[Laser Doppler flow signal frequency analysis in physiological and drug modified nasal flow motion].

Abstract:

:The term "flow motion" stands for the phenomenon of spontaneous and autonomous rhythmic variations of the contractile state of the smooth muscles of small dermal vessels. There also have been a few observations of variations in the microcirculation of the mucosa, but they have not been evaluated in detail to date. The aims of this study were to develop a method for investigation flow motion, especially in the nasal mucosa; to compare nasal flow motion to that of other skin and mucosal areas; to evaluate the influence of normal saline solution, as well as a sympathomimetic agent and histamine on flow motion. The microcirculation of the nasal mucosa of 40 healthy volunteers was measured under standardized conditions. In a first series of investigations, the microcirculations of the forehead, lobule of the ear, nose and oral mucosa were compared. In the second series, the microcirculation of the nasal mucosa was measured with laser-Doppler flowmetry before and after provocation with 0.9% saline solution, 0.25 mg oxymetazoline hydrochloride as sympathicomimetic preparation and 0.085 mg histamine in 0.5 ml of 0.9% saline solution. Evaluation of the data included signal analysis of the microcirculatory variations using fast-Fourier transformation and its changes before and after the pharmacological stimulations. Distribution of the power spectra showed that the nasal mucosa was significantly different from that of the skin of the forehead and the ear. Oxymetazoline hydrochloride led to a clear increase and histamine to a significant reduction in the frequencies of the flow motion. The results of this study demonstrated that nasal flow motion could be detected and evaluated with laser-Doppler flowmetry and a special analysis of the data recorded. Specific patterns of the flow motion frequencies could be detected in the nasal mucosa that were distinctive from those of the skin. The pattern of the flow motion frequencies reacted very sensitively to the pharmacological provocations used.

journal_name

HNO

journal_title

HNO

authors

Siegert R,Klitzing L

doi

10.1007/s001060050044

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

497-502

issue

9

eissn

0017-6192

issn

1433-0458

journal_volume

44

pub_type

杂志文章

相关文献

HNO文献大全
  • [Surgical management of sudden deafness (author's transl)].

    abstract::The conservative treatment of idiopathic sudden deafness generally shows good results. There are, however, some cases resistant to therapy which may be treated surgically by vestibulotomy. Reports are made on personal experiences as well as those of other authors. Vestibulotomy is recommended for those patients in who...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Tiedemann R,Börger U

    更新日期:1975-03-01 00:00:00

  • [Reconstruction of defects following pharyngolaryngectomy with free transplanted jejunum].

    abstract::We report 10 patients undergoing pharyngo-laryngectomy in whom the pharyngeal defect was reconstructed with a free jejunal graft. This method is technically demanding. The advantages are excellent healing due to the excellent blood supply of the edges of the graft, and the almost unlimited supply of jejunum. The use o...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Wicke W,Ehrenberger K,Grasl MC,Swoboda H,Piza H,Roka R

    更新日期:1986-06-01 00:00:00

  • [Sentinel lymphonodectomy as a staging method for head and neck cancer. Analysis of 70 patients].

    abstract:BACKGROUND:The excision of sentinel lymph nodes has a growing relevance in the diagnosis of oral and oropharyngeal cancer in cases of N0 necks. The validity of sentinel node biopsy (SNB) was examined as a single surgical staging tool. PATIENTS AND METHODS:Within the framework of a multi-modal treatment scheme, SNB wit...

    journal_title:HNO

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00106-004-1191-0

    authors: Kovács AF,Walendzik H,Döbert N,Menzel C

    更新日期:2005-06-01 00:00:00

  • [Angioedema in ENT practice].

    abstract::Angioedema is characterized by subcutaneous or submucosal swelling, which often affects the lips, tongue and oral or pharyngeal sites. Laryngeal oedema can be potentially life-threatening. The pathogenesis of angioedema is thought to involve the release of histamine and other mediators with subsequent extravasation of...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Poniewierski M,Laubert A

    更新日期:1989-04-01 00:00:00

  • [Hoarseness: biomechanisms and quantitative laryngoscopy].

