Abstract:
:Vasoactive intestinal polypeptide (VIP) is a neuropeptide that has numerous physiological actions and is widely distributed in the body. However, as yet, there is no sequence information about VIP receptors in lower vertebrates. Partial cDNA fragments spanning transmembrane domains 2 to 6 of VIP receptors were isolated from six nonmammalian vertebrate species, including chicken, pigeon, frog, lizard, salmon, and goldfish. Sequence comparison of these receptors revealed essential structural motifs responsible for receptor function. In addition, the first nonmammalian full-length VIP receptor cDNA was obtained by screening a goldfish brain and pituitary cDNA library. Functional expression of this receptor in mammalian COS-7 cells showed that it is coupled to cAMP production in a VIP and PACAP concentration-dependent manner; the EC50 of VIP was determined to be 1 nM. At 100 nM peptide, the relative potency of various peptides in stimulating cAMP in the transfected cells was VIP > PACAP > GHRH = secretin > PHM > PTH > glucagon > GLP-1 > GIP. Characterization of the VIP receptors in lower vertebrates should enhance our understanding of the molecular evolution and physiology of VIP in vertebrates.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Chow BK,Yuen TT,Chan KWdoi
10.1006/gcen.1996.6818subject
Has Abstractpub_date
1997-02-01 00:00:00pages
176-85issue
2eissn
0016-6480issn
1095-6840pii
S0016-6480(96)96818-5journal_volume
105pub_type
杂志文章abstract::The aim of this work was to study, in the Cebus apella monkey, the developmental changes in the microanatomy of the utero-ovarian ligament (UOL) and whether their vascular and neural elements might be involved in the transfer of signals between the ovaries and uterus. Sections including uterus, UOL, and ovary obtained...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2005.06.006
更新日期:2005-12-01 00:00:00
abstract::The four-spine sculpin Cottus kazika is a euryhaline teleost, in which faster growth in seawater (SW) and freshwater (FW) has been reported. In this study, cDNA clones encoding growth hormone (GH) and insulin-like growth factor I (IGF-I) were isolated from this species to examine the involvement of the GH/IGF-I axis i...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/s0016-6480(02)00650-0
更新日期:2003-03-01 00:00:00
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journal_title:General and comparative endocrinology
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doi:10.1016/j.ygcen.2016.08.011
更新日期:2016-10-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1050
更新日期:1993-03-01 00:00:00
abstract::The photoperiodic control of puberty in birds was studied using hybrid red-legged partridges (Alectoris graeca chukar). In the wild partridges first breed at about 10 months of age. Males and females were held from hatch on short (8L:16D) daylengths and then at 3, 4 1/2, 6, 7 1/2, 9, and 12 weeks of age groups were tr...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(88)90290-0
更新日期:1988-07-01 00:00:00
abstract::The circulating serum concentrations of various steroid hormones in mature sockeye salmon were measured at four different developmental stages in their upstream migration to spawn at Adams River in British Columbia, Canada. In females, a high level of estradiol-17 beta was found in fish at the first location, and it p...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(86)90098-5
更新日期:1986-04-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.ygcen.2011.02.005
更新日期:2011-05-15 00:00:00
abstract::Glucagon and peptide of the neuropeptide Y (NPY) family immunoreactivities were studied in the gut of sea bass (Dicentrarchus labrax) using antisera against bovine/porcine glucagon, porcine glucagon, glicentin (10-30), bovine pancreatic polypeptide (PP), peptide tyrosine tyrosine (PYY), salmon PYY (sPYY), and NPY. Glu...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1998.7119
更新日期:1998-10-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1152
更新日期:1993-11-01 00:00:00
abstract::The maternal control directing the very first hours of life is of pivotal importance for ensuring proper development to the growing embryo. Thanks to the finely regulated inheritance of maternal factors including mRNAs and proteins produced during oogenesis and stored into the mature oocyte, the embryo is sustained th...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2016.03.028
更新日期:2017-05-01 00:00:00
abstract::Chicken growth hormone secretagogue receptor (GHSR) is a receptor for ghrelin (GHRL), a peptide hormone produced by chicken proventriculus, which stimulates growth hormone (GH) release and food intake. The purpose of this study was to search for single nucleotide polymorphisms (SNPs) in exon 2 of GHSR gene and to anal...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2016.08.016
更新日期:2016-10-01 00:00:00
abstract::Whether administration of the corticotropin-releasing factor (CRF) antagonist alpha-helical CRF(9-41) (hCRF) prevents stress response of the ovary, the oviduct, the adrenals, and the spleen was studied in the lizard Mabuya carinata. Stressors (handling, chasing, and noise) applied randomly, five times a day, for 1 mon...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.2002.7785
更新日期:2002-04-01 00:00:00
abstract::Reproduction of many temperate fishes is seasonal and maturation and spawning of gametes are under photothermal control. Reproductive success of first generation (G1) common sole Solea solea in captivity has been low. In this study, the sexual maturation status has been assessed during the prespawning months in G1 sol...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2014.12.004
