Abstract:
BACKGROUND/AIMS:Our study aimed to evaluate the efficiency and morbidity of Gamma Knife radiosurgery (GKS) in the treatment of hemorrhagic brainstem cavernous malformations (CMs). METHODS:We included in this study all patients who underwent GKS for the treatment of a hemorrhagic brainstem CM(s) in our institution between January 2007 and December 2012. The GKS was privileged when the surgical procedure was evaluated as very risky. The mean dose of radiation was 14.8 Gy, and the mean target volume was 0.282 cm3. All patients participated in a scheduled clinical follow-up. The posttreatment MRI was performed after 6 months and after 1 year, and then all patients had an annual MRI follow-up. RESULTS:There were 19 patients with a mean age of 36.7 years. The mean follow-up period was 51.2 months. The annual hemorrhage rate (AHR) was 27.31% before GKS, 2.46% during the first 2 years following the GKS, and 2.46% after the first 2 years following the GKS. The decrease in AHR after GKS was significant (p < 0.001). CONCLUSION:GKS should be suggested when the surgical procedure harbors a high risk of neurological morbidity in patients with brainstem CM. Compared to prior literature results, a lower dose than applied in this study could be discussed.
journal_name
Stereotact Funct Neurosurgjournal_title
Stereotactic and functional neurosurgeryauthors
Aboukais R,Estrade L,Devos P,Blond S,Lejeune JP,Reyns Ndoi
10.1159/000452844subject
Has Abstractpub_date
2016-01-01 00:00:00pages
397-403issue
6eissn
1011-6125issn
1423-0372pii
000452844journal_volume
94pub_type
杂志文章abstract::Out of 57 patients operated for intractable epilepsy of the central region, 8 harbored an indolent glioma (7 dysembryoplastic neuroepithelial tumors, 1 ganglioglioma). Mapping of the sensorimotor area with depth electrodes implanted for stereoelectroencephalographic exploration demonstrated no or abnormal motor respon...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099880
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Gamma knife surgery (GKS) is used at subnecrotic doses for temporal lobe epilepsy (TLE) treatment. Rat models of TLE have been used to probe the mechanisms underlying GKS. Previous GKS studies on rats have used the Leksell GammaPlan (LGP) treatment planning system to determine the irradiation time to achieve...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000314355
更新日期:2010-01-01 00:00:00
abstract::At the 1989 meeting of the World Society for Stereotactic and Functional Neurosurgery in Maebashi, the authors presented the concept and design of a stereotactic neurosurgical robot. The first prototype has now been completed and has entered clinical testing. The characteristics are as follows. The robot is positioned...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100300
更新日期:1994-01-01 00:00:00
abstract::The possible influence of painful stimulation and morphine analgesia on hypothalamic met-enkephalin levels, and the possible correlation between this biochemical parameter and animal behaviour was studied. The results indicate that both painful stimulation and morphine treatment induce an increase in hypothalamic mete...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100635
更新日期:1993-01-01 00:00:00
abstract::Autologous transplantation of the superior cervical ganglion (SCG) into the caudate nuclei of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian monkey was studied in regard to animal behavior and catecholamine (CA) metabolites in cerebrospinal fluid. Monkeys which had undergone autotransplantation of t...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100231
更新日期:1990-01-01 00:00:00
abstract:OBJECT:To estimate the efficacy of Gamma Knife radiosurgery (GKR) especially as a primary surgical treatment for hypersecreting pituitary adenomas. METHODS:274 patients were treated with GKR. The mean tumor volume was 1.86 cm(3). The mean peripheral dose was 28.7 Gy. RESULTS:223 patients were followed up for an avera...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000048393
更新日期:2000-01-01 00:00:00
abstract::A simple technique has been designed which identifies the gantry isocenter and aligns the laser beams to the isocenter of the gantry within 3-5 min with an error of less than 0.75 mm, depending upon the accuracy of gantry rotation. ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099516
更新日期:1989-01-01 00:00:00
abstract::We reviewed the initial experience with 331 consecutive patients treated during the first 2 years of operation of the University of Pittsburgh Gamma Unit. Among 178 patients with vascular malformations, 161 had angiographically demonstrable arteriovenous malformations, and 17 had angiographically occult malformations....
