Thalamotomy and caudatotomy with the Gamma Knife as a treatment for parkinsonism with a comment on lesion sizes.

    abstract::Radiosurgery with the Gamma Knife was performed in 12 patients with parkinsonism. In 9 patients small lesions were created in the head of the caudate nucleus bilaterally. Two patients underwent radiosurgical thalamotomy, and 1 patient was treated with caudatotomy and thalamotomy. After a follow-up period of 1-12 month...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000098781

    authors: Friehs GM,Ojakangas CL,Pachatz P,Schröttner O,Ott E,Pendl G

    更新日期:1995-01-01 00:00:00

  • Longevity of batteries in internal pulse generators used for deep brain stimulation.

    abstract::The longevity of batteries in internal pulse generators (IPGs) used clinically for deep brain stimulation is not known. We conducted a study to assess the life span of these batteries. From 1993 to 2000, 163 single-channel batteries were surgically implanted in our institution. The electrical settings utilized in pati...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000075161

    authors: Bin-Mahfoodh M,Hamani C,Sime E,Lozano AM

    更新日期:2003-01-01 00:00:00

  • Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.

    abstract:BACKGROUND:In nonresectable glioblastoma (GBM), stereotactic biopsies are performed to retrieve tissue for diagnostic purposes. The analysis of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation adds prognostic and predictive information. OBJECTIVES:The aim of the study was to detect confounding factor...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000360582

    authors: Weise LM,Harter PN,Eibach S,Braczynski AK,Dunst M,Rieger J,Bähr O,Hattingen E,Steinbach JP,Plate KH,Seifert V,Mittelbronn M

    更新日期:2014-01-01 00:00:00

  • Gamma Knife Radiosurgery of Brainstem Cavernous Malformations.

    abstract:BACKGROUND/AIMS:Our study aimed to evaluate the efficiency and morbidity of Gamma Knife radiosurgery (GKS) in the treatment of hemorrhagic brainstem cavernous malformations (CMs). METHODS:We included in this study all patients who underwent GKS for the treatment of a hemorrhagic brainstem CM(s) in our institution betw...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000452844

    authors: Aboukais R,Estrade L,Devos P,Blond S,Lejeune JP,Reyns N

    更新日期:2016-01-01 00:00:00

  • A system for microscope-assisted guided interventions.

    abstract::We present a system for surgical navigation using stereo overlays in the operating microscope aligned to the operative scene. This augmented reality system provides 3D information about nearby structures and offers a significant advancement over pointer-based guidance, which provides only the location of one point and...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000029708

    authors: King AP,Edwards PJ,Maurer CR Jr,de Cunha DA,Hawkes DJ,Hill DL,Gaston RP,Fenlon MR,Strong AJ,Chandler CL,Richards A,Gleeson MJ

    更新日期:1999-01-01 00:00:00

  • Gamma Knife radiosurgery in cerebral arteriovenous malformations: postobliteration nidus changes observed on neurodiagnostic imaging.

    abstract::Computed tomographic (CT), magnetic resonance (MR), MR angiographic and angiographic images, obtained after complete nidus obliteration had been angiographically confirmed, were reviewed in 9 patients who had undergone Gamma Knife treatment for cerebral arteriovenous malformations (AVMs). The period between angiograph...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000098772

    authors: Yamamoto M,Jimbo M,Ide M,Lindquist C,Steiner L

    更新日期:1995-01-01 00:00:00

  • Bilateral cingulotomy and anterior capsulotomy applied to patients with aggressiveness.

    abstract:OBJECTIVE:To perform a preliminary study on the effects and safety of bilateral cingulotomy and anterior capsulotomy in patients with aggressive behavior. PATIENTS AND METHODS:Twenty-three psychiatric patients showing aggressive behavior refractory to conventional treatment were initially evaluated. The subjects were ...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000336746

    authors: Jiménez F,Soto JE,Velasco F,Andrade P,Bustamante JJ,Gómez P,Ramírez Y,Carrillo-Ruiz JD

    更新日期:2012-01-01 00:00:00

  • Transplantation of adrenal medullary tissue to caudate nucleus using stereotactic techniques.

    abstract::Stereotactic techniques were used to transplant adrenal medullary tissue to the head of the right caudate nucleus in 12 patients with Parkinson's disease. No significant lasting complications were seen. All patients had an initial improvement. 11 of the 12 patients remain improved over their preoperative condition aft...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000100221

    authors: Gildenberg PL,Pettigrew LC,Merrell R,Butler I,Conklin R,Katz J,DeFrance J

    更新日期:1990-01-01 00:00:00

  • Fractionated stereotactic radiotherapy for intracranial neoplasms.

