Changes in motor function induced by chronic motor cortex stimulation in post-stroke pain patients.

Abstract:

BACKGROUND:In well-designed multicenter studies, the protocol of continuing motor cortex stimulation (MCS) temporarily for 3-6 weeks was employed with rehabilitation therapy, and these studies showed some recovery of motor weakness in post-stroke patients. OBJECTIVES:We aimed to clarify the effects of long-term MCS and the optimal stimulation conditions to improve motor weakness in post-stroke patients. METHODS:We applied chronic MCS in 6 post-stroke pain patients with motor weakness. We then examined the correlation between the duration of daily MCS applied over 6 months and motor function assessed on the basis of the Fugl-Meyer Assessment (FMA) score of the patients. RESULTS:In the 6 patients with motor weakness, the FMA score of the upper extremity increased in 4 patients who underwent daily MCS for less than 4 h. On the other hand, 2 patients who continued excessive MCS to control their complicating post-stroke pain showed decreased FMA scores and worsened motor function owing to their increased rigidity and/or spasticity. These 2 patients recovered their motor function after their daily MCS was restricted to less than 4 h. CONCLUSIONS:These findings indicate that MCS could be a new therapeutic approach to improving motor performance after stroke by attenuating rigidity and/or spasticity. However, it may be important to define the appropriate number of hours and conditions of daily MCS.

authors

Yamamoto T,Katayama Y,Watanabe M,Sumi K,Obuchi T,Kobayashi K,Oshima H,Fukaya C

doi

10.1159/000332060

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

381-9

issue

6

eissn

1011-6125

issn

1423-0372

pii

000332060

journal_volume

89

pub_type

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