Abstract：
:We studied intermanual motor transfer for right-to-left or left-to-right direction of transfer between either proximal or distal upper extremity muscle groups. The influence of previously acquired motor engrams (original learning, OL) on learning efficiency of the contralateral side (transfer learning, TL) was examined in 26 right-handed healthy subjects. The task consisted of the drawing of meaningless figures. During TL, OL figures had to be reproduced as vertical mirror reversals. Data revealed a benefit for right-to-left but not left-to-right direction of transfer for time to complete a figure as well as a left-to-right transfer benefit for spatial motor precision. Furthermore, a benefit for intermanual transfer of training between proximal but not distal muscle groups was found when movement time to complete a figure was evaluated. Of special interest was the observation of a disadvantage due to prior contralateral learning for performance at right distal effectors. The asymmetrical transfer benefits with respect to side are in line with previous findings and support the proficiency model and the cross-activation model. Results further showed that intermanual transfer of training might differ with respect to muscle group involvement and suggest that, although primarily facilitating, previous opposite hand training may lead to inhibitory influences on subsequent contralateral reproduction.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Thut G,Cook ND,Regard M,Leenders KL,Halsband U,Landis Tdoi
10.1007/BF00228105subject
Has Abstractpub_date
1996-03-01 00:00:00pages
321-7issue
2eissn
0014-4819issn
1432-1106journal_volume
108pub_type
临床试验,杂志文章abstract：:The amyloid precursor protein (APP) has a pivotal role in pathogenesis of Alzheimer's disease (AD) via its beta- and gamma-secretase-derived cleavage products--the A-beta peptides. An alternative processing pathway provided by the alpha-secretase prevents formation of those toxic peptides and gives rise to the neurotr...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-011-2885-7
更新日期：2012-04-01 00:00:00
abstract：:The ability to precisely time events is essential for both perception and action. There is evidence that the cerebellum is important for the neural representation of time in a variety of behaviors including time perception, the tapping of specific time intervals, and eye-blink conditioning. It has been difficult to as...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0857-8
更新日期：2007-06-01 00:00:00
abstract：:The purpose of this study was to determine whether the neuromuscular control of goal-directed movements is different for young and older adults with the upper and lower limbs. Twenty young (25.1 ± 3.9 years) and twenty older adults (71.5 ± 4.8 years) attempted to accurately match the displacement of their limb to a sp...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3868-2
更新日期：2014-06-01 00:00:00
abstract：:The distribution and morphology of developing corpus callosum (CC) axons in rat visual cortex was studied by unilateral application of the in vivo anterograde tracer biotinylated dextran amine (BDA) to the visual or auditory cortex of newborns through adults. Changes in the distribution and morphology of CC axons duri...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000576
更新日期：2001-01-01 00:00:00
abstract：:Projections from the posterior thalamic regions to the striatum were studied in the cat by the anterograde tracing method after injecting wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) into the caudalmost regions of the lateroposterior thalamic nucleus (caudal LP), suprageniculate nucleus (Sg) and ma...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235934
更新日期：1985-01-01 00:00:00
abstract：:Experiments using the same glass microelectrode (6--8 M omega) for recording and stimulating were performed on 12 rats in which 379 cortical cells were studied in 65 penetrations through the motor and somatosensory cortical zones. To avoid anaesthetic effects the rats were chronically implanted with a head system deri...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238808
更新日期：1981-01-01 00:00:00
abstract：:Inhibition of return (IOR) is thought to reflect a bias against returning attention to previously attended locations. According to this view, IOR should occur only if attention is withdrawn from the target location prior to target appearance. In the present study, endogenous attention and exogenous cueing were manipul...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-004-1963-5
更新日期：2004-12-01 00:00:00
abstract：:In walking cats decerebrated at the premammillary level, single neurone activity of Purkinje cells (P-cells) with long corticofugal axons was recorded in the cerebellar vermis. The P-cells (N = 145) were identified as they showed spontaneous simple and complex spikes and also antidromic activation from Deiters' nucleu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238886
更新日期：1981-01-01 00:00:00
abstract：:Vection is the illusion of self-motion in the absence of real physical movement. The aim of the present study was to analyze how multisensory inputs (visual and auditory) contribute to the perception of vection. Participants were seated in a stationary position in front of a large, curved projection display and were e...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3793-9
更新日期：2014-03-01 00:00:00
abstract：:The goal of this study was to identify the control mechanism used for locomotion pointing regulation under different external temporal constraints. Subjects ( n=8) had to walk on a treadmill through a number of virtual hallways and cross a pair of gliding doors that opened and closed at a constant preset frequency (0....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0990-8
更新日期：2002-03-01 00:00:00
abstract：:In order to study neuronal information transfer from the striatum to the globus pallidus (GP) during voluntary movement, we recorded activity of electrophysiologically identified projection neurons in the putamen to the GP while the monkey was performing learned movement tasks. Two categories of putamen neurons were r...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228811
更新日期：1990-01-01 00:00:00
abstract：:The evoked expression of the immediate early gene-encoded proteins c-Fos and Krox-24 was used to study activation of hindbrain neurons as a function of the development of cyclophosphamide (CP) cystitis in behaving rats. CP-injected animals received a single dose of 100 mg/kg i.p. under transient volatile anesthesia an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227263
更新日期：1996-03-01 00:00:00
abstract：:Previous investigations have revealed that perceived spatial frequency of gratings rises as contrast is lowered. In order to account for this finding it has been postulated that the spatial frequency which produces the maximum response from cortical neurones decreases with contrast. We have examined this hypothesis by...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236862
