Concussion.

abstract：OBJECTIVE:To present a multiyear clinical experience with intravenous bevacizumab for the management of severe gastrointestinal bleeding and/or epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT). PATIENTS AND METHODS:All patients treated with intravenous bevacizumab for severe hereditary hemorrhagi...

journal_title：Mayo Clinic proceedings

authors： Iyer VN,Apala DR,Pannu BS,Kotecha A,Brinjikji W,Leise MD,Kamath PS,Misra S,Begna KH,Cartin-Ceba R,DuBrock HM,Krowka MJ,O'Brien EK,Pruthi RK,Schroeder DR,Swanson KL

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To quantify the impact of the severe acute respiratory syndrome coronavirus 2 pandemic on emergency department volumes and patient presentations and evaluate changes in community mortality for the purpose of characterizing new patterns of emergency care use. PATIENTS AND METHODS:This is an observational cros...

journal_title：Mayo Clinic proceedings

authors： Walker LE,Heaton HA,Monroe RJ,Reichard RR,Kendall M,Mullan AF,Goyal DG

更新日期：2020-11-01 00:00:00

abstract：:Stereotactic ventralis lateralis thalamotomy can be performed in selected patients with medically intractable parkinsonian tremor and rigidity. New technology, including computed tomography-based stereotaxis and microelectrode recording techniques, provides a data base for precise localization of thalamic lesions tail...

journal_title：Mayo Clinic proceedings

authors： Kelly PJ,Ahlskog JE,Goerss SJ,Daube JR,Duffy JR,Kall BA

更新日期：1987-08-01 00:00:00

abstract：:The metabolic syndrome is an insulin-resistant state characterized by a cluster of cardiovascular risk factors, including various combinations of abdominal obesity, glucose intolerance, hypertension, and atherogenic dyslipidemia (elevated triglyceride values, low high-density lipoprotein cholesterol levels, and small ...

journal_title：Mayo Clinic proceedings

authors： Johnson LW,Weinstock RS

更新日期：2006-12-01 00:00:00

abstract：:Cardiorespiratory fitness (CRF) is an established risk factor for cardiovascular disease outcomes. However, the relationship of CRF with risk of ventricular arrhythmias (VAs) is unknown. We aimed to assess the prospective association of CRF with the risk of serious VAs. Cardiorespiratory fitness, as measured by maxima...

journal_title：Mayo Clinic proceedings

authors： Laukkanen JA,Lavie CJ,Khan H,Kurl S,Kunutsor SK

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To describe the history, objectives, statistics, and initiatives used to address challenges associated with the Mayo Clinic Visiting Medical Student (VMS) Clerkship Program. MATERIALS AND METHODS:Mayo Clinic administrative records were reviewed for calendar years 1995 through 2008 to determine the effect of ...

journal_title：Mayo Clinic proceedings

authors： Mueller PS,McConahey LL,Orvidas LJ,Jenkins SM,Kasten MJ

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To describe clinical and laboratory findings from the 2012 southeastern Minnesota pertussis outbreak. PATIENTS AND METHODS:Patients were selected for 2 parts of the study. In the first part, nasopharyngeal swabs from a convenience sample of 265 unique patients were used for both the clinician-requested polym...

journal_title：Mayo Clinic proceedings

authors： Theofiles AG,Cunningham SA,Chia N,Jeraldo PR,Quest DJ,Mandrekar JN,Patel R

更新日期：2014-10-01 00:00:00

abstract：:All women who enter menopause experience amenorrhea unless they receive hormone replacement therapy. In younger women, amenorrhea unrelated to pregnancy and lactation can be a distressing symptom. In addition to its psychologic morbidity, amenorrhea may be the manifesting feature of a wide array of anatomic and endocr...

journal_title：Mayo Clinic proceedings

authors： McIver B,Romanski SA,Nippoldt TB

更新日期：1997-12-01 00:00:00

abstract：:In this report, we describe 13 cases of primary neurofibrosarcoma of the skin. The tumor presumably arises from small cutaneous nerves, is locally aggressive, and has a potential for metastasis. Characteristic histopathologic features include proliferating atypical spindle cells with slender wavy and pointed nuclei; h...

journal_title：Mayo Clinic proceedings

authors： Dabski C,Reiman HM Jr,Muller SA

更新日期：1990-02-01 00:00:00

abstract：:Prospective data and follow-up information were collected on the initial 200 patients who underwent laparoscopic cholecystectomy at the Mayo Clinic. The operation was completed laparoscopically in all but five patients, who required conversion to laparotomy because of dense scarring or stones in the common bile duct. ...