    abstract::Every phonosurgical procedure alters endolaryngeal anatomy; be it by removing tissue, or injection or implantation of autologous or foreign material. However, the effect that an altered airflow cross section and changed soft tissue elasticity will have on the voice cannot be predicted. With the aim of promoting ration...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-014-2868-7

    authors: Eysholdt U

    更新日期:2014-07-01 00:00:00

  • [Who does my implant belong to? : A contribution to questions that everybody asks but no one can really answer].

    abstract:: ...

    journal_title:HNO

    pub_type: 杂志文章,评审

    doi:10.1007/s00106-018-0565-7

    authors: Wienke A

    更新日期:2019-02-01 00:00:00

  • [Congenital ranula in a newborn].

    abstract::Ranulas are cystic lesions in the floor of the mouth. They are either retention cysts of the excretory duct of the sublingual gland or pseudocysts formed by excretory duct rupture followed by extravasation and accumulation of mucus in the surrounding tissue. We report the case of a premature newborn with a congenital ...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-006-1409-4

    authors: Bernhard MK,Hückel D,Hamala D

    更新日期:2007-05-01 00:00:00

  • [Sinonasal hemangiopericytoma].

    abstract::Hemangiopericytomas are rare perivascular tumors. The nasal cavity and paranasal sinuses are most often involved in the head and neck region. A case of hemangiopericytoma in a 63 year old patient is presented. The initial symptom was recurrent bleeding from the nose. The patient had a history of radiotherapy for a pit...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-003-1030-8

    authors: Thomaser EG,Tschopp K,Oehri I,Carthomas G,Hailemariam S

    更新日期:2004-12-01 00:00:00

  • [Routine otorhinolaryngological examination in patients with cystic fibrosis].

    abstract:OBJECTIVES:Data on the prevalence of otorhinolaryngological (ORL) symptoms in patients with cystic fibrosis (CF) are limited. A standard annual examination would be useful for definition of risk factors and/or management alternatives for these symptoms. STUDY DESIGN:Prospective observational study of an unselected gro...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-005-1328-9

    authors: Koitschev A,Wolff A,Koitschev C,Preyer S,Ziebach R,Stern M

    更新日期:2006-05-01 00:00:00

  • [Post-traumatic aneurysm of the dorsal nasal artery. A rarity following blunt trauma].

    abstract::We report the case of a 69-year-old male patient who appeared in our clinic with persistent swelling on the right middle nasal bridge of 3 months' standing following blunt trauma. On physical examination the swelling was pulsatile and a flow was identified on color Doppler sonography. MRT of the head demonstrated an a...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-010-2220-9

    authors: Schuldt T

    更新日期:2010-12-01 00:00:00

  • [Ames test as biomarker].

    abstract:BACKGROUND AND OBJECTIVE:The incidence of squamous cell carcinomas in the upper aerodigestive tract has increased worldwide. The main risk factors are chronic tobacco and alcohol consumption. The detection of high-risk persons is important because early diagnosis of these tumors provides a good chance for permanent hea...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s001060170094

    authors: Bloching M,Stephan D,Agha-Mir-Salim P,Berghaus A,Lautenschläger C,Grummt T

    更新日期:2001-06-01 00:00:00

  • [Pharmacological characterization of head and neck cancer in ex-vivo tests].

    abstract::Precise knowledge about the chance of success of a given pharmacologic therapy of head and neck squamous cell carcinoma (HNSCC) before starting therapy would be very desirable to guide the selection of the most suitable or the most efficient combination out of the ever-growing spectrum of available pharmaceuticals. Th...

    journal_title:HNO

    pub_type: 杂志文章,评审

    doi:10.1007/s00106-011-2362-4

    authors: Wichmann G,Dietz A

    更新日期:2011-09-01 00:00:00

  • [Characterization of a closed-set logatome test : Documentation of audiometric data: discrimination function and reproducibility].

    abstract:BACKGROUND:Logatomes, nonsensical combinations of consonants and vowels, are suitable for a precise capture and analysis of individual phonemes as fundamental modules of speech in audiometric diagnostics. OBJECTIVE:The aim of this prospective study was to capture the audiometric characteristics of a closed-set logatom...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-019-00771-6

    authors: Hörmann L,Ambrosch P,Hey M

    更新日期:2020-01-01 00:00:00

  • [Fundamental frequency analysis - a contribution to the objective examination of the speaking and singing voice (author's transl)].