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100269
更新日期:1990-01-01 00:00:00
abstract::The authors present a series of 47 patients with craniopharyngiomas treated by stereotaxy in the past 15 years. There was no mortality nor immediate postoperative morbidity in the treatment of the cystic portion of the neoplasm. Intracavitary colloidal yttrium (90Y) was extremely effective in obtaining long-lasting di...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000098691
更新日期:1995-01-01 00:00:00
abstract::Currently, functional magnetic resonance imaging (fMRI) facilitates a preoperative awareness of an association of an eloquent region with a tumor. This information gives the neurosurgeon helpful information that can aid in creating a surgical strategy. Typically, task-based fMRI has been employed to preoperatively loc...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000442424
更新日期:2015-01-01 00:00:00
abstract::Stereotactic interventions at thalamic/subthalamic levels for parkinsonian tremor give the chance to investigate the influence of the supraspinal proprioceptive loops on the tonic component of motor tasks. Studies demonstrate not only a normalization of the late stretch reflex component and a decrease of the pre-refle...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100603
更新日期:1993-01-01 00:00:00
abstract::During a 16 years' period, a total of 79 dorsal root entry zone coagulations were performed in 68 patients for deafferentation pain. Of the 23 patients who underwent surgery for pain due to cervical root avulsion, 18 (82%) had a good (12) or fair (6) pain relief (mean follow-up period 51 months). Twelve (57%) patients...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099917
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:In nonresectable glioblastoma (GBM), stereotactic biopsies are performed to retrieve tissue for diagnostic purposes. The analysis of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation adds prognostic and predictive information. OBJECTIVES:The aim of the study was to detect confounding factor...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000360582
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Internal neurolysis (IN) is an effective surgical treatment for trigeminal neuralgia (TN) without neurovascular compression (NVC) or postoperative recurrence. However, the trigeminal nerve is directly manipulated during the procedure, and there is a high incidence of trigeminocardiac reflex (TCR). The aim of...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000493547
更新日期:2018-01-01 00:00:00
abstract::The rostral areas of the brainstem have been extensively studied in higher mammals and to a lesser extent in humans in the last two decades, looking for anatomical, electrophysiological and neurochemical evidence of involvement in the initiation and control of voluntary movement. This has come with the realisation tha...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000068961
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Rasmussen encephalitis (RE) is a rare progressive encephalitis that results in intractable seizures, cognitive decline and hemiparesis. Surgery seems to be the only effective way to control seizures in RE patients. OBJECTIVE:To describe the clinical, electrophysiological, neuroradiological and histological ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000355901
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:It is possible to judge the impact of scientific research by the number of citations a publication has received. We identified the most cited works in the field of stereotactic radiosurgery to study the evolution of this field from the perspective of publication. METHODS:A Web of Science search was performed...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000322277
更新日期:2011-01-01 00:00:00
abstract::Stiff limb syndrome (SLS) is a rare chronic condition which can result in significant debility. We report the case of a 44-year-old man suffering from severe painful spasms in his right leg with a diagnosis of SLS. He had been initially treated for his pain with a spinal cord stimulator but presented with exacerbation...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000313871
更新日期:2010-01-01 00:00:00
abstract::Somatosensory evoked potentials (SEP) were monitored intraoperatively in 15 patients who underwent spinal cord radiofrequency thermal dorsal root entry zone (DREZ) lesion procedures to treat chronic deafferentation pain. We found a significant correlation between transient latency shifts (recovery to prelesion values ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099539
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:To date, no consensus has been reached regarding validated and practical tools to quantify the severity of hemifacial spasm (HFS) before and after surgery. OBJECTIVE:The aim of this study has been to establish objective parameters for determining the preoperative severity of HFS and to assess the correlatio...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000330396
更新日期:2012-01-01 00:00:00
abstract::Electric stimulation applied to the posterior surface of the spinal cord (SCS) is an established treatment in certain chronic pain syndromes resistant to conventional therapeutic procedures. Despite the clinical value of SCS, the mechanisms behind the efficacy of the method are largely unknown. Several neurotransmitte...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100634
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:In well-designed multicenter studies, the protocol of continuing motor cortex stimulation (MCS) temporarily for 3-6 weeks was employed with rehabilitation therapy, and these studies showed some recovery of motor weakness in post-stroke patients. OBJECTIVES:We aimed to clarify the effects of long-term MCS an...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000332060
更新日期:2011-01-01 00:00:00
abstract::A prospective study on the effects of bilateral anterior capsulotomy in patients with refractory obsessive-compulsive disorder (OCD) is presented. A total of 18 procedures were performed in 15 patients. The mean duration of the OCDs was 18.1 +/- 5.6 years (range 11-26 years). The mean total Yale-Brown Scale (Y-BOCS) s...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000075110
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Writer's cramp is a specific movement disorder with hand muscle cramps in writing, being classified into focal and action-specific dystonia. Stereotactic surgery, such as thalamotomy and deep brain stimulation (DBS), has been reported for writer's cramp; however, the number of reported cases is still scarce ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000366004
更新日期:2014-01-01 00:00:00
abstract::The management of cerebral arteriovenous malformations (AVMs) continues to present a challenge to neurosurgeons. The natural history of this condition, as well as the morbidity and mortality of therapeutic interventions, remains incompletely elucidated. Predictive factors and grading scales in AVM management allow ris...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000126945
更新日期:2008-01-01 00:00:00
abstract::From January 1992 to November 1996, 17 patients with the diagnosis of intracranial meningioma underwent radiosurgical treatment. Of these, 7 patients were treated using a Linac-based system (group 1), and 10 using the Leksell Gamma Knife unit (group 2). The follow-up ranged between 12 and 48 (median 33) months for gro...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099869
更新日期:1997-01-01 00:00:00
abstract::We have analyzed a series of 225 patients with intracranial metastases (343 lesions), treated in our department by Gamma Knife radiosurgery over a 30-month period. We have used a modified Pittsburgh protocol and performed 242 procedures on 164 single/78 multiple lesions. Primary tumors were mostly carcinomas of the lu...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099809
更新日期:1996-01-01 00:00:00
abstract::Six patients with brain tumors within or near the primary motor cortex underwent preoperative functional magnetic resonance imaging (fMRI) and intraoperative cortical mapping, and the accuracy of those techniques for localization of the primary motor cortex and motor function beside the tumor were determined by compar...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000088160
更新日期:2005-01-01 00:00:00
abstract::The quantitative functional analysis of firing patterns has made it possible to classify human VL neurons into two basic types: (1), units with irregular unitary 3-to 20-imp/s activity (A type) and (2) units with short (10-30 ms) rhythmic (3-6 Hz) burst discharges (B type). These two basic types of VL neurons, determi...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100206
更新日期:1990-01-01 00:00:00
abstract::Image-directed neurosurgical systems allow the correlation of a point in the operative field to a corresponding point on the patient's CT/MR scans. We have modified a surgical microscope by mounting three light-emitting diodes (LEDs) on a small frame attached to the microscope. The operative field was registered to th...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099675
更新日期:1996-01-01 00:00:00