Morphology of lipid alterations in the epidermis: a review.

Abstract:

:An overview of the morphological correlates of mammalian epidermal lipids and the cutaneous permeability barrier is provided. The following features are discussed: 1) ultrastructural characterization of the progressive lipid alterations accompanying normal stratum corneum (SC) formation; 2) effects of drugs/inhibitors that interfere with specific aspects of epidermal lipid metabolism; 3) lipid alterations in certain human skin disorders; 4) effects of selected topical emollients on SC lipid organization; and 5) potential pitfalls in interpretation of ultrastructural data in terms of cutaneous function and dysfunction.

journal_name

Microsc Res Tech

authors

Menon G,Ghadially R

doi

10.1002/(SICI)1097-0029(19970501)37:3<180::AID-JEM

subject

Has Abstract

pub_date

1997-05-01 00:00:00

pages

180-92

issue

3

eissn

1059-910X

issn

1097-0029

pii

10.1002/(SICI)1097-0029(19970501)37:3<180::AID-JEM

journal_volume

37

pub_type

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