Abstract：
:We discuss the surgical approach used for and outcome in 11 infants (< or =3 years) who were treated at our institution for ependymomas arising in the cerebellar-pontine (C-P) angle. The median age of the group was 19 months (range: 6-26 months). Of these 11 patients, the initial surgery for 8 was performed at our center and achieved a gross total resection (GTR) in 4 patients and a subtotal resection (STR) in the remaining 4. The 3 patients who had tumor debulking performed elsewhere were subsequently referred to our institution and had definitive surgery after receiving 3-4 courses of chemotherapy; one of these children had a GTR, whereas the remaining 2 had an STR. During the immediate postoperative period, 9 patients had cranial nerve deficits that necessitated placement of a tracheostomy and a gastrostomy feeding tube; these were discontinued in 6 of the 9 patients as the deficits resolved. The majority of the permanent cranial nerve deficits involved the sixth and seventh cranial nerves. Of the 11 patients, 4 have died (progressive disease, n = 1; accidental death, n = 2; withdrawal of life support, n = 1); the remaining 7 patients are alive, with a median follow-up of 37 months (range: 20-73 months). Aggressive surgical resection for tumors arising in the C-P region is associated with postoperative deficits, which resolve over time with appropriate supportive care. This approach may increase the number of children in whom GTR is achieved, thereby potentially increasing the cure rate for these patients.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Sanford RA,Kun LE,Heideman RL,Gajjar Adoi
10.1159/000121232subject
Has Abstractpub_date
1997-08-01 00:00:00pages
84-91issue
2eissn
1016-2291issn
1423-0305journal_volume
27pub_type
杂志文章abstract：:Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are dire neurological disorders, characterized by severe damage to the myelin sheath of neurons, which typically result from rapid correction or overcorrection of systemic hyponatremia. For many years, both conditions have been considered universal...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章,评审
doi：10.1159/000320146
更新日期：2010-01-01 00:00:00
abstract：:A 4-year-old child with AIDS developed encephalitis 2 months prior to death. Adenovirus was cultured from the cerebrospinal fluid. At autopsy, sections of the brain revealed complete sloughing of the intracranial ependyma, with marked gliosis and edema of the periventricular white matter. Cells with large, dark, smudg...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000120551
更新日期：1990-01-01 00:00:00
abstract：:We report two children with hemihypertrophy and Chiari I malformation (CIM) and review the extant medical literature regarding CIM and overgrowth disorders. We propose that these two entities do not represent a spurious association but rather share a common dysembryology of mesoderm. ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000069820
更新日期：2003-05-01 00:00:00
abstract：:A rare case of a patient with Laurence-Moon-Biedl syndrome associated with hypothalamic hamartoma is described. The English-language literature contains no cases of patients with this association. The clinical manifestations of this syndrome, those of hypothalamic hamartomas, and the appearance of the tumors on magnet...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章,评审
doi：10.1159/000120563
更新日期：1991-01-01 00:00:00
abstract：INTRODUCTION:Traumatic posterior fossa extradural hematomas (PFEDH) are rare lesions constituting <10% of all extradural hematomas. Reliance on clinical findings alone is not recommended as these are nonspecific; for all suspicious cases, it is advisable to conduct a CT scan. Only a handful of pediatric studies have be...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000438488
更新日期：2015-01-01 00:00:00
abstract：:Encephaloceles arise from developmental defects in neural tube formation. These lesions contain brain and meninges which herniate through a defect in the skull. These may present as isolated malformations or rarely be associated with brain tumors. We hereby discuss a case of an unusual association of an occipital ence...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000339555
更新日期：2012-01-01 00:00:00
abstract：:Ongoing research in the etiology of neural tube defects is increasingly being directed towards the molecular mechanisms at work in the formation of these complex lesions. We undertook to review the family history of patients in a large myelomeningocele/spina bifida clinic in an effort to identify genetic trends in the...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000120977
更新日期：1995-01-01 00:00:00
abstract：:Radiotherapy has remained the mainstay of treatment for children with intrinsic, diffuse pontine tumors in spite of over 20 years of clinical trials attempting to validate the additional role of chemotherapy. Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas us...