更新日期:2015-09-15 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.2000.7571
更新日期:2000-12-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2013.10.002
更新日期:2013-12-01 00:00:00
abstract::Plasma levels of corticosterone and aldosterone were determined by radioimmunoassay in ducks consuming diets containing different concentrations of sodium and potassium. Compared with control diet birds, maintenance on a high-Na+ diet for 5 days caused a 2-fold increase in the basal plasma corticosterone concentration...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(85)90131-5
更新日期:1985-04-01 00:00:00
abstract::The occurrence of myoendocrine-like cells investing the ampullar draining region of Malpighian tubules and neighboring midgut and hindgut regions of the ant Formica polyctena is reported. These striated muscle cells show small electron-dense endocrine-like granules (130 +/- 0.95 nm) in addition to myofilaments and ord...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1994.1110
更新日期:1994-07-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(92)90031-e
更新日期:1992-08-01 00:00:00
abstract::In bony fishes, both corticotropin-releasing factor (CRF) and urotensin-I play a role in the regulation of interrenal glucocorticoid release. The rainbow trout, Oncorhynchus mykiss, is a useful model for understanding the mechanisms of stress and the hypothalamo-pituitary-interrenal axis because of its phylogenetic po...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1999.7290
更新日期:1999-08-01 00:00:00
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journal_title:General and comparative endocrinology
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更新日期:2003-10-15 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(91)90145-v
更新日期:1991-09-01 00:00:00
abstract::Cortisol is an important seawater (SW) osmoregulatory hormone in the Mozambique tilapia (Oreochromis mossambicus), a highly euryhaline cichlid able to live in environments ranging from fresh water (FW) to salinities well in excess of full-strength seawater. Previous studies indicate that cortisol may promote SW adapta...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/s0016-6480(03)00053-4
更新日期:2003-06-01 00:00:00
abstract::Regression of the müllerian ducts in mammals and birds is caused by the testicular hormone, müllerian inhibiting substance (MIS), which is produced for an extended period of time after testicular differentiation. Because it is present long after the ducts regress, it has been proposed to have additional effects other ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1994.1164
更新日期:1994-10-01 00:00:00
abstract::Deer antlers offer a unique model to study organ regeneration in mammals. Antler regeneration relies on the pedicle periosteum (PP) cells and is triggered by a decrease in circulating testosterone (T). The molecular mechanism for antler regeneration is however, unclear. Label-free liquid chromatography-mass spectromet...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2019.113235
更新日期:2019-11-01 00:00:00
abstract::The parathyroid glands of chickens were autotransplanted and the return of parathyroid function following transplantation was determined. Parathyroidectomy (PTX) resulted in a marked hypocalcemia (5.2 +/- 0.2 mg/dl) 4 hr following PTX. Plasma calcium (PCa) had declined to 4.3 +/- 0.2 mg/dl 24 hr after PTX. Parathyroid...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(89)90142-1
更新日期:1989-12-01 00:00:00
abstract::Plasma concentrations of growth hormone (GH) were decreased following the intravenous administration of morphine sulfate. Maximum inhibition of GH secretion was observed 40 min after morphine sulfate challenge. At this time, doses of morphine sulfate (at 5 mg and 50 mg/kg) reduced the GH concentrations by 86 and 90%, ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(87)90219-x
更新日期:1987-01-01 00:00:00
abstract::We have examined the distribution and physiological effects of three evolutionarily and sequence-related neuropeptides in Rhodnius prolixus. These neuropeptides, adipokinetic hormone (RhoprAKH), corazonin (CRZ) and adipokinetic hormone/corazonin-related peptide (RhoprACP) are present in distinct, non-overlapping neuro...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2013.10.012
更新日期:2014-01-01 00:00:00
abstract::To examine the production of steroids with potential oocyte maturation-inducing or pheromonal activity in the goldfish (Carassius auratus) we have incubated mature ovaries of this species with 17-[3H]hydroxyprogesterone. The metabolites in the unconjugated, glucuronide, and sulfate fractions were identified by chromat...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(92)90044-k
更新日期:1992-09-01 00:00:00
abstract::The developmental hypothesis proposes that the adrenocortical response to stress during postnatal development in birds should not develop when the benefits of elevated corticosterone do not outweigh the deleterious effects on growth and development. We tested three predictions developed from this hypothesis in free-li...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2010.06.009
更新日期:2010-09-15 00:00:00
abstract::Although present at relatively low number in the testis, spermatogonial stem cells (SSCs) are crucial for the establishment and maintenance of spermatogenesis in eukaryotes and, until recently, those cells were investigated in fish using morphological criteria. The isolation and characterization of these cells in fish...
journal_title:General and comparative endocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.ygcen.2014.06.018
更新日期:2014-10-01 00:00:00