    abstract::The applicability of a newly developed fundamental frequency analyzer to diagnosis in phoniatrics is reviewed. During routine voice examination, the analyzer allows a quick and accurate measurement of fundamental frequency and sound level of the speaking voice, and of vocal range and maximum phonation time. By computi...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Schultz-Coulon HJ

    更新日期:1975-07-01 00:00:00

  • [Unilateral maxillary sinusitis: a cavernous haemangioma with bone destruction].

    abstract::Haemangioma originating in the paranasal sinuses are a rare entity. In the case of unilateral sinusitis the differential diagnosis should include tumors. The following case of a 30-year-old female patient with a therapy-resistant sinusitis showed bone destruction and a maxillary shadow on computed tomography. The hist...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-010-2225-4

    authors: Louza JP,Gürkov R,Weiler C,Krause E

    更新日期:2011-07-01 00:00:00

  • [Immunomodulation as innovative therapy for head and neck tumors : Current developments].

    abstract::Head and neck squamous cell carcinoma (HNSCC) is characterized by its intense immune suppression and its elaborate immune escape mechanisms. Due to the fact that survival rates remain low, the role of immunotherapy has become more important and the focus of current clinical studies has shifted toward antibody-based im...

    journal_title:HNO

    pub_type: 杂志文章,评审

    doi:10.1007/s00106-016-0131-0

    authors: Schuler PJ,Doescher JC,Laban S,Hoffmann TK

    更新日期:2016-07-01 00:00:00

  • [Giant Madelung's disease. Report of a case and review of the literature].

    abstract::Madelung's disease, also known as benign symmetrical lipomatosis, is a rare proliferative disorder of unknown etiology that was first mentioned by Brodie in 1846. Characterized by multiple symmetrical deposits of unencapsulated fat in the head and neck region, the disease is most common in middle-aged men with a histo...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-002-0629-5

    authors: Zeidler R,Lang S,Rasp G

    更新日期:2002-12-01 00:00:00

  • [Drug and psychological therapies in chronic subjective tinnitus. Meta-analysis of therapeutic effectiveness].

    abstract::A metaanalysis on pharmacological and psychological treatment reports was conducted in order to evaluate the overall effectiveness of these treatment conditions in chronic tinnitus. A totality of 109 treatment studies published between 1976 and 3/1995 and meeting minimal inclusion criteria was located, but only 24 stu...

    journal_title:HNO

    pub_type: 杂志文章,meta分析

    doi:10.1007/s001060050621

    authors: Schilter B,Jäger B,Heermann R,Lamprecht F

    更新日期:2000-08-01 00:00:00

  • [The indications for revision radical maxillary sinus surgery (author's transl)].

    abstract::Surgery of the maxillary sinus is one of the commonest in otorhinolaryngology. The classical Caldwell-Luc procedure however is not infrequently followed by infraorbital or some other facial neuralgia or discomfort. In 1976,246 patients were assessed for revision maxillary sinus surgery, and the symptomatology, clinica...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Thumfart W,Steiner W,Jaumann MP

    更新日期:1978-09-01 00:00:00

  • [Distraction and relaxation training in acute tinnitus : effects of a complement to otorhinolaryngological treatment].

    abstract:BACKGROUND:We examined whether training conceptualized as a complement to standard medical treatment (ST) for acute tinnitus to promote patients' capacity to distract attention from their tinnitus and to relax (distraction and relaxation training) has a positive effect on tinnitus-specific distress (tinnitus loudness, ...

    journal_title:HNO

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00106-009-2019-8

    authors: Gerhards F,Brehmer D

    更新日期:2010-05-01 00:00:00

  • [An intraosseous hemangioma in the perpendicular lamina of the ethmoid bone].

    abstract::The incidence of intraosseous hemangiomas is very low. Most of them occur in adult females. The mandible,the zygoma,the maxilla, and the frontal and nasal bones are the areas of most frequent localization in the facial region. The intraosseous hemangioma is a benign, slowly growing,bony hard tumor causing facial defor...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-002-0678-9

    authors: Graumüller S,Terpe H,Hingst V,Dommerich S,Pau HW

    更新日期:2003-02-01 00:00:00

  • [Failed intubation with case reports].

    abstract::Failed intubation in three patients is reported. All three patients suffered sudden, extreme impaired of mask-ventilation. Twice a coniotomy with subsequent tracheostomy proved to be life saving and without permanent injury. In the other patient tracheostomy had been attempted without success, and subsequent, successf...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Steinert R,Lüllwitz E