journal_title：Pediatric neurosurgery
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1159/000121024
更新日期：1996-01-01 00:00:00
abstract：:The purpose of this study was to examine the current patterns of head trauma associated with child abuse. We reviewed the records of all patients admitted to our medical center between 1995 and 1997 with a primary diagnosis of head trauma, and analyzed the clinical presentation, mechanism of injury, socioeconomic stat...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000028880
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVES:The treatment of symptomatic cranio-vertebral junction (CVJ) instability in children affected by CVJ abnormalities is a challenge. A series of severely symptomatic children has been reviewed to understand the controversial long-term effectiveness of the aggressive management of CVJ abnormalities, in terms of...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000202621
更新日期：2009-01-01 00:00:00
abstract：:A 3-year-old boy with chronic papilledema, bilateral coronal synostosis and Pfeiffer syndrome underwent an orbitofrontal advancement. One month postoperatively, his papilledema had resolved, however, his vision progressively deteriorated over the ensuing 3 months to legal blindness. He had no symptoms or signs of incr...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000120913
更新日期：1995-01-01 00:00:00
abstract：:Molecular genetic analysis of several common cancers has yielded information concerning their etiology and prognosis. Restriction fragment length polymorphism (RFLP) studies showing consistent loss of specific DNA sequences in tumor tissue have identified genes, known as tumor suppressors, associated with the etiology...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章,评审
doi：10.1159/000120605
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Midline suboccipital craniotomy has been proposed as an alternative to conventional craniectomy for removal of posterior fossa tumors. METHOD:We describe a modified technique for midline suboccipital osteoplastic craniotomy based on the atlantooccipital membrane for a 17-year-old boy with superior vermian a...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000354220
更新日期：2012-01-01 00:00:00
abstract：:Six patients with hydrocephalus who were treated with cerebrospinal fluid (CSF) shunts became refractory to serosal absorption of CSF. All were subsequently treated with ventriculo-gallbladder shunts. The surgical technique and long-term results were evaluated by retrospective review of the hospital records. Detailed ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000121191
更新日期：1997-04-01 00:00:00
abstract：:We present a case report of a 21-month-old female patient to highlight magnetic resonance (MR) imaging findings associated with papilledema in a pediatric patient with an intracranial tumor. The MR findings included optic disc elevation, dilated perioptic subarachnoid spaces, optic nerve tortuosity and restricted diff...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000270156
更新日期：2009-01-01 00:00:00
abstract：:Tumors located in the region of the foramen of Monro often present with signs and symptoms of obstructive hydrocephalus. Various types of lesions occur in this location. We describe a case of a dysembryoplastic neuroepithelial tumor of the septum pellucidum presenting with obstructive hydrocephalus and its successful ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000090464
更新日期：2006-01-01 00:00:00
abstract：:The epidemiology of pediatric brain tumor was studied in a 10-year period from 1986 to 1995 in Yamaguchi prefecture. The total number of pediatric brain tumors was 83, and the incidence was 2.5/100, 000/year, which did not change during the period. The sign most frequently seen was intracranial hypertension, whereas f...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000028636
更新日期：1998-03-01 00:00:00
abstract：OBJECT:The evolution and severity of hydrocephalus in animal models varies in the species and mode of induction. This makes comparisons of the physiological system under investigation difficult between models. We noted that injection of kaolin into neonatal rats results in a dichotomous outcome into either an acute or ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000055975
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND/AIMS:The perception of a surgical complication may differ between surgeons and patients. In pediatric spine surgery, the perception of the parent or primary caregiver may also differ. In order to better define these relationships, we performed a pilot study surveying a convenience sample of pediatric spinal ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000319364
更新日期：2010-01-01 00:00:00
abstract：:Central pontine myelinolysis occurs inconsistently as a complication of severe and prolonged hyponatremia, particularly when corrected too rapidly. It is a concentrated, frequently symmetric, noninflammatory demyelination within the central basis pontis. We describe a head injury patient who suffered this clinical ent...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000315003
更新日期：2010-01-01 00:00:00
abstract：:We report a 16-year-old healthy boy who presented with sudden loss of vision in both eyes, accompanied by a mild headache. Magnetic resonance imaging showed a chiasmal apoplexy. An urgent craniotomy revealed a cavernous malformation of the chiasm, which was evacuated. There was a subsequent dramatic improvement in bil...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000149911
更新日期：2008-01-01 00:00:00
abstract：:We describe the initiation and development of a comprehensive multidisciplinary and multi-institutional program for the evaluation and management of youth with spasticity. A descriptive step-by-step process of the administrative and organizational sequence of the development of the program is delineated. The Spasticit...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1159/000355125
更新日期：2013-01-01 00:00:00
abstract：:Cystoperitoneal (CP) shunting is minimally invasive and achieves a high rate of resolution on neuroimaging. However, in the absence of definite symptoms, shunting should be reconsidered, because some patients can experience shunt dependency after CP shunting. In this study, the risk of shunt dependency in patients wit...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000065393
更新日期：2002-10-01 00:00:00
abstract：AIM:To evaluate the effectiveness of Novalis radiosurgery (RS) in children with optic gliomas. METHODS:Four pediatric patients (1 male and 3 female) were treated for optic gliomas with Novalis RS in our institution between February 2002 and July 2002. Their mean age was 12 (range 5-16) years at presentation for Novali...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000103305
更新日期：2007-01-01 00:00:00
abstract：:Endoscopic third ventriculostomy (ETV) provides a physiological restoration of cerebrospinal fluid and a shunt-free option for hydrocephalus children. Continuous developments in techniques and instruments have improved ETV as the first-line treatment. This paper focuses on the recent advances in surgical techniques, i...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章,评审
doi：10.1159/000491638
更新日期：2018-01-01 00:00:00
abstract：:Craniopharyngiomas can be divided into sellar, prechiasmatic, retrochiasmatic and giant tumors. The initial approach to a craniopharyngioma should be an attempt at its removal. Only if surgical therapy fails to deal with the tumor should more conservative approaches utilizing radiotherapy be used. The use of intracyst...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章,评审
doi：10.1159/000120861
更新日期：1994-01-01 00:00:00
abstract：:A needle for intravenous fluid administration in a newborn was accidentally placed in the sagittal sinus and resulted in dural sinus air embolism. CT findings are described and the risks for venous air embolism are discussed. ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000120606
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVE:To induce experimental split cord malformations (SCMs) produced through the surgical induction of a dorsal midline fistula. METHODS:In addition, the theory of embryogenesis of SCMs was verified by examining the developmental process of this experimentally induced anomaly. In Cynopus pyrrhogaster (amphibian) ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000058425
更新日期：2002-05-01 00:00:00
abstract：:The case of a child with Apert syndrome is presented in which the development and rupture of an intracranial mycotic aneurysm occurred secondary to multiple infectious complications following craniofacial surgery. An endovascular procedure was utilized in an attempt to embolize the aneurysm and parent vessel. The pati...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000050397
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:Composite-type split spinal cord malformation (SCM) is very rare and results from 2 separate foci of ectoendodermal adhesions and endomesenchymal tracts leading to the development of SCM with an intervening normal cord in the same patient. Posterior spurs are even rarer. We report a unique case of composite ...
journal_title：Pediatric neurosurgery
pub_type： 杂志文章
doi：10.1159/000336752
更新日期：2011-01-01 00:00:00
