Abstract：
:Contact sensitization by epicutaneous application of picryl chloride causes in mice a significant reduction of the antibody responses to immunogenic TNP-conjugates. This split unresponsiveness is along-lasting. It was found that hapten applied on the skin became attached to the serum proteins and the transfer of such a serum into normal recipients, while not influencing the ability of these animals to become contact-sensitized to PCl, rendered them unable to mount the anti-TNP antibody response. Possible mechanisms of split unresponsiveness to the TNP determinant induced by PCl treatment are suggested.
journal_name
Immunologyjournal_title
Immunologyauthors
Rózycka D,Ptak Wsubject
Has Abstractpub_date
1978-08-01 00:00:00pages
229-35issue
2eissn
0019-2805issn
1365-2567journal_volume
35pub_type
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