更新日期：1986-01-01 00:00:00
abstract：:The photothrombotic ring stroke model with sustained underperfusion followed by late spontaneous reperfusion (Gu et al. 1999) was employed to study its morphological consequences. The exposed crania of adult male Wistar rats were subjected to a ring-shaped laser irradiation beam simultaneously with intravenous erythro...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050672
更新日期：1999-03-01 00:00:00
abstract：:After minimizing proprioceptive input from the legs by ischemia without degradation of muscle force and excluding visual stabilization by eye closure, a characteristic anterior-posterior postural sway around 1 Hz was observed in three normal subjects. This is similar to the instability seen in two tabes dorsalis patie...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237939
更新日期：1980-01-01 00:00:00
abstract：:The microtubule associated tau protein becomes hyperphosphorylated in Alzheimer's disease (AD). While hyperphosphorylation promotes neurodegeneration, the cause and consequences of this abnormal modification are poorly understood. As impaired energy metabolism is an important hallmark of AD progression, we tested whet...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5341-0
更新日期：2018-11-01 00:00:00
abstract：:Sequential intraocular grafting of defined areas from fetal rat brain to adult host rats was used to explore the possibility that such double grafts would become interconnected. Norepinephrine- containing neurons of the locus coeruleus were grafted together with either parietal cerebral cortex, hippocampus, or the cau...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236784
更新日期：1979-03-09 00:00:00
abstract：:Is it possible to learn to perform a motor sequence without awareness of the sequence? In two experiments, we presented participants with the most elementary sequence: an alternation between two options. We used a double-step pointing task in which the final position of the target alternated between two quite similar ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4566-z
更新日期：2016-06-01 00:00:00
abstract：:The effect of unilateral vestibular deafferentation (UVD) on the linear vestibulo-ocular reflex (LVOR) was studied in 11 humans an average of 52 months following surgical UVD. Controls consisted of seven healthy age-matched subjects. The LVOR was evoked by directionally random, transient whole body interaural (heave) ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2089-5
更新日期：2005-03-01 00:00:00
abstract：:The possibility of a cerebellar linkage, via the thalamus with medial area 6 of the cerebral cortex was further explored in the present experiments (cf. preceding companion paper). It was found that HRP conjugated to the lectin wheat germ agglutinin injected into motor cortical areas was transported beyond the thalamu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237671
更新日期：1985-01-01 00:00:00
abstract：:Objective attempts to characterize postural control in subjects with cerebellar (Cb) pathology have focused primarily on sagittal plane responses to static standing, semi-dynamic standing, and platform perturbation. Repeated, dynamic, functional movement may provide a better opportunity to study the effects of ataxia ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002219900291
更新日期：2000-05-01 00:00:00
abstract：:We examined ERP responses during the generation of word associates or mental images in response to concrete and abstract concepts. Of interest were the predictions of dual coding theory (DCT), which proposes that processing lexical concepts depends on functionally independent but interconnected verbal and nonverbal sy...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2734-8
更新日期：2011-07-01 00:00:00
abstract：:Our previous study showed that a fully flexed or extended hand became perceived as an extended or flexed 'phantom' hand as ischemic anesthesia progressed (Inui et al. in J Physiol 589:5775-5784, 2011). Here, we examined what happened if the hand was held in the midposition before and during the anesthesia. Twenty heal...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3040-9
更新日期：2012-05-01 00:00:00
abstract：:Adequate postural control is a prerequisite for daily activities such as reaching for an object. However, knowledge on the relationship between postural adjustments and the quality of reaching movements during human ontogeny is scarce. Therefore we evaluated the development of the relationship between the kinematic fe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0964-6
更新日期：2007-08-01 00:00:00
abstract：:A number of perceptual and neurophysiological studies have investigated the effects of delivering unilateral versus bilateral tactile sensory stimulation. While a number of studies indicate that perceptual discrimination degrades with opposite-hand stimulation, there have been no reports that examined the digit specif...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-4045-3
更新日期：2014-11-01 00:00:00
abstract：:Aerobic exercise can enhance neuroplasticity although presently the neural mechanisms underpinning these benefits remain unclear. One possible mechanism is through effects on primary motor cortex (M1) function via down-regulation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). The aim of the present...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4767-5
更新日期：2016-12-01 00:00:00
abstract：:The effects of an external constant force bias on the information transmitted (Ti) by the direction of isometric force exerted in 2-dimensional (2-D) space by human subjects were studied using an isometric manipulandum and random dot stereograms generated in a color display (Massey et al. 1988, Massey et al. 1990). Su...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231171
更新日期：1991-01-01 00:00:00
abstract：:Recent studies have demonstrated that dyslexia is associated with deficits in the temporal encoding of sensory information. While most previous studies have focused on information processing within a single sensory modality, it is clear that the deficits seen in dyslexia span multiple sensory systems. Surprisingly, al...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-005-2387-6
更新日期：2005-10-01 00:00:00
abstract：:We recorded from 389 "reach" neurons (two monkeys) in the superior colliculus (SC) and underlying reticular formation (RF) or adjacent periaqueductal grey, whose activity was related to visually guided arm movements. Reach neurons were present from approximately 0.7 mm down to a depth of 6 mm below the surface of the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005691
更新日期：1997-06-01 00:00:00
abstract：:The actions of alpha-kainic acid (KA) were reexamined in thin sections of the hippocampus and the cerebellum of the guinea pig in view of various discrepancies between our previous findings and reports from other laboratories. Brief pulses of KA ejected in st. lucidum in the CA3 region induced short- and long-lasting ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248508
更新日期：1988-01-01 00:00:00
