Abstract:
:We present a system for surgical navigation using stereo overlays in the operating microscope aligned to the operative scene. This augmented reality system provides 3D information about nearby structures and offers a significant advancement over pointer-based guidance, which provides only the location of one point and requires the surgeon to look away from the operative scene. With a previous version of this system, we demonstrated feasibility, but it became clear that to achieve convincing guidance through the magnified microscope view, a very high alignment accuracy was required. We have made progress with several aspects of the system, including automated calibration, error simulation, bone-implanted fiducials and a dental attachment for tracking. We have performed experiments to establish the visual display parameters required to perceive overlaid structures beneath the operative surface. Easy perception of real and virtual structures with the correct transparency has been demonstrated in a laboratory and through the microscope. The result is a system with a predicted accuracy of 0.9 mm and phantom errors of 0.5 mm. In clinical practice errors are 0.5-1.5 mm, rising to 2-4 mm when brain deformation occurs.
journal_name
Stereotact Funct Neurosurgjournal_title
Stereotactic and functional neurosurgeryauthors
King AP,Edwards PJ,Maurer CR Jr,de Cunha DA,Hawkes DJ,Hill DL,Gaston RP,Fenlon MR,Strong AJ,Chandler CL,Richards A,Gleeson MJdoi
10.1159/000029708keywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
107-11issue
2-4eissn
1011-6125issn
1423-0372pii
29708journal_volume
72pub_type
杂志文章abstract::The underlying electrophysiologic abnormality in patients with chronic pain syndrome is demonstrated in 2 patients whose pain and associated symptoms were incapacitating. Mechanical perturbation evoked discharges most easily at the mesodiencephalic junction. Discharging tissue at that level appears to be oriented in b...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099499
更新日期:1989-01-01 00:00:00
abstract:OBJECT:To estimate the efficacy of Gamma Knife radiosurgery (GKR) especially as a primary surgical treatment for hypersecreting pituitary adenomas. METHODS:274 patients were treated with GKR. The mean tumor volume was 1.86 cm(3). The mean peripheral dose was 28.7 Gy. RESULTS:223 patients were followed up for an avera...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000048393
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Experimental data and case reports of patients with intractable epilepsy treated with deep brain stimulation (DBS) of the subthalamic nucleus (STN) suggest a considerable anticonvulsant effect. However, no satisfactory mechanisms of action have yet been elucidated. We investigated the putative therapeutic me...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000086867
更新日期:2005-01-01 00:00:00
abstract::Reinstallation of the Sheffield Gamma Knife Unit was completed in early November, 1991, following the replacement of the cobalt sources. Two methods were used to evaluate the isodose configuration within the replenished unit. The first method used a scanning microdensitometer to interrogate films exposed within a sphe...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100672
更新日期:1993-01-01 00:00:00
abstract::Twenty-five gliomas of the cerebral hemisphere in children were examined. Most hemispheric gliomas in children have relatively clear margins and less infiltrative potential. Radiosurgery has a role in the treatment of these tumors in addition to reducing the risk of radiation injuries developing later. Fifteen patient...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000099819
更新日期:1996-01-01 00:00:00
abstract::From January 1992 to November 1996, 17 patients with the diagnosis of intracranial meningioma underwent radiosurgical treatment. Of these, 7 patients were treated using a Linac-based system (group 1), and 10 using the Leksell Gamma Knife unit (group 2). The follow-up ranged between 12 and 48 (median 33) months for gro...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099869
更新日期:1997-01-01 00:00:00
abstract::The possible influence of painful stimulation and morphine analgesia on hypothalamic met-enkephalin levels, and the possible correlation between this biochemical parameter and animal behaviour was studied. The results indicate that both painful stimulation and morphine treatment induce an increase in hypothalamic mete...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100635
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:The neuropathological consequences of Gamma Knife radiosurgery (GK) on hypothalamic hamartoma (HH) are unknown. OBJECTIVE:In a cohort of patients undergoing surgery for treatment-resistant epilepsy, we compared surgically resected HH tissue from patients without (group I; n = 19) and with (group II; n = 10)...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000341076
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Hypothalamic hamartomas are associated with precocious puberty and chronic epilepsy characterized by gelastic seizures. The seizure disorder is usually refractory to most antiepileptic drugs. Gamma knife surgery has emerged as an alternative to microsurgical removal or radiofrequency ablation to improve seiz...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000094036
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:Stereotactic biopsies are subject to sampling errors (essentially due to target selection). The presence of contrast enhancement is not a reliable marker of malignancy. The goal of the present study was to determine whether perfusion-weighted imaging can improve target selection in stereotactic biopsies. MET...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000338092
更新日期:2012-01-01 00:00:00
abstract::The management of cerebral arteriovenous malformations (AVMs) continues to present a challenge to neurosurgeons. The natural history of this condition, as well as the morbidity and mortality of therapeutic interventions, remains incompletely elucidated. Predictive factors and grading scales in AVM management allow ris...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000126945
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Among the neuropsychiatric symptoms in Parkinson's disease (PD) patients, hallucination can result from the disease itself or medical treatment. Hallucination associated with subthalamic nucleus stimulation (STN-DBS) has been reported; however, it is still unclear whether PD patients with a history of halluc...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000195719
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Directional leads are increasingly used in deep brain stimulation. They allow shaping the electrical field in the axial plane. These new possibilities increase the complexity of programming. Thus, optimized programming approaches are needed to assist clinical testing and to obtain full clinical benefit. OBJ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000509781
更新日期:2020-10-20 00:00:00