    abstract::Fractionated stereotactic radiotherapy is a method which attempts to combine the radiobiological advantages offered by dose fractionation with a technique for focal delivery of radiation. At McGill University, fractionated stereotactic radiotherapy is given with a linear accelerator-based dynamic stereotactic radiosur...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000098941

    authors: Olivier A,Sadikot AF,Villemure JG,Pokrupa R,Souhami L,Podgorsak EB,Hazel J

    更新日期:1992-01-01 00:00:00

  • Radiosurgical treatment of meningiomas.

    abstract::From January 1992 to November 1996, 17 patients with the diagnosis of intracranial meningioma underwent radiosurgical treatment. Of these, 7 patients were treated using a Linac-based system (group 1), and 10 using the Leksell Gamma Knife unit (group 2). The follow-up ranged between 12 and 48 (median 33) months for gro...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000099869

    authors: Zamorano L,Saenz A,Matter A,Buciuc R,Gaspar L,Fontanesi J,Garzon A,Diaz F

    更新日期:1997-01-01 00:00:00

  • Nonvolumetric stereotaxy-assisted craniotomy. Results in 50 consecutive cases.

    abstract::Craniotomy using stereotactic techniques has the potential to improve the extent of tumor resection and to reduce wound and neurologic morbidity. Most reports of stereotaxy-assisted craniotomy (SC) for tumor resection have focused on techniques using sophisticated computer hardware and volumetric software. Results of ...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1159/000100625

    authors: Barnett GH,McKenzie RL,Ramos L,Palmer J

    更新日期:1993-01-01 00:00:00

  • Acute and Subacute Presentations of Cerebral Edema following Deep Brain Stimulation Lead Implantation.

    abstract:BACKGROUND/AIMS:Postoperative cerebral edema around a deep brain stimulation (DBS) electrode is an uncommon reported complication. The goal of this study was to identify instances of postoperative edema based on clinical presentation, and to remark on their management. METHODS:A retrospective chart review was performe...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000454892

    authors: Fenoy AJ,Villarreal SJ,Schiess MC

    更新日期:2017-01-01 00:00:00

  • Pedunculopontine nucleus deep brain stimulation in a patient with primary progressive freezing gait disorder.

    abstract:BACKGROUND:Pedunculopontine nucleus (PPN) deep brain stimulation (DBS) has recently been suggested for treatment of medication-unresponsive gait and axial symptoms in Parkinson's disease. Patients with the rare primary progressive freezing gait disorder (PPFG) have similar disabling symptoms and few therapeutic options...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000268742

    authors: Ostrem JL,Christine CW,Glass GA,Schrock LE,Starr PA

    更新日期:2010-01-01 00:00:00

  • Electrical Stimulation of Subiculum for the Treatment of Refractory Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis: A 2-Year Follow-Up Study.

    abstract:INTRODUCTION:Evidence has been provided that the subiculum may play an important role in the generation of seizures. Electrical stimulation at this target has been reported to have anticonvulsive effects in kindling and pilocarpine rat models, while in a clinical study of hippocampal deep brain stimulation (DBS), conta...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000510295

    authors: Vázquez-Barrón D,Cuéllar-Herrera M,Velasco F,Velasco AL

    更新日期:2020-10-28 00:00:00

  • Combining brain diagnosis and therapy in a single strategy: the safety, reliability, and cost implications using same-day versus separate-day stereotactic procedures.

    abstract:BACKGROUND:A therapeutic radiosurgery procedure usually follows a separate diagnostic stereotactic procedure after days or weeks. OBJECTIVES:To define the clinical reliability, safety, and cost implications of same-day diagnostic stereotactic biopsy and therapeutic radiosurgery. METHODS:During an 8-year interval, 26 ...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000332057

    authors: Park KJ,Niranjan A,Kondziolka D,Kano H,Castillo P,Matchett JC,Flickinger JC,Lunsford LD

    更新日期:2011-01-01 00:00:00

  • Plasticity in human somatosensory thalamus as a result of deafferentation.

    abstract::Experimental studies indicate that deafferentation results in reorganization of the somatosensory map at various levels of the CNS, such that the representation of a body part adjacent to a region that is denervated expands into the deafferented area. Recent data suggest that in the human this occurs at the cortical l...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000098612

    authors: Kiss ZH,Dostrovsky JO,Tasker RR

    更新日期:1994-01-01 00:00:00

  • Combined Unilateral Posteroventral Pallidotomy and Ventral Intermediate Nucleus Thalamotomy in Tremor-Dominant Parkinson's Disease versus Posteroventral Pallidotomy Alone: A Prospective Comparative Study.

    abstract:BACKGROUND:The optimum target in surgery for Parkinson's disease (PD) is still controversial, especially in patients with tremor-dominant PD. We aim to compare results in tremor-dominant patients undergoing pallidotomy vs. those undergoing simultaneous posteroventral pallidotomy (PVP) and ventral intermediate nucleus (...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000492229

    authors: Fayed ZY,Radwan H,Aziz M,Eid M,Mansour AH,Nosseir M,Anwer H,Elserry T,Abdel Ghany WA