journal_title：Mayo Clinic proceedings

authors： Donohue JH,Farnell MB,Grant CS,van Heerden JA,Wahlstrom HE,Sarr MG,Weaver AL,Ilstrup DM

更新日期：1992-05-01 00:00:00

abstract：:Plasma concentration of brain natriuretic peptide (BNP), as measured by the Triage BNP Test, is approved by the Food and Drug Administration to aid in the diagnosis of heart failure. This diagnostic test is available in many institutions. The purpose of this article is to help the physician know the appropriate time t...

journal_title：Mayo Clinic proceedings

authors： Shapiro BP,Chen HH,Burnett JC Jr,Redfield MM

更新日期：2003-04-01 00:00:00

abstract：:Of the 355 patients with tuberous sclerosis complex (TSC) examined at the Mayo Clinic, 49 had died (9 of causes other than TSC). We attempted to determine what pattern of organ involvement occurred most often in the 40 patients who died of TSC. One baby died of cardiac failure due to cardiac rhabdomyomas, and one chil...

journal_title：Mayo Clinic proceedings

authors： Shepherd CW,Gomez MR,Lie JT,Crowson CS

更新日期：1991-08-01 00:00:00

abstract：:During the 1960s, the Mustard or Senning operation was the conventional palliative therapy for patients with transposition of the great arteries. Many of these patients are now adults, and the durability of the morphologic right ventricle to function as the systemic ventricle is being questioned. Surgical options for ...

journal_title：Mayo Clinic proceedings

authors： Cetta F,Bonilla JJ,Lichtenberg RC,Stasior C,Troman JE,Deleon SY

更新日期：1997-03-01 00:00:00

abstract：:The Human Genome Project has resulted in a new era in the field of pharmacogenetics in which researchers are rapidly discovering new genetic variation, which may help to explain interindividual variability in drug efficacy and toxicity. Pharmacogenetics is the study of the role of genetic inheritance in individual var...

journal_title：Mayo Clinic proceedings

authors： Goetz MP,Ames MM,Weinshilboum RM

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To examine 45-year trends in time use and physical activity energy expenditure (PAEE) in a nationally representative sample of US mothers. PARTICIPANTS AND METHODS:We quantified time allocation to physical activity (PA), sedentary behaviors (SED), and PAEE from 1965 to 2010 in mothers with older children (MO...

journal_title：Mayo Clinic proceedings

authors： Archer E,Lavie CJ,McDonald SM,Thomas DM,Hébert JR,Taverno Ross SE,McIver KL,Malina RM,Blair SN

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the use of a computerized bar code-based blood identification system resulted in a reduction in transfusion errors or near-miss transfusion episodes. PATIENTS AND METHODS:Our institution instituted a computerized bar code-based blood identification system in October 2006. After instituti...

journal_title：Mayo Clinic proceedings

authors： Nuttall GA,Abenstein JP,Stubbs JR,Santrach P,Ereth MH,Johnson PM,Douglas E,Oliver WC Jr

更新日期：2013-04-01 00:00:00

abstract：:Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component o...

journal_title：Mayo Clinic proceedings

authors： DiNicolantonio JJ,O'Keefe JH,Lucan SC

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To determine whether N-acetylcysteine rinse was safe and could improve thickened secretions and dry mouth during and after radiotherapy. PATIENTS AND METHODS:We designed a prospective pilot double-blind, placebo-controlled randomized clinical trial (Alliance MC13C2). Adult patients (age ≥18 years) were enrol...

journal_title：Mayo Clinic proceedings

authors： Sio TT,Blanchard MJ,Novotny PJ,Patel SH,Rwigema JM,Pederson LD,McGee LA,Gamez ME,Seeger GR,Martenson JA,Grover Y,Neben Wittich MA,Garces YI,Foote RL,Miller RC,Halyard MY

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and distribution of radical prostatectomy (RP) in the United States over time. PATIENTS AND METHODS:We conducted a serial cross-sectional analysis of time trends using the Nationwide Inpatient Sample of adult men older than 45 years who underwent RP between January 1, 1998, and Dec...

journal_title：Mayo Clinic proceedings

authors： Tyson MD 2nd,Andrews PE,Ferrigni RF,Humphreys MR,Parker AS,Castle EP

更新日期：2016-01-01 00:00:00

abstract：:Breast cancer is the most common noncutaneous malignancy among every major ethnic group of women in the United States. Anthracyclines and taxanes are the most active and widely used chemotherapeutic agents for breast cancer, but the increased use of these agents at an early stage of disease often renders tumors resist...