abstract::Subacute and chronic continuous electrical stimulation at the epileptic focus in the hippocampus or parahippocampal cortex at 130 Hz, 0.21-1.0 ms, 2.5-3.5 V (about 200-300 microA) induces a decrease in focal EEG epileptic interictal activity and also in the occurrence of clinical seizures. This may represent an altern...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000064610
更新日期:2001-01-01 00:00:00
abstract::In order to shed light on the first application of human functional stereotactic neurosurgery, whether it was in the realm of movement disorders, as has been claimed repeatedly, or in the realm of psychiatry, a review of the original scholarly literature was conducted. Tracking and scrutinising original publications b...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000496157
更新日期:2019-01-01 00:00:00
abstract::Craniotomy using stereotactic techniques has the potential to improve the extent of tumor resection and to reduce wound and neurologic morbidity. Most reports of stereotaxy-assisted craniotomy (SC) for tumor resection have focused on techniques using sophisticated computer hardware and volumetric software. Results of ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000100625
更新日期:1993-01-01 00:00:00
abstract::Stiff limb syndrome (SLS) is a rare chronic condition which can result in significant debility. We report the case of a 44-year-old man suffering from severe painful spasms in his right leg with a diagnosis of SLS. He had been initially treated for his pain with a spinal cord stimulator but presented with exacerbation...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000313871
更新日期:2010-01-01 00:00:00
abstract::With the recent approval of reimbursement for positron emission tomography (PET), it has become important to clarify the utility of this diagnostic study. We evaluated the utility of PET to distinguish radiation necrosis from recurrent tumor in a retrospective review of patients with primary glial neoplasms. Fifteen p...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000029743
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:The optimum target in surgery for Parkinson's disease (PD) is still controversial, especially in patients with tremor-dominant PD. We aim to compare results in tremor-dominant patients undergoing pallidotomy vs. those undergoing simultaneous posteroventral pallidotomy (PVP) and ventral intermediate nucleus (...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000492229
更新日期:2018-01-01 00:00:00
abstract::Spinal cord stimulation (SCS) has been reported to be effective treatment for the failed back surgery syndrome in a number of retrospective case series. Its retrospectively reported results compare favorably with those of neurosurgical treatment alternatives, such as reoperation and ablative procedures. There has been...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000098631
更新日期:1994-01-01 00:00:00
abstract::The true accuracy of MRI scanners utilized for target acquisition in functional stereotaxis remains undefined. We have performed pallidotomies at the Loma Linda University Medical Center using both MRI and MRI concomitant with positive contrast ventriculography. A retrospective study of 33 cases revealed significant d...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000098897
更新日期:1995-01-01 00:00:00
abstract::Image-directed neurosurgical systems allow the correlation of a point in the operative field to a corresponding point on the patient's CT/MR scans. We have modified a surgical microscope by mounting three light-emitting diodes (LEDs) on a small frame attached to the microscope. The operative field was registered to th...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099675
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Internal neurolysis (IN) is an effective surgical treatment for trigeminal neuralgia (TN) without neurovascular compression (NVC) or postoperative recurrence. However, the trigeminal nerve is directly manipulated during the procedure, and there is a high incidence of trigeminocardiac reflex (TCR). The aim of...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000493547
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Applications in clinical medicine can benefit from fusion of spectroscopy data with anatomical imagery. For example, new 3-dimensional (3D) spectroscopy techniques allow for improved correlation of metabolite profiles with specific regions of interest in anatomical tumor images, which can be useful in charac...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000363751
更新日期:2014-01-01 00:00:00
abstract::Six patients with brain tumors within or near the primary motor cortex underwent preoperative functional magnetic resonance imaging (fMRI) and intraoperative cortical mapping, and the accuracy of those techniques for localization of the primary motor cortex and motor function beside the tumor were determined by compar...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000088160
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:The goal of the present study was to evaluate the effects of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) on olfaction in patients with Parkinson's disease (PD). METHODS:15 patients suffering from sporadic PD-related dysosmia were implanted with bilateral electrodes aimed at the ST...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000131662
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To evaluate the imaging and pathological correlates of successful or risk-related stereotactic radiosurgery (SR). Methods and Materials. The ten-year Gamma Knife experience in 2,344 patients at the University of Pittsburgh was reviewed. In addition, the results or radiosurgery primate, rat, and mouse models wer...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000056401
更新日期:1998-10-01 00:00:00
abstract::Out of 57 patients operated for intractable epilepsy of the central region, 8 harbored an indolent glioma (7 dysembryoplastic neuroepithelial tumors, 1 ganglioglioma). Mapping of the sensorimotor area with depth electrodes implanted for stereoelectroencephalographic exploration demonstrated no or abnormal motor respon...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099880
更新日期:1997-01-01 00:00:00
abstract::We identified 35 patients who had undergone stereotactic radiosurgery (SRS) for their biochemically proven Cushing's disease in order to assess the efficacy of SRS with regard to control of hypercortisolism, improvement of clinical features and prevention of tumor progression, and subsequent incidence of hypopituitari...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000083476
更新日期:2004-01-01 00:00:00
abstract::A simple device is described to perform lateral orthogonal approaches using the Leksell stereotactic frame. This device is especially useful for simultaneous bilateral insertion of intracerebral electrodes without the need for attaching the stereotactic arc. It also allows for targeting of far lateral lesions that lie...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100610
更新日期:1993-01-01 00:00:00