    更新日期:2018-01-01 00:00:00

  • Historic evolution of open cingulectomy and stereotactic cingulotomy in the management of medically intractable psychiatric disorders, pain and drug addiction.

    abstract::Stereotactic cingulotomy constitutes a psychosurgical procedure nowadays advocated in the treatment of medically intractable obsessive-compulsive disorder, chronic pain and drug addiction. From its theoretical conception to the first cingulectomies performed and modern stereotactic-guided cingulotomies, various target...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000226669

    authors: Brotis AG,Kapsalaki EZ,Paterakis K,Smith JR,Fountas KN

    更新日期:2009-01-01 00:00:00

  • Computer-aided/image-guided and video-endoscopic resection of pituitary tumors.

    abstract::Endoscopic pituitary surgery is a minimally invasive method which allows simple transnasal transphenoidal surgical access without retractors, and has been used by our team in 536 patients from 1993 to 1999. In 326 of these patients, computer-aided image-guided techniques (CAN) were used in conjunction with endoscopy. ...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000056481

    authors: Pillay PK,Leo CW,Sethi DS

    更新日期:2000-01-01 00:00:00

  • Stereotactic gamma radiosurgery for intracranial vascular malformations and tumors: report of the initial North American experience in 331 patients.

    abstract::We reviewed the initial experience with 331 consecutive patients treated during the first 2 years of operation of the University of Pittsburgh Gamma Unit. Among 178 patients with vascular malformations, 161 had angiographically demonstrable arteriovenous malformations, and 17 had angiographically occult malformations....

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000100269

    authors: Coffey RJ,Lunsford LD,Bissonette D,Flickinger JC

    更新日期:1990-01-01 00:00:00

  • Analysis of parameters for epidural spinal cord stimulation. 3. Topographical distribution of paresthesiae--a preliminary analysis of 266 combinations with contacts implanted in the midcervical and midthoracic vertebral levels.

    abstract::As a part of the systematic analysis of parameters involved in electrical epidural spinal cord stimulation therapy, distribution of paresthesiae in accordance with the position of contacts, as related to midline and vertebral level of contacts, was investigated. A preliminary analysis performed for 266 combinations ha...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000100632

    authors: Tulgar M,He J,Barolat G,Ketcik B,Struijk H,Holsheimer J

    更新日期:1993-01-01 00:00:00

  • Bilateral anterior capsulotomy for refractory obsessive-compulsive disorders.

    abstract::A prospective study on the effects of bilateral anterior capsulotomy in patients with refractory obsessive-compulsive disorder (OCD) is presented. A total of 18 procedures were performed in 15 patients. The mean duration of the OCDs was 18.1 +/- 5.6 years (range 11-26 years). The mean total Yale-Brown Scale (Y-BOCS) s...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1159/000075110

    authors: Oliver B,Gascón J,Aparicio A,Ayats E,Rodriguez R,Maestro De León JL,García-Bach M,Soler PA

    更新日期:2003-01-01 00:00:00

  • Gamma knife stereotactic radiosurgical boost for patients treated primarily with neutron radiotherapy for salivary gland neoplasms.

    abstract:OBJECT:To determine the feasibility of utilizing a Gamma Knife stereotactic boost for patients at high risk of local recurrence from minor salivary gland tumors invading the base of skull. METHODS:Eight patients with minor salivary gland tumors invading the base of skull were treated with primary neutron radiotherapy ...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000077457

    authors: Douglas JG,Silbergeld DL,Laramore GE

    更新日期:2004-01-01 00:00:00

  • Gamma Knife radiosurgery for intracranial metastases: from local tumor control to increased survival.

    abstract::We have analyzed a series of 225 patients with intracranial metastases (343 lesions), treated in our department by Gamma Knife radiosurgery over a 30-month period. We have used a modified Pittsburgh protocol and performed 242 procedures on 164 single/78 multiple lesions. Primary tumors were mostly carcinomas of the lu...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000099809

    authors: Gerosa M,Nicolato A,Severi F,Ferraresi P,Masotto B,Barone G,Foroni R,Piovan E,Pasoli A,Bricolo A

    更新日期:1996-01-01 00:00:00

  • Stereotactic radiosurgery: current status and future trends.

    abstract::The first Gamma Knife was installed in Stockholm in 1968 after nearly two decades of development. Following the opening of the Gamma Knife facility in Pittsburgh in 1987, radiosurgery has seen an explosive expansion. Along with this expansion there has been a development of alternative technologies, of which the most ...

    journal_title:Stereotactic and functional neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Leksell DG

    更新日期:1993-01-01 00:00:00