journal_title：Mayo Clinic proceedings

authors： Moreno-Aspitia A,Perez EA

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To define age-adjusted incidence trends in multiple myeloma (MM) in a well-characterized population during a long period, given that some, but not all, studies have reported increasing MM incidence over time and that clinical experience from some centers suggests an increased incidence mainly in younger age g...

journal_title：Mayo Clinic proceedings

authors： Turesson I,Velez R,Kristinsson SY,Landgren O

更新日期：2010-03-01 00:00:00

abstract：:Frequently, the presence of endocarditis is disguised. The emphasis of this description of the clinical manifestations of endocarditis is on the various modes of presentation, rather than on individual symptoms and signs. Endocarditis can manifest with cardiac, pulmonary, ophthalmic, central nervous system, renal, ort...

journal_title：Mayo Clinic proceedings

authors： Hermans PE

更新日期：1982-01-01 00:00:00

abstract：:Ocular adnexal lymphoproliferative lesions consist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. No clinical or radiologic criteria facilitate a distinction among these lymphoproliferative lesions. The two hyperplastic processes may evolve to l...

journal_title：Mayo Clinic proceedings

authors： Liesegang TJ

更新日期：1993-10-01 00:00:00

abstract：:Advances in liver transplantation continue to evolve but are hampered by continued increasing shortages in donor organs. This has resulted in a high incidence of patients dying while on the United Network for Organ Sharing waiting list. Indeed, we continue to assess ways of expanding the donor pool by using marginal d...

journal_title：Mayo Clinic proceedings

authors： Wiesner RH,Rakela J,Ishitani MB,Mulligan DC,Spivey JR,Steers JL,Krom RA

更新日期：2003-02-01 00:00:00

abstract：:There appears to be a spectrum of psychogenic urinary retention that is seen mostly in women. The degrees of psychiatric disorder and bladder disorder do not necessarily coincide. Some patients with psychogenic retention may have one acute episode temporally related to psychologic trauma. Others may present with probl...

journal_title：Mayo Clinic proceedings

authors： Barrett DM

更新日期：1976-06-01 00:00:00

abstract：:Platelets from normal pigs and pigs with von Willebrand's disease were studied by ultrastructural and scanning electron microscopy. The majority of resting platelets were discoid or abortive-dendritic in gross morphology with an average size of 2.6 micrometer. The number of alpha-granules per platelet section was vari...

journal_title：Mayo Clinic proceedings

authors： Lewis JC,Bowie FJ

更新日期：1978-03-01 00:00:00

abstract：:With the ever-expanding elderly population in the United States, benign prostatic hyperplasia (BPH) has become a widespread condition. Although surgical intervention (open prostatectomy and transurethral resection of the prostate) was the typical management approach for BPH in the past, other options currently include...

journal_title：Mayo Clinic proceedings

authors： Blute ML,Larson TR,Hanson KA,King BF

更新日期：1998-06-01 00:00:00

abstract：:We measured cardiopulmonary function at rest and during exercise in 15 healthy survivors of neonatal respiratory distress syndrome (RDS) and compared the results with those in 15 normal subjects. The mean birth weight of the RDS group was 1,771 g, and 12 of the 15 patients had required endotracheal intubation. The oxy...

journal_title：Mayo Clinic proceedings

authors： Driscoll DJ,Kleinberg F,Heise CT,Staats BA

更新日期：1987-08-01 00:00:00

abstract：:A 27-year-old man with a history of acne presented to his primary care physician because of fatigue and dyspnea on exertion of 4 weeks' duration. He was remarkably pale, orthostatic pulse changes were noted, and a systolic ejection murmur was heard. The patient had profound anemia (hemoglobin concentration, 5.0 g/dL) ...

journal_title：Mayo Clinic proceedings

authors： Igic PG,Lee E,Harper W,Roach KW

更新日期：2002-07-01 00:00:00

abstract：:Benign prostatic hyperplasia (BPH), a nonmalignant neoplasm of the prostatic epithelial and stromal tissue, occurs commonly in elderly men. The "gold standard" of care for symptomatic BPH has been and remains transurethral resection of the prostate. This operation, however, like any surgical procedure, has associated ...

journal_title：Mayo Clinic proceedings

authors： Monda JM,Oesterling JE

更新日期：1993-07-01 00:00:00