    更新日期:1987-10-01 00:00:00

  • [Functional plastic surgery of inflamed cavities: the fascination of tympanoplasty].

    abstract::Reconstructive middle ear surgery was introduced in the early fifties. Kley was one of the first to investigate the applicability of grafts and the functional restoration of the middle ear transformer. He also practiced a combined approach with anterior tympanoplasty and posterior mastoidectomy. On the occasion of his...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Wigand ME

    更新日期:1987-08-01 00:00:00

  • [Rhinological aspects in transseptal pituitary surgery (author's transl)].

    abstract::Ozaena used to be the most common rhinological complication following transnasal pituitary surgery. The development of subtle microsurgical techniques has significantly reduced this risk, and the transrhinoseptal approach to the pituitary fossa has become the method of choice. The surgical technique is described. 20 p...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Rama B,Schröder M

    更新日期:1982-03-01 00:00:00

  • [Magnesium content of laryngeal precancerous conditions and laryngeal cancers].

    abstract::The content of magnesium in tissues, erythrocytes and serum was analysed by atomic absorption spectrometry. A higher concentration of magnesium was found in malignant laryngeal tissue and in lymph nodes of the neck compared to homologous pre-cancerous tissue. In pre-cancerous lesions of the larynx the magnesium concen...

    journal_title:HNO

    pub_type: 杂志文章

    doi:

    authors: Szmeja Z,Kończewska H

    更新日期:1986-02-01 00:00:00

  • [De-escalation concepts for chemoradiotherapy of HPV-positive oropharyngeal carcinomas: pros and cons].

    abstract:BACKGROUND:In contrast to alcohol- and nicotine-induced head and neck tumors, human papillomavirus (HPV)-positive oropharyngeal carcinoma rather affects younger patients, and the incidence of this entity is continuously increasing. Due to the significantly better prognosis of HPV-positive oropharyngeal carcinoma, vario...

    journal_title:HNO

    pub_type: 杂志文章,评审

    doi:10.1007/s00106-020-00955-5

    authors: Rühle A,Nicolay NH

    更新日期:2020-10-13 00:00:00

  • [Solitary neurofibroma of the parapharyngeal space].

    abstract::A 21 year old male patient presented with dysphagia. Clinical examination as well as CT and MRT showed a tumor in the right parapharyngeal space. The tumor was resected completely using a transcervical approach. The pathological examination showed a neurofibroma. In this case report, preoperative diagnosis, therapy an...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-003-0871-5

    authors: Wenke KA,Jäckel MC

    更新日期:2004-05-01 00:00:00

  • [Voice change and laryngeal obstruction caused by a median thyroglossal duct cyst].

    abstract::Thyroglossal duct cysts are common primary neck tumors, resulting from remnants of the ductus thyroglossus. They can occur at any point along the migratory path of the thyroid gland anlage until the 2nd or 3rd decade of life. The usual symptoms leading to the diagnosis are painless midline neck masses orfistulas. Desp...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s001060050707

    authors: Lübben B,Alberty J,Lang-Roth R,Stoll W,Seifert E

    更新日期:2001-01-01 00:00:00

  • [Evaluation of the Oldenburg children's rhyme test in silence and in noise].

    abstract:BACKGROUND:The Oldenburg children's rhyme test (OlKi) was designed and optimized for speech intelligibility measurements for primary school pupils in silence [8, 3]. In the optimization, the intelligibility of the particular test words was equalized. METHODS:The evaluation of the test with 147 primary school pupils wi...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s00106-005-1304-4

    authors: Wagener KC,Brand T,Kollmeier B

    更新日期:2006-03-01 00:00:00

  • [Individual differences in susceptibility to motion sickness].

    abstract::Several different theories exist about the origin of kinetosis and the space adaptation syndrome, with individual sensitivities differing significantly. One explanation involves the hypothesis of a different otolith mass between the right and left statolith organ and especially a difference in the utricles. A differen...

    journal_title:HNO

    pub_type: 杂志文章

    doi:10.1007/s001060050106

    authors: Helling K,Hausmann S,Flöttmann T,Scherer H

    更新日期:1997-04-01 